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https://www.readbyqxmd.com/read/29332197/identification-as-a-mutation-carrier-and-effects-on-life-according-to-experiences-of-finnish-male-brca1-2-mutation-carriers
#1
Outi Kajula, Outi Kuismin, Helvi Kyngäs
Earlier studies have explored post-identification experiences of male BRCA1/2 mutation carriers, but more detailed knowledge of both their experiences and effects of identification as a carrier on their lives is required to improve genetic counseling. Thus, the aim of this study was to acquire deeper and broader insights into their experiences. Qualitative data were collected from theme-based interviews with 31 men carrying BRCA1/2 mutations in Finland, and analyzed using inductive content analysis. Three categories of the participants' responses to identification as BRCA1/2 mutation carriers were identified (personal, offspring-related and related to other relatives), mainly concerning issues associated with cancer, hereditary transmission of their mutations, and life decisions...
January 13, 2018: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/29330835/international-guidelines-for-groin-hernia-management
#2
(no author information available yet)
INTRODUCTION: Worldwide, more than 20 million patients undergo groin hernia repair annually. The many different approaches, treatment indications and a significant array of techniques for groin hernia repair warrant guidelines to standardize care, minimize complications, and improve results. The main goal of these guidelines is to improve patient outcomes, specifically to decrease recurrence rates and reduce chronic pain, the most frequent problems following groin hernia repair. They have been endorsed by all five continental hernia societies, the International Endo Hernia Society and the European Association for Endoscopic Surgery...
January 12, 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29328050/threshold-driven-optimization-for-reference-based-auto-planning
#3
Troy Long, Mingli Chen, Steve B Jiang, Weiguo Lu
We study threshold-driven optimization methodology for automatically generating a treatment plan that is motivated by a reference DVH for IMRT treatment planning. We present a framework for threshold-driven optimization for reference-based auto-planning (TORA). Commonly used voxel-based quadratic penalties have two components for penalizing under- and over-dosing of voxels: a reference dose threshold and associated penalty weight. Conventional manual- and auto-planning using such a function involves iteratively updating the preference weights while keeping the thresholds constant, an unintuitive and often inconsistent method for planning toward some reference DVH...
January 12, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29326186/factors-associated-with-neonatal-pneumonia-in-india-protocol-for-a-systematic-review-and-planned-meta-analysis
#4
Sreekumaran Nair, Leslie Edward Lewis, Myron Anthony Godinho, Shruti Murthy, Theophilus Lakiang, Bhumika T Venkatesh
INTRODUCTION: India accounts for more neonatal deaths than any other country. There is a lack of consolidated evidence from India regarding the determining factors of pneumonia in neonates. This systematic review is aimed to consolidate and appraise the evidence on risk factors and determinants of pneumonia among neonates in India. METHODS AND ANALYSIS: This protocol is part of a project consisting of three reviews (two systematic reviews and one scoping review) and a qualitative study on neonatal pneumonia in India...
January 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29325025/towards-an-understanding-of-resilience-responding-to-health-systems-shocks
#5
Johanna Hanefeld, Susannah Mayhew, Helena Legido-Quigley, Frederick Martineau, Marina Karanikolos, Karl Blanchet, Marco Liverani, Esther Yei Mokuwa, Gillian McKay, Dina Balabanova
The recent outbreak of Ebola Virus Disease (EVD) in West Africa has drawn attention to the role and responsiveness of health systems in the face of shock. It brought into sharp focus the idea that health systems need not only to be stronger but also more 'resilient'. In this article, we argue that responding to shocks is an important aspect of resilience, examining the health system behaviour in the face of four types of contemporary shocks: the financial crisis in Europe from 2008 onwards; climate change disasters; the EVD outbreak in West Africa 2013-16; and the recent refugee and migration crisis in Europe...
