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Sarcopenia in the elderly

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https://www.readbyqxmd.com/read/29682215/oxidative-stress-role-of-physical-exercise-and-antioxidant-nutraceuticals-in-adulthood-and-aging
#1
REVIEW
Carolina Simioni, Giorgio Zauli, Alberto M Martelli, Marco Vitale, Gianni Sacchetti, Arianna Gonelli, Luca M Neri
Physical exercise is considered to be one of the beneficial factors of a proper lifestyle and is nowadays seen as an indispensable element for good health, able to lower the risk of disorders of the cardiovascular, endocrine and osteomuscular apparatus, immune system diseases and the onset of potential neoplasms. A moderate and programmed physical exercise has often been reported to be therapeutic both in the adulthood and in aging, since capable to promote fitness. Regular exercise alleviates the negative effects caused by free radicals and offers many health benefits, including reduced risk of all-cause mortality, sarcopenia in the skeletal muscle, chronic disease, and premature death in elderly people...
March 30, 2018: Oncotarget
https://www.readbyqxmd.com/read/29680239/protein-and-peptides-for-elderly-health
#2
Nan Shang, Chalamaiah Meram, Nandika Bandara, Jianping Wu
The world is aging rapidly; thus, the management of elderly health at an advanced age poses a new research challenge. The elderly is vulnerable to not only malnutrition but also hypofunction of all organs and a variety of chronic diseases such as sarcopenia, osteoporosis, gastrointestinal dysfunction, and mental problems. As the major macronutrient, food protein plays an important role in elderly health and well-being. In this chapter, the function of protein and peptide in elderly health as well as their effects on preventing aging-related disease is reviewed...
2018: Advances in Protein Chemistry and Structural Biology
https://www.readbyqxmd.com/read/29673541/appropriate-protein-intake-is-one-strategy-in-the-management-of-metabolic-syndrome-in-korean-elderly-to-mitigate-changes-in-body-composition
#3
Chorong Oh, Jae-Kyung No
Higher protein intake could reduce metabolic syndrome (MetS) by managing body composition among Korean elderly although the research is scant. Herein, we examined the hypothesis that the optimal protein intake of Korean elderly is associated with both improvements in MetS risk as well as favorable changes in body composition. The present study employs a national data source, the Korea National Health and Nutrition Examination Survey (KNHANES, 2009), and a total 1,567 elderly (651 men and 916 women) were included in the final data analyses...
March 2018: Nutrition Research
https://www.readbyqxmd.com/read/29673501/association-of-sarcopenia-with-nutritional-parameters-quality-of-life-hospitalization-and-mortality-rates-of-elderly-patients-on-hemodialysis
#4
Juliana Giglio, Maria Ayako Kamimura, Fernando Lamarca, Juliana Rodrigues, Fernanda Santin, Carla Maria Avesani
OBJECTIVE: This study aimed to assess whether diminished muscle mass, diminished muscle strength, or both conditions (sarcopenia) are associated with worse nutritional status, poor quality of life (QoL), and hard outcomes, such as hospitalization and mortality, in elderly patients on maintenance hemodialysis (MHD). DESIGN AND SUBJECTS: This is a multicenter observational longitudinal study that included 170 patients on MHD (age 70 ± 7 years, 65% male) from 6 dialysis centers...
May 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29671766/protein-intake-and-distribution-in-relation-to-physical-functioning-and-quality-of-life-in-community-dwelling-elderly-people-acknowledging-the-role-of-physical-activity
#5
Dominique S M Ten Haaf, Ellen J I van Dongen, Malou A H Nuijten, Thijs M H Eijsvogels, Lisette C P G M de Groot, Maria T E Hopman
Increasing total protein intake and a spread protein intake distribution are potential strategies to attenuate sarcopenia related loss of physical function and quality of life. The aim of this cross-sectional study was to investigate whether protein intake and protein intake distribution are associated with muscle strength, physical function and quality of life in community-dwelling elderly people with a wide range of physical activity. Dietary and physical activity data were obtained from two studies (N = 140, age 81 ± 6, 64% male), with the following outcome measures: physical functioning (Short Physical Performance Battery (SPPB), comprising balance, gait speed and chair rise tests), handgrip strength and quality of life (EQ-5D-5L)...
