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Amani F Abaza, Osama N Mohamed, Fathy K El-Fiky, Khaled A Ahmed
OBJECTIVES: This study aimed to determine the occurrence of methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage among patients, healthcare workers (HCWs), and community individuals, as well as to test the effect of tea extracts on detected S. aureus isolates. MATERIALS AND METHODS: This cross-sectional study that was followed by an experimental study included a total of 1021 nasal swab samples that were collected from 470 community cases, 191 HCWs, and 360 patients...
September 2016: Journal of the Egyptian Public Health Association
Mohamed Salah I Abaza, Mohammad Afzal, Raja'a J Al-Attiyah, Radhika Guleri
BACKGROUND: Natural products are valuable sources for anticancer agents. In the present study, methylferulate (MF) was identified for the first time from Tamarix aucheriana. Spectral data were used for identification of MF. The potential of MF to control cell growth, cell cycle, apoptosis, generation of reactive oxygen species (ROS), cancer cell invasion, nuclear factor kappa B (NFkB) DNA-binding activity and proteasomal activities, as well as the enhancement of chemosensitivity in human colorectal cancer cells, were evaluated...
October 1, 2016: BMC Complementary and Alternative Medicine
Nouran M Abaza, Reem M El-Mallah, Asmaa Shaaban, Sameh A Mobasher, Khaled F Al-Hassanein, Amr A Abdel Zaher, Rania H El-Kabarity
BACKGROUND: The emerging role of vitamin D in immunology and autoimmune disorders has been a worldwide interest in the last decade. Systemic lupus erythematosus (SLE) patients are particularly at a delicate position predisposing them to suffer from vitamin D deficiency due to the multiple risk factors accompanying the disease. Whether vitamin D deficiency is also involved as a risk factor for developing SLE and affecting its course is a considerable concern. OBJECTIVES: The objective of this study was to estimate the prevalence of vitamin D deficiency in SLE patients and its relation to disease...
2016: Integrative Medicine Insights
Violet Kasabri, Entisar K Al-Hallaq, Yasser K Bustanji, Khalid K Abdul-Razzak, Ismail F Abaza, Fatma U Afifi
CONTEXT: Adiantum capillus-veneris L. (Adiantaceae) hypocholesterolemic activity is therapeutically praised. OBJECTIVES: Pharmacological modulation of pancreatic triacylglycerol lipase (PL) and α-amylase/α-glucosidase by A. capillus-veneris are evaluated. MATERIALS AND METHODS: Using positive controls (acarbose, orlistat, guar gum, atorvastatin, glipizide and metformin) as appropriate, crude aqueous extracts (AEs) of A. capillus-veneris aerial parts were tested via a combination of in vitro enzymatic (0...
September 23, 2016: Pharmaceutical Biology
Fatima Z Husain, Daniel C Rosen, David J Paulucci, John P Sfakianos, Ronney Abaza, Ketan K Badani
OBJECTIVE: To assess the association between the R.E.N.A.L. Nephrometry score, the amount of non-neoplastic parenchymal volume (NNPV) removed, and the renal function decline in patients undergoing robotic partial nephrectomy (RPN). PATIENTS AND METHODS: The Multi-institutional Mount Sinai Kidney Cancer Database was used to identify 1235 patients who underwent RPN between January 2008 and February 2016, of whom 366 had complete data, including NNPV removed. Mann-Whitney U tests and univariable linear regression models were used to assess the relationships between R...
October 2016: Journal of Endourology
Daniel R Gilbert, Jordan Angell, Ronney Abaza
OBJECTIVE: To determine whether lymphoceles can be prevented after robotic prostatectomy with pelvic lymph node dissection (PLND), we performed a prospective randomized study using an absorbable hemostatic agent (Arista®AH). The most common complications of PLND for prostate cancer are related to lymphocele formation, which occur in 30-50% of patients according to studies that performed screening imaging. While most are asymptomatic, when intervention is required the cost and morbidity are high...
September 1, 2016: Urology
Kyle A Blum, David J Paulucci, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Joan C Delto, Louis S Krane, Ashok K Hemal, Ketan K Badani
OBJECTIVE: To compare renal function outcome between a contemporary cohort of propensity score-matched patients undergoing main renal artery clamping (MAC) alone and those undergoing main renal artery clamping with renal vein clamping (MVAC) during robotic partial nephrectomy. MATERIALS AND METHODS: Patients with a solitary T1 renal mass undergoing robotic partial nephrectomy were propensity score-matched on American Society of Anesthesiologists score, RENAL Nephrometry score, tumor size, tumor laterality, and operating surgeon to provide 66 patients undergoing MAC and 66 patients undergoing MVAC for analysis...
August 26, 2016: Urology
Charlotte Schramm, Annegret Abaza, Gunnar Blumenstock, Till E Bechtold, Annekatrin Rickmann, Karl-Ulrich Bartz-Schmidt, Dorothea Besch, Kai Januschowski
PURPOSE: A proof of principle study showed that the TheraMon(®) -microsensor can reliably measure wearing times of glasses and occlusion patches while having no discomfort for the bearer. The goal of this study was to identify specific temperature profiles in a larger patient group wearing the microsensor with an occlusion patch on the eye, the forehead or in the trouser pocket. METHODS: Temperature measurements with microsensors were performed at the orbital rim of the eye, at the forehead and in a trousers pocket of 20 healthy adults...
June 27, 2016: Acta Ophthalmologica
Ghada Masoud, Aleya Abbass, Amani Abaza, Walaa Hazzah
Swimming pools have been identified as posing some public health risks to users due to either bacterial or chemical contamination. As a result, maintaining good swimming pool water quality is an important issue in preventing health risks for bathers. This study aimed to evaluate the bacteriological quality of some swimming pools in Alexandria and to investigate the prevalence of Staphylococcus aureus (S. aureus) in water samples. A total of 120 water samples from 10 swimming pools were collected. Bacteriological analysis included heterotrophic plate count (HPC) using pour plate method; enumeration of total coliforms (TC), Escherichia coli (E...
