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Thomas Byrd

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https://www.readbyqxmd.com/read/28630725/endoscopic-repair-of-hip-abductor-tears-outcomes-with-two-year-follow-up
#1
J W Thomas Byrd, Kay S Jones
Abductor lesions are increasingly recognized as a source of recalcitrant laterally based hip pain and dysfunction. There is a growing body of evidence that many of these may be amenable to endoscopic repair. To report the demographic data and outcomes of endoscopic hip abductor repair. Twelve patients underwent endoscopic abductor repair with 2-year follow-up. These patients were prospectively assessed with modified Harris hip and iHOT scores. The indications for surgery were clinical and MRI findings of symptomatic abductor tears that had failed conservative treatment...
January 2017: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/28616757/corr-insights-%C3%A2-complete-circumferential-osseous-extension-in-the-acetabular-rim-occurs-regardless-of-acetabular-coverage
#2
J W Thomas Byrd
No abstract text is available yet for this article.
June 14, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28607941/radiographic-diagnosis-of-pincer-type-femoroacetabular-impingement-a-systematic-review
#3
REVIEW
Chanseok Rhee, Tina Le Francois, J W Thomas Byrd, Mark Glazebrook, Ivan Wong
BACKGROUND: Femoroacetabular impingement (FAI) is a well-recognized condition that causes hip pain and can lead to early osteoarthritis if not managed properly. With the increasing awareness and efficacy of operative treatments for pincer-type FAI, there is a need for consensus on the standardized radiographic diagnosis. PURPOSE: To perform a systematic review of the evidence regarding imaging modalities and radiographic signs for diagnosing pincer-type FAI. STUDY DESIGN: Systematic review; Level of evidence, 4...
May 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28452300/a-comparison-of-seasonal-trends-in-asthma-exacerbations-among-children-from-geographic-regions-with-different-climates
#4
Julia A Wisniewski, Anne P McLaughlin, Philip J Stenger, James Patrie, Mark A Brown, Jane M El-Dahr, Thomas A E Platts-Mills, Nora J Byrd, Peter W Heymann
BACKGROUND: The fall peak in childhood asthma exacerbations is thought to be related to an increase in viral infections and allergen exposure when children return to school. Whether the seasonality of asthma attacks among children from different geographic regions follows similar trends is unclear. OBJECTIVE: To compare seasonal trends in asthma exacerbations among school-age children who lived in different geographic locations, with different climates, within the United States...
November 1, 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28446548/regional-left-ventricular-function-does-not-predict-survival-in-ischaemic-cardiomyopathy-after-cardiac-surgery
#5
David L Prior, Susanna R Stevens, Thomas A Holly, Michal Krejca, Alexandros Paraforos, Gerald M Pohost, Krysti Byrd, Tomasz Kukulski, Robert H Jones, Patrice Desvigne-Nickens, Padmini Varadarajan, Aman Amanullah, Grace Lin, Hussein R Al-Khalidi, Gabriel Aldea, Carlo Santambrogio, Andrzej Bochenek, Daniel S Berman
OBJECTIVES: To define the prognostic contribution of global and regional left ventricular (LV) function measurements in patients with ischaemic cardiomyopathy randomised to coronary artery bypass graft surgery (CABG) with (n=501) or without (n=499) surgical ventricular reconstruction (SVR). METHODS: Novel multivariable methods to analyse global and regional LV systolic function were used to better formulate prediction models for long-term mortality following CABG with or without SVR in the entire cohort of 1000 randomised SVR hypothesis patients...
April 26, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28438292/correlation-of-crtc1-3-maml2-fusion-status-grade-and-survival-in-mucoepidermoid-carcinoma
#6
Andrew C Birkeland, Susan K Foltin, Nicole L Michmerhuizen, Rebecca C Hoesli, Andrew J Rosko, Serena Byrd, Megan Yanik, Jacques E Nor, Carol R Bradford, Mark E Prince, Thomas E Carey, Jonathan B McHugh, Matthew E Spector, J Chad Brenner
OBJECTIVE: Mucoepidermoid carcinoma (MEC) is the most common malignant tumor of the salivary glands. Tumor stage and grade have historically been important predictors of survival. An oncogenic CRTC1- or CRTC3-MAML2 gene fusion has been identified in a number of MECs. Historically, these gene fusions have been associated with lower grade tumors and better survival. However, reported gene fusion rates and prognosis varies widely across studies, and have not controlled for tumor grade. We sought to identify gene fusion rates and outcomes in our cohort of MEC patients...
