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https://www.readbyqxmd.com/read/28544641/reflectance-spectroscopy-to-shed-new-light-on-the-capillary-refill-test
#1
Rani Toll John, Joakim Henricson, Gert E Nilsson, Daniel Wilhelms, Chris D Anderson
To use Bioengineering methodology is used to achieve, at five anatomical sites, a detailed, quantitative assessment of the return of blood content to the blanched area, during the Capillary Refill (CR) test. An observational, non-randomized, experimental study on 23 healthy subjects (14 females) was performed in our climate controlled skin physiology laboratory. Our main outcome measures were based on the chronological assessment and quantification of red blood cell concentration (RBC) after the release of blanching pressure in the CR test, using Tissue Viability Imaging (TiVi), a digital photographic technique based on polarisation spectroscopy...
May 24, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28540801/umbilical-temperature-correlation-with-core-and-skin-temperatures-at-rest-in-the-heat-and-during-physical-activity
#2
Raymond J Roberge, Jung-Hyun Kim, Patrick Yorio, Aitor Coca, Yongsuk Seo, Tyler Quinn, Ali Aljaroudi, Jeffrey B Powell
PURPOSE: to determine the correlation of umbilical temperatures (Tumb) with simultaneously recorded chest wall temperature (Tchest) and rectal temperature (Trectal) in adults during rest, heat exposure and exercise. METHODS: A total of 28 healthy men, wearing different types of clothing (athletic garb, a spandex full body heating garment, firefighter bunker gear) had average and peak umbilical, chest wall and rectal temperature measurements taken during sedentary temperature stabilisation stages, heat exposure periods and active exercise phases...
April 19, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540196/significance-of-platelet-count-in-children-admitted-with-bronchiolitis
#3
Amar Al Shibli, Najla Alkuwaiti, May Hamie, Dima Abukhater, Muhammad B Noureddin, Abdulla Amri, Salwa Al Kaabi, Aysha Al Kaabi, Mariam Harbi, Hassib Narchi
AIM: To determine the true prevalence of thrombocytosis in children less than 2 years of age with bronchiolitis, its association with risk factors, disease severity and thromboembolic complications. METHODS: A retrospective observational medical chart review of 305 infants aged two years or less hospitalized for bronchiolitis. Clinical outcomes included disease severity, duration of hospital stay, admission to pediatric intensive care unit, or death. They also included complications of thrombocytosis, including thromboembolic complications such as cerebrovascular accident, acute coronary syndrome, deep venous thrombosis, pulmonary embolus, mesenteric thrombosis and arterial thrombosis and also hemorrhagic complications such as bleeding (spontaneous hemorrhage in the skin, mucous membranes, gastrointestinal, respiratory, or genitourinary tracts)...
May 8, 2017: World Journal of Clinical Pediatrics
https://www.readbyqxmd.com/read/28539148/localized-heat-urticaria-from-95-ghz-millimeter-waves
#4
John A Gibbons
INTRODUCTION: Local heat urticaria is a physical urticaria caused by the environmental stimulus of heat. Typically, the resultant lesion, a wheal, is pruritic (itches) and is sometimes accompanied by a burning sensation. It is a self-limited phenomenon that resolves after 1.5-2 h. The prevalence of local heat urticaria in the general population has been estimated as 1 in 200,000 persons. CASE REPORT: The subject, a 39-yr-old active duty man, participated in a test of a 95-GHz energy beam designed to heat the skin...
June 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28538774/influence-of-the-ventilatory-mode-on-acute-adverse-effects-and-facial-thermography-after-noninvasive-ventilation
#5
Suzy Maria Montenegro Pontes, Luiz Henrique de Paula Melo, Nathalia Parente de Sousa Maia, Andrea da Nóbrega Cirino Nogueira, Thiago Brasileiro Vasconcelos, Eanes Delgado Barros Pereira, Vasco Pinheiro Diógenes Bastos, Marcelo Alcantara Holanda
Objective: To compare the incidence and intensity of acute adverse effects and the variation in the temperature of facial skin by thermography after the use of noninvasive ventilation (NIV). Methods: We included 20 healthy volunteers receiving NIV via oronasal mask for 1 h. The volunteers were randomly divided into two groups according to the ventilatory mode: bilevel positive airway pressure (BiPAP) or continuous positive airway pressure (CPAP). Facial thermography was performed in order to determine the temperature of the face where it was in contact with the mask and of the nasal dorsum at various time points...
