keyword
MENU ▼
Read by QxMD icon Read
search

Circadian cognition

keyword
https://www.readbyqxmd.com/read/29138588/rai1-gene-mutations-mechanisms-of-smith-magenis-syndrome
#1
REVIEW
Mariateresa Falco, Sonia Amabile, Fabio Acquaviva
Smith-Magenis syndrome (SMS; OMIM #182290) is a complex genetic disorder characterized by distinctive physical features, developmental delay, cognitive impairment, and a typical behavioral phenotype. SMS is caused by interstitial 17p11.2 deletions, encompassing multiple genes and including the retinoic acid-induced 1 gene (RAI1), or by mutations in RAI1 itself. About 10% of all the SMS patients, in fact, carry an RAI1 mutation responsible for the phenotype. RAI1 (OMIM *607642) is a dosage-sensitive gene expressed in many tissues and highly conserved among species...
2017: Application of Clinical Genetics
https://www.readbyqxmd.com/read/29132973/mutual-influence-of-sleep-and-circadian-clocks-on-physiology-and-cognition
#2
REVIEW
Isabel Heyde, Jana-Thabea Kiehn, Henrik Oster
The 24-hour sleep-wake cycle is one of the most prominent outputs of the circadian clock system. At the same time, changes in sleep-wake behavior feedback on behavioral and physiological circadian rhythms, thus altering the coordination of the body's clock network. Sleep and circadian rhythm disruption have similar physiological endpoints including metabolic, cognitive, and immunologic impairments. This raises the question to which extent these phenomena are causally linked. In this review, we summarize different physiologic outcomes of sleep deprivation and mistimed sleep and discuss the experimental evidence for a mediating role of the circadian clock machinery in this context...
November 10, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29129126/chronic-circadian-misalignment-without-circadian-arrhythmicity-or-sleep-deprivation-does-not-impair-adult-hippocampal-neurogenesis
#3
Phan Q Duy, Samer Hattar
Artificial light in modern society has led to the ubiquity of light exposure at night as individuals work night shifts and use light-emitting electronic devices before bedtime. These aberrant light conditions have detrimental consequences on cognitive and mental health, compelling the need to understand the mechanisms by which light affects brain functions. Although it was believed that aberrant light impairs health by first disrupting circadian rhythms and sleep, we showed that chronic exposure to a light cycle termed T7 (3...
November 1, 2017: Journal of Biological Rhythms
https://www.readbyqxmd.com/read/29128778/circadian-blood-pressure-patterns-and-blood-pressure-control-in-patients-with-chronic-kidney-disease
#4
Nicola Di Daniele, Danilo Alunni Fegatelli, Valentina Rovella, Veronica Castagnola, Marco Gabriele, Angelo Scuteri
BACKGROUND AND AIMS: Hypertension is a major risk factor for chronic kidney disease (CKD), and CKD progression is associated with suboptimal blood pressure (BP) control. Here we evaluate the impact of CKD on the attainment of BP control and the circadian BP profile in older subjects. METHODS: In this observational study, we studied 547 patients referred to the hypertension clinic, of whom 224 (40.9%) had CKD. Blood pressure (BP) control and circadian BP patterns were evaluated by 24-hour ambulatory BP monitoring...
October 26, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29126762/association-between-abnormal-nocturnal-blood-pressure-profile-and-dementia-in-parkinson-s-disease
#5
Ryota Tanaka, Yasushi Shimo, Kazuo Yamashiro, Takashi Ogawa, Kenya Nishioka, Genko Oyama, Atsushi Umemura, Nobutaka Hattori
BACKGROUND: Circadian blood pressure alterations are frequently observed in Parkinson's disease, but the association between these changes and dementia in the condition remains unclear. Here, we assess the relationship between abnormal nocturnal blood pressure profiles and dementia in Parkinson's disease. METHODS: We enrolled 137 patients with Parkinson's disease, who underwent 24 h ambulatory blood pressure monitoring, following cognitive and clinical assessment...