April 19, 2018: Nutrients
https://www.readbyqxmd.com/read/29655775/relationship-between-water-intake-and-skeletal-muscle-mass-in-elderly-koreans-a-nationwide-population-based-study
#6
Jun-Il Yoo, Hana Choi M D, Sang-Yoon Song, Ki-Soo Park, Dong-Hoon Lee, Yong-Chan Ha
OBJECTIVES: The purposes of this study were to evaluate the correlation between sarcopenia and water intake and investigate lack of daily water intake in the presence of sarcopenia in an elderly population. METHODS: Data from 3656 participants (1582 men and 2074 women) were analyzed using the Korea National Health and Nutrition Examination Survey. Sarcopenia was defined in accordance with the criteria of the Asia Working Group for Sarcopenia. Water intake was assessed using the dietary water adequacy ratio and was calculated by dividing the daily water intake from fluid by the recommended daily amount of 1000 mL in men and 900 mL in women...
February 12, 2018: Nutrition
https://www.readbyqxmd.com/read/29624960/associated-factors-with-sarcopenia-among-mexican-elderly-2012-national-health-and-nutrition-survey
#7
(no author information available yet)
Background: Sarcopenia involves the loss of skeletal muscle mass and age-related functionality; it diminishes physical independence, health and quality of life. In 2016 it was added to the International Classification of Diseases (ICD-10). Information about the frequency of sarcopenia among Mexican older adults is scarce. The objective was to analyze associated factors with sarcopenia in Mexican older adults through the 2012 National Health and Nutrition Survey data. Methods: Cross-sectional study which included subjects of 60 years of age or more with simultaneous information on health and anthropometry questionnaires from the 2012 National Health and Nutrition Survey...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29624343/oxidative-stress-in-the-elderly-with-diabetes-mellitus-or-hypertension
#8
Aleida Rodríguez-Castañeda, Katia Leticia Martínez-González, Rosalinda Sánchez-Arenas, Sergio Sánchez-García, Israel Grijalva, Lourdes Basurto-Acevedo, Juan Cuadros-Moreno, Eliseo Ramírez-García, Paola García-de la Torre
Background: Mexico City has the highest aging rate in the country, as well as a high prevalence of diabetes mellitus (DM) and hypertension (HT). It is known that each one of these conditions increase oxidative stress (OS) independently. Methods: With this study we described changes in OS of 18 patients without DM or HT (controls), 12 with DM, 23 with HT, and 18 with DM and HT, all of them members of the COSFAMM (Cohorte de Obesidad, Sarcopenia y Fragilidad en Adultos Mayores de México)...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29623651/is-iron-accumulation-a-possible-risk-factor-for-sarcopenia
#9
Guoyang Zhao
Sarcopenia has a high incidence among the elderly, with significant negative effects on the quality of life. The pathogenesis of sarcopenia is complex, and many factors are involved in its development and progression. Sarcopenia might be associated with iron accumulation given that (1) age-related iron accumulation was found in the skeletal muscle, (2) excess iron could cause skeletal muscle damage or atrophy, and (3) patients with sarcopenia showed higher levels of serum ferritin. Understanding the etiology and pathogenesis of sarcopenia would help to develop new treatment and preventive methods, thereby improving the quality of life of the elderly patients...
