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https://www.readbyqxmd.com/read/29931575/hasta-la-vista-hardcopy-apesm-bids-adieu-to-soft-bound-paper-issues-and-says-ciao-to-on-line-screen-read-e-issues
#1
EDITORIAL
Martin Caon
No abstract text is available yet for this article.
June 21, 2018: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/29913735/looking-at-visceral-pain-new-vistas
#2
Jennifer M A Laird, Fernando Cervero
No abstract text is available yet for this article.
December 29, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/29912425/effects-of-a-saccharomyces-cerevisiae-fermentation-product-in-receiving-diets-of-newly-weaned-beef-steers-i-growth-performance-and-antioxidant-defense
#3
E L Deters, R S Stokes, O N Genther-Schroeder, S L Hansen
To evaluate the effects of a Saccharomyces cerevisiae fermentation product (SCFP; Original XPC, Diamond V, Cedar Rapids, IA) on growth performance and antioxidant defense of newly weaned beef cattle, 180 single-source steers (278 ± 21 kg; SD) were used in a 56-d receiving study. Seven days after arrival, steers were blocked by body weight (BW) to pens of six and randomly assigned to treatments: SCFP at 0 (CON), 14 (SCFP14), or 28 (SCFP28) g·steer-1·d-1. Pen was the experimental unit (n = 10 per treatment)...
June 15, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29912216/-trattamento-del-disturbo-da-uso-di-alcol-da-un-punto-di-vista-psicologico
#4
Giovanna Coriale, Daniela Fiorentino, Francesca De Rosa, Simona Solombrino, Bruna Scalese, Rosaria Ciccarelli, Fabio Attilia, Mario Vitali, Alessia Musetti, Marco Fiore, Mauro Ceccanti
RIASSUNTO. L'elaborazione del piano di trattamento rappresenta un momento molto delicato e complesso del processo terapeutico del disturbo da abuso di alcol (DUA). È la fase in cui le informazioni raccolte da un'équipe di professionisti (medici, psicologi e assistenti sociali) (modello bio-psico-sociale del DUA) vengono messe insieme per decidere il percorso terapeutico più adatto. Per quanto riguarda la parte psicologica, è di notevole importanza scegliere un trattamento clinico in grado di ridurre al minimo la mancata adesione al trattamento e, per i soggetti che rimangono in trattamento, di garantirne l'efficacia...
May 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29912215/-la-diagnosi-del-disturbo-da-uso-di-alcol-dal-punto-di-vista-psicologico
#5
Giovanna Coriale, Daniela Fiorentino, Raffaella Porrari, Gemma Battagliese, Ida Capriglione, Federica Cereatti, Silvia Iannuzzi, Benilde Mauri, Domenica Galli, Marco Fiore, Maria Luisa Attilia, Mauro Ceccanti
RIASSUNTO. Il disturbo da uso di alcol (DUA) è uno dei disturbi psichiatrici più comuni nella popolazione generale. Il DUA è caratterizzato da un pattern di bere eccessivo, che si mantiene nonostante gli effetti negativi che l'alcol ha sul funzionamento lavorativo, sulla salute, sulle problematiche legali, sull'educazione e sulla vita sociale. Attualmente, il modello bio-psico-sociale è quello che spiega meglio il DUA. Infatti, molte ricerche hanno fornito evidenze su come il DUA sia una patologia multidimensionale...
May 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29912214/-trattamento-farmacologico-del-disturbo-da-uso-di-alcol-evidenze-scientifiche
#6
Fabio Attilia, Roberta Perciballi, Claudia Rotondo, Ida Capriglione, Silvia Iannuzzi, Maria Luisa Attilia, Mario Vitali, Giovanni Alessandrini, Maria Concetta Marcella Scamporrino, Marco Fiore, Mauro Ceccanti
RIASSUNTO. La terapia farmacologica nei pazienti con disturbo da uso di alcol riveste un ruolo centrale nel progetto terapeutico, altamente contestualizzato in un approccio multidisciplinare. Sebbene i trattamenti non farmacologici per la dipendenza da alcol risultino ben strutturati e in continua evoluzione, dal punto di vista medico le possibilità di intervento sono realmente ristrette, con poche molecole a disposizione approvate per il disturbo da uso di alcol: nello specifico, l'acamprostato, il naltrexone e, più recentemente, il nalmefene tra gli anticraving; il disulfiram tra gli avversivanti...
May 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29912212/-trattamento-della-dipendenza-da-alcol-alcol-e-giovani-punto-di-vista-sociale
#7
Giovanni Alessandrini, Rosaria Ciccarelli, Gemma Battagliese, Giuseppe Lombardo, Francesca De Rosa, Marisa Patrizia Messina, Mario Vitali, Fabiola Pisciotta, Miriana Nanut, Maria Luisa Attilia, Mauro Ceccanti
RIASSUNTO. Gli adolescenti rappresentano la fascia di età più vulnerabile ai danni causati dall'abuso di alcol, in quanto iniziare a bere in giovane età è associato a un aumento del rischio di dipendenza da alcolici in età adulta. I giovani tendono a bere grandi quantità di alcolici al fine di ricercare forti emozioni e nel tentativo di raggiungere il divertimento a ogni costo, tramite le proprietà psicotrope degli alcolici. Le cause che li inducono