October 20, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29126328/repeated-administration-effects-on-psychomotor-vigilance-test-pvt-performance
#6
Mathias Basner, Emanuel Hermosillo, Jad Nasrini, Sarah McGuire, Salil Saxena, Tyler M Moore, Ruben C Gur, David F Dinges
Study Objectives: The Psychomotor Vigilance Test (PVT) is reported to be free of practice effects that can otherwise confound the effects of sleep loss and circadian misalignment on performance. This differentiates the PVT from more complex cognitive tests. To our knowledge, no study has systematically investigated practice effects on the PVT across multiple outcome domains, depending on administration interval, and in ecologically more valid settings. Methods: We administered a validated 3-minute PVT (PVT-B) 16 times in 45 subjects (23 male, mean±SD age 32...
November 8, 2017: Sleep
https://www.readbyqxmd.com/read/29111783/would-you-say-yes-in-the-evening-time-of-day-effect-on-response-bias-in-four-types-of-working-memory-recognition-tasks
#7
Koryna Lewandowska, Barbara Wachowicz, Tadeusz Marek, Halszka Oginska, Magdalena Fafrowicz
Across a wide range of tasks, cognitive functioning is affected by circadian fluctuations. In this study, we investigated diurnal variations of working memory performance, taking into account not only hits and errors rates, but also sensitivity (d') and response bias (c) indexes (established by signal detection theory). Fifty-two healthy volunteers performed four experimental tasks twice - in the morning and in the evening (approximately 1 and 10 h after awakening). All tasks were based on Deese-Roediger-McDermott paradigm version dedicated to study working/short-term memory distortions...
November 7, 2017: Chronobiology International
https://www.readbyqxmd.com/read/29111422/shorter-sleep-duration-and-longer-sleep-onset-latency-are-related-to-difficulty-disengaging-attention-from-negative-emotional-images-in-individuals-with-elevated-transdiagnostic-repetitive-negative-thinking
#8
Jacob A Nota, Meredith E Coles
BACKGROUND AND OBJECTIVES: Repetitive negative thinking (RNT) is often associated with disruptions in sleep and circadian rhythms. Disruptions in sleep and circadian rhythms may deal a "second hit" to attentional control deficits. This study evaluated whether sleep and circadian rhythm disruptions are related to the top-down control of attention to negative stimuli in individuals with heightened repetitive negative thinking. METHODS: Fifty-two community adults with high levels of transdiagnostic RNT and varying habitual sleep durations and bedtimes participated in a hybrid free-viewing and directed attention task using pairs of emotionally-evocative and neutral images while eye-tracking data were collected...
October 19, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29108526/stabilising-sleep-for-patients-admitted-at-acute-crisis-to-a-psychiatric-hospital-owls-an-assessor-blind-pilot-randomised-controlled-trial
#9
Bryony Sheaves, Daniel Freeman, Louise Isham, Josephine McInerney, Alecia Nickless, Ly-Mee Yu, Stephanie Rek, Jonathan Bradley, Sarah Reeve, Caroline Attard, Colin A Espie, Russell Foster, Anna Wirz-Justice, Eleanor Chadwick, Alvaro Barrera
BACKGROUND: When patients are admitted onto psychiatric wards, sleep problems are highly prevalent. We carried out the first trial testing a psychological sleep treatment at acute admission (Oxford Ward sLeep Solution, OWLS). METHODS: This assessor-blind parallel-group pilot trial randomised patients to receive sleep treatment at acute crisis [STAC, plus standard care (SC)], or SC alone (1 : 1). STAC included cognitive-behavioural therapy (CBT) for insomnia, sleep monitoring and light/dark exposure for circadian entrainment, delivered over 2 weeks...