March 2017: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/28536040/the-flir-one-thermal-imager-for-the-assessment-of-burn-wounds-reliability-and-validity-study
#6
M E H Jaspers, M E Carrière, A Meij-de Vries, J H G M Klaessens, P P M van Zuijlen
BACKGROUND: Objective measurement tools may be of great value to provide early and reliable burn wound assessment. Thermal imaging is an easy, accessible and objective technique, which measures skin temperature as an indicator of tissue perfusion. These thermal images might be helpful in the assessment of burn wounds. However, before implementation of a novel measurement tool into clinical practice is considered, it is appropriate to test its clinimetric properties (i.e. reliability and validity)...
May 20, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28536038/a-review-of-the-evidence-for-threshold-of-burn-injury
#7
REVIEW
N A Martin, S Falder
INTRODUCTION: Burn injury is common and depth is one measure of severity. Although the depth of burn injury is determined by many factors, the relationship between the temperature of the injurious agent and exposure duration, known as the time-temperature relationship, is widely accepted as one of the cornerstones of burn research. Moritz and Henriques first proposed this relationship in 1947 and their seminal work has been cited extensively. However, over the years, readers have misinterpreted their findings and incorporated misleading information about the time-temperature relationship into a wide range of industrial standards, burn prevention literature and medicolegal opinion...
May 20, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28532061/wound-healing-effect-of-bioactive-ion-released-from-mg-smectite
#8
Yu Sasaki, Gulsan Ara Sathi, Osamu Yamamoto
Bioactive ions like Mg(2+) and Si(4+) have been known as promotion factors of tissue regeneration. In the present work, Mg-smectite, consisting of Mg(2+) and Si(4+) ions, was synthesized by a solution process, and evaluated for the efficiency of the powder on wound healing in rats. White precipitates were obtained by mixing a magnesium chloride hexahydrate solution and a sodium silicate hexahydrate solution at room temperature. The precipitates mixed with a NaOH aqueous solution were subjected to hydrothermal reaction, and finally crystalline Mg-smectite powder was obtained...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28531316/a-comprehensive-method-to-quantify-adaptations-by-male-and-female-mice-with-hot-flashes-induced-by-the-neurokinin-b-receptor-agonist-senktide
#9
Ashley A Krull, Sarah A Larsen, Donald K Clifton, Genevieve Neal-Perry, Robert A Steiner
Vasomotor symptoms (VMS, or hot flashes) plague millions of reproductive age men and women who have natural or iatrogenic loss of sex steroid production. Many affected individuals are left without treatment options because of contraindications to hormone replacement therapy and the lack of equally effective non-hormonal alternatives. Moreover, development of safer, more effective therapies has been stymied by the lack of an animal model that recapitulates the hot flash phenomenon and enables direct testing of hypotheses regarding the pathophysiology underlying hot flashes...
May 22, 2017: Endocrinology
https://www.readbyqxmd.com/read/28528851/microstructure-evaluation-of-dermally-applicable-liquid-crystals-as-a-function-of-water-content-and-temperature-can-electron-paramagnetic-resonance-provide-complementary-data
#10
Mirjam Gosenca Matjaž, Janez Mravljak, Marija Bešter Rogač, Marjeta Šentjurc, Mirjana Gašperlin, Alenka Zvonar Pobirk
Insight into the microstructure of lyotropic liquid crystals (LCs) is of crucial importance for development of novel dermal delivery systems. Our aim was to evaluate the phase behaviour of dermally applicable LCs composed of isopropyl myristate/Tween 80/lecithin/water, along the dilution line, where phase transitions are predominantly driven by increased water content. Additionally, identification of LC temperature dependence is of great importance for skin application. Selected LCs were evaluated using electron paramagnetic resonance (EPR) plus conventionally used methods of polarization microscopy, small-angle X-ray scattering, differential scanning calorimetry, and rheological measurements...
