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voluntary blood donation

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https://www.readbyqxmd.com/read/28902419/reassessing-the-safety-concerns-of-utilizing-blood-donations-from-patients-with-hemochromatosis
#1
REVIEW
Adam C Winters, Douglas Tremblay, Suzanne Arinsburg, John Mascarenhas, Thomas D Schiano
Hereditary hemochromatosis (HH) is a genetic disorder of iron metabolism which may lead to iron overload. Clinical penetrance is low, however those afflicted may develop cirrhosis, hepatocellular carcinoma, diabetes mellitus and cardiomyopathy. Treatment involves regular phlebotomy to reduce the systemic iron burden. In many countries-including the United States-numerous blood centers do not accept donated blood obtained from HH patients during therapeutic phlebotomy and there are inconsistent positions regarding this globally...
September 13, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28866696/multiplex-real-time-rt-pcr-assay-for-transfusion-transmitted-viruses-in-sero-negative-allogeneic-blood-donors-an-experience-from-southern-pakistan
#2
S Sultan, M I Nasir, S Rafiq, M A Baig, S Akbani, S M Irfan
BACKGROUND: Blood transfusion safety commences with healthy donor recruitment. The threat of transfusion transmitted infections is greatly minimized by serological tools but not entirely eliminated. Recently, nucleic-acid testing for blood donor screening has virtually eliminated this jeopardy. METHODS: This prospective study was conducted from February 2015 to February 2016. Samples from seronegative donors were run on multiplex assay (Cobas, S-201 system platform, Roche) in a batch of six [MP-NAT]...
August 2017: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/28863010/faecal-microbiota-transplantation-establishment-of-a-clinical-application-framework
#3
Simon M D Jørgensen, Mette M Hansen, Christian Erikstrup, Jens F Dahlerup, Christian L Hvas
BACKGROUND: Faecal microbiota transplantation (FMT) is currently being established as a second-line treatment for recurrent Clostridium difficile infection. FMT is further being considered for other infectious and inflammatory conditions. Safe and reproducible methods for donor screening, laboratory processing and clinical application of FMT are warranted. METHODS: Here, we describe the development of a complete clinical application framework for FMT. The framework has been developed to comply with the European Tissue Act, thus considering donor faeces for FMT comparable to a human tissue and not a drug...
August 31, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28722278/non-physician-health-care-workers-and-voluntary-blood-donation-an-ambiguous-relationship
#4
N Sousos, S Sfyridou, D Adamidou, T-A Vyzantiadis, M Karadosidou, A Filippou, T Karafoulidou, M Chouridi, S Theodoridou
OBJECTIVES: This study aims to assess the knowledge, attitude and practice (KAP) of voluntary blood donation (BD) among the non-physician health-care workers of our institution, to investigate the relationship between these parameters and to determine the predictors of BD practice. BACKGROUND: KAP surveys provide a popular context-specific evidence base for the development of blood transfusion services' strategies and interventions to promote voluntary, non-remunerated BD...
July 19, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28712312/near-full-length-genome-sequence-of-a-novel-hiv-1-second-generation-recombinant-form-crf01_ae-crf07_bc-detected-among-blood-donors-in-north-china
#5
Wei He, Xiaoxu Han, Minghui An, Yanqiu Hai, Le Chang, Chao Liu, Lunan Wang, Hong Shang
In this study, a novel CRF01_AE/07_BC HIV-1 recombinant form, with five breakpoints in the pol, vpr, env, and nef gene regions, was identified from a voluntary blood donor in North China. Our study showed that this HIV-1 recombinant form might be a second-generation recombinant form from two predominant strains in the men who have sex with men (MSM) population, with the CRF07_BC fragments belonging to a CRF07_BC lineage specific to Chinese MSM and the CRF01_AE fragments belonging to the CRF01_AE lineage 5 common among MSM in northern China...