November 7, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29106402/selective-neuronal-lapses-precede-human-cognitive-lapses-following-sleep-deprivation
#10
Yuval Nir, Thomas Andrillon, Amit Marmelshtein, Nanthia Suthana, Chiara Cirelli, Giulio Tononi, Itzhak Fried
Sleep deprivation is a major source of morbidity with widespread health effects, including increased risk of hypertension, diabetes, obesity, heart attack, and stroke. Moreover, sleep deprivation brings about vehicle accidents and medical errors and is therefore an urgent topic of investigation. During sleep deprivation, homeostatic and circadian processes interact to build up sleep pressure, which results in slow behavioral performance (cognitive lapses) typically attributed to attentional thalamic and frontoparietal circuits, but the underlying mechanisms remain unclear...
November 6, 2017: Nature Medicine
https://www.readbyqxmd.com/read/29102282/sleep-and-alzheimer-s-disease-a-pivotal-role-for-the-suprachiasmatic-nucleus
#11
REVIEW
Jan Van Erum, Debby Van Dam, Peter Paul De Deyn
Alzheimer's disease (AD), which accounts for most of the dementia cases, is, aside from cognitive deterioration, often characterized by the presence of non-cognitive symptoms. Society is desperately in need for interventions that alleviate the economic and social burden related to AD. Circadian dysrhythmia, one of these symptoms in particular, immensely decreases the self-care ability of AD patients and is one of the main reasons of caregiver exhaustion. Studies suggest that these circadian disturbances form the root of sleep-wake problems, diagnosed in more than half of AD patients...
July 28, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/29097698/circadian-preference-towards-morningness-is-associated-with-lower-slow-sleep-spindle-amplitude-and-intensity-in-adolescents
#12
Ilona Merikanto, Liisa Kuula, Tommi Makkonen, Róbert Bódizs, Risto Halonen, Kati Heinonen, Jari Lahti, Katri Räikkönen, Anu-Katriina Pesonen
Individual circadian preference types and sleep EEG patterns related to spindle characteristics, have both been associated with similar cognitive and mental health phenotypes. However, no previous study has examined whether sleep spindles would differ by circadian preference. Here, we explore if spindle amplitude, density, duration or intensity differ by circadian preference and whether these associations are moderated by spindle location, frequency, and time distribution across the night. The participants (N = 170, 59% girls; mean age = 16...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29097017/emerging-roles-of-creb-regulated-transcription-coactivators-in-brain-physiology-and-pathology
#13
REVIEW
Carlos A Saura, Jean-René Cardinaux
The brain has the ability to sense, coordinate, and respond to environmental changes through biological processes involving activity-dependent gene expression. cAMP-response element binding protein (CREB)-regulated transcription coactivators (CRTCs) have recently emerged as novel transcriptional regulators of essential biological functions, while their deregulation is linked to age-related human diseases. In the brain, CRTCs are unique signaling factors that act as sensors and integrators of hormonal, metabolic, and neural signals contributing to brain plasticity and brain-body communication...
October 30, 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/29081329/treating-sleep-problems-in-young-people-at-ultra-high-risk-of-psychosis-a-feasibility-case-series
#14
Jonathan Bradley, Daniel Freeman, Eleanor Chadwick, Allison G Harvey, Bradley Mullins, Louise Johns, Bryony Sheaves, Belinda Lennox, Matthew Broome, Felicity Waite
BACKGROUND: Our view is that sleep disturbance may be a contributory causal factor in the development and maintenance of psychotic experiences. A recent series of randomized controlled intervention studies has shown that cognitive-behavioural approaches can improve sleep in people with psychotic experiences. However, the effects of psychological intervention for improving sleep have not been evaluated in young people at ultra-high risk of psychosis. Improving sleep might prevent later transition to a mental health disorder...
October 30, 2017: Behavioural and Cognitive Psychotherapy
https://www.readbyqxmd.com/read/29073187/sleep-and-cognitive-performance-of-african-americans-and-european-americans-before-and-during-circadian-misalignment-produced-by-an-abrupt-9-h-delay-in-the-sleep-wake-schedule
#15
Gemma M Paech, Stephanie J Crowley, Charmane I Eastman
We conducted two studies of circadian misalignment in non-Hispanic African and European-Americans. In the first, the sleep/wake (light/dark) schedule was advanced 9 h, similar to flying east, and in the second these schedules were delayed 9 h, similar to flying west or sleeping during the day after night work. We confirmed that the free-running circadian period is shorter in African-Americans compared to European-Americans, and found differences in the magnitude and direction of circadian rhythm phase shifts which were related to the circadian period...
