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Sarcopenia in the elderly

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https://www.readbyqxmd.com/read/29228514/gait-speed-predicts-post-operative-medical-complications-in-elderly-gastric-cancer-patients-undergoing-gastrectomy
#1
Arvine Chandoo, Chu-Huai Chi, Weiping Ji, Yingpeng Huang, Xiao-Dong Chen, Wei-Teng Zhang, Rui-Sen Wu, Xian Shen
BACKGROUND: Gait speed is a clinical outcome that can measure the physical performance of elderly gastric patients. The purpose of this study was to determine the importance of gait speed in predicting post-operative morbidities in elderly patients undergoing curative gastrectomy. METHODS: We conducted a prospective study of 357 elderly patients (≥65 years old) undergoing curative gastrectomy. Preoperative gait speed was measured in a 6-m well-lit and unobstructed hallway...
December 11, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29214748/alterations-in-the-in-vitro-and-in-vivo-regulation-of-muscle-regeneration-in-healthy-ageing-and-the-influence-of-sarcopenia
#2
Joanna Brzeszczyńska, Angelika Meyer, Robin McGregor, Alain Schilb, Simone Degen, Valentina Tadini, Neil Johns, Ramon Langen, Annemie Schols, David J Glass, Ronenn Roubenoff, James A Ross, Kenneth C H Fearon, Carolyn A Greig, Carsten Jacobi
BACKGROUND: Sarcopenia is defined as the age-related loss of skeletal muscle mass and function. While all humans lose muscle with age, 2-5% of elderly adults develop functional consequences (disabilities). The aim of this study was to investigate muscle myogenesis in healthy elderly adults, with or without sarcopenia, compared with middle-aged controls using both in vivo and in vitro approaches to explore potential biomarker or causative molecular pathways associated with sarcopenic versus non-sarcopenic skeletal muscle phenotypes during ageing...
December 6, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29212996/-a-comparison-of-the-associations-of-dynapenia-and-sarcopenia-with-fear-of-falling-in-elderly-diabetic-patients
#3
Satoshi Ida, Kazuya Murata, Yuki Ishihara, Kanako Imataka, Ryutaro Kaneko, Ryoko Fujiwara, Hiroka Takahashi
AIM: To comparatively investigate whether dynapenia and sarcopenia, as defined by the Asian Working Group for Sarcopenia (AWGS), are associated with fear of falling in elderly patients with diabetes. METHODS: The subjects were outpatients with diabetes who were at least 65 years of age when they visited our hospital. Sarcopenia was evaluated based on the AWGS definition. The cutoff values for the appendicular skeletal mass index (multi-frequency bioelectrical impedance method), grip strength, and walking speed were, respectively, 7...
2017: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/29209478/association-between-sarcopenia-and-dipstick-proteinuria-in-the-elderly-population-the-korea-national-health-and-nutrition-examination-surveys-2009-2011
#4
Duna Hwang, Mi-Ryung Cho, Minyong Choi, Sang Hyun Lee, Youngmin Park
Background: Sarcopenia and proteinuria are significant health difficulties in the elderly; however, few studies have investigated their relationship. In this study, we investigated the association between sarcopenia and proteinuria in Korean subjects over 60 years old. Methods: We included data from the Korean National Health and Nutrition Examination Survey, a cross-sectional, nationally representative survey conducted from 2009 to 2011 (n=4,008). Sarcopenia was defined using appendicular skeletal muscle mass as a percentage of body weight...
November 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29205449/the-relationship-between-jaw-opening-force-and-the-cross-sectional-area-of-the-suprahyoid-muscles-in-healthy-elderly
#5
Eriko Kajisa, Haruka Tohara, Ayako Nakane, Yoko Wakasugi, Koji Hara, Kohei Yamaguchi, Kanako Yoshimi, Shunsuke Minakuchi
We conducted a clinical cross-sectional study to examine the relationship between jaw-opening force and the cross-sectional area of the suprahyoid muscles and whole skeletal muscle mass. Subjects were healthy 39 males and 51 females without dysphagia and sarcopenia, aged 65 years and older. Jaw-opening force was measured three times using a jaw-opening sthenometer; the maximal of these three was taken as the measurement value. The cross-sectional area of the geniohyoid and anterior belly of the digastric muscles was evaluated using ultrasonography...
