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Reproductive psychiatry

S-M Wei, E B Baller, P D Kohn, J S Kippenhan, B Kolachana, S J Soldin, D R Rubinow, P J Schmidt, K F Berman
Preclinical evidence suggests that the actions of ovarian steroid hormones and brain-derived neurotrophic factor (BDNF) are highly convergent on brain function. Studies in humanized mice document an interaction between estrus cycle-related changes in estradiol secretion and BDNF Val(66)Met genotype on measures of hippocampal function and anxiety-like behavior. We believe our multimodal imaging data provide the first demonstration in women that the effects of the BDNF Val/Met polymorphism on hippocampal function are selectively modulated by estradiol...
April 18, 2017: Molecular Psychiatry
Sarah Nagle-Yang, Laura Miller, Lauren M Osborne
No abstract text is available yet for this article.
April 6, 2017: Academic Psychiatry
Lauren M Osborne, Joanna V MacLean, Erin Murphy Barzilay, Samantha Meltzer-Brody, Laura Miller, Sarah Nagle Yang
OBJECTIVE: The reproductive life cycle has unique influences on the phenotypic expression of mental illness in women. Didactic and clinical training focused on these sex-specific influences should be a vital component of the education of future psychiatrists. The authors sought to determine the current state of and attitudes toward reproductive psychiatry in resident education. METHODS: The authors administered a web-based survey to psychiatry residency training directors...
February 13, 2017: Academic Psychiatry
Vedat Şar, Nazan Aydın, Onno van der Hart, A Steven Frankel, Meriç Şar, Oğuz Omay
This article presents the history of a 21-year-old female college student with total denial of pregnancy who experienced an acute dissociative reaction during the spontaneous delivery at home without medical assistance where the newborn died immediately. Psychiatric examination, self-report questionnaires, legal documents, and witness reports have been reviewed in evaluation of the case. Evidence pointed to total denial of pregnancy, that is, until delivery. The diagnoses of an acute dissociative reaction to stress (remitted) and a subsequent PTSD were established in a follow-up examination conducted 7 months after the delivery...
December 20, 2016: Journal of Trauma & Dissociation
Parvin Abedi, Najva Hazeghi, Poorandokht Afshari, Ahmad Fakhri
Extreme fear of childbirth may interfere with normal process of labor and increase the rate of cesarean section. The aim of this study was to evaluate validity and reliability of a Persian version of Wijma Delivery Expectancy/Experience Questionnaire (W-DEQ) among nulliparous women. In this cross-sectional study, 200 nulliparous women of reproductive age were recruited. The original form of the W-DEQ was received from corresponding author (Garthus-Niegel). This questionnaire was translated into Persian language and back-translated to English by three experts in reproductive health and psychiatry who were fluent in Persian and English...
July 27, 2016: Global Journal of Health Science
Pedro-Antonio Regidor, Claus D Volko, Adolf E Schindler, Uwe D Rohr
There are two forms of immune defense, the specific or adaptive immune defense and the unspecific innate immune defense. Vaccination is utilized against specific bacteria via the adaptive immune system. The innate immunity DNA stress defense is a non-toxic mechanism developed in yeasts and conserved in mammals and in plants. Although the steroidal hormone cascade has overtaken the stress response and allows superfast response via non-genomic receptors, the old innate immunity response is still mediated via the steroidal hormones cascade...
January 1, 2017: Hormone Molecular Biology and Clinical Investigation
Adeline Boatin, Joseph Ngonzi, Leslie Bradford, Blair Wylie, Annekathryn Goodman
INTRODUCTION: In Uganda, an estimated 120 obstetrician/gynecologists serve a population of 30 million people demonstrating the need to train additional skilled clinician leaders in reproductive health. In 2012, a partnership was formed with the Mbarara Regional Referral Hospital (MRRH) in southwest Uganda and the Massachusetts General Hospital (MGH) in Boston, USA, in part to increase access to specialist training. This report presents an update in the development of a teaching conference between the institutions...
November 2015: Open Journal of Obstetrics and Gynecology
Dorothy Gotlib, Elizabeth Perelstein, Jacob Kurlander, Kara Zivin, Michelle Riba, Maria Muzik
OBJECTIVE: Valproic acid (VPA) use during pregnancy increases fetal risk of major congenital malformations and cognitive impairment. Given these risks, several medical societies have put forth guidelines suggesting to either limit the use of VPA or take certain precautions, such as making sure effective contraception practices and/or appropriate folic acid supplementation are in place, when treating reproductive-aged women. Our study aimed to review and assess adherence to these guidelines...
April 2016: Journal of Clinical Psychiatry
Marlene P Freeman
Unplanned pregnancies account for approximately 50% of pregnancies in the United States and 40% globally. Therefore, it is good clinical practice to treat women of reproductive potential with the idea in mind that they may become pregnant during the course of treatment, regardless of their stated intentions. In psychiatry, most of the disorders we treat are chronic or recurrent; women are often on psychotropic medications during the reproductive years, and many will require pharmacologic treatment for psychiatric illnesses during pregnancy...
April 2016: Journal of Clinical Psychiatry
Maria Bernardete Cordeiro de Sousa, Ana Cecília de Menezes Galvão, Carla Jéssica Rodrigues Sales, Dijenaide Chaves de Castro, Nicole Leite Galvão-Coelho
Phenotypic sex differences in primates are associated with body differentiation during the early stages of life, expressed in both physiological and behavioral features. Hormones seem to play a pivotal role in creating a range of responses to meet environmental and social demands, resulting in better reactions to cope with challenges to survival and reproduction. Steroid hormones actively participate in neuroplasticity and steroids from both gonads and neurons seem to be involved in behavioral modulation in primates...
