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Trifecta

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https://www.readbyqxmd.com/read/29153147/trifecta-of-light-chain-cast-nephropathy-monoclonal-plasma-cell-infiltrates-and-light-chain-proximal-tubulopathy
#1
Abhilash Koratala, A Ahsan Ejaz, Wesley M Hiser, William L Clapp
No abstract text is available yet for this article.
December 2017: Kidney International
https://www.readbyqxmd.com/read/29119598/opening-closing-pattern-of-trifecta-and-freestyle-valves-versus-native-aortic-valve-are-stentless-valves-more-physiologic-than-a-stented-valve
#2
Giordano Tasca, Riccardo Vismara, Francesco Trinca, Beatrice Riva, Amando Gamba, Elisabetta Lobiati
BACKGROUND: Stentless valves have long been considered the ideal valves in terms of hemodynamics. Recently, the Trifecta valve, a stented bioprosthesis with excellent fluid dynamic characteristics, has become available. The aim of the study was to compare the opening/closing pattern of the Freestyle stentless valve and the Trifecta valve with that of the native aortic valve. METHODS: A total of 12 patients with a Freestyle and 10 with a Trifecta valve were compared to normal native aortic valves in 12 control patients...
November 9, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29095979/rest-and-exercise-haemodynamics-in-patients-with-one-of-two-stented-bioprostheses-and-in-healthy-controls-with-small-aortic-annuli
#3
Sina Stock, Inga Lohmann, Thorsten Hanke, Ulrich Stierle, Doreen Richardt, Stanislav Tsvelodub, Hans-Hinrich Sievers
OBJECTIVES: Because bioprosthetic aortic valve replacement remains one of the most frequent cardiac surgical procedures, it is necessary to study patient haemodynamics in more detail. Until now, a few studies assessed haemodynamics during exercise, but none with special regard to small aortic annuli. We compared patients who had the differently designed bioprostheses, Trifecta and Perimount Magna Ease (PME), size ≤ 23 mm, and a healthy control group during rest and exercise. METHODS: We determined the mean transvalvular gradient, the effective orifice area (EOA) and the EOA index during rest and exercise using transthoracic echocardiography in 35 patients with the Trifecta (mean age 71...
October 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29080814/sleep-devices-wearables-and-nearables-informational-and-interventional-consumer-and-clinical
#4
Matt T Bianchi
The field of sleep is in many ways ideally positioned to take full advantage of advancements in technology and analytics that is fueling the mobile health movement. Combining hardware and software advances with increasingly available big datasets that contain scored data obtained under gold standard sleep laboratory conditions completes the trifecta of this perfect storm. This review highlights recent developments in consumer and clinical devices for sleep, emphasizing the need for validation at multiple levels, with the ultimate goal of using personalized data and advanced algorithms to provide actionable information that will improve sleep health...
October 25, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29074284/retroperitoneal-robot-assisted-versus-open-partial-nephrectomy-for-ct1-renal-tumors-a-matched-pair-comparison-of-perioperative-and-early-oncological-outcomes
#5
Marco Borghesi, Riccardo Schiavina, Francesco Chessa, Lorenzo Bianchi, Gaetano La Manna, Angelo Porreca, Eugenio Brunocilla
BACKGROUND: The objective of this study was to compare perioperative and early oncological outcomes of a matched cohort of patients who underwent retroperitoneal robot-assisted partial nephrectomy (RP-RAPN) and open partial nephrectomy (OPN) for clinically localized renal tumors. PATIENTS AND METHODS: We performed a retrospective analysis of patients who underwent RP-RAPN and OPN treated at 2 referral centers from January 2011 to December 2015. We focused on the following postoperative outcomes: warm ischemia time (WIT), operative time, blood loss, intra- and postoperative complications, estimated glomerular filtration rate (eGFR), hospital stay, and positive surgical margins...