May 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28528614/multifocal-tuberculosis-verrucosa-cutis-a-manifestation-extraordinary-of-reactivation-secondary-tuberculosis
#11
Virendra N Sehgal, Prashant Verma, Sambit N Bhattacharya, Sonal Sharma, Navjeevan Singh
A BCG (Bacillus Calmette-Guérin)-vaccinated 78-year-old man, a native Indian, reported with numerous asymptomatic, peanut-sized, dirty gray, elevated eruptions of 1 year's duration appearing over apparently normal skin on the upper and lower extremities (Figure 1). The onset of the eruptions had been sudden, but they had progressed slowly. A history of cough and/or expectoration, evening rise of temperature, night sweats, or loss of appetite and weight was denied.
2017: Skinmed
https://www.readbyqxmd.com/read/28528394/a-novel-dual-wavelength-laser-stimulator-to-elicit-transient-and-tonic-nociceptive-stimulation
#12
Xiaoxi Dong, Tianjun Liu, Han Wang, Jichun Yang, Zhuying Chen, Yong Hu, Yingxin Li
This study aimed to develop a new laser stimulator to elicit both transient and sustained heat stimulation with a dual-wavelength laser system as a tool for the investigation of both transient and tonic experimental models of pain. The laser stimulator used a 980-nm pulsed laser to generate transient heat stimulation and a 1940-nm continuous-wave (CW) laser to provide sustained heat stimulation. The laser with 980-nm wavelength can elicit transient pain with less thermal injury, while the 1940-nm CW laser can effectively stimulate both superficial and deep nociceptors to elicit tonic pain...
May 20, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28527719/involvement-of-serotonin-in-the-ventral-tegmental-area-in-thermoregulation-of-freely-moving-rats
#13
Takayuki Ishiwata, Hiroshi Hasegawa, Benjamin N Greenwood
We have recently reported that the serotonin (5-HT) projections from the midbrain's raphe nuclei that contains 5-HT cell bodies may play a role both in heat production and in heat loss. The purpose of the present study was to clarify the involvement of 5-HT in the ventral tegmental area (VTA), where 5-HT is suggested to participate in thermoregulation, using the combined methods of telemetry, microdialysis, and high performance liquid chromatography, with a special emphasis on regulation of the body temperature (Tb) in freely moving rats...
May 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28527126/polycaprolactone-based-nanoparticles-loaded-with-indomethacin-for-anti-inflammatory-therapy-from-preparation-to-ex-vivo-study
#14
Waisudin Badri, Karim Miladi, Sophie Robin, Céline Viennet, Qand Agha Nazari, Géraldine Agusti, Hatem Fessi, Abdelhamid Elaissari
PURPOSE: This work focused on the preparation of polycaprolactone based nanoparticles containing indomethacin to provide topical analgesic and anti-inflammatory effect for symptomatic treatment of inflammatory diseases. Indomethacin loaded nanoparticles are prepared for topical application to decrease indomethacin side effects and administration frequency. Oppositely to already reported works, in this research non-invasive method has been used for the enhancement of indomethacin dermal drug penetration...
May 19, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28526914/finite-element-method-simulating-temperature-distribution-in-skin-induced-by-980-nm-pulsed-laser-based-on-pain-stimulation
#15
Han Wang, Xiao-Xi Dong, Ji-Chun Yang, He Huang, Ying-Xin Li, Hai-Xia Zhang
For predicting the temperature distribution within skin tissue in 980-nm laser-evoked potentials (LEPs) experiments, a five-layer finite element model (FEM-5) was constructed based on Pennes bio-heat conduction equation and the Lambert-Beer law. The prediction results of the FEM-5 model were verified by ex vivo pig skin and in vivo rat experiments. Thirty ex vivo pig skin samples were used to verify the temperature distribution predicted by the model. The output energy of the laser was 1.8, 3, and 4.4 J. The laser spot radius was 1 mm...