2015: Frontiers in Psychiatry
Alfonso Troisi
Medicalization of human behavioral diversity is a recurrent theme in the history of psychiatry, and the problem of defining what is a genuine mental disorder is an unresolved question since the origins of clinical psychopathology. Darwinian psychiatry can formulate a definition of mental disorder that is value free and based on factual criteria. From an evolutionary perspective, genuine mental disorders are maladaptive conditions. The ultimate function of an adaptation is gene propagation via maximization of survival and reproduction...
May 2015: Wiley Interdisciplinary Reviews. Cognitive Science
Ellen W Freeman
Ellen W Freeman is a Research Professor in the Department of Obstetrics/Gynecology and the Department of Psychiatry at the University of Pennsylvania School of Medicine in Philadelphia (PA, USA). She directs the PMS research program and is co-director of the Human Behavior and Reproduction unit in the Department of Obstetrics and Gynecology. She received her AB in history in Smith College in Northampton, Massachusetts and her MS and PhD in social research from Bryn Mawr College in Bryn Mawr, Pennsylvania. She has published more than 200 scientific articles, book chapters, reviews and abstracts on premenstrual syndromes, perimenopause, adolescent pregnancy, infertility and related topics as well as a book on teenage pregnancy...
July 2015: Women's Health
Alex B Neitzke
There is considerable discourse surrounding the disproportionate diagnosis of women with depression as compared to men, often times cited at a rate around 2:1. While this disparity clearly draws attention to gender, a focus on gender tends to fall away in the study and treatment of depression in neuroscience and psychiatry, which largely understand its workings in mechanistic terms of brain chemistry and neurological processes. I first consider how this brain-centered biological model for depression came about...
March 2016: Culture, Medicine and Psychiatry
Véronique Griner-Abraham
Among infertile couples who are undergoing the process of medically assisted reproduction, those for whom no biological cause for their infertility has been detected are offered a meeting with a liaison psychiatry team. They can then continue consultations with a psychiatrist in private practice. These consultations confront the couples with the various conflicts, injuries and impulses, buried in their unconscious which can cause symptoms of infertility. What is at play for these men and women and for the structure of each couple in its singularity?...
January 2015: Soins. Psychiatrie
Benoit Dubé, Marcia L Verduin
OBJECTIVE: This study examines how behavioral and physical health are currently integrated in undergraduate medical education, both in the classroom and during clinical rotations. METHODS: Members of the Association of Directors of Medical Student Education in Psychiatry (n = 215) were invited to complete a short survey on the integration of physical and behavioral health at their institution. RESULTS: In addition to undergraduate medical courses traditionally taught by psychiatrists, behavioral science topics are often addressed in neurology, reproduction, and doctoring courses...
August 2015: Academic Psychiatry
Heinz Häfner
With his early publications (1910-1913), Karl Jaspers created a comprehensive methodological arsenal for psychiatry, thus laying the foundation for descriptive psychopathology. Following Edmund Husserl, the founder of philosophical phenomenology, Jaspers introduced phenomenology into psychopathology as "static understanding," ie, the unprejudiced intuitive reproduction (Vergegenwärtigung) and description of conscious phenomena. In a longitudinal perspective, "genetic understanding" based on empathy reveals how mental phenomena arise from mental phenomena...
March 2015: Dialogues in Clinical Neuroscience
Véronique Griner-Abraham
Among infertile couples who are undergoing the process of medically assisted reproduction, those for whom no biological cause for their infertility has been detected are offered a meeting with a liaison psychiatry team. They can then continue consultations with a psychiatrist in private practice. These consultations confront the couples with the various conflicts, injuries and impulses, buried in their unconscious which can cause symptoms of infertility. What is at play for these men and women and for the structure of each couple in its singularity?...
January 2015: Soins. Psychiatrie
Esra Akyol Soydas, Yakup Albayrak, Basak Sahin
OBJECTIVE: Abuse is considered to have a place in the etiology of various psychiatric disorders. Premenstrual dysphoric disorder (PMDD) is one of the psychiatric disorders for which abuse could be an etiologic factor; however, few studies have investigated the relationship between abuse and PMDD. In this study, our aim was to investigate childhood abuse in patients with PMDD and compare them with healthy female subjects. METHOD: This cross-sectional study included 70 women with PMDD (DSM-IV-TR criteria) who were admitted to the outpatient psychiatry clinic of Ankara Yenimahalle State Hospital, Ankara, Turkey, between December 2012 and December 2013...
2014: Primary Care Companion to CNS Disorders
Randolph M Nesse, Stephen C Stearns
Evolutionary biology is an essential basic science for medicine, but few doctors and medical researchers are familiar with its most relevant principles. Most medical schools have geneticists who understand evolution, but few have even one evolutionary biologist to suggest other possible applications. The canyon between evolutionary biology and medicine is wide. The question is whether they offer each other enough to make bridge building worthwhile. What benefits could be expected if evolution were brought fully to bear on the problems of medicine? How would studying medical problems advance evolutionary research? Do doctors need to learn evolution, or is it valuable mainly for researchers? What practical steps will promote the application of evolutionary biology in the areas of medicine where it offers the most? To address these questions, we review current and potential applications of evolutionary biology to medicine and public health...
February 2008: Evolutionary Applications
Marlene P Freeman
Attention deficit hyperactivity disorder (ADHD) has been increasingly recognized and treated in children and adults in recent years. As a result, a growing number of women enter their reproductive years treated with medication for ADHD or are diagnosed and start medication during their reproductive years. A common question in perinatal psychiatry regards the risk-benefit profile of pharmacotherapy for ADHD, particularly with stimulants. At this time, there are no guidelines to inform the treatment of ADHD across pregnancy and the postpartum period...
July 2014: American Journal of Psychiatry
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