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Asthma non invasive ventilation

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https://www.readbyqxmd.com/read/27903208/early-experience-of-a-new-extracorporeal-carbon-dioxide-removal-device-for-acute-hypercapnic-respiratory-failure
#1
Ravindranath Tiruvoipati, Hergen Buscher, James Winearls, Jeff Breeding, Debasish Ghosh, Shimonti Chaterjee, Gary Braun, Eldho Paul, John F Fraser, John Botha
BACKGROUND: Recent advances in the technology of extracorporeal respiratory assist systems have led to a renewed interest in extracorporeal carbon dioxide removal (ECCOR). The Hemolung is a new, low-flow, venovenous, minimally invasive, partial ECCOR device that has recently been introduced to clinical practice to aid in avoiding invasive ventilation or to facilitate lung-protective ventilation. OBJECTIVE: We report our early experience on use, efficacy and safety of the Hemolung in three Australian intensive care units...
December 2016: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/27875593/enterovirus-d68-in-hospitalized-children-sequence-variation-viral-loads-and-clinical-outcomes
#2
Katherine Moyer, Huanyu Wang, Douglas Salamon, Amy Leber, Asuncion Mejias
BACKGROUND: An outbreak of enterovirus D68 (EV-D68) caused severe respiratory illness in 2014. The disease spectrum of EV-D68 infections in children with underlying medical conditions other than asthma, the role of EV-D68 loads on clinical illness, and the variation of EV-D68 strains within the same institution over time have not been described. We sought to define the association between EV-D68 loads and sequence variation, and the clinical characteristic in hospitalized children at our institution from 2011 to 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27687114/non-invasive-positive-pressure-ventilation-for-acute-asthma-in-children
#3
Steven Kwasi Korang, Joshua Feinberg, Jørn Wetterslev, Janus C Jakobsen
BACKGROUND: Asthma is one of the most common reasons for hospital admission among children and constitutes a significant economic burden. Use of non-invasive positive pressure ventilation (NPPV) in the care of children with acute asthma has increased even though evidence supporting the intervention has been considered weak and clinical guidelines do not recommend the intervention. NPPV might be an effective intervention for acute asthma, but no systematic review has been conducted to assess the effects of NPPV as an add-on therapy to usual care in children with acute asthma...
September 30, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27545060/omalizumab-rescued-a-asthma-copd-overlap-syndrome-patient-from-a-status-asthmatics-under-the-icu-management
#4
Shunichi Gamo, Hideya Iijima, Yumika Seki, Ryo Horaguchi, Yuji Suda, Yuriko Shindoh
An atopic asthmatic of 65-year-old man who was complicated with COPD and treated with inhaled corticosteroid, long-acting β2 agonist, long-acting muscarinic antagonist, and leukotriene receptor antagonist was hospitalized with a severe asthmatic attack. He was intubated and went onto an artificial respirator. He was gradually relieved by repeated intravenous administration of high-dose corticosteroid, and a respirator was switched over to non-invasive positive pressure ventilation on 24th day. However, he repeated asthmatic attacks which needed corticosteroid to recover...
July 2016: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/27537430/down-s-syndrome-is-a-risk-factor-for-severe-lower-respiratory-tract-infection-due-to-respiratory-syncytial-virus
#5
Constanza Galleguillos, Bárbara Galleguillos, Guillermo Larios, Gonzalo Menchaca, Louis Bont, Jose A Castro-Rodriguez
AIM: Previous studies have suggested that Down's syndrome is an independent risk factor for severe respiratory infection due to respiratory syncytial virus (RSV). We compared the clinical characteristics of children with and without Down's syndrome hospitalised due to RSV. METHODS: This retrospective cohort study compared data from hospitalisations due to RSV lower respiratory tract infections (LRTI) in children under 14 years of age with (n = 58) and without (n = 58) Down's syndrome...
November 2016: Acta Paediatrica
https://www.readbyqxmd.com/read/27116362/pediatric-acute-asthma-exacerbations-evaluation-and-management-from-emergency-department-to-intensive-care-unit
#6
Brittany Pardue Jones, Geoffrey M Fleming, Jaime Kaye Otillio, Ishan Asokan, Donald H Arnold
OBJECTIVE: The goal of this report is to review available modalities for assessing and managing acute asthma exacerbations in pediatric patients, including some that are not included in current expert panel guidelines. While it is not our purpose to provide a comprehensive review of the National Asthma Education and Prevention Program (NAEPP) guidelines, we review NAEPP-recommended treatments to provide the full range of treatments available for managing exacerbations with an emphasis on the continuum of care between the ER and ICU...
August 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27062623/respiratory-support-for-children-in-the-emergency-department
#7
REVIEW
Andreas Schibler, Donna Franklin
Respiratory support in paediatric emergency settings ranges from oxygen delivery with subnasal oxygen to invasive mechanical ventilation. Recent data suggest that oxygen can cause reperfusion injuries and should be delivered with caution within well-defined clinical target ranges. Most mild to moderate respiratory distress conditions with an oxygen requirement may benefit from early use of continuous positive airway pressure. High-flow nasal cannula therapy (HFNC) is an emerging alternative way to support the inspiratory effort combined with oxygen delivery and positive expiratory pressures without the need of complicated equipment or good compliance from the child...
