Giulia Nannini, Leandro Di Gloria, Edda Russo, Gaetana Sterrantino, Seble Tekle Kiros, Marco Coppi, Elena Niccolai, Simone Baldi, Matteo Ramazzotti, Vincenzo Di Pilato, Filippo Lagi, Gianluca Bartolucci, Gian Maria Rossolini, Alessandro Bartoloni, Amedeo Amedei
PURPOSE: Few reports focused on the role of oral microbiome diversity in HIV infection. We characterized the microbiota-immunity axis in a cohort of treatment-naïve HIV-1-infected patients undergoing antiretroviral therapy (ART) focusing on the oral microbiome (OM) and immunological responsivity. METHODS: The sequencing of 16S rRNA V3-V4 hypervariable region was performed on salivary samples of 15 healthy control (HC) and 12 HIV+ patients before starting ART and after reaching virological suppression...
April 16, 2024: Microbes and Infection