May 19, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28526876/inductive-flash-annealing-of-bulk-metallic-glasses
#16
K Kosiba, S Pauly
We developed a temperature-controlled inductive flash-annealing device, which heats bulk metallic glasses (BMGs) at defined rates of up to 200 K/s to a given temperature. Subsequent instantaneous quenching in water allows preserving the microstructures obtained at various stages of crystallization. One Zr-based and two CuZr-based BMGs were flash-annealed at the onset of crystallization with different heating rates in order to prepare advanced BMG-matrix composites. The highly reproducible composite microstructures contain uniformly dispersed crystals and a narrow crystal size distribution...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28525631/primary-leiomyosarcoma-of-inferior-vena-cava-adjacent-to-hepatic-veins-complete-off-pump-resection-and-inferior-vena-cava-graft-reconstruction-with-application-of-external-skin-surface-cooling
#17
Michael Malyshev, Sergey Zotov, Anton Malyshev, Andrey Rostovykh
OBJECTIVES: Resection of a leiomyosarcoma of the inferior vena cava (IVC) requires venovenous bypass, especially if IVC clamping above the hepatic veins is planned. This report describes the application of external skin surface cooling for off-pump resection of a primary IVC leiomyosarcoma adjacent to the hepatic veins with graft IVC reconstruction in conditions of suprahepatic caval clamping and uninterrupted Pringle's manoeuvre. METHODS: A 62-year-old woman presented with IVC leiomyosarcoma adjacent to the hepatic veins...
May 19, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28522185/orofacial-complex-regional-pain-syndrome-pathophysiologic-mechanisms-and-functional-mri
#18
Yeon-Hee Lee, Kyung Mi Lee, Hyug-Gi Kim, Soo-Kyung Kang, Q-Schick Auh, Jyung-Pyo Hong, Yang-Hyun Chun
Complex regional pain syndrome (CRPS) is one of the most challenging chronic pain conditions and is characterized by burning pain, allodynia, hyperalgesia, autonomic changes, trophic changes, edema, and functional loss involving mainly the extremities. Until recently, very few reports have been published concerning CRPS involving the orofacial area. We report on a 50-year-old female patient who presented with unbearable pain in all of her teeth and hypersensitivity of the facial skin. She also reported intractable pain in both extremities accompanied by temperature changes and orofacial pain that increased when the other pains were aggravated...
March 14, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28518006/cooling-effects-of-wearer-controlled-vaporization-for-extravehicular-activity
#19
Kunihiko Tanaka, Daiki Nagao, Kosuke Okada, Koji Nakamura
INTRODUCTION: The extravehicular activity suit currently used by the United States in space includes a liquid cooling and ventilation garment (LCVG) that controls thermal conditions. Previously, we demonstrated that self-perspiration for evaporative cooling (SPEC) garment effectively lowers skin temperature without raising humidity in the garment. However, the cooling effect is delayed until a sufficient dose of water permeates and evaporates. In the present study, we hypothesized that wearer-controlled vaporization improves the cooling effect...
April 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28516802/the-influence-of-heating-on-toe-pressure-in-patients-with-peripheral-arterial-disease
#20
N Settembre, T Kagayama, P Kauhanen, P Vikatmaa, Y Inoue, M Venermo
BACKGROUND AND AIM: The toe skin temperature in vascular patients can be low, making reliable toe pressure measurements difficult to obtain. The aim of this study was to evaluate the effect of heating on the toe pressure measurements. MATERIALS AND METHODS: A total of 86 legs were examined. Brachial pressure and toe pressure were measured at rest in a supine position using a laser Doppler device that also measured skin temperature. After heating the toes for 5 min with a heating pad, we re-measured the toe pressure...
May 1, 2017: Scandinavian Journal of Surgery: SJS
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