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https://www.readbyqxmd.com/read/29160562/aqueous-extract-of-yellow-maca-lepidium-meyenii-improves-sperm-count-in-experimental-animals-but-response-depends-on-hypocotyl-size-ph-and-routes-of-administration
#1
L Sanchez-Salazar, G F Gonzales
Lepidium meyenii, a Peruvian plant growing over 4000 m.a.s.l., has effects on nutrition and fertility. The purpose of this study was to evaluate the sperm count in 105 male mice receiving boiled aqueous extract of yellow maca hypocotyls from different sizes, under different pH conditions and using two different routes of administration. Five mice per group were treated daily for 3 days with vehicle (oral and intraperitoneal) or maca aqueous extracts (5 mg/0.5 ml/day) belonging to the first, second, third and fourth categories, according to their hypocotyl size...
November 21, 2017: Andrologia
https://www.readbyqxmd.com/read/29137154/two-sulfur-glycoside-compounds-isolated-from-lepidium-apetalum-willd-protect-nrk52e-cells-against-hypertonic-induced-adhesion-and-inflammation-by-suppressing-the-mapk-signaling-pathway-and-raas
#2
Peipei Yuan, Xiaoke Zheng, Meng Li, Yingying Ke, Yang Fu, Qi Zhang, Xiaolan Wang, Weisheng Feng
Lepidium apetalum Willd has been used to reduce edema and promote urination. Cis-desulfoglucotropaeolin (cis-DG) and trans-desulfoglucotropaeolin (trans-DG) were isolated from Lepidium apetalum Willd, and caused a significant increase in cell viability in a hypertonic model in NRK52e cells. In the hypertonic model, cis-DG and trans-DG significantly promoted the cell viability of NRK52e cells and inhibited the elevation of Na⁺ in the supernatant, inhibited the renin-angiotensin-aldosterone (RAAS) system, significantly reduced the levels of angiotensin II (Ang II) and aldosterone (ALD), and lowered aquaporin-2 (AQP2) and Na⁺-K⁺ ATP content in renal medulla...
November 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29127920/uptake-and-phytotoxic-effect-of-benzalkonium-chlorides-in-lepidium-sativum-and-lactuca-sativa
#3
Adnan Hossain Khan, Mark Libby, Daniel Winnick, John Palmer, Mark Sumarah, Madhumita B Ray, Sheila M Macfie
Cationic surfactants such as benzalkonium chlorides (BACs) are used extensively as biocides in hospitals, food processing industries, and personal care products. BACs have the potential to reach the rooting zone of crop plants and BACs might thereby enter the food chain. The two most commonly used BACs, benzyl dimethyl dodecyl ammonium chloride (BDDA) and benzyl dimethyl tetradecyl ammonium chloride (BDTA), were tested in a hydroponic system to assess the uptake by and phytotoxicity to lettuce (Lactuca sativa L...
November 8, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29116530/plant-assays-and-avoidance-tests-with-collembola-and-earthworms-demonstrate-rehabilitation-success-in-bauxite-residue
#4
Gerard Finngean, Audrey O'Grady, Ronan Courtney
Bauxite residues are a by-product of alumina manufacture from bauxite ore and are commonly disposed of in purpose-built bauxite residue disposal areas (BRDAs). Revegetation is viewed as the most effective way to landscape and rehabilitate closed BRDAS and physicochemical assessment remains the primary indicator of rehabilitation success. Little is known about the ability of keystone mesofaunal species to colonise and establish in these environments yet the long-term success of rehabilitation is dependent on residues becoming suitable habitats for such groups...
November 7, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29102764/treatment-of-malaria-and-related-symptoms-using-traditional-herbal-medicine-in-ethiopia
#5
Sultan Suleman, Takele Beyene Tufa, Dereje Kebebe, Sileshi Belew, Yimer Mekonnen, Fanta Gashe, Seid Musa, Evelien Wynendaele, Luc Duchateau, Bart De Spiegeleer
ETHNOPHARMACOLOGICAL RELEVANCE: Medicinal plants have always been an integral part of different cultures in Ethiopia in the treatment of different illnesses including malaria and related symptoms. However, due to lack of proper documentation, urbanization, drought, acculturation and deforestation, there is an increased risk of losing this traditional knowledge. Hence, the use of the indigenous knowledge should be well documented and validated for potential future use. AIM OF THE STUDY: To gather and document information on medicinal plants which are used in the traditional treatment of malaria and related symptoms in Ethiopia...