December 4, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29200625/large-calf-circumference-indicates-non-sarcopenia-despite-body-mass
#6
Satomi Kusaka, Tetsuya Takahashi, Yoshinori Hiyama, Yasuaki Kusumoto, Junko Tsuchiya, Masaru Umeda
[Purpose] The purpose of this study is to evaluate the applicability of the calf circumference as a tool for screening sarcopenia. [Subjects and Methods] One hundred sixteen community-dwelling elderly females were enrolled. Calf circumference of the dominant leg was measured using a plastic measuring tape. Subjects were divided into 3 groups based on body mass index (BMI); subjects with the values for BMI <18.5 kg/m2; those with BMI 18.5 to 25.0; those with BMI ≥25.0 kg/m2. Positive predictive value and negative predictive value of sarcopenia were calculated based on the obtained cut off values of calf circumference and the diagnosis of sarcopenia in each group...
November 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29183520/the-effect-of-sarcopenia-on-outcomes-in-geriatric-blunt-trauma
#7
Mahdi Malekpour, Kelly Bridgham, Kathryn Jaap, Ryan Erwin, Kenneth Widom, Megan Rapp, Diane Leonard, Susan Baro, James Dove, Marie Hunsinger, Joseph Blansfield, Mohsen Shabahang, Denise Torres, Jeffrey Wild
Elderly patients are at a higher risk of morbidity and mortality after trauma, which is reflected through higher frailty indices. Data collection using existing frailty indices is often not possible because of brain injury, dementia, or inability to communicate with the patient. Sarcopenia is a reliable objective measure for frailty that can be readily assessed in CT imaging. In this study, we aimed to evaluate the effect of sarcopenia on the outcomes of geriatric blunt trauma patients. Left psoas area (LPA) was measured at the level of the third lumbar vertebra on the axial CT images...
November 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29172406/the-impact-of-sarcopenia-on-health-related-quality-of-life-in-elderly-people-korean-national-health-and-nutrition-examination-survey
#8
Der Sheng Sun, Hyunyong Lee, Hyeon Woo Yim, Hye Sung Won, Yoon Ho Ko
Background/Aims: The purpose of the study is to investigate the associations between sarcopenia and health-related quality of life in elderly men and women in Korea. Methods: In a cross-sectional study using data from 2008 to 2011 Korean National Health and Nutrition Examination Survey, 4,937 adults aged 60 years and older who underwent a dual-energy X-ray absorptiometry scan were included in the study. Sarcopenia is defined as an appendicular skeletal muscle index of two standard deviations or more below the mean for young, healthy reference populations...
November 27, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29165153/impact-of-single-nucleotide-polymorphism-on-short-stature-and-reduced-tongue-pressure-among-community-dwelling-elderly-japanese-participants-a-cross-sectional-study
#9
Yuji Shimizu, Shimpei Sato, Yuko Noguchi, Jun Koyamatsu, Hirotomo Yamanashi, Miho Higashi, Mako Nagayoshi, Koichiro Kadota, Shin-Ya Kawashiri, Yasuhiro Nagata, Noboru Takamura, Takahiro Maeda
BACKGROUND: Asian-specific single nucleotide polymorphism (SNPs) (rs3782886) is reported to be associated with myocardial infarction; sarcopenia is reported to be associated with coronary subclinical atherosclerosis. On the other hand, short stature has been revealed as an independent risk factor for cardiovascular disease. However, no studies have reported on the association between sarcopenia and short stature nor on the impact of rs3782886 on this association. METHODS: Since reduced maximum voluntary tongue pressure against the palate (MTP) reflects one aspect of sarcopenia, we conducted a cross-sectional study of 537 community-dwelling elderly Japanese participants aged 60-89 years who had participated in a general health checkup in 2015...