July 2016: Environmental Monitoring and Assessment
Hassan Bassiouni, Hany Aly, Khaled Zaky, Nouran Abaza, Thomas Bardin
OBJECTIVE: To compare serum 25 OH vitamin D (25 (OH) D) levels between medial femoro-tibial knee osteoarthritis (OA) patients and controls, and to detect structural progression in patients with mild to moderate knee osteoarthritis in relation to baseline 25(OH) D levels in a one-year longitudinal prospective cohort study. METHODS: Thirty eight patients with medial femoro-tibial knee OA according to the ACR criteria and no knee malalignement, and 20 age, sex and BMI-matched pain free controls were included in the vitamin D study...
April 4, 2016: Current Rheumatology Reviews
Eva M Aagaard, Mona Abaza
No abstract text is available yet for this article.
January 28, 2016: New England Journal of Medicine
Colleen K Spees, Kelly J Kelleher, Ronney Abaza, Steven K Clinton
Li-Fraumeni Syndrome (LFS) is an autosomal dominant genetic disorder associated with mutations in the TP53 gene and characterized by a propensity to develop a variety of malignancies resulting in a shortened lifespan. We report a case of prostate cancer in a 50 year old male with LFS. Experimental studies suggest that TP53 mutations in prostate cancer are associated with therapeutic resistance to radiation, chemotherapy, and anti-androgens, implying that LFS men may experience more aggressive cancer biology with implications for therapeutic decisions...
March 2015: Urology Case Reports
Hajer Abaza, Aziz Ben Chaabene, Sataa Sallami, Hammouda Boussen, Khaled Rahal, Fethi Guemira
No abstract text is available yet for this article.
June 2015: La Tunisie Médicale
Ronney Abaza, Ahmad Shabsigh, Erik Castle, Mohamad Allaf, Jim C Hu, Craig Rogers, Mani Menon, Monish Aron, Chandru P Sundaram, Daniel Eun
PURPOSE: Since the first report of robotic management of renal tumors with inferior vena cava tumor thrombi, few additional cases have been reported in the literature. We report our combined experience with this procedure, to our knowledge the first multi-institutional and largest series reported to date. MATERIALS AND METHODS: A retrospective, multi-institutional review of robotic nephrectomy with inferior vena cava tumor thrombectomy was performed with institutional review board approval...
April 2016: Journal of Urology
Arij Ben Chaaben, Hajer Abaza, Hayet Douik, Leila Chaouch, Fayza Ayari, Nesrine Ouni, Tasnim Mamoghli, Dorra Ben Guezella, Rachida Mejri, Latifa Harzallah, Fethi Guemira
Cytochrome P450 2E1 (CYP2E1) is a detoxifying enzyme that belongs to the phase I metabolism of xenobiotics. This enzyme is encoded by a highly polymorphic gene whose common polymorphism corresponds to the substitution of cytosine (C) and thymine (T) at position -1019 (rs2031920). This polymorphism has been identified in several cancers including nasopharyngeal cancer (NPC). The study involved 124 patients with nasopharyngeal carcinoma, compared with 166 healthy controls. The presence or absence of the polymorphism is determined by PCR-RFLP...
December 2015: Bulletin du Cancer
H M H Abaza, M I Elmougy, H M A El Maraghy, H M Mahmoud
INTRODUCTION: Stanniocalcin1 (STC1) is a hormone that regulates cell growth and survival; this study aimed to evaluate the STC1 gene expression in patients with acute leukemia and assess its prognostic significance. METHODS: Seventy-six patients with acute leukemia were enrolled for determination of mRNA STC1 by real-time quantitative polymerase chain reaction at diagnosis and at day 28. RESULTS: Median STC1 gene expression was 16.2 and 4...
February 2016: International Journal of Laboratory Hematology
A Hegazy, M George, Z Kalo, S Abaza, Y M Abbas, M Atef
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
S Ragab, M Diaa, R Hassan, R Abou Shady, G El-Sisi, Z Kalo, S Abaza, M Shaheen, Y Abbas
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
René J Sotelo, Alexander Haese, Victor Machuca, Luis Medina, Luciano Nuñez, Flavio Santinelli, Andrés Hernandez, Ali Riza Kural, Alexander Mottrie, Camilo Giedelman, Mariano Mirandolino, Kenneth Palmer, Ronney Abaza, Reza Ghavamian, Arieh Shalhav, Alireza Moinzadeh, Vipul Patel, Michael Stifelman, Ingolf Tuerk, David Canes
BACKGROUND: The uptake of robotic surgery has led to changes in potential operative complications, as many surgeons learn minimally invasive surgery, and has allowed the documentation of such complications through the routine collection of intraoperative video. OBJECTIVE: We documented intraoperative complications from robot-assisted radical prostatectomy (RARP) with the aim of reporting the mechanisms, etiology, and necessary steps to avoid them. Our goal was to facilitate learning from these complications to improve patient care...
February 2016: European Urology
Giacomo Novara, Sabrina La Falce, Ronney Abaza, James Adshead, Rajesh Ahlawat, Nicolò Maria Buffi, Ben Challacombe, Prokar Dasgupta, Daniel A Moon, Dipen J Parekh, Francesco Porpiglia, Sudhir Rawal, Craig Rogers, Alessandro Volpe, Mahendra Bhandari, Alexander Mottrie
OBJECTIVE: To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. PATIENTS AND METHODS: We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database...
April 2016: BJU International
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