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Frailty in the elderly

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https://www.readbyqxmd.com/read/28736037/-frequency-of-successful-aging-and-frailty-associated-risk-factors
#1
Karla Berenice Carrazco-Peña, Katia Farías-Moreno, Benjamín Trujillo-Hernández
OBJECTIVE: To determine the frequency of successful aging (SA) and its relationship with frailty in an elderly population. MATERIAL AND METHODS: An analytical cross-sectional study of subjects ≥60 years of age seen as outpatients in a general hospital. Successful aging was defined as scores of ≥ 90 in the Barthel index and ≤ 2 in the Pfeiffer test. Frailty was determined using the Fried criteria. RESULTS: The study included 400 subjects (272 women and 128 men), with a mean age of 71...
July 20, 2017: Revista Española de Geriatría y Gerontología
https://www.readbyqxmd.com/read/28724399/health-needs-access-to-healthcare-and-perceptions-of-ageing-in-an-urbanizing-community-in-india-a-qualitative-study
#2
Nandita Bhan, Pavitra Madhira, Arundati Muralidharan, Bharati Kulkarni, Gvs Murthy, Sanjay Basu, Sanjay Kinra
BACKGROUND: India's elderly population is rising at an unprecedented rate, with a majority living in rural areas. Health challenges associated with ageing, changing social networks and limited public health infrastructure are issues faced by the elderly and caregivers. We examined perceptions of health needs of the elderly across local stakeholders in an urbanizing rural area. METHODS: The qualitative study was conducted among participants in the Andhra Pradesh Children and Parents Study (APCAPS) site in Rangareddy district, Telangana...
July 19, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28721433/oral-health-and-the-frail-elderly
#3
L Rapp, S Sourdet, B Vellas, M-H Lacoste-Ferré
INTRODUCTION: The relationships between oral health conditions and frailty have rarely been explored. A systematic review of frailty components and oral health concluded that differences in study population endpoint criteria and study design cannot establish a relationship between frailty and oral health. OBJECTIVE: This study aims to describe the distribution of the OHAT (Oral Health Assessment Tool) score in a population of frail subjects and to assess associated parameters (age, socio-economic status, living conditions, education level, nutritional habits, cognitive functioning, autonomy)...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28721427/prevalence-of-frailty-in-nursing-home-residents-according-to-various-diagnostic-tools
#4
F Buckinx, J-Y Reginster, S Gillain, J Petermans, T Brunois, O Bruyère
BACKGROUND: Although the theoretical foundations of frailty are well established in the literature, it remains an evolving concept lacking any unique definition or diagnostic criteria for use in clinical practice and epidemiological research. No consensus exists about the accurate prevalence rates of frailty. The various operational definitions of frailty can at least partly explain such discrepancies. OBJECTIVE: To compare the prevalence of frailty, measured with different diagnostic tools, among elderly nursing home residents...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28721290/frailty-and-elderly-in-urology-is-there-an-impact-on-post-operative-complications
#5
Fabrizio Dal Moro, Alessandro Morlacco, Giovanni Motterle, Lisa Barbieri, Filiberto Zattoni
INTRODUCTION: Frailty used as predictive tool is still not carried out in daily practice, although many studies confirm the great clinical importance of the frailty syndrome in surgical outcomes. There is no standardized method of measuring the physiological reserves of older surgical patients. The aim of this study was to analyze a cohort of older urological patients according to various frailty indices, in order to evaluate whether they are predictors of post-operative complications after urological procedures...
June 30, 2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28716855/frailty-screening-tools-for-elderly-patients-incident-to-dialysis
#6
Ismay N van Loon, Namiko A Goto, Franciscus T J Boereboom, Michiel L Bots, Marianne C Verhaar, Marije E Hamaker
BACKGROUND AND OBJECTIVES: A geriatric assessment is an appropriate method for identifying frail elderly patients. In CKD, it may contribute to optimize personalized care. However, a geriatric assessment is time consuming. The purpose of our study was to compare easy to apply frailty screening tools with the geriatric assessment in patients eligible for dialysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: A total of 123 patients on incident dialysis ≥65 years old were included <3 weeks before to ≤2 weeks after dialysis initiation, and all underwent a geriatric assessment...