January 9, 2018: Health Policy and Planning
https://www.readbyqxmd.com/read/29324563/nutritional-screening-assessment-and-implementation-strategies-for-adults-in-an-australian-acute-tertiary-hospital-a-best-practice-implementation-report
#6
Louise Smith, Amanda Chapman, Kelli Flowers, Kylie Wright, Tanghua Chen, Charmaine O'Connor, Cecilia Astorga, Nevenka Francis, Gia Vigh, Craig Wainwright
OBJECTIVE: The project aimed to improve the effectiveness of nutritional screening and assessment practices through clinical audits and the implementation of evidence-based practice recommendations. INTRODUCTION: In the absence of optimal nutrition, health may decline and potentially manifest as adverse health outcomes. In a hospitalized person, poor nutrition may adversely impact on the person's outcome. If the nutritional status can be ascertained, nutritional needs can be addressed and potential risks minimized...
January 2018: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/29323865/building-capacity-through-urban-agriculture-report-on-the-ask%C3%A3-y-project
#7
Wanda Martin, Lindsey Vold
INTRODUCTION: Many North American cities have a built environment that provides access to energy-dense food and little opportunity for active living. Urban agriculture contributes to a positive environment involving food plant cultivation that includes processing, storing, distributing and composting. It is a means to increase local food production and thereby improve community health. The purpose of this study was to understand how participating in urban agriculture can help to empower young adults and build capacity for growing food in the city...
January 2018: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29320998/the-perceptions-and-experiences-of-women-who-achieved-and-did-not-achieve-a-waterbirth
#8
Lucy Lewis, Yvonne L Hauck, Caroline Crichton, Courtney Barnes, Corrinne Poletti, Helen Overing, Louise Keyes, Brooke Thomson
BACKGROUND: There is a gap in knowledge and understanding relating to the experiences of women exposed to the opportunity of waterbirth. Our aim was to explore the perceptions and experiences of women who achieved or did not achieve their planned waterbirth. METHODS: An exploratory design using critical incident techniques was conducted between December 2015 and July 2016, in the birth centre of the tertiary public maternity hospital in Western Australia. Women were telephoned 6 weeks post birth...
January 10, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29318824/-design-and-implementation-of-data-checking-system-for-chinese-materia-medica-resources-survey
#9
Hui Wang, Xiao-Bo Zhang, Xiao-Guang Ge, Yan Jin, Zhi-Xian Jing, Yuan-Hua Qi, Ling Wang, Yu-Ping Zhao, Wei Wang, Lan-Ping Guo, Lu-Qi Huang
The Chinese material medica resources (CMMR) national survey information management system has collected a large amount of data. To help dealing with data recheck, reduce the work of inside, improve the recheck of survey data from provincial and county level, National Resource Center for Chinese Materia Medical has designed a data checking system for Chinese material medica resources survey based on J2EE technology, Java language, Oracle data base in accordance with the SOA framework. It includes single data check, check score, content manage, check the survey data census data with manual checking and automatic checking about census implementation plan, key research information, general survey information, cultivation of medicinal materials information, germplasm resources information the medicine information, market research information, traditional knowledge information, specimen information of this 9 aspects 20 class 175 indicators in two aspects of the quantity and quality...
November 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29317383/research-and-practice-based-nutrition-education-and-cooking-workshops-in-pediatric-oncology-protocol-for-implementation-and-development-of-curriculum
#10
Cynthia Chaput, Sabrina Beaulieu-Gagnon, Véronique Bélanger, Simon Drouin, Laurence Bertout, Lucie Lafrance, Cinthia Olivier, Marthe Robitaille, Caroline Laverdière, Daniel Sinnett, Marie Marquis, Valérie Marcil
BACKGROUND: Progresses in childhood cancer treatment, diagnosis, and management have resulted in childhood cancer survival rates of over 80%. However, this therapeutic success comes with a heavy price: two-thirds of childhood cancer survivors will be affected by further complications, including cardiovascular and metabolic diseases. Adequate nutrition during cancer treatment is essential to ensure the child's optimal development, improve tolerance to treatments, and can contribute to lower the risk of developing cardiometabolic diseases...