October 3, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29048228/predictive-factors-for-achieving-superior-pentafecta-outcomes-following-robot-assisted-partial-nephrectomy-in-patients-with-localized-renal-cell-carcinoma
#6
Minyong Kang, In-Hyuck Gong, Hwi Jun Park, Hyun Hwan Sung, Hwang Gyun Jeon, Byong Chang Jeong, Seong Soo Jeon, Hyun Moo Lee, Han Yong Choi, Seong Il Seo
PURPOSE: To examine the perioperative outcomes following robot-assisted partial nephrectomy (RAPN) in patients with localized renal cell carcinoma (RCC) and to identify the predictors of Pentafecta achievement following RAPN. MATERIALS AND METHODS: We retrospectively analyzed the data from 362 patients with RCC who underwent RAPN from 2008 to 2016. The criteria for Pentafecta achievement was defined as the Trifecta [warm ischemia time (WIT) ≤ 25 minutes, negative surgical margin, and no significant perioperative complications]; with the addition of renal function preservation, including over 90% preservation of the estimated-glomerular filtration rate (e-GFR); and no stage upgrade of chronic kidney disease at 1 year after surgery...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29043611/quantifying-anthropogenic-threats-to-orchids-using-the-iucn-red-list
#7
Jenna Wraith, Catherine Pickering
Orchids are diverse, occur in a wide range of habitats and dominate threatened species lists, but which orchids are threatened, where and by what? Using the International Union for Conservation of Nature Red List, we assessed the range and diversity of threats to orchids globally including identifying four threat syndromes: (1) terrestrial orchids in forests that are endemic to a country and threatened by illegal collecting; (2) orchids threatened by climate change, pollution, transportation and disturbance/development for tourism, and recreation activities, often in East Asia; (3) epiphytic orchids in Sub-Saharan Africa including Madagascar with diverse threats; and (4) South and Southeast Asia orchids threatened by land clearing for shifting agriculture...
October 17, 2017: Ambio
https://www.readbyqxmd.com/read/28964416/the-prevalence-of-patient-prosthesis-mismatch-can-be-reduced-using-the-trifecta-aortic-prosthesis
#8
Daniel Hernandez-Vaquero, Rocio Diaz, Isaac Pascual, Jose Rozado, Jesus M De la Hera, Victor Leon, Pablo Avanzas, Maria Martín, Daniel García-Iglesias, David Calvo, Jacobo Silva, César Moris
BACKGROUND: Some important studies have shown that patient-prosthesis mismatch is a frequent occurrence after surgical aortic valve replacement that impairs survival. The Trifecta valve (St. Jude Medical Inc, St. Paul, MN) has special architecture designed to achieve the best hemodynamic profile. The aim of this study was to determine the prevalence of mismatch when using this prosthesis. METHODS: This study included 1,302 patients at 3 months postoperatively, 339 patients with a Trifecta prosthesis and 963 patients (the control group) with a Mitroflow aortic valve (Sorin Group Inc, Mitroflow Division, Vancouver, Canada)...
September 27, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28962508/replica-sizing-strategy-for-aortic-valve-replacement-improves-haemodynamic-outcome-of-the-epic-supra-valve
#9
David Gonzalez-Lopez, Gloria Faerber, Mahmoud Diab, Paulo Amorim, Natig Zeynalov, Torsten Doenst
OBJECTIVES: Current sizing strategies suggest valve selection based on annulus diameter despite supra-annular placement of biological prostheses potentially allowing placement of a larger size. We assessed the frequency of selecting a larger prosthesis if prosthesis size was selected using a replica (upsizing) and evaluated its impact on haemodynamics. METHODS: We analysed all discharge echocardiograms between June 2012 and June 2014, where a replica sizer was used for isolated aortic valve replacement (Epic Supra: 266 patients, Trifecta: 49 patients)...