July 17, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28712144/frailty-is-an-independent-prognostic-marker-in-elderly-patients-with-myocardial-infarction
#7
Gonzalo Luis Alonso Salinas, Marcelo Sanmartin, Marina Pascual Izco, Luis Miguel Rincon, Pablo Pastor Pueyo, Alvaro Marco Del Castillo, Alberto Garcia Guerrero, Pedro Caravaca Perez, Alejandro Recio-Mayoral, Asuncion Camino, Manuel Jimenez-Mena, José Luis Zamorano
BACKGROUND: Acute coronary syndrome (ACS) patients are increasingly older. Conventional prognostic scales include chronological age but do not consider vulnerability. In elderly patients, a frail phenotype represents a better reflection of biological age. HYPOTHESIS: This study aims to determine the prevalence of frailty and its influence on patients age ≥75 years with ACS. METHODS: Patients age ≥75 years admitted due to type 1 myocardial infarction were included in 2 tertiary hospitals, and clinical data were collected prospectively...
July 16, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28709946/frailty-and-sarcopenia-do-not-predict-adverse-events-in-an-elderly-population-undergoing-non-complex-primary-elective-surgery-for-degenerative-conditions-of-the-lumbar-spine
#8
Raphaële Charest-Morin, John Street, Honglin Zhang, Taren Roughead, Tamir Ailon, Michael Boyd, Marcel Dvorak, Brian Kwon, Scott Paquette, Nicolas Dea, Charles G Fisher, Alana M Flexman
BACKGROUND CONTEXT: Sarcopenia measured by normalized total psoas area (NTPA) has been shown to predict mortality and adverse events (AE) in numerous surgical populations. The relationship between sarcopenia and postoperative outcomes after surgery for degenerative spine disease (DSD) has not been investigated. PURPOSE: This study aimed to determine the relationships between sarcopenia, frailty and postoperative adverse events in the elderly DSD population. Secondary objectives were to describe the distribution and predictors of NTPA and to determine the relationship between sarcopenia, frailty and length of stay, discharge to a facility and in-hospital mortality...
July 11, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28705733/platelet-oxidative-stress-as-a-novel-target-of-cardiovascular-risk-in-frail-older-people
#9
REVIEW
Francisco Fuentes, Iván Palomo, Eduardo Fuentes
The average lifespan of humans and the percentage of people entering the 65 and older age group are growing rapidly. Within this age group, cardiovascular diseases (CVD) increase steeply and are the most common cause of death. During aging, experimental and clinical studies support the pivotal role played by reactive oxidant species in the mechanism of platelet activation. Frailty has been implicated as a causative and prognostic factor in patients with CVD. Oxidative stress is increased in frail older people, and may lead to accelerated aging and higher incidence of oxidative diseases such as CVD...
July 11, 2017: Vascular Pharmacology
https://www.readbyqxmd.com/read/28704826/dialysis-in-the-elderly-and-impact-of-institutionalization-in-the-united-states-renal-data-system
#10
Amarpali Brar, Mary Mallappallil, Dimitre G Stefanov, David Kau, Moro O Salifu
BACKGROUND: We hypothesized that in the very elderly dialysis patients in the United States, institutionalization in nursing homes would increase mortality in addition to age alone. METHODS: Incident dialysis patients from 2001 to 2008 above the age of 70 were included. Patients above 70 were categorized into 4 groups according to age as 70-75, 76-80, 81-85, and >85 years and further divided into institutionalized and noninstitutionalized. Kaplan-Meier survival curves were plotted to assess patient survival...