November 1, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29080819/isolation-purification-and-antioxidant-activity-of-polysaccharides-from-the-leaves-of-maca-lepidium-meyenii
#6
Kang Caicai, Hao Limin, Zhang Liming, Zheng Zhiqiang, Yang Yongwu
Two fractions of polysaccharides (MLP-1 and MLP-2) were extracted from the leaves of maca (Lepidium Meyenii Walp.) by water, and purified using DEAE-52 ion exchange resin and sephadex G-200 clumns chromatography. An investigation was carried out for their structural characterization and antioxidant activity in vitro. The results indicated that MLP-1 was mainly composed of ribose, rhamnose, arabinose, xylose, mannose, glucose and galactose, with the molar ratio of 0.12:0.32:1.50:0.32:1.03:1.00:0.93; the MLP-2 was a homopolysaccharide composed of glucose...
October 25, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29073716/antitumor-activity-of-lepidium-latifolium-and-identification-of-the-epithionitrile-1-cyano-2-3-epithiopropane-as-its-major-active-component
#7
María Conde-Rioll, Consuelo Gajate, José J Fernández, Janny A Villa-Pulgarin, José G Napolitano, Manuel Norte, Faustino Mollinedo
Consumption of Brassica (Cruciferae) vegetables is associated with a reduced risk of cancer, but identification of the active components and insights into the underlying molecular events are scarce. Here we found that an extract of Lepidium latifolium, a cruciferous plant native to southern Europe, Mediterranean countries and Asia, showed in vitro cytotoxic activity, inducing caspase-dependent apoptosis, in a variety of human tumor cells, and the plant juice showed in vivo antitumor activity in a HT-29 human colon cancer xenograft mouse model...
October 26, 2017: Molecular Carcinogenesis
https://www.readbyqxmd.com/read/29065230/comparing-chemistry-and-bioactivity-of-burned-versus-decomposed-plant-litter-different-pathways-but-same-result
#8
Giuliano Bonanomi, Guido Incerti, Ahmed M Abd El-Gawad, Gaspare Cesarano, Tushar C Sarker, Luigi Saulino, Virginia Lanzotti, Antonio Saracino, Francisco C Rego, Stefano Mazzoleni
Litter burning and biological decomposition are oxidative processes co-occurring in many terrestrial ecosystems, producing organic matter with different chemical properties and differently affecting plant growth and soil microbial activity. We tested the chemical convergence hypothesis i.e. materials with different initial chemistry converge towards a common profile, with similar biological effects, as the oxidative process advances, for burning and decomposition. We compared the molecular composition, assessed by (13) C NMR, of 7 plant litter types either fresh, decomposed for 30, 90, 180 days in a microcosms incubation experiment, or heated at 100, 200, 300, 400, 500 °C for thirty minutes...
October 24, 2017: Ecology
https://www.readbyqxmd.com/read/29054647/pilot-scale-aided-phytoremediation-of-a-co-contaminated-soil
#9
Charlotte Marchand, Michel Mench, Yahya Jani, Fabio Kaczala, Peter Notini, Mohamed Hijri, William Hogland
A pilot scale experiment was conducted to investigate the aided-phytoextraction of metals and the aided-phytodegradation of petroleum hydrocarbons (PHC) in a co-contaminated soil. First, this soil was amended with compost (10% w/w) and assembled into piles (Unp-10%C). Then, a phyto-cap of Medicago sativa L. either in monoculture (MS-10%C) or co-cropped with Helianthus annuus L. as companion planting (MSHA-10%C) was sown on the topsoil. Physico-chemical parameters and contaminants in the soil and its leachates were measured at the beginning and the end of the first growth season (after five months)...
October 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29047156/cyclophosphamide-induced-male-subfertility-in-mice-an-assessment-of-the-potential-benefits-of-maca-supplement
#10
A Y Onaolapo, B P Oladipo, O J Onaolapo
Effects of Lepidium meyenii (Maca) on cyclophosphamide (CYP)-induced gonadal toxicity in male mice were investigated. Mice were assigned to six treatment groups: Vehicle control, CYP control, CYP plus oral Maca (500 or 1,000 mg/kg), and oral Maca (500 or 1,000 mg/kg). CYP was administered via the intraperitoneal route (days 1-2), while vehicle or Maca were administered daily for 28 days. On day 28, half of the animals in each group were either sacrificed or paired with age-matched females for fertility assessment...