October 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28951116/assessment-of-learning-curves-for-180-w-greenlight-xps-photoselective-vaporisation-of-the-prostate-a-multicentre-study
#10
Claire Bastard, Kevin Zorn, Benoit Peyronnet, Pierre Alain Hueber, Benjamin Pradère, Morgan Rouprêt, Vincent Misrai
BACKGROUND: The learning curve for photoselective vaporisation of the prostate (PVP) has never been assessed accurately. OBJECTIVE: To compare 180-W GreenLight XPS PVP learning curves for three surgeons with different levels of surgical experience and different institutional backgrounds. DESIGN, SETTING, AND PARTICIPANTS: A multicentre retrospective study of the first patients treated with PVP by three operators in three different centres (n=152 in group 1, n=112 in group 2, n=101 in group 3) was conducted...
September 23, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28927993/voltage-gated-sodium-channel-%C3%AE-subunits-the-power-outside-the-pore-in-brain-development-and-disease
#11
REVIEW
Jacob M Hull, Lori L Isom
Voltage gated sodium channels (VGSCs) were first identified in terms of their role in the upstroke of the action potential. The underlying proteins were later identified as saxitoxin and scorpion toxin receptors consisting of α and β subunits. We now know that VGSCs are heterotrimeric complexes consisting of a single pore forming α subunit joined by two β subunits; a noncovalently linked β1 or β3 and a covalently linked β2 or β4 subunit. VGSC α subunits contain all the machinery necessary for channel cell surface expression, ion conduction, voltage sensing, gating, and inactivation, in one central, polytopic, transmembrane protein...
September 18, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/28913771/criminal-prohibition-of-wrongful-re%C3%A2-identification-legal-solution-or-minefield-for-big-data
#12
Mark Phillips, Edward S Dove, Bartha M Knoppers
The collapse of confidence in anonymization (sometimes also known as de-identification) as a robust approach for preserving the privacy of personal data has incited an outpouring of new approaches that aim to fill the resulting trifecta of technical, organizational, and regulatory privacy gaps left in its wake. In the latter category, and in large part due to the growth of Big Data-driven biomedical research, falls a growing chorus of calls for criminal and penal offences to sanction wrongful re-identification of "anonymized" data...
September 14, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28895839/ocrevus-s-role-in-ms-battle-may-signal-promising-trend
#13
Thomas Morrow
With a list price that is 25% less than a competing drug, better outcomes, and less frequent dosing, maybe Ocrevus will start a new trend: better outcomes, easier administration-and a lower price. That trifecta is great news for people managing the cost and quality of MS care.
July 2017: Managed Care
https://www.readbyqxmd.com/read/28882030/outcomes-following-robotic-assisted-laparoscopic-prostatectomy-pentafecta-and-trifecta-achievements
#14
Seyed B Jazayeri, Brittany Weissman, David B Samadi
BACKGROUND: Functional and oncologic outcomes following radical prostatectomy play a major role in patient satisfaction after treatment. This study was designed to assess the functional and oncologic outcome after robotic assisted radical prostatectomy (RARP) in a single surgeon series of patients. METHODS: A prospectively maintained database of patients undergoing robotic radical prostatectomy in a referral academic center was queried for functional and oncologic outcome...
September 7, 2017: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/28865810/consolidated-state-political-party-control-and-the-enactment-of-obesity-related-policies-in-the-united-states
#15
Jennifer L Pomeranz, Arjumand Siddiqi, Gabriella J Bolanos, Jeremy A Shor, Rita Hamad
States play a key role in addressing obesity and its risk factors through policymaking, but there is variation in state activity nationally. The goal of this study was to examine whether the presence of a consolidated Democratic or Republican "trifecta" - when a state's governorship and both houses of the legislature are dominated by the same political party - or divided government (i.e., without a trifecta) is associated with obesity-related policy content and enactment. In 2016 and 2017, we gathered state bills and laws utilizing the CDC Chronic Disease State Policy Tracking System, and examined the association between state-level political party control and the enactment of state-level obesity-related policies in all states during 2009-2015...