April 5, 2018: Biological Trace Element Research
https://www.readbyqxmd.com/read/29619149/appendicular-skeletal-muscle-mass-reference-values-and-the-peak-muscle-mass-to-identify-sarcopenia-among-iranian-healthy-population
#10
Gita Shafiee, Afshin Ostovar, Ramin Heshmat, Abbas Ali Keshtkar, Farshad Sharifi, Zhaleh Shadman, Iraj Nabipour, Akbar Soltani, Bagher Larijani
Background: Sacopenia is a common problem in elderly with the adverse outcomes. The objective of this study was to estimate the peak appendicular skeletal muscle mass (ASM) and age of its attainment by sex among the Iranian population. Methods: A total of 691 men and women aged 18-94 years participated in this cross-sectional, population-based study in Bushehr, Iran. ASM was measured by dual X-ray absorptiometry. Cutoff points for men and women were established considering two standard deviations (SDs) below the mean values of the skeletal muscle index (SMI) for young reference groups...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29614534/-current-concepts-of-cardiologic-therapies-in-the-elderly
#11
Ursula Müller-Werdan, Kristina Norman
MYOCARDIAL INFARCTION IN THE OLD PATIENT: Even old patients may crucially benefit from reopening the occluded coronary artery by percutaneous coronary intervention with stent implantation. Bleeding complications can be reduced by choosing the radial instead of the femoral vascular approach for cardiac catheterization. STATINS FOR THE ELDERLY: WHEN TO START UND WHEN TO STOP?: Elderly benefit no less than the younger from statins. "Goal-oriented statin therapy" is preferable to the "statin strategy of fixed dose"...
April 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29604401/limb-muscle-quality-and-quantity-in-elderly-adults-with-dynapenia-but-not-sarcopenia-an-ultrasound-imaging-study
#12
Ke-Vin Chang, Wei-Ting Wu, Kuo-Chin Huang, Wei Han Jan, Der-Sheng Han
BACKGROUND: Dynapenia is prevalent in people with reduced skeletal muscle mass, i.e. sarcopenia, but a certain population develops muscle strength loss despite having normal skeletal muscle volume. To date, studies investigating muscle quality and quantity in groups with dynapenia but not sarcopenia are limited. METHODS: Echogenicity and thickness of the biceps brachii, triceps brachii, rectus femoris, and medial gastrocnemius muscles were measured using high-resolution ultrasonography in 140 community-dwelling elderly adults...
March 28, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29604268/mild-aerobic-training-with-blood-flow-restriction-increases-the-hypertrophy-index-and-musk-in-both-slow-and-fast-muscles-of-old-rats-role-of-pgc-1%C3%AE
#13
Mohammad-Ali Bahreini Pour, Siyavash Joukar, Fariborz Hovanloo, Hamid Najafipour, Vida Naderi, Alireza Raji, Saeed Esmaeili-Mahani
AIMS: Existing evidence emphasize the role of mitochondrial dysfunction in sarcopenia which is revealed as loss of skeletal muscle mass and neuromuscular junction remodeling. We assessed the effect of low-intensity aerobic training along with blood flow restriction on muscle hypertrophy index, muscle-specific kinase (MuSK), a pivotal protein of the neuromuscular junction and Peroxisome proliferator-activated receptor gamma co-activator 1-alpha (PGC-1α) in aged male rats. MAIN METHODS: Animals groups were control (CTL), sham (Sh), leg blood flow restriction (BFR), exercise (Ex), sham + exercise (Sh + Ex), and BFR plus exercise (BFR + Ex) groups...
March 28, 2018: Life Sciences
https://www.readbyqxmd.com/read/29596212/perioperative-nutritional-optimization-in-spine-surgery
#14
Rabia Qureshi, Mohammad Rasool, Varun Puvanesarajah, Hamid Hassanzadeh
Nutritional optimization in patients undergoing spine surgery is important as improved surgical outcomes and decreased rates of complications have been noted in optimized patients. With the increasingly high numbers of elderly patient and patients with metabolic comorbidities undergoing spine procedures, perioperative nutritional status should be enhanced for the best possible surgical outcomes. Methods of optimization include preoperative screening with Nutritional Risk Score or other scoring systems, looking for changes in body mass index, detecting sarcopenia, and screening for metabolic abnormalities...