February 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27062622/acute-severe-asthma
#8
REVIEW
Colin Ve Powell
Acute exacerbations of asthma are very common reasons for a presentation to emergency departments. This paper focuses on defining the high-risk group, consideration of the concept of phenotypes of acute asthma, the assessment of severe and life-threatening exacerbations and an emphasis on the management of the more severe end of the exacerbation severity. A number of evidence-based guidelines exist throughout the world and are all slightly different. This reflects the poor evidence base for some of those recommendations...
February 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/26427923/triage-of-intermediate-care-patients-in-pediatric-hospitals
#9
Christiana M Russ, Michael Agus
BACKGROUND: Hospitalized children have a wide range of acuity and risk of decompensation. The objective of this study was to determine where pediatric patients are triaged when they present to pediatric hospitals needing intense monitoring and nursing care, but do not require invasive monitoring or technology. METHODS: We completed a telephone survey of pediatric hospitals in the United States with at least 2 non-neonatal pediatric wards and at least 50 acute inpatient beds...
October 2015: Hospital Pediatrics
https://www.readbyqxmd.com/read/25852934/recurrent-lung-atelectasis-from-fibrin-plugs-as-a-very-early-complication-of-bronchial-thermoplasty-a-case-report
#10
Nicola Facciolongo, Francesco Menzella, Mirco Lusuardi, Roberto Piro, Carla Galeone, Claudia Castagnetti, Alberto Cavazza, Cristiano Carbonelli, Luigi Zucchi, Pier Paolo Salsi
BACKGROUND: Bronchial thermoplasty (BT) is a new therapeutic option for severe refractory asthma not controlled despite high dose inhaled corticosteroids plus long-acting bronchodilators and omalizumab in selected cases. Risk of pulmonary atelectasis after BT in severe asthma has been described in literature, but no details have been reported on the possible mechanisms of the complication. CASE PRESENTATION: A 49-year-old male with severe uncontrolled asthma was referred to BT...
2015: Multidisciplinary Respiratory Medicine
https://www.readbyqxmd.com/read/25831649/clinical-course-and-outcome-of-acute-severe-asthma-status-asthmaticus-in-adults
#11
Ali Khawaja, Hira Shahzad, Murtaza Kazmi, Ali Bin Sarwar Zubairi
OBJECTIVE: To evaluate the clinical course and outcomes in patients with acute severe asthma in a tertiary care setting. METHODS: The retrospective cross-sectional study was conducted at the Aga Khan University Hospital, Karachi, and comprised data of patients of age 16 and above who were admitted with a diagnosis of acute severe asthma from January 2000 to December 2013. These patients had undergone clinical evaluation to assess the severity of illness as well as the complications and eventual outcomes...
November 2014: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/25406346/trends-in-prevalence-and-prognosis-in-subjects-with-acute-chronic-respiratory-failure-treated-with-noninvasive-and-or-invasive-ventilation
#12
Arnaud Gacouin, Stephane Jouneau, Julien Letheulle, Mallory Kerjouan, Pierre Bouju, Pierre Fillatre, Yves Le Tulzo, Jean Marc Tadié
BACKGROUND: The pattern and outcome of noninvasive ventilation (NIV) use in patients with acute or chronic respiratory disease other than COPD is not well known. The aims of this study were to investigate trends over time in underlying respiratory diseases, use of NIV, and outcomes in COPD and non-COPD patients with acute respiratory failure. METHODS: We made a retrospective analysis of data recorded prospectively from 1,113 subjects admitted between 1998 and 2012...
February 2015: Respiratory Care
https://www.readbyqxmd.com/read/25376643/is-non-invasive-ventilation-safe-in-acute-severe-asthma
#13
Michael Pallin, Mark Hew, Matthew T Naughton
BACKGROUND AND OBJECTIVE: The effect of non-invasive ventilation (NIV) in acute severe asthma is unclear and there are concerns regarding its safety. METHODS: We undertook a 5-year case-control review of mortality and morbidity associated with NIV use in acute severe asthma and compared this with asthma requiring invasive mechanical ventilation (IMV) and a control group with less severe asthma without ventilatory support. RESULTS: Eight hundred seventy-three patients had acute severe asthma of whom 30 were treated with NIV, 17 with IMV and 90 served as controls...
February 2015: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/25360811/clinical-risk-factors-for-life-threatening-lower-respiratory-tract-infections-in-children-a-retrospective-study-in-an-urban-city-in-malaysia
#14
Anna Marie Nathan, Fairuz Rani, Rachel Jiun Yi Lee, Rafdzah Zaki, Caroline Westerhout, I-Ching Sam, Lucy Chai See Lum, Jessie de Bruyne
AIM: Lower respiratory tract infections (LRTIs) are an important cause of morbidity and mortality, especially in low income countries. The aim of this study was to determine risk factors of life-threatening LRTIs in hospitalised children in Malaysia. METHODS: This retrospective study included children aged less than 18 years admitted for LRTIs over 13 months in a tertiary referral centre in Kuala Lumpur, Malaysia. Neonates, children with asthma and those with either no or a normal chest radiograph were excluded...
