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lhx8a

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https://www.readbyqxmd.com/read/28151980/lhx8-interacts-with-a-novel-germ-cell-specific-nuclear-factor-containing-an-nbl1-domain-in-rainbow-trout-oncorhynchus-mykiss
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Liyuan Fu, Prasanthi P Koganti, Jian Wang, Lei Wang, Cheng-Lun Wang, Jianbo Yao
Lhx8 is an important transcription factor that is preferentially expressed in germ cells. Lhx8 null mice are infertile due to lack of oocytes and impairment of the transition from primordial follicles to primary follicles. Lhx8 deficiency also affects the expression of many important oocyte-specific genes. In this study, we report the characterization of rainbow trout lhx8 genes and identification of a novel germ cell-specific nuclear factor that interacts with Lhx8. Two lhx8 genes, lhx8a and lhx8b, were identified, encoding proteins of 344 and 361 amino acids, respectively...
2017: PloS One
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