May 2017: Oral Oncology
https://www.readbyqxmd.com/read/28397242/use-of-anticoagulants-and-antiplatelet-in-patients-with-chronic-lymphocytic-leukaemia-treated-with-single-agent-ibrutinib
#7
Jeffrey A Jones, Peter Hillmen, Steven Coutre, Constantine Tam, Richard R Furman, Paul M Barr, Stephen J Schuster, Thomas J Kipps, Ian W Flinn, Ulrich Jaeger, Jan A Burger, Mei Cheng, Joi Ninomoto, Danelle F James, John C Byrd, Susan M O'Brien
Bleeding events have been observed among a subgroup of chronic lymphocytic leukaemia (CLL) patients treated with ibrutinib. We analysed data from two studies of single-agent ibrutinib to better characterize bleeding events and pattern of anticoagulation and antiplatelet use. Among 327 ibrutinib-treated patients, concomitant anticoagulation (11%) or antiplatelet use (34%) was common, but major bleeding was infrequent (2%). Bleeding events were primarily grade 1, and infrequently (1%) led to discontinuation. Among 175 patients receiving concomitant anticoagulant or antiplatelet agents, 5 had major bleeding events (3%)...
April 10, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28372702/editorial-commentary-hip-femoroacetabular-impingement-correction-risk-versus-reward-or-how-much-is-too-much
#8
EDITORIAL
J W Thomas Byrd
When performing arthroscopic surgical management of symptomatic cases of hip femoroacetabular impingement (FAI), it is important to consider how much cam lesion resection is required, if any. Generally, failure to adequately address a cam lesion could result in progressive damage to the articular cartilage. Thus, while it is important to consider exactly how much arthroscopic intervention is necessary to achieve successful results, the potential consequences of neglecting a cam lesion are at least as worrisome as the risks of indicated cam lesion treatment...
April 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28275031/nccn-guidelines-insights-chronic-lymphocytic-leukemia-small-lymphocytic-leukemia-version-1-2017
#9
William G Wierda, Andrew D Zelenetz, Leo I Gordon, Jeremy S Abramson, Ranjana H Advani, C Babis Andreadis, Nancy Bartlett, John C Byrd, Paolo Caimi, Luis E Fayad, Richard I Fisher, Martha J Glenn, Thomas M Habermann, Nancy Lee Harris, Francisco Hernandez-Ilizaliturri, Richard T Hoppe, Steven M Horwitz, Mark S Kaminski, Christopher R Kelsey, Youn H Kim, Susan Krivacic, Ann S LaCasce, Michael G Martin, Auayporn Nademanee, Pierluigi Porcu, Oliver Press, Rachel Rabinovitch, Nishitha Reddy, Erin Reid, Kenneth Roberts, Ayman A Saad, Erin D Snyder, Lubomir Sokol, Lode J Swinnen, Julie M Vose, Joachim Yahalom, Mary A Dwyer, Hema Sundar
Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are different manifestations of the same disease and managed in much the same way. The advent of novel CD20 monoclonal antibodies led to the development of effective chemoimmunotherapy regimens. More recently, small molecule inhibitors targeting kinases involved in a number of critical signaling pathways and a small molecule inhibitor of the BCL-2 family of proteins have demonstrated activity for the treatment of patients with CLL/SLL. These NCCN Guidelines Insights highlight important updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for CLL/SLL for the treatment of patients with newly diagnosed or relapsed/refractory CLL/SLL...
March 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28183528/transethnic-genome-wide-scan-identifies-novel-alzheimer-s-disease-loci
#10
Gyungah R Jun, Jaeyoon Chung, Jesse Mez, Robert Barber, Gary W Beecham, David A Bennett, Joseph D Buxbaum, Goldie S Byrd, Minerva M Carrasquillo, Paul K Crane, Carlos Cruchaga, Philip De Jager, Nilufer Ertekin-Taner, Denis Evans, M Danielle Fallin, Tatiana M Foroud, Robert P Friedland, Alison M Goate, Neill R Graff-Radford, Hugh Hendrie, Kathleen S Hall, Kara L Hamilton-Nelson, Rivka Inzelberg, M Ilyas Kamboh, John S K Kauwe, Walter A Kukull, Brian W Kunkle, Ryozo Kuwano, Eric B Larson, Mark W Logue, Jennifer J Manly, Eden R Martin, Thomas J Montine, Shubhabrata Mukherjee, Adam Naj, Eric M Reiman, Christiane Reitz, Richard Sherva, Peter H St George-Hyslop, Timothy Thornton, Steven G Younkin, Badri N Vardarajan, Li-San Wang, Jens R Wendlund, Ashley R Winslow, Jonathan Haines, Richard Mayeux, Margaret A Pericak-Vance, Gerard Schellenberg, Kathryn L Lunetta, Lindsay A Farrer
INTRODUCTION: Genetic loci for Alzheimer's disease (AD) have been identified in whites of European ancestry, but the genetic architecture of AD among other populations is less understood. METHODS: We conducted a transethnic genome-wide association study (GWAS) for late-onset AD in Stage 1 sample including whites of European Ancestry, African-Americans, Japanese, and Israeli-Arabs assembled by the Alzheimer's Disease Genetics Consortium. Suggestive results from Stage 1 from novel loci were followed up using summarized results in the International Genomics Alzheimer's Project GWAS dataset...