July 27, 2017: Environmental Health and Preventive Medicine
https://www.readbyqxmd.com/read/29161342/oral-frailty-as-a-risk-factor-for-physical-frailty-and-mortality-in-community-dwelling-elderly
#10
Tomoki Tanaka, Kyo Takahashi, Hirohiko Hirano, Takeshi Kikutani, Yutaka Watanabe, Yuki Ohara, Hiroyasu Furuya, Tetsuo Tsuji, Masahiro Akishita, Katsuya Iijima
Background: Oral health is important for maintaining general health among the elderly. However, a longitudinal association between poor oral health and general health has not been reported. We investigated whether poor oral status can predict physical weakening (physical frailty, sarcopenia, subsequent disability) and identified the longitudinal impact of the accumulated poor oral health (i.e., oral frailty) on adverse health outcomes, including mortality. Methods: A total of 2,011 elderly individuals (aged ≥65 years) participated in the baseline survey of the Kashiwa study in 2012...
November 17, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29156926/-oral-feeding-and-nutritional-improvement-in-hospitals-and-residential-care-homes-industry-innovations
#11
Rosa M Ortega, Ana Isabel Jiménez Ortega, José Miguel Perea Sánchez, Esther Cuadrado Soto, Rosa M Martínez García, Ana M López Sobaler
OBJECTIVES: Inpatient and institutionalized elderly patients are population groups vulnerable from the nutritional point of view because oftheir greater risk of deficiencies and because in them the effects of imbalances are more serious than in other groups. Analyzing the possible usefulness of industry innovations offering solutions in the oral feeding of these population groups constitutes the objective of the present work. METHODS: Bibliographic search related to the topic...
October 15, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29154428/muscle-wasting-and-sarcopenia-in-heart-failure-and-beyond-update-2017
#12
REVIEW
Jochen Springer, Joshua-I Springer, Stefan D Anker
Sarcopenia (loss of muscle mass and muscle function) is a strong predictor of frailty, disability and mortality in older persons and may also occur in obese subjects. The prevalence of sarcopenia is increased in patients suffering from chronic heart failure. However, there are currently few therapy options. The main intervention is resistance exercise, either alone or in combination with nutritional support, which seems to enhance the beneficial effects of training. Also, testosterone has been shown to increased muscle power and function; however, a possible limitation is the side effects of testosterone...
November 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/29151281/skeletal-muscle-performance-and-ageing
#13
REVIEW
Michael Tieland, Inez Trouwborst, Brian C Clark
The world population is ageing rapidly. As society ages, the incidence of physical limitations is dramatically increasing, which reduces the quality of life and increases healthcare expenditures. In western society, ~30% of the population over 55 years is confronted with moderate or severe physical limitations. These physical limitations increase the risk of falls, institutionalization, co-morbidity, and premature death. An important cause of physical limitations is the age-related loss of skeletal muscle mass, also referred to as sarcopenia...
November 19, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/29141602/association-between-sarcopenia-and-low-back-pain-in-local-residents-prospective-cohort-study-from-the-gaina-study
#14
Shinji Tanishima, Hiroshi Hagino, Hiromi Matsumoto, Chika Tanimura, Hideki Nagashima
BACKGROUND: Low back pain (LBP) is one of the most common ailments that people experience in their lifetime. On the other hands, Sarcopenia also leads to several physical symptoms and contributes to reducing the quality of life of elderly people.The purpose of this study is to investigate the association between sarcopenia and low back pain among the general population. METHODS: The subjects included 216 adults (79 men and 137 women; mean age, 73.5 years) undergoing a general medical examination in Hino, Japan...
November 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29127513/pentosidine-concentration-is-associated-with-degenerative-lumbar-scoliosis-in-older-women-preliminary-results
#15
Yawara Eguchi, Toru Toyoguchi, Kazuhide Inage, Kazuki Fujimoto, Sumihisa Orita, Kazuyo Yamauchi, Miyako Suzuki, Hirohito Kanamoto, Koki Abe, Masaki Norimoto, Tomotaka Umimura, Masao Koda, Takeo Furuya, Yasuchika Aoki, Kazuhisa Takahashi, Seiji Ohtori
PURPOSE: Advanced glycation end products (AGEs) have been implicated in the pathogenesis of sarcopenia. The objective of the study was to investigate the prevalence of sarcopenia in degenerative lumbar scoliosis (DLS), and the relationship between biochemical markers including major AGEs, pentosidine, and DLS in older women. METHODS: Our study participants were 20 elderly women with idiopathic DLS (mean age 76.4 years, range 56-88). Nineteen age- and sex-matched volunteers (mean age 74...
