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brachial plexus lesions

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https://www.readbyqxmd.com/read/29510417/development-of-a-device-assisted-nerve-regeneration-procedure-in-disruptive-lesions-of-the-brachial-plexus
#1
Antonio Merolli, Maria Lucia Manunta, Yong Mao, Gerolamo Masala, Giovanni Mario Careddu, Francesca Cubeddu, Maria Antonietta Evangelisti, Maria Letizia Guida, Caroline Antonia Verardi, Claudio Proietti, Andrea Manunta, Giuseppe Falvo D'Urso Labate, Gerardo Catapano, Marianne Polunas, Pedro Louro, Eraldo Sanna Passino
BACKGROUND:  We describe the development of a new surgical procedure to be used in the treatment of disruptive brachial plexus (BP) lesions. It is centered on an artificial device designed to assist nerve regeneration by providing a confined and protected environment. Nerve fibers can repair inside the device, while the adverse massive scar-tissue formation is limited to the outside of the device. METHODS:  Steps in the development of the procedure were (1) definition of the rationale, (2) design of the device, (3) choice of an in vivo translational model, (4)refinement of the surgical procedure, and (5) performance of an in vivo pilot study as a proof of concept...
March 6, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29461642/brachial-plexitis-or-neuritis-mri-features-of-lesion-distribution-in-parsonage-turner-syndrome
#2
Darryl B Sneag, Schneider K Rancy, Scott W Wolfe, Susan C Lee, Vivek Kalia, Steve K Lee, Joseph H Feinberg
INTRODUCTION: This study seeks to characterize lesion distribution in Parsonage-Turner Syndrome (PTS) using high-resolution MRI. METHODS: MRIs of 27 patients with clinically confirmed PTS were reviewed. Two radiologists independently evaluated the brachial plexus proper, side and terminal plexus branches, and more distal, upper extremity nerves. RESULTS: All patients had at least 1 clinically involved nerve. MRI revealed that the plexus appeared normal in 24 of 27 patients; in 3 other patients, signal hyperintensity was seen immediately proximal to the take-off of abnormal side or terminal branch nerves...
February 20, 2018: Muscle & Nerve
https://www.readbyqxmd.com/read/29453752/satisfied-patients-after-shoulder-arthrodesis-for-brachial-plexus-lesions-even-after-20-years-of-follow-up
#3
M A J van der Lingen, S G C J de Joode, M G M Schotanus, B Grimm, F A van Nie, L A W M Speth, S K Samijo
PURPOSE: Patients with an upper brachial plexus lesion can suffer from dysfunction, joint deformities and instability of the shoulder. The goal of this study was to determine pain, shoulder function, patient satisfaction and muscle strength in shoulder arthrodesis in patients with an upper brachial plexus lesion more than 15 years after surgery. METHODS: We retrospectively studied 12 patients with a brachial plexus lesion of mean age 46 years (27-61). At a mean of 19...
February 16, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29446814/nerve-surgery-in-obstetric-brachial-plexus-palsy-report-of-68-cases
#4
Maher Barsaoui, Hatem Safi, Walid Said, Med Nabil Nessib
BACKGROUND: Obstetric brachial plexus palsy aredue to elongation of the brachial plexus during delivery by increasing thedistance between the head and shoulder. The majority of paralysis recoverspontaneously, but in some cases, nerve repair is necessary. The timing of thisnerve surgery and criteria for its indication are topics of discussion in theworld literature.The aim of this study is to askdirections and to evaluate the contribution of nerve surgery in improving theprognosis of this disease...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29372877/early-nerve-repair-in-traumatic-brachial-plexus-injuries-in-adults-treatment-algorithm-and-first-experiences
#5
Willem Pondaag, Finn Y van Driest, Justus L Groen, Martijn J A Malessy
OBJECTIVE The object of this study was to assess the advantages and disadvantages of early nerve repair within 2 weeks following adult traumatic brachial plexus injury (ATBPI). METHODS From 2009 onwards, the authors have strived to repair as early as possible extended C-5 to C-8 or T-1 lesions or complete loss of C-5 to C-6 or C-7 function in patients in whom there was clinical and radiological suspicion of root avulsion. Among a group of 36 patients surgically treated in the period between 2009 and 2011, surgical findings in those who had undergone treatment within 2 weeks after trauma were retrospectively compared with results in those who had undergone delayed treatment...