July 14, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28700679/aged-associated-cytomegalovirus-and-epstein-barr-virus-reactivation-and-cytomegalovirus-relationship-with-the-frailty-syndrome-in-older-women
#11
Ronaldo Luis Thomasini, Daniele Sirineu Pereira, Fabiana Souza Máximo Pereira, Elvis Cueva Mateo, Thamires Nader Mota, Gabrielle Gontijo Guimarães, Leani Souza Máximo Pereira, Cristiano Xavier Lima, Mauro Martins Teixeira, Antônio Lúcio Teixeira
Immunosenescence is an age-related reduction of immune system activity that can be associated with frailty. This study aimed to compare cytomegalovirus (CMV) and Epstein-Barr virus (EBV) reactivations (based on viremias) between young and elderly women who had a chronic CMV and/or EBV infection (i.e., an IgG+ serostatus) without an acute infection (i.e., an IgM- serostatus), and among the elderly group categorized according to frailty status. DNA was extracted from plasma using standard protocols and serostatus was determined by enzyme-linked immunosorbent assay...
2017: PloS One
https://www.readbyqxmd.com/read/28699992/changes-in-frailty-conditions-and-phenotype-components-in-elderly-after-hospitalization
#12
Gianna Fiori Marchiori, Darlene Mara Dos Santos Tavares
Objective: describing the changes in frailty conditions over the period of a year after hospital discharge, verifying predictive variables for changes in frailty conditions and frailty phenotype components according to worsening, improving and stable groups. Method: a longitudinal survey carried out with 129 elderly. A structured form for socioeconomic and health data, scales (Geriatric Depression Scale - short form, Katz scale, Lawton and Brody scale) and frailty phenotype according to Fried were used...
July 10, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28697791/blood-transfusion-in-elderly-patients-with-chronic-anemia-a-qualitative-analysis-of-the-general-practitioners-attitudes
#13
Sylvain Le Calvé, Dominique Somme, Joaquim Prud'homm, Aline Corvol
BACKGROUND: Blood transfusion in chronic anemia is not covered by guidelines specific to older adults. When they consider that this treatment is necessary in elderly patients, French general practitioners (GPs) contact a hospital specialist to plan a transfusion. METHODS: Twenty French GPs were questioned individually regarding their approach to blood transfusion using semi-structured interviews. Each interview was recorded, typed up verbatim and then coded using an inductive procedure by theme, in a cross-over design (two researchers) in two phases: analysis and summary, followed by grouping of the recorded comments...
July 11, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28690038/-transfusion-in-elderly-take-account-frailty
#14
R Mahmoudi, J-L Novella, Y Jaïdi
The conjunction of the demographic aging and the increase in the frequency of anemia with the advancing age, mean that the number of globular concentrates delivered each year increases with a consequent heavy pressure on blood collection. The etiologies of anemia in the elderly are often multifactorial and their investigation is an indispensable step and prior to any treatment. Transfusion thresholds, particularly in the elderly, are gradually evolving and a so-called restrictive strategy is now favored. Immediate and delayed complications of transfusion are more frequent in the elderly due to vulnerability factors associated with frailty and the risk of multiple transfusions...
July 6, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28688079/self-perceived-care-needs-in-older-adults-with-joint-pain-and-comorbidity
#15
Lotte A H Hermsen, Emiel O Hoogendijk, Johannes C van der Wouden, Martin Smalbrugge, Stephanie S Leone, Henriëtte E van der Horst, Joost Dekker
BACKGROUND: The aim of this study was to explore self-perceived care needs and determinants of identified needs in older adults with joint pain and comorbidity. METHODS: This is a cross-sectional study using baseline data from a cohort study of older adults in the Netherlands (≥65 years) with joint pain and comorbidity (n = 407). We used the Camberwell Assessment of Need for the Elderly (CANE) to assess self-perceived care needs. Regression analyses were conducted to examine the associations between needs and sociodemographic factors (age, gender, partner status and educational level), physical factors (pain intensity, comorbidity, frailty and physical functioning) and psychosocial factors (anxiety, depression and social support)...