April 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29590170/histologic-subtypes-are-not-associated-with-the-presence-of-sarcopenia-in-lung-cancer
#15
Chang Rae Kim, Eun Young Kim, Young Saing Kim, Hee Kyung Ahn, Kun Woo Kim, Yu Mi Jeong, Jeong Ho Kim
BACKGROUND: Sarcopenia is prevalent and a known adverse prognostic effector in lung cancer (LCA). However, the relationship between sarcopenia and histology remains uncertain in LCA. METHODS: Consecutive patients with newly diagnosed LCA (n = 778) between June 2012 and February 2015 were retrospectively reviewed to identify factors associated with sarcopenia. Sarcopenia was defined as CT-determined L3 muscle index (muscle area at L3/height2) of < 55 cm2/m2 for men and < 39 cm2/m2 for women...
2018: PloS One
https://www.readbyqxmd.com/read/29587829/how-do-we-define-and-measure-sarcopenia-protocol-for-a-systematic-review
#16
Paulo Roberto Carvalho do Nascimento, Stéphane Poitras, Martin Bilodeau
BACKGROUND: The loss of muscle mass is a natural aging consequence. A reduction of muscle mass that surpasses the physiological rate is considered the key factor responsible for the development of a geriatric syndrome called sarcopenia. However, a new understanding of the importance of muscle quality over quantity is rising; as a result, different definitions for sarcopenia has been used. Due to the negative impact on elder's health and quality of life, the number of research investigating the causes, prevalence, and management of sarcopenia is increasing, although a consensus on sarcopenia definition is still missing...
March 27, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29582895/-feeling-more-self-confident-cheerful-and-safe-experiences-from-a-health-promoting-intervention-in-community-dwelling-older-adults-a-qualitative-study
#17
Å von Berens, A Koochek, M Nydahl, R A Fielding, T Gustafsson, D R Kirn, T Cederholm, M Södergren
OBJECTIVES: Studies show that regular exercise in combination with nutritional support can be effective in managing sarcopenia, which is age-related involuntary loss of skeletal muscle mass and strength. Qualitative investigations of participants' experiences from interventions in this domain are scarce. In this study, we explored older persons' experiences from an intervention designed to prevent sarcopenia, with the aim of capturing the participants' thoughts and opinions. DESIGN: A qualitative study embedded in the multicenter randomized clinical trial The Vitality and Vigor in the Elderly study, VIVE2...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29564306/sarcopenic-obesity-in-elderly-korean-women-a-nationwide-cross-sectional-study
#18
Young Nam Kwon, Sung Sang Yoon, Kyung-Hag Lee
Background: Sarcopenia causes loss of muscle mass in the elderly and is associated with development of metabolic syndrome in those with obesity. This study evaluated the prevalence of sarcopenic obesity (SO) in healthy Korean elderly women. Methods: This study was based on data from the Korea National Health and Nutrition Examination Survey IV and V, 2008-2011. Whole body dual energy X-ray absorptiometry and body mass index measurement were performed for all patients...
February 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29564302/new-skeletal-muscle-mass-index-in-diagnosis-of-sarcopenia
#19
Jeong Jae Moon, Sam-Guk Park, Seung Min Ryu, Chan-Ho Park
Background: We sought to develop a novel index based on the skeletal muscle mass that reflects the change of quality of life (QOL), and is the most appropriate index for the body composition of the elderly in Korea. Whether lower extremity skeletal muscle mass index (LESMI) is an appropriate novel new index to diagnose patients with sarcopenia was also evaluated. A cut-off value for each index was reported to facilitate the diagnosis of patients with sarcopenia in a Korean population...
February 2018: Journal of Bone Metabolism
https://www.readbyqxmd.com/read/29564300/review-of-epidemiology-diagnosis-and-treatment-of-osteosarcopenia-in-korea
#20
REVIEW
Jun-Il Yoo, Yong-Chan Ha
Sarcopenia was listed in the International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) as M62.84, on October 1, 2016. Sarcopenia is primarily associated with metabolic diseases, such as diabetes, obesity, and cachexia, as well as chronic renal failure, congestive heart failure, and chronic obstructive pulmonary disease. Sarcopenia is also significantly associated with osteoporosis in elderly populations and the combined disease is defined as osteosarcopenia. Several studies have confirmed that sarcopenia and osteoporosis (osteosarcopenia) share common risk factors and biological pathways...
February 2018: Journal of Bone Metabolism
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