January 26, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29355794/surgical-results-of-common-peroneal-nerve-neuroplasty-at-lateral-fibular-neck
#6
John Souter, Kevin Swong, Matthew McCoyd, Neelam Balasubramanian, Magan Nielsen, Vikram C Prabhu
BACKGROUND: Common peroneal nerve (CPN) compressive neuropathy is the most common lower-extremity entrapment neuropathy. MATERIALS AND METHODS: A retrospective review of a prospectively maintained single-institution database of all patients with CPN palsy who underwent decompression and neuroplasty over a 5-year period was performed. RESULTS: Thirty patients underwent a neuroplasty of the CPN over a 5-year period (2010-2015) at our institution...
April 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29338908/relationship-between-neuropathy-proximal-to-the-suprascapular-nerve-and-rotator-cuff-tear-in-a-rodent-model
#7
Yasuhito Sasaki, Nobuyasu Ochiai, Eiko Hashimoto, Yu Sasaki, Takeshi Yamaguchi, Takehiro Kijima, Koji Akimoto, Seiji Ohtori, Kazuhisa Takahashi
BACKGROUND: Rotator cuff tears are believed to coexist with cervical spine lesions. In cases of preexisting neuropathy, such as cervical spine lesions, fatty degeneration has likely already occurred due to the neuropathy. In these cases, rotator cuff tear is thought to occur easily because of preexisting extensive fatty degeneration and degeneration of the tendons due to neuropathy. This study aimed to evaluate the effects of paralysis due to neuropathy proximal to the suprascapular nerve on the supraspinatus and infraspinatus tendons using a rat model of brachial plexus paralysis...
March 2018: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29323028/surgical-reconstruction-of-spinal-cord-circuit-provides-functional-return-in-humans
#8
REVIEW
Thomas Carlstedt, Nicholas James, Mårten Risling
This mini review describes the current surgical strategy for restoring function after traumatic spinal nerve root avulsion in brachial or lumbosacral plexus injury in man. As this lesion is a spinal cord or central nervous injury functional return depends on spinal cord nerve cell growth within the central nervous system. Basic science, clinical research and human application has demonstrated good and useful motor function after ventral root avulsion followed by spinal cord reimplantation. Recently, sensory return could be demonstrated following spinal cord surgery bypassing the injured primary sensory neuron...
December 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/29298281/an-experimental-model-of-the-dual-diagnosis-effect-of-cytotoxic-brain-edema-plus-peripheral-neuropathy-on-the-spontaneous-locomotor-activity-of-rats
#9
Petr Kozler, Dana Maresova, Jaroslav Pokorny
OBJECTIVE: The aim of the study was to find how a simultaneous impairment of the CNS (cellular brain edema induced by water intoxication) and PNS (blockade of the right forelimb brachial plexus by local anesthewtic - Marcaine) affects spontaneous locomotor activity of adult rats. METHODS: Rats were divided into groups of animals without water intoxication (without WI) - A,B,C, and those that were water intoxicated (induction of brain edema - after WI) - D,E,F. Both groups were further divided into intact ones (A,D), animals with PNS lesion (Marcaine) (B,E) and sham-operated animals (C,F)...
December 2017: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/29286963/restricted-range-of-motion-and-a-cold-upper-extremity-in-a-two-year-old-boy-kaposiform-hemangioendothelioma-of-the-bone-and-the-brachial-plexus-a-case-report
#10
Sachi Patel, Sonia Kamath, Nick M Shillingford, Chadi Zeinati, Vernon Tolo, Minnelly Luu
CASE: We report a case of kaposiform hemangioendothelioma (KHE) of the scapula in a 2-year-old boy with motor and sensory abnormalities of the left upper extremity, suggesting brachial plexus involvement. The locally invasive nature prevented resection; sirolimus therapy resulted in improvement of the motor and sensory impairment, as well as decreased tumor size on imaging. CONCLUSION: Osseous infiltration of KHE is known to occur, but its primary presentation in bone without skin involvement is rare and diagnostically challenging...