January 9, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29316774/how-to-optimize-aesthetic-outcomes-in-implant-based-breast-reconstruction
#11
Maurizio Bruno Nava, Giuseppe Catanuto, Nicola Rocco
The evolution of breast reconstructive surgery keeps pace with the evolution of breast oncologic surgery. The reconstructive choice should always balance the optimal local control of disease and the best cosmetic result, reflecting an informed decision that is shared with the patient, who is always at the center of the decision-making process. Implant-based breast reconstruction following mastectomy represents a complex choice. In order to obtain optimal results, the following considerations are mandatory: thorough preoperative planning, a complete knowledge of the devices that are used, accurately performed surgery, and appropriate follow-up...
January 10, 2018: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29314746/integrative-review-of-the-intersection-of-green-space-and-neighborhood-violence
#12
Gibran C Mancus, Jacquelyn Campbell
PURPOSE: To systematically analyze evidence about the impact of green space on the perception and actual safety of residents of urban neighborhoods. DESIGN AND ORGANIZING CONSTRUCT: Systematic review of green space and violence based on Broome review criteria. METHODS: One landmark study prompted the initial hand search and identification of search terms. Twenty-three quantitative, five qualitative, and two mixed-methods studies were found in the urban planning, public health, medical, and psychological literature that met the following criteria: analyzed green space and violence as factors in the perception of safety as an outcome measure, including action taken by being outside for recreation, exercise, or self-report in the survey...
January 4, 2018: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29314480/preliminary-assessment-of-the-computer-based-taenia-solium-educational-program-the-vicious-worm-on-knowledge-uptake-in-primary-school-students-in-rural-areas-in-eastern-zambia
#13
Emma C Hobbs, Kabemba Evans Mwape, Inge Van Damme, Dirk Berkvens, Gideon Zulu, Moses Mambwe, Mwelwa Chembensofu, Isaac Khozozo Phiri, Maxwell Masuku, Emmanuel Bottieau, Brecht Devleesschauwer, Niko Speybroeck, Angela Colston, Pierre Dorny, Arve Lee Willingham, Sarah Gabriël
OBJECTIVE: The zoonotic helminth Taenia solium is endemic in Zambia, causing human (taeniasis and (neuro)cysticercosis) and pig (porcine cysticercosis) diseases with high health, social and economic burdens. We aimed to evaluate the impact of a health educational program intended to lead to powerful and cumulative improvements in knowledge, attitudes and practices that decrease parasite transmission and disease occurrence. METHODS: Half-day health education workshops were conducted in three primary schools in the highly endemic Eastern Province of Zambia, using the computer-based T...
January 4, 2018: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29310629/the-canadian-urban-environmental-health-research-consortium-a-protocol-for-building-a-national-environmental-exposure-data-platform-for-integrated-analyses-of-urban-form-and-health
#14
Jeffrey R Brook, Eleanor M Setton, Evan Seed, Mahdi Shooshtari, Dany Doiron
BACKGROUND: Multiple external environmental exposures related to residential location and urban form including, air pollutants, noise, greenness, and walkability have been linked to health impacts or benefits. The Canadian Urban Environmental Health Research Consortium (CANUE) was established to facilitate the linkage of extensive geospatial exposure data to existing Canadian cohorts and administrative health data holdings. We hypothesize that this linkage will enable investigators to test a variety of their own hypotheses related to the interdependent associations of built environment features with diverse health outcomes encompassed by the cohorts and administrative data...