2017: PloS One
https://www.readbyqxmd.com/read/29071701/-the-hypothalamus-in-huntington-s-disease
#16
REVIEW
E Bellosta-Diago, A Viloria-Alebesque, S Santos-Lasaosa, L J Lopez Del Val
INTRODUCTION: Disorders affecting sleep and the circadian rhythm, autonomic clinical signs and symptoms, and neuroendocrine alterations are frequent characteristics in Huntington's disease, some of which present in early stages of the disease. It is reasonable to think that some of these features could result from a hypothalamic dysfunction affecting the centre regulating sleep, metabolism and the autonomic nervous system. AIM: The study presents the evidence available to date that suggests the involvement of a hypothalamic disorder in Huntington's disease...
November 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/29059251/advancing-the-sleep-wake-schedule-impacts-the-sleep-of-african-americans-more-than-european-americans
#17
Gemma M Paech, Stephanie J Crowley, Louis F Fogg, Charmane I Eastman
There are differences in sleep duration between Blacks/African-Americans and Whites/European-Americans. Recently, we found differences between these ancestry groups in the circadian system, such as circadian period and the magnitude of phase shifts. Here we document the role of ancestry on sleep and cognitive performance before and after a 9-h advance in the sleep/wake schedule similar to flying east or having a large advance in sleep times due to shiftwork, both of which produce extreme circadian misalignment...
2017: PloS One
https://www.readbyqxmd.com/read/29046483/deficiency-of-shank2-causes-mania-like-behavior-that-responds-to-mood-stabilizers
#18
Andrea L Pappas, Alexandra L Bey, Xiaoming Wang, Mark Rossi, Yong Ho Kim, Haidun Yan, Fiona Porkka, Lara J Duffney, Samantha M Phillips, Xinyu Cao, Jin-Dong Ding, Ramona M Rodriguiz, Henry H Yin, Richard J Weinberg, Ru-Rong Ji, William C Wetsel, Yong-Hui Jiang
Genetic defects in the synaptic scaffolding protein gene, SHANK2, are linked to a variety of neuropsychiatric disorders, including autism spectrum disorders, schizophrenia, intellectual disability, and bipolar disorder, but the molecular mechanisms underlying the pleotropic effects of SHANK2 mutations are poorly understood. We generated and characterized a line of Shank2 mutant mice by deleting exon 24 (Δe24). Shank2Δe24-/- mice engage in significantly increased locomotor activity, display abnormal reward-seeking behavior, are anhedonic, have perturbations in circadian rhythms, and show deficits in social and cognitive behaviors...
October 19, 2017: JCI Insight
https://www.readbyqxmd.com/read/29027157/animal-models-for-bipolar-disorder-from-bedside-to-the-cage
#19
REVIEW
Dominik K E Beyer, Nadja Freund
Bipolar disorder is characterized by recurrent manic and depressive episodes. Patients suffering from this disorder experience dramatic mood swings with a wide variety of typical behavioral facets, affecting overall activity, energy, sexual behavior, sense of self, self-esteem, circadian rhythm, cognition, and increased risk for suicide. Effective treatment options are limited and diagnosis can be complicated. To overcome these obstacles, a better understanding of the neurobiology underlying bipolar disorder is needed...
October 13, 2017: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/28993753/electroencephalography-in-the-diagnosis-of-genetic-generalized-epilepsy-syndromes
#20
REVIEW
Udaya Seneviratne, Mark J Cook, Wendyl Jude D'Souza
Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized spike-wave complex. Other classic EEG abnormalities are polyspikes, epileptiform K-complexes and sleep spindles, polyspike-wave discharges, occipital intermittent rhythmic delta activity, eye-closure sensitivity, fixation-off sensitivity, and photoparoxysmal response...
2017: Frontiers in Neurology
keyword
keyword
62850
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"