October 2017: JBJS Case Connector
https://www.readbyqxmd.com/read/29275608/-application-of-the-supine-position-in-microsurgery-for-lesions-of-the-cerebellopontine-angle
#11
J Q Li, G Chen, X Li, Z Wang, D Zhou
Objective: To validate the usefulness of the supine position in microsurgery for lesions of the cerebellopontine angle (CPA) by the retrosigmoid approach. Methods: Thirty-nine patients with lesions (22 cases of tumor, 11 cases of trigeminal neuralgia and 6 cases of hemifacial spasm) of the CPA underwent tumor resection surgery or microvascular decompression surgery (MVDS). The patients were operated on in the supine position by retrosigmoid approach with the head turned 50 to 60 degrees away from the lesion and with slight forward flexion of the neck...
December 12, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29221280/transmanubrial-osteomuscular-sparing-approach-for-resection-of-cervico-thoracic-lesions
#12
Xufeng Pan, Chang Gu, Rui Wang, Heng Zhao, Jun Yang, Jianxin Shi
Background: To review our experience of transmanubrial osteomuscular sparing approach (TMA) for resection of various lesions involving the thoracic inlet and to prove the feasibility and safety of the approach. Methods: Retrospective review of 58 consecutive cases, from April 2007 to January 2016, with surgical resection of cervico-thoracic lesions via TMA. Results: There were 22 neurogenic tumors, 21 bronchogenic tumors, and 15 other cases in the study...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29219757/spinal-accessory-nerve-to-triceps-muscle-transfer-using-long-autologous-nerve-grafts-for-recovery-of-elbow-extension-in-traumatic-brachial-plexus-injuries
#13
Liselotte F Bulstra, Nadia Rbia, Michelle F Kircher, Robert J Spinner, Allen T Bishop, Alexander Y Shin
OBJECTIVE Reconstructive options for brachial plexus lesions continue to expand and improve. The purpose of this study was to evaluate the prevalence and quality of restored elbow extension in patients with brachial plexus injuries who underwent transfer of the spinal accessory nerve to the motor branch of the radial nerve to the long head of the triceps muscle with an intervening autologous nerve graft and to identify patient and injury factors that influence functional triceps outcome. METHODS A total of 42 patients were included in this retrospective review...
December 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29170006/-intraneural-cyst-of-the-supraescapular-nerve-atypical-cause-of-peripheral-nerve-entrapment-syndrome-case-report-and-literature-review
#14
Beatriz Mansilla, Alberto Isla, María Román de Aragón, Borja Hernández, Pablo García Feijoo, Alexis Palpán Flores, Susana Santiago
OBJECTIVE: Intraneural cysts are benign lesions located within the epineurium of some peripheral nerves and their aetiopathogenesis is controversial. Most are located at the level of the lower limbs. In the upper limbs, the most frequently affected nerve is the ulnar nerve. Suprascapular nerve entrapment syndrome due to the formation of an intraneural cyst is rare. In this article, we show a new case and perform a literature review of intraneural cysts located in the suprascapular nerve...
November 20, 2017: Neurocirugía
https://www.readbyqxmd.com/read/29121071/from-nerves-to-brain-to-gastrointestinal-tract-a-time-based-study-of-parrot-bornavirus-2-pabv-2-pathogenesis-in-cockatiels-nymphicus-hollandicus
#15
Jeann Leal de Araujo, Raquel R Rech, J Jill Heatley, Jianhua Guo, Paula R Giaretta, Ian Tizard, Aline Rodrigues-Hoffmann
Parrot bornaviruses (PaBVs) are the causative agents of proventricular dilatation disease, however key aspects of its pathogenesis, such as route of infection, viral spread and distribution, and target cells remain unclear. Our study aimed to track the viral spread and lesion development at 5, 10, 20, 25, 35, 40, 60, 80, 95 and 114 dpi using histopathology, immunohistochemistry, and RT-PCR. After intramuscular inoculation of parrot bornavirus 2 (PaBV-2) in the pectoral muscle of cockatiels, this virus was first detected in macrophages and lymphocytes in the inoculation site and adjacent nerves, then reached the brachial plexus, centripetally spread to the thoracic segment of the spinal cord, and subsequently invaded the other spinal segments and brain...