October 18, 2017: Andrologia
https://www.readbyqxmd.com/read/28981578/potassium-not-lepidimoide-is-the-principal-allelochemical-of-cress-seed-exudate-that-promotes-amaranth-hypocotyl-elongation
#11
Stephen C Fry
Background and Aims: Imbibed cress ( Lepidium sativum L.) seeds exude 'allelochemicals' that promote excessive hypocotyl elongation and inhibit root growth in neighbouring competitors, e.g. amaranth ( Amaranthus caudatus L.) seedlings. The major hypocotyl promoter has recently been shown not to be the previously suggested acidic disaccharide, lepidimoic acid (LMA), a fragment of the pectic polysaccharide domain rhamnogalacturonan-I. The nature of the hypocotyl promoter has now been re-assessed...
October 17, 2017: Annals of Botany
https://www.readbyqxmd.com/read/28975545/heterologous-expression-purification-and-characterization-of-a-peroxidase-isolated-from-lepidium-draba
#12
Yaser Fattahian, Ali Riahi-Madvar, Reza Mirzaee, Masoud Torkzadeh-Mahani, Gholamreza Asadikaram
Peroxidase is one of the most widely used enzymes in biotechnology and medicine. In the current study, cDNA encoding peroxidase from Lepidium draba (LDP) was cloned and expressed in Escherichia coli BL21 (DE3) cells in the form of inclusion bodies (IBs). To achieve purified active enzyme, IBs were solubilized before being purified and refolded. The deduced amino acid sequence (308) of the LDP gene (924 bp) revealed 88.96% identity to horseradish peroxidase C1A (HRP C1A). The results of basic local alignment search tool (BLAST) and phylogenetic analysis of the protein sequence showed that this enzyme belongs to the neutral group of class III plant peroxidases...
October 3, 2017: Protein Journal
https://www.readbyqxmd.com/read/28946118/comparative-study-of-eco-and-cytotoxicity-during-biotransformation-of-anthraquinone-dye-alizarin-blue-black-b-in-optimized-cultures-of-microscopic-fungi
#13
Kamila Rybczyńska-Tkaczyk, Agata Święciło, Konrad A Szychowski, Teresa Korniłłowicz-Kowalska
The aim of this study was to select optimal conditions (C and N sources, initial pH and temperature) for biodecolorization of 0.03% anthraquinone dye Alizarin Blue Black B (ABBB) by microscopic fungi: Haematonectria haematococca BwIII43, K37 and Trichoderma harzianum BsIII33. The phenolic compounds, phytotoxicity (Lepidium sativum L.), biotoxicity (Microtox), cytotoxicity and yeast viability assay were performed to determine the extent of ABBB detoxification. Biodecolorization and detoxification of 0.03% ABBB in H...
January 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28903077/assessing-toxicity-of-metal-contaminated-soil-from-glassworks-sites-with-a-battery-of-biotests
#14
M Hagner, M Romantschuk, O-P Penttinen, A Egfors, C Marchand, A Augustsson
The present study addresses toxicological properties of metal contaminated soils, using glassworks sites in south-eastern Sweden as study objects. Soil from five selected glassworks sites as well as from nearby reference areas were analysed for total and water-soluble metal concentrations and general geochemical parameters. A battery of biotests was then applied to assess the toxicity of the glassworks soil environments: a test of phytotoxicity with garden cress (Lepidium sativum); the BioTox™ test for toxicity to bacteria using Vibrio fischeri; and analyses of abundancies and biomass of nematodes and enchytraeids...
February 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/28876077/biomimetic-synthesis-of-macahydantoins-a-and-b-from-lepidium-meyenii-and-structure-revision-of-macahydantoin-b-as-a-class-of-thiohydantoin-with-a-4-methyl-hexahydropyrrolo-1-2-c-imidazole-skeleton
#15
Min Zhou, Hang-Ying Ma, Huan-Huan Xing, Ping Li, Gan-Peng Li, Hui-Chun Geng, Qiu-Fen Hu, Guang-Yu Yang
Phytochemical investigation on Lepidium meyenii led to the discovery of macahydantoin C (3), a new thiohydantoin with a 1,3-diazabicyclo[3.3.1]nonane core, the spectral properties of which indicate a potential structural misassignment of its previously reported analogue, macahydantoin B (2a). To probe this hypothesis, a concise, scalable, and biomimetic synthesis of the originally proposed 2a and its revised structure (2b) was efficiently accomplished using the modified Edman degradation as the key step from commercially available materials in 65% (three steps) and 52% (three steps) overall yields, respectively...