August 16, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28712183/association-of-abo-and-rh-blood-group-types-to-hepatitis-b-hepatitis-c-hiv-and-syphilis-infection-a-five-year-experience-in-healthy-blood-donors-in-a-tertiary-care-hospital
#6
Zufishan Batool, Saadia Haroon Durrani, Shazia Tariq
BACKGROUND: Aim of the study: The aim of the study was to find out the frequency of Hepatitis B Hepatitis C, Syphilis, HIV and malaria in apparently healthy blood donors and to find out any association between ABO and Rh blood groups. METHODS: It was a descriptive study carried out at Rehman Medical Institute laboratory. All blood donors who volunteered for blood donation from Jan 2008 to Dec 2014 were reviewed for blood groups and screening tests. Those who were eligible were then screened for Hepatitis B, Hepatitis C, HIV, syphilis and malaria on Architect 8200i through chemiluminescent immunoassay whereas malaria was screened by a thin film...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28705549/-voluntary-and-non-remunerated-blood-donation-current-situation-and-perspectives
#7
M Monsellier
The voluntary and unpaid blood donation is recommended by all international authorities (WHO, Council of Europe, ISBT, EBA), because it represents the best way of aiming towards self-sufficiency in blood products of all kinds, while preserving an optimal level of quality and safety for recipients as for donors. Still infrequent in many developing countries it tends to develop. However, the objective assigned by the WHO to reach 100% of unpaid and voluntary blood donations in 2020 appears ambitious, in particular for the collection of plasma intended to the splitting industry...
July 10, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28678865/transfusion-transmissible-viral-infections-among-blood-donors-at-the-north-gondar-district-blood-bank-northwest-ethiopia-a-three-year-retrospective-study
#8
Belete Biadgo, Elias Shiferaw, Berhanu Woldu, Kefyalew Addis Alene, Mulugeta Melku
BACKGROUND: Transfusion-transmissible viral infections, such as hepatitis C virus (HCV), hepatitis B virus (HBV), and human immunodeficiency virus (HIV), remain a major public health problem in developing countries. The prevalence of these viral infections among blood donors may reflect the burden of these diseases among populations. Therefore, the aim of this study was to assess the sero-prevalence of transfusion-transmissible viral infections among blood donors. METHODS: A retrospective study was conducted using data obtained from registration books of blood donors from the Ethiopian North Gondar District Blood Bank from 2010 to 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28668498/how-to-reverse-first-time-donors-to-become-regular-donors-a-questionnaire-survey-in-estonia
#9
P Veerus, R Kullaste, K Pungas, T Aavik, K Lang
BACKGROUND: Donating blood in Estonia is non-remunerated and voluntary. Estonian Blood Service system has four independent regional blood centres that are responsible for blood collection, processing, screening and distribution of blood components to hospitals for clinical use. STUDY DESIGN: This research was carried out as a questionnaire survey. A questionnaire was developed to study lapsing first time donors' (FTD) blood donation experience, intention and willingness to donate again...
June 28, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28645645/determinants-of-plasma-donation-a-review-of-the-literature
#10
A Beurel, F Terrade, J-P Lebaudy, B Danic
The major contribution of Human Sciences in the understanding of the whole blood donation behavior has been through the study of individuals' motivations and deterrents to donate. However, if whole blood donation has been very widely studied in the last sixty years, we still know very little about plasma donation in voluntary non-remunerated environments. Yet, the need for plasma-derived products has been strongly increasing for some years, and blood collection agencies have to adapt if they want to meet this demand...
June 20, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/28610845/hemochromatosis-and-blood-donation
#11
REVIEW
Turid Aarhus Braseth, Tor Hervig, Anne Synnove Rosvik
The voluntary, unpaid, altruistic blood donor is a cornerstone of current transfusion medicine. The complexity of medical and ethical issues related to blood donation and hemochromatosis has led to a large number of studies related to the safety of the hemochromatosis donor and the quality of the blood components produced from these donations. The issue of accepting persons with HC as blood donors is diverting, both in Europe and worldwide and without joint guidelines. A questionnaire-based study was performed and mailed to all 25 blood bank leaders in Norway...