November 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29120677/relationships-between-25-oh-d-concentration-sarcopenia-and-homa-ir-in-postmenopausal-korean-women
#16
J H Lee, S Kim, M K Kim, B H Yun, S Cho, Y S Choi, B S Lee, S K Seo
OBJECTIVE: Sarcopenia and insulin resistance are common co-morbidities in the elderly and are known to be associated with vitamin D deficiency. However, no previous studies have investigated interactions between all three of these factors. We aimed to investigate the relationship between 25-hydroxyvitamin D concentration, sarcopenia, and insulin resistance in postmenopausal Korean women. METHODS: This study used data from the Korea National Health and Nutrition Examination Survey 2008-2011...
November 9, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29093231/factors-related-with-handgrip-strength-in-elderly-patients
#17
Nur Riviati, Siti Setiati, Purwita W Laksmi, Murdani Abdullah
BACKGROUND: the aging process causes decreasing in the function of various organs. Skletal muscle is one of the organs affected by aging process. It is known as sarcopenia. Sarcopenia is defined as a syndrome characterized by progressive loss of muscle mass and strength. The handgrip strength examination is often applied as a sarcopenia filtering technique. This study aimed to determine the relationship between age, nutritional status, and chronic diseases such as stroke, hypertension (HT), diabetes mellitus (DM), coronary heart disease (CHD), and chronic obstructive pulmonary disease (COPD) with handgrip strength...
July 2017: Acta Medica Indonesiana
https://www.readbyqxmd.com/read/29092672/the-impact-of-age-on-skeletal-muscle-progenitor-cell-survival-and-fate-after-injury
#18
Yu Zhou, Daniel Lovell, Maigen Bethea, Benyam Yoseph, James Poteracki, Shay Soker, Tracy Criswell
Sarcopenia is defined as the loss of skeletal muscle mass and function due to age, and represents a major cause of disability in the elderly population. The contributing factors to the onset of sarcopenia are not well defined, but appear to involve age-dependent changes in both the tissue micro-environment and muscle progenitor cell (MPC) population. MPC transplantation has the potential to be a novel therapy for treatment of muscle dysfunction due to aging or injury, but has not shown significant clinical efficacy to date...
November 1, 2017: Tissue Engineering. Part C, Methods
https://www.readbyqxmd.com/read/29079029/relationship-between-sarcopenia-and-frailty-in-the-toledo-study-of-healthy-aging-a-population-based-cross-sectional-study
#19
B Davies, F García, I Ara, F Rodríguez Artalejo, L Rodriguez-Mañas, S Walter
INTRODUCTION: Frailty and sarcopenia are correlates of musculoskeletal aging that represent a state of vulnerability increasing the risk of negative health outcomes. Standardized definitions are lacking for both, and sometimes both concepts are used interchangeably. However, no large study has assessed the coexistence of these 2 entities in a cohort of older community-dwelling people. METHODS: Data were taken from the Toledo Study of Healthy Aging (TSHA), a study of community-dwelling elderly (≥65 years)...
October 24, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/29074832/-update-on-recent-progress-in-vitamin-d-research-eldecalcitol-r-and-fall-prevention
#20
Takao Suzuki
In the elderly, vitamin D deficiency results not only in impaired bone mineralization, but also myopathy. Low vitamin D has also been shown to be associated with decline of muscle strength, sarcopenia, functional limitation, and disability. Several recent studies have shown that low serum vitamin D concentration is associated with lower physical function and falls in older adults. In this article, the author reviews a relationship between falls and serum vitamin D concentration of the elderly living in the community, and also introduces the major results from a recent randomized controlled trial on prevention of decline of fall-related balance performance by the treatment with newly developed active vitamin D(Eldecalcitol(R) )among the women with age 65 years old and over and diagnosed as osteoporosis...
2017: Clinical Calcium
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