December 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28749068/trifecta-outcomes-of-robot-assisted-partial-nephrectomy-in-solitary-kidney-a-vattikuti-collective-quality-initiative-vcqi-database-analysis
#16
Sohrab Arora, Ronney Abaza, James M Adshead, Rajesh K Ahlawat, Benjamin J Challacombe, Prokar Dasgupta, Giorgio Gandaglia, Daniel A Moon, T B Yuvaraja, Umberto Capitanio, Alessandro Larcher, Francesco Porpiglia, James R Porter, Alexander Mottrie, Mahendra Bhandari, Craig Rogers
OBJECTIVES: To analyze the outcomes of robot-assisted partial nephrectomy (RAPN) in patients with a solitary kidney in a large multi-institutional database. PATIENTS AND METHODS: A total of 2755 patients in the Vattikuti Collective Quality Initiative database underwent RAPN by 22 surgeons at 14 centers in nine 9 countries. Out of these patients, 74 underwent RAPN in solitary kidney between 2007 and 2016. A retrospective analysis of the functional and oncological outcomes was performed...
July 27, 2017: BJU International
https://www.readbyqxmd.com/read/28727369/comparison-of-two-different-suture-techniques-in-laparoscopic-partial-nephrectomy
#17
COMPARATIVE STUDY
Onur Kaygisiz, Sinan Çelen, Berna Aytac Vuruşkan, Hakan Vuruşkan
OBJECTIVE: To comparatively evaluate the traditional interrupted knot-tying and running suture renorrhaphy with Monocryl® in laparoscopic partial nephrectomy (LPN). MATERIALS AND METHODS: A retrospective analysis of 62 consecutive patients undergoing LPN using traditional interrupted knot-tying suture renorrhaphy (Group 1; n=31) or running suture technique renorrhaphy with 2-0 monofilament polyglecaprone (Monocryl®, Ethicon) (Group 2; n=31) from December 2011 to October 2015 at the University...
September 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28717275/initial-experience-of-robotic-nephron-sparing-surgery-in-cases-of-high-renal-nephrometry-scores
#18
Girdhar S Bora, Ravimohan S Mavuduru, Aditya P Sharma, Sudheer K Devana, Nandita Kakkar, Anupam Lal, Shrawan K Singh, Arup K Mandal
INTRODUCTION: The renal nephrometry scoring (RNS) system enables prediction the feasibility of nephron-sparing surgery (NSS) in renal masses. There is insufficient data regarding the outcome of robot-assisted NSS in tumors with RNS ≥10. We reviewed the trifecta outcomes of patients undergoing robotic NSS with high RNS and compare it with tumors of low and intermediate RNS. MATERIALS AND METHODS: Our prospectively maintained data of all robot-assisted NSS were reviewed, and those with RNS of ≥10 were identified...
July 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28698423/-early-structural-valve-deterioration-of-trifecta-biological-prosthesis-report-of-a-case
#19
Atsushi Tamura, Takamichi Yoshizaki, Sho Kusadokoro
Trifecta valve is a 3rd-generation, stented bioprosthesis which is made from one bovine pericardial sheet. A 77-years-old male patient had undergone combine aortic valve replacement (AVR) using a 23-mm Trifecta valve and ascending aorta replacement for severe aortic valve regurgitation and ascending aorta aneurysm. The postoperative period was uneventful. However, he presented with dyspnea on effort and severe aortic valve regurgitation 31 months after operation. Re-do AVR with a new bioprosthetic valve was performed via 2nd sternotomy...
July 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28689788/early-trifecta-valve-failure-warning-shot-or-unfair-scrutiny
#20
EDITORIAL
Robbin G Cohen
No abstract text is available yet for this article.
June 21, 2017: Journal of Thoracic and Cardiovascular Surgery
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