2017: PloS One
https://www.readbyqxmd.com/read/29064032/-shoulder-dislocations-in-elderly-patients
#16
REVIEW
N Hawi, D Ratuszny, E Liodakis, M Omar, C Krettek, R Meller
In contrast to shoulder dislocations in younger patients, anterior shoulder dislocation in the elderly is often associated with concomitant injuries to the rotator cuff and fractures. There is also frequent involvement of the brachial plexus or peripheral nerves. After closed reduction and a short period of immobilization, physiotherapy should be performed to restore mobility and strength. The evaluation of the rotator cuff is essential for further treatment decisions. The majority of patients are classically treated conservatively...
October 24, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/29062825/relationship-of-age-and-type-of-obstetric-brachial-plexus-paralysis-in-forearm-pronosupination
#17
Yussef Ali Abdouni, Gabriel Faria Checoli, Valdênia das Graças Nascimento, Antonio Carlos da Costa, Ivan Chakkour, Patricia Maria de Moraes Barros Fucs
OBJECTIVE: To evaluate the arc of forearm pronosupination of patients with sequelae of birth paralysis and correlate with these variables. METHODS: 32 children aged between 4 and 14 years with total or partial lesions of the brachial plexus were evaluated; measurements of pronation and supination, active and passive, were made, both on the injured side and the unaffected side. RESULTS: A statistically significant difference was observed between the injured side and the normal side, but there was no difference between the groups regarding age or type of injury...
September 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/29061956/oxycodone-resistance-due-to-rifampin-use-in-an-osteosarcoma-patient-with-tuberculosis
#18
Akio Sakamoto, Manato Yamashita, Yuta Hori, Takeshi Okamoto, Atsushi Shimizu, Shuichi Matsuda
BACKGROUND Oxycodone is a semisynthetic opioid receptor agonist, and is frequently used for pain control in patients with cancer. Most oxycodone is metabolized by N-demethylation to noroxycodone by CYP3A. Rifampin is a strong inducer of several drug-metabolizing enzymes, including CYP3A. Hence, rifampin-induced CYP3A activity may decrease the effect of oxycodone. CASE REPORT Osteosarcoma is a highly aggressive primary bone tumor of childhood and adolescence. Here, we report a 30-year-old male with osteosarcoma of the femur with lung metastases in the upper lobe...
October 24, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29058949/lipomas-of-the-brachial-plexus-a-case-series-and-review-of-the-literature
#19
Alexander Graf, Kai Yang, David King, William Dzwierzynski, James Sanger, Patrick Hettinger
BACKGROUND: Lipomas are common benign tumors. When they develop in proximity to peripheral nerves, they can cause neurologic symptoms secondary to mass effect. Previous reports have shown symptom resolution after removal of lipomas compressing various upper extremity peripheral nerves. However, brachial plexus lipomas are relatively rare. Our multidisciplinary experience with brachial plexus lipoma resection is reviewed in the largest case series to date. METHODS: A retrospective chart review of all patients undergoing resection of brachial plexus lipomatous tumors between 2006 and 2016 was performed...
October 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29040777/efficient-imaging-examining-the-value-of-ultrasound-in-the-diagnosis-of-traumatic-adult-brachial-plexus-injuries-a-systematic-review
#20
Brian Chin, Maleka Ramji, Forough Farrokhyar, James R Bain
INTRODUCTION: Traumatic brachial plexus injury (BPI) can result in debilitating sequelae of the upper extremity. Presently, therapeutic decisions are based on the mechanism of injury, serial physical examination, electromyography, nerve conduction, and imaging studies. While magnetic resonance imaging is the current imaging modality of choice for BPI, ultrasound is a promising newcomer that is inexpensive, accessible, and available at point of care. OBJECTIVE: To evaluate ultrasound as a diagnostic tool in the assessment of traumatic adult BPI through a systematic review...
October 11, 2017: Neurosurgery
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