February 7, 2017: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
https://www.readbyqxmd.com/read/27973495/ultra-compact-and-low-threshold-thulium-microcavity-laser-monolithically-integrated-on-silicon
#11
Zhan Su, Nanxi Li, E Salih Magden, Matthew Byrd, P Purnawirman, Thomas N Adam, Gerald Leake, Douglas Coolbaugh, Jonathan D B Bradley, Michael R Watts
We demonstrate an ultra-compact and low-threshold thulium microcavity laser that is monolithically integrated on a silicon chip. The integrated microlaser consists of an active thulium-doped aluminum oxide microcavity beside a passive silicon nitride bus waveguide, which enables on-chip pump-input and laser-output coupling. We observe lasing in the wavelength range of 1.8-1.9 μm under 1.6 μm resonant pumping and at varying waveguide-microcavity gap sizes. The microlaser exhibits a threshold as low as 773 μW (226 μW) and a slope efficiency as high as 24% (48%) with respect to the pump power coupled into the silicon nitride bus waveguide (microcavity)...
December 15, 2016: Optics Letters
https://www.readbyqxmd.com/read/27931303/a-comparison-of-seasonal-trends-in-asthma-exacerbations-among-children-from-geographic-regions-with-different-climates
#12
Julia A Wisniewski, Anne P McLaughlin, Philip J Stenger, James Patrie, Mark A Brown, Jane M El-Dahr, Thomas A E Platts-Mills, Nora J Byrd, Peter W Heymann
BACKGROUND: The fall peak in childhood asthma exacerbations is thought to be related to an increase in viral infections and allergen exposure when children return to school. Whether the seasonality of asthma attacks among children from different geographic regions follows similar trends is unclear. OBJECTIVE: To compare seasonal trends in asthma exacerbations among school-age children who lived in different geographic locations, with different climates, within the United States...
November 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27885091/international-standards-on-food-and-environmental-radioactivity-measurement-for-radiological-protection-status-and-perspectives
#13
D Calmet, R Ameon, A Bombard, S Brun, F Byrde, J Chen, J-M Duda, M Forte, M Fournier, A Fronka, T Haug, M Herranz, A Husain, S Jerome, M Jiranek, S Judge, S B Kim, P Kwakman, J Loyen, M LLaurado, R Michel, D Porterfield, A Ratsirahonana, A Richards, K Rovenska, T Sanada, C Schuler, L Thomas, S Tokonami, A Tsapalov, T Yamada
Radiological protection is a matter of concern for members of the public and thus national authorities are more likely to trust the quality of radioactivity data provided by accredited laboratories using common standards. Normative approach based on international standards aims to ensure the accuracy or validity of the test result through calibrations and measurements traceable to the International System of Units. This approach guarantees that radioactivity test results on the same types of samples are comparable over time and space as well as between different testing laboratories...
April 1, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27852036/interim-analysis-of-a-phase-i-iia-trial-assessing-e39-gm-csf-a-folate-binding-protein-vaccine-to-prevent-recurrence-in-ovarian-and-endometrial-cancer-patients
#14
Doreen O Jackson, Kevin Byrd, Timothy J Vreeland, Diane F Hale, Garth S Herbert, Julia M Greene, Erika J Schneble, John S Berry, Alfred F Trappey, G T Clifton, Mark O Hardin, Jonathan Martin, John C Elkas, Thomas P Conrads, Kathleen M Darcy, Chad A Hamilton, George L Maxwell, George E Peoples
BACKGROUND: Folate binding protein(FBP) is an immunogenic protein over-expressed in endometrial(EC) and ovarian cancer(OC). We are conducting a phase I/IIa trial of E39 (GALE 301)+GM-CSF, an HLA-A2-restricted, FBP-derived peptide vaccine to prevent recurrences in disease-free EC and OC patients. This interim analysis summarizes toxicity, immunologic responses, and clinical outcomes to date. METHODS: HLA-A2+ patients were vaccinated(VG), and HLA-A2- or -A2+ patients were followed as controls(CG)...
February 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/27832410/corr-insights-%C3%A2-labral-reattachment-in-femoroacetabular-impingement-surgery-results-in-increased-10-year-survivorship-compared-with-resection
#15
J W Thomas Byrd
No abstract text is available yet for this article.