June 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28584455/hepatitis-c-virus-unnoticed-and-on-the-rise-in-blood-donor-screening-a-5-years-cross-sectional-study-on-seroprevalence-in-voluntary-blood-donors-from-central-india
#12
Purti Agrawal Saini, Preeti Rihal Chakrabarti, Amit V Varma, Shankhini Gambhir, Gargi Tignath, Priyanka Gupta
CONTEXT: The ultimate goal of a blood transfusion service is the provision of safe and adequate supply free from transfusion-transmitted infections (TTIs). TTIs not only threaten the recipient's safety, but they also increase disease burden. Seroprevalence of TTIs in healthy blood donors indirectly reflects the prevalence of these infections in the general healthy population. AIM AND OBJECTIVES: To study the seroprevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), and hepatitis C virus (HCV) in healthy donors at a tertiary care hospital-based blood bank...
April 2017: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/28577645/seroprevalence-cost-per-donation-and-reduction-in-blood-supply-due-to-positive-and-indeterminate-results-for-infectious-markers-in-a-blood-bank-in-lima-peru
#13
Jeel Moya-Salazar, Roberto Ubidia-Incio, Maritza Incio-Grande, Jorgelina L Blejer, Carlos A Gonzalez
INTRODUCTION: Safety in Transfusion Medicine is subject to regulations and government legislation within a total quality framework. The aim of this study was to evaluate the impact of seroprevalence and indeterminate results on lost units and cost per donation. METHODS: A prospective cross-sectional study was performed in the Blood Bank and Transfusion Therapy Department of the Hospital Central de la Policia Nacional del Perú in Lima, Peru. All completed donations (replacement/voluntary) without complications were included in this study...
April 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/28571144/seroprevalence-and-trends-of-transfusion-transmissible-infections-in-blood-donors-in-andaman-and-nicobar-islands-an-institutional-retrospective-study
#14
Sahil Sehgal, P S Shaiji, Rupinder Kaur Brar
INTRODUCTION: Transfusion Transmissible Infections (TTIs) such as Human Immunodeficiency Virus (HIV), Hepatitis B virus (HBV), Hepatitis C Virus (HCV) and syphilis pose a threat to blood safety in a developing country like India. AIM: To determine the prevalence of TTIs among healthy donors in Andaman and Nicobar Islands, India, and to further help in determination of the population subset to be focused on for enhancing blood donor pool. MATERIALS AND METHODS: This retrospective cross-sectional study was conducted on all voluntary and replacement donors in a tertiary health care centre in Andaman and Nicobar Islands for a period of three years...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28550979/status-of-blood-transfusion-in-world-health-organization-eastern-mediterranean-region-who-emr-successes-and-challenges
#15
REVIEW
Arezoo Darbandi, Pargol Mashati, Amir Yami, Arshia Gharehbaghian, Mehdi Tabrizi Namini, Ahmad Gharehbaghian
BACKGROUND: Blood products are used for patient treatment and survival in the cases of major surgery, hematological disorders or cancer therapy. Presently the main blood components are not yet replaceable by artificial products and all activities related to blood transfusion is highly dependent on the healthcare development of each country. The World Health Organization Eastern Mediterranean Region (WHO-EMR) comprises of 21 member states with variable socio-economic status effective on blood transfusion activities...