September 6, 2017: Organic Letters
https://www.readbyqxmd.com/read/28846044/red-maca-lepidium-meyenii-a-plant-from-the-peruvian-highlands-promotes-skin-wound-healing-at-sea-level-and-at-high-altitude-in-adult-male-mice
#16
Denisse Nuñez, Paola Olavegoya, Gustavo F Gonzales, Cynthia Gonzales-Castañeda
Nuñez, Denisse, Paola Olavegoya, Gustavo F. Gonzales, and Cynthia Gonzales-Castañeda. Red maca (Lepidium meyenii), a plant from the Peruvian highlands, promotes skin wound healing at sea level and at high altitude in adult male mice. High Alt Med Biol 00:000-000, 2015.-Wound healing consists of three simultaneous phases: inflammation, proliferation, and remodeling. Previous studies suggest that there is a delay in the healing process in high altitude, mainly due to alterations in the inflammatory phase. Maca (Lepidium meyenii) is a Peruvian plant with diverse biological properties, such as the ability to protect the skin from inflammatory lesions caused by ultraviolet radiation, as well as its antioxidant and immunomodulatory properties...
August 28, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28828291/a-novel-in-vitro-transformation-of-lepidium-draba-l-using-rapid-direct-shoot-regeneration
#17
Zahra Zinhari, Shahram Pourseyedi, Jefar Zolalo
The present research is carried out to study Lepidium draba gene transformation for the first time, using direct shoot explants. As a prerequisite for gene transformation, the regeneration conditions in L. draba were optimized. We achieved an efficient and reproducible protocol for successful direct shoot regeneration without intervening callus formation. The results indicate that L. draba is the insistent species of Brassicaceae in direct shoot regeneration. Various explants of L. draba were genetically transformed with different strains of Agrobacterium tumefaciens, viz...
October 2017: 3 Biotech
https://www.readbyqxmd.com/read/28822987/effects-of-a-water-extract-of-lepidium-meyenii-root-in-different-models-of-persistent-pain-in-rats
#18
Barbara Tenci, Lorenzo Di Cesare Mannelli, Mario Maresca, Laura Micheli, Giuseppe Pieraccini, Nadia Mulinacci, Carla Ghelardini
Lepidium meyenii (Walp.), commonly called maca, is an Andean crop belonging to the Brassicaceae family. Maca hypocotils are habitually consumed as customary food as well as traditional remedies for pathological conditions such as infertility. Moreover, the characterization of maca extracts revealed the presence of compounds that are able to modulate the nervous system. Aimed to evaluate the efficacy of L. meyenii in persistent pain, the present study analyzed the effects of a commercial root extract from maca in different animal models reproducing the most common causes of chronic painful pathologies...
October 26, 2017: Zeitschrift Für Naturforschung. C, A Journal of Biosciences
https://www.readbyqxmd.com/read/28811221/is-the-hype-around-the-reproductive-health-claims-of-maca-lepidium-meyenii-walp-justified
#19
REVIEW
Shruti Beharry, Michael Heinrich
ETHNOPHARMACOLOGICAL RELEVANCE: Maca - Lepidium meyenii Walp. has been cultivated and used by Andean people for over 1300-2000 years in Peru as food and medicine. Starting in the late 1990's it has developed into an important herbal medicine in China and is now cultivated there widely, too AIM OF STUDY: This study aims to provide an insight into the emergence of maca on the global market as an alternative remedy to treat reproductive health related problems in both men and women and to critically assess these health claims...
January 30, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28753508/photocatalytic-ozonation-using-doped-tio2-catalysts-for-the-removal-of-parabens-in-water
#20
João F Gomes, Inês Leal, Katarzyna Bednarczyk, Marta Gmurek, Marek Stelmachowski, Magdalena Diak, M Emília Quinta-Ferreira, Raquel Costa, Rosa M Quinta-Ferreira, Rui C Martins
Conventional wastewater treatments are inefficient for the removal of parabens. The aim of this study was finding a suitable solution using ozone and UVA irradiation combined with TiO2 catalysts doped with different noble metals (Ag, Pt, Pd, Au). Photocatalytic ozonation required lower amounts of ozone for higher efficiency on the removal of parabens, chemical oxygen demand (COD) and total organic carbon (TOC). The best catalyst for the initial contaminants degradation was 0.5% Ag-TiO2 leading to total parabens removal using 46mgO3/L...
December 31, 2017: Science of the Total Environment
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