April 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27757105/mycobacteria-clumping-increase-their-capacity-to-damage-macrophages
#16
Cecilia Brambilla, Marta Llorens-Fons, Esther Julián, Estela Noguera-Ortega, Cristina Tomàs-Martínez, Miriam Pérez-Trujillo, Thomas F Byrd, Fernando Alcaide, Marina Luquin
The rough morphotypes of non-tuberculous mycobacteria have been associated with the most severe illnesses in humans. This idea is consistent with the fact that Mycobacterium tuberculosis presents a stable rough morphotype. Unlike smooth morphotypes, the bacilli of rough morphotypes grow close together, leaving no spaces among them and forming large aggregates (clumps). Currently, the initial interaction of macrophages with clumps remains unclear. Thus, we infected J774 macrophages with bacterial suspensions of rough morphotypes of M...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27687248/low-expression-of-galectin-3-is-associated-with-poor-survival-in-node-positive-breast-cancers-and-mesenchymal-phenotype-in-breast-cancer-stem-cells
#17
Matthias Ilmer, Nachman Mazurek, Michael Z Gilcrease, James C Byrd, Wendy A Woodward, Thomas A Buchholz, Kim Acklin, Karen Ramirez, Margarete Hafley, Eckhard Alt, Jody Vykoukal, Robert S Bresalier
BACKGROUND: Galectin-3 (Gal3) plays diverse roles in cancer initiation, progression, and drug resistance depending on tumor type characteristics that are also associated with cancer stem cells (CSCs). Recurrence of breast carcinomas may be attributed to the presence of breast CSCs (BCSCs). BCSCs exist in mesenchymal-like or epithelial-like states and the transition between these states endows BCSCs with the capacity for tumor progression. The discovery of a feedback loop with galectins during epithelial-to-mesenchymal transition (EMT) prompted us to investigate its role in breast cancer stemness...
September 29, 2016: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/27587620/nccn-guidelines-insights-non-hodgkin-s-lymphomas-version-3-2016
#18
Steven M Horwitz, Andrew D Zelenetz, Leo I Gordon, William G Wierda, Jeremy S Abramson, Ranjana H Advani, C Babis Andreadis, Nancy Bartlett, John C Byrd, Luis E Fayad, Richard I Fisher, Martha J Glenn, Thomas M Habermann, Nancy Lee Harris, Francisco Hernandez-Ilizaliturri, Richard T Hoppe, Mark S Kaminski, Christopher R Kelsey, Youn H Kim, Susan Krivacic, Ann S LaCasce, Matthew Lunning, Auayporn Nademanee, Oliver Press, Rachel Rabinovitch, Nishitha Reddy, Erin Reid, Kenneth Roberts, Ayman A Saad, Lubomir Sokol, Lode J Swinnen, Julie M Vose, Joachim Yahalom, Nadeem Zafar, Mary Dwyer, Hema Sundar, Pierluigi Porcu
Peripheral T-cell lymphomas (PTCLs) represent a relatively uncommon heterogeneous group of non-Hodgkin's lymphomas (NHLs) with an aggressive clinical course and poor prognosis. Anthracycline-based multiagent chemotherapy with or without radiation therapy followed by first-line consolidation with high-dose therapy followed by autologous stem cell rescue (HDT/ASCR) is the standard approach to most of the patients with newly diagnosed PTCL. Relapsed or refractory disease is managed with second-line systemic therapy followed by HDT/ASCR or allogeneic stem cell transplant, based on the patient's eligibility for transplant...
September 2016: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27583146/hip-arthroscopy-a-report-on-a-cohort-of-orthopaedic-surgeons
#19
J W Thomas Byrd, Kay S Jones, Paul C Chin
Successful hip arthroscopy depends on proper patient selection and reasonable patient expectations. The purpose of this study is to report the results of hip arthroscopy in orthopaedic surgeons who represent the most informed cohort. This report is based on a retrospective review of prospectively collected data among 24 orthopaedic surgeons (1 bilateral). Follow-up averaged 48 months (range 12-120 months). They were all males with an average age of 45 years (range 30-64 years). All improved with an average of 18 points (preoperative 75; post-operative 93); although one underwent repeat arthroscopy and one was converted to total hip arthroplasty at 54 months...
July 2016: Journal of Hip Preservation Surgery
https://www.readbyqxmd.com/read/27388160/pain-is-associated-with-missed-clinic-visits-among-hiv-positive-women
#20
Stella A Safo, Arthur E Blank, Chinazo O Cunningham, E Byrd Quinlivan, Thomas Lincoln, Oni J Blackstock
Pain is highly prevalent among HIV-positive individuals, with women representing a large subset of those with pain. However, little is known about the relationship between pain and retention in HIV medical care. Among a cohort of HIV-positive women of color, we evaluated the association between pain and retention in care, as measured by missed clinic visits. The Health Resources and Services Administration's Women of Color Initiative was a multi-site observational cohort study evaluating demonstration projects to engage HIV-positive women in medical care...
June 2017: AIDS and Behavior
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