January 8, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29302532/does-being-under-treatment-improve-knowledge-attitude-practice-for-hypertension-a-hospital-based-study-from-north-india
#15
Rajiv Kumar Gupta, Shahid Hussain, Zahida Parveen, Sunil Kumar Raina, Bhavna Langer, Rashmi Kumari
Background: Studies suggest that approximately half of patients with raised blood pressure (BP) are undetected, that half of those detected are not treated, and that half of those treated are not controlled, famously described as the "rule of halves." Importantly, the cornerstone of the primary prevention of cardiovascular diseases is early detection and drug treatment (antihypertensive) of patients with high BP. Studies across populations in developed world have shown that awareness and management of high BP levels are far from optimal...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29301593/artificial-intelligent-platform-as-decision-tool-for-asset-management-operations-and-maintenance
#16
(no author information available yet)
An Artificial Intelligence (AI) system has been developed and implemented for water, wastewater and reuse plants to improve management of sensors, short and long term maintenance plans, asset and investment management plans. It is based on an integrated approach to capture data from different computer systems and files. It adds a layer of intelligence to the data. It serves as a repository of key current and future operations and maintenance conditions that a plant needs have knowledge of. With this information, it is able to simulate the configuration of processes and assets for those conditions to improve or optimize operations, maintenance and asset management, using the IViewOps (Intelligent View of Operations) model...
January 4, 2018: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/29301543/towards-evidence-based-palliative-care-in-nursing-homes-in-sweden-a-qualitative-study-informed-by-the-organizational-readiness-to-change-theory
#17
Per Nilsen, Birgitta Wallerstedt, Lina Behm, Gerd Ahlström
BACKGROUND: Sweden has a policy of supporting older people to live a normal life at home for as long as possible. Therefore, it is often the oldest, most frail people who move into nursing homes. Nursing home staff are expected to meet the existential needs of the residents, yet conversations about death and dying tend to cause emotional strain. This study explores organizational readiness to implement palliative care based on evidence-based guidelines in nursing homes in Sweden. The aim was to identify barriers and facilitators to implementing evidence-based palliative care in nursing homes...
January 4, 2018: Implementation Science: IS
https://www.readbyqxmd.com/read/29301347/the-relationship-between-self-reported-executive-functioning-and-risk-taking-behavior-in-urban-homeless-youth
#18
Joshua Piche, Jaeson Kaylegian, Dale Smith, Scott J Hunter
Introduction: Almost 2 million U.S. youth are estimated to live on the streets, in shelters, or in other types of temporary housing at some point each year. Both their age and living situations make them more likely to engage in high-risk behaviors, particularly during adolescence, a time of increased risk taking. Much of self-control appears related to the development of the prefrontal cortex, which is at a particularly crucial period of elaboration and refinement during adolescence and emerging adulthood...
January 3, 2018: Behavioral Sciences
https://www.readbyqxmd.com/read/29300204/the-association-between-the-severity-and-level-of-understanding-of-depression-among-patients-treated-with-antidepressants-a-survey-of-424-outpatients-in-japan
#19
Tetsu Tomita, Norio Yasui-Furukori, Shuhei Kudo, Norio Sugawara, Akira Fujii, Koji Tsuruga, Yasushi Sato, Masamichi Ishioka, Kazuhiko Nakamura
OBJECTIVES: The present study investigated the association between the severity and knowledge of depression and attempted to reveal the specific aspects of understanding associated with severity. METHODS: A total of 424 outpatients were enrolled in this study. We used an original self-administered questionnaire: (a) the symptoms of depression, (b) the course of depression, (c) the cause of depression, (d) the treatment plan, (e) the duration of antidepressant use, (f) how to discontinue antidepressant use, (g) the adverse effects of antidepressants, and (h) psychotherapy...
January 3, 2018: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/29296663/computer-assisted-retrosynthesis-based-on-molecular-similarity
#20
Connor W Coley, Luke Rogers, William H Green, Klavs F Jensen
We demonstrate molecular similarity to be a surprisingly effective metric for proposing and ranking one-step retrosynthetic disconnections based on analogy to precedent reactions. The developed approach mimics the retrosynthetic strategy defined implicitly by a corpus of known reactions without the need to encode any chemical knowledge. Using 40 000 reactions from the patent literature as a knowledge base, the recorded reactants are among the top 10 proposed precursors in 74.1% of 5000 test reactions, providing strong quantitative support for our methodology...
December 27, 2017: ACS Central Science
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