2014: PloS One
https://www.readbyqxmd.com/read/25352004/-non-invasive-ventilation
#15
Anders Bastiansen
Within the last decade the use of non-invasive ventilation has expanded. This article reviews the studies on non-invasive ventilation in the treatment of exacerbations of chronic obstructive pulmonary disease (COPD), cardiogenic pulmonary oedema, acute respiratory distress syndrome, asthma and neuromuscular disease. Its beneficial effect has primarily been found in exacerbations of COPD where it reduces mortality with a number needed to treat of ten when added to standard medical treatment. No other conclusive evidence of the superiority of non-invasive ventilation compared to other modalities has been shown...
May 26, 2014: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/25334605/incidence-of-postoperative-respiratory-depression-and-postoperative-apnea-in-the-obese-general-surgical-population
#16
Srikanth Sridhar, Evan Pivalizza, Julie Kim, Iwona Bonney, C Marshall MacNabb, Roman Schumann
SESSION TITLE: Patient Safety Initiative PostersSESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PMPURPOSE: According to the CDC, obstructive sleep apnea (OSA) occurs in 1 in 4 men and 1 in 10 women in the US. The prevalence increases in the obese population and OSA is a risk factor for post-operative respiratory complications. Current post-operative monitoring does not provide quantitative measurements of ventilation and the true incidence of post-operative respiratory depression (PORD) and apnea (POA) is unknown...
October 1, 2014: Chest
https://www.readbyqxmd.com/read/25310021/profile-of-acute-asthma-exacerbation-in-drug-users
#17
Viral Doshi, Sundeep Shenoy, Aarthi Ganesh, Muhammad Adeel Rishi, Janos Molnar, Joseph Henkle
The characteristics of patients who use heroin, cocaine, or both and present with acute asthma exacerbations have not been well studied. In this retrospective study, we aimed to study the demographic characteristics of this patient population, the characteristics of their asthma attack, and the risk factors for the need for invasive mechanical ventilation in this patient population. We reviewed the charts of patients discharged from an inner-city hospital with a diagnosis of acute asthma exacerbation. Individuals who used either heroin or cocaine or both within 24 hours of presenting to the emergency department were identified as a cohort of drug users...
October 10, 2014: American Journal of Therapeutics
https://www.readbyqxmd.com/read/25272791/-update-on-current-care-guideline-chronic-obstructive-pulmonary-disease-copd
#18
Terttu Harju, Hannu Kankaanranta, Milla Katajisto, Maritta Kilpeläinen, Lauri Lehtimäki, Juho Lehto, Witold Mazur, Tuula Meinander, Timo Peisa
Clinical serverity of COPD is based not only on the grade of obstruction in spirometry, but also on symptoms and risk of exacerbations. Symptoms can be defined by questionnaires, such as CAT-test (COPD assessment -test) or mMRC (modified Medical Research Council -test). Smoking cessation and physical activity are important treatment options. Pharmacological treatment is selected by symptoms, risk of exacerbations and co-occurrence of asthma and COPD. Non-invasive ventilation (NIV) is recommended in the treatment of severe hypercapnic exacerbations...
2014: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/25185981/breath-tests-in-diagnosis-of-pulmonary-tuberculosis
#19
Attapon Cheepsattayakorn, Ruangrong Cheepsattayakorn
Since the time of Hippocrates, physicians have known that the odour of human breath can provide clues to diagnosis. In the past, hydrogen peroxide which is a marker of inflammatory diseases and oxidative stress was the most studied substance in the exhaled breath which was detectable in the liquid that obtained by condensing or cooling. The advantages of breath analysis are that it is convenient, non-invasive, and could be performed with children as well as mechanically ventilated patients. Today, exhaled nitric oxide has been studied extensively, especially in relation to asthma...
2014: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/25157178/variation-in-treatment-of-acute-childhood-wheeze-in-emergency-departments-of-the-united-kingdom-and-ireland-an-international-survey-of-clinician-practice
#20
MULTICENTER STUDY
Mark D Lyttle, Ronan O'Sullivan, Iolo Doull, Stuart Hartshorn, Ian Morris, Colin V E Powell
OBJECTIVE: National clinical guidelines for childhood wheeze exist, yet despite being one of the most common reasons for childhood emergency department (ED) attendance, significant variation in practice occurs in other settings. We, therefore, evaluated practice variations of ED clinicians in the UK and Ireland. DESIGN: Two-stage survey undertaken in March 2013. Stage one examined department practice and stage two assessed ED consultant practice in acute childhood wheeze...
February 2015: Archives of Disease in Childhood
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