July 7, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28684438/five-year-follow-up-after-transcatheter-aortic-valve-implantation-for-symptomatic-aortic-stenosis
#16
Ralf Zahn, Nicolas Werner, Ulrich Gerckens, Axel Linke, Horst Sievert, Philipp Kahlert, Rainer Hambrecht, Stefan Sack, Mohamed Abdel-Wahab, Ellen Hoffmann, Uwe Zeymer, Steffen Schneider
OBJECTIVES: Transcatheter aortic valve implantation (TAVI) has been implemented into the care of elderly patients suffering from severe symptomatic aortic stenosis. However, data on long-term follow-up are sparse and predictors of long-term mortality need to be evaluated to better select patients. Therefore, we aimed to analyse predictors of 5-year mortality after TAVI. METHODS: We analysed data from the German Transcatheter Aortic Valve Interventions-Registry. Each of the 27 participating hospitals agreed to include all consecutive TAVI patients at their institution...
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28683406/crimes-against-the-elderly-in-italy-2007-2014
#17
Claudio Terranova, Greta Bevilacqua, Margherita Zen, Massimo Montisci
Crimes against the elderly have physical, psychological, and economic consequences. Approaches for mitigating them must be based on comprehensive knowledge of the phenomenon. This study analyses crimes against the elderly in Italy during the period 2007-2014 from an epidemiological viewpoint. Data on violent and non-violent crimes derived from the Italian Institute of Statistics were analysed in relation to trends, gender and age by linear regression, T-test, and calculation of the odds ratio with a 95% confidence interval...
June 27, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28675572/association-between-frailty-and-carotid-intima-media-thickness-and-inflammatory-marker-in-an-elderly-population
#18
Chun-Chin Chang, Chien-Yi Hsu, Po-Hsun Huang, Li-Kuo Liu, Liang-Kung Chen, Jaw-Wen Chen, Shing-Jong Lin
AIM: Frailty is a highly prevalent geriatric syndrome, characterized by increased vulnerability to subsequent morbidity and mortality. The association between frailty and preclinical atherosclerosis remains uncertain. The aim of the present study was to clarify the relationship between frailty, preclinical atherosclerosis and inflammatory markers in older adults. METHODS: We enrolled 1798 inhabitants of I-Lan County of Taiwan (855 men, 47.5%; mean age 64 ± 9 years, range 50-92 years)...
July 4, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28668143/prognosis-impact-of-frailty-assessed-by-the-edmonton-frail-scale-in-the-setting-of-acute-coronary-syndrome-in-the-elderly
#19
Stéphanie Blanco, Jean Ferrières, Vanina Bongard, Olivier Toulza, Fatia Sebai, Sophie Billet, Caroline Biendel, Olivier Lairez, Thibault Lhermusier, Nicolas Boudou, Francisco Campelo-Parada, Jérôme Roncalli, Michel Galinier, Didier Carrié, Meyer Elbaz, Frédéric Bouisset
BACKGROUND: Elderly patients represent a large proportion of patients admitted for acute coronary syndrome (ACS). Whether frailty-defined as a biological syndrome that reflects a state of decreased physiological reserve and vulnerability to stressors-may impact the clinical outcomes in this population remains unclear. We aimed to determine the prevalence of frailty and its impact on mortality in patients aged ≥ 80 years admitted for ACS. METHODS: This prospective observational study was conducted in patients aged 80 years or older admitted to a tertiary hospital for ACS...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28667436/comparison-of-quality-of-life-among-community-dwelling-older-adults-with-the-frailty-phenotype
#20
Sergio Sánchez-García, Katia Gallegos-Carrillo, María Claudia Espinel-Bermudez, Svetlana V Doubova, Rosalinda Sánchez-Arenas, Carmen García-Peña, Antoni Salvà, Silvia C Briseño-Fabian
PURPOSE: To compare the perception of the quality of life (QOL) of community-dwelling older adults with the phenotype of frailty. METHODS: Cross-sectional analysis of baseline data of the "Cohort of Obesity, Sarcopenia and Frailty of Mexican Older Adults" (COSFOMA). Operationalization of frailty was carried out using the phenotype as follows: weight loss, self-report of exhaustion, low physical activity, slow gait, and weakness. QOL was measured using two scales: World Health Organization Quality of Life of Older Adults (WHOQOL-OLD), which is a specific instrument for the elderly population, and Short Form-36 Health Survey (SF-36), a generic instrument to evaluate the QOL related to health...
June 30, 2017: Quality of Life Research
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