May 8, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28547759/blood-donors-attitudes-towards-voluntary-non-remunerated-donation-in-trinidad-and-tobago
#16
K S Charles, A Poon King, A Ramai, K Rajnath, D Ramkissoon, S Ramkissoon, C Ramlal, K Ramnarine, K Rampersad, G Legall, S Pooransingh, A D Chantry
OBJECTIVES: To assess the attitude towards voluntary non-remunerated blood donation among blood donors in Trinidad and Tobago (TRT). BACKGROUND: Blood donors in TRT are either family replacement (F/R, 87%) or remunerated (13%). There is chronic blood shortage and high seroreactivity for transfusion-transmissible infections (TTI) in donors. Converting existing to voluntary non-remunerated donors (VNRD) reduces the need to recruit news donors in achieving 100% VNRD...
May 26, 2017: Transfusion Medicine
https://www.readbyqxmd.com/read/28543021/a-30-year-systematic-review-and-meta-analysis-of-hepatitis%C3%A2-b-virus-among-blood-donors-in-mainland-china-revealing-increase-of-new-threats
#17
Zhan Gao, Yu Zhang, Hua Shan, Ling Shi, Jing Liu, Min Xu, Peibin Zeng, Yu Liu, Miao He
BACKGROUND: Although screening strategies have been routinely implemented in blood centers, the residual risk of transfusion-transmitted hepatitis B virus (HBV) still poses a public health concern in China. The aim of this study is to investigate the HBV blood screening reactive rate and to illustrate the demographics of the corresponding blood donors with revealing of heterogeneity between previous studies and discovering potentially negligent threats. STUDY DESIGN AND METHODS: Literature reporting the HBV screening reactive rate in Chinese blood donors was identified by systematic searching of four electronic databases...
August 2017: Transfusion
https://www.readbyqxmd.com/read/28515024/knowledge-attitude-and-practice-towards-blood-donation-among-health-care-providers-in-hospitals-at-bahir-dar-city-ethiopia
#18
Bayeh Abera, Beyan Mohammed, Wendmagegn Betela, Reshid Yimam, Adam Oljira, Merhab Ahmed, Wubet Tsega, Wondemagegn Mulu, Endalew Yizengaw
Like other sub-Saharan Africa, in Ethiopia there is a shortage of adequate and safe blood supplies. Health care providers are potential resource and promoter of voluntary blood donation. This study was conducted to determine the knowledge, attitude and practice towards blood donation among health care providers in Bahir Dar City, Ethiopia. Paper based questionnaire was distributed to 276 health care providers from May 01 to June 30, 2016. Overall, 42.8% had donated blood at least once. Of these, males accounted for 60%...
April 26, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28484511/reducing-risks-of-transfusion-transmitted-infections-in-a-resource-limited-hospital-based-blood-bank-the-case-of-the-yaound%C3%A3-university-teaching-hospital-cameroon
#19
C T Tagny, A Ndoumba, S Laperche, E Murphy, D Mbanya
BACKGROUND AND OBJECTIVES: Although interest in assessing risk of TTIs, very few trends in blood safety epidemiological data from resource-limited blood services are reported in the literature. This analysis aims at reporting trends in seroprevalences of TTIs in blood donations in the Yaoundé University Teaching Hospital (UTH) from 2011 to 2015 and to describe reasons for these changes. MATERIALS AND METHODS: All donations of 2015 were tested for HIV 1&2 antibodies and the P24 antigen, HBsAg, HCV antibody and the Treponema pallidum antibody...
August 2016: ISBT Science Series
https://www.readbyqxmd.com/read/28479593/can-a-decentralized-blood-system-ensure-self-sufficiency-and-blood-safety-the-lebanese-experience
#20
Antoine Haddad, Tarek Bou Assi, Olivier Garraud
Lebanon has adopted a liberal economic system that also applies to healthcare procurement. There is no national Lebanese blood transfusion service and the blood supply is divided between a large number of licensed (45 per cent) and unlicensed (55 per cent) blood banks, many of them issuing a very limited number of blood components. All blood banks are hospital based and operate the entire transfusion chain, from collection to the release of blood units. Blood donation is voluntary and non-remunerated in 20-25 per cent of donations; it relies principally on replacement donations...
May 7, 2017: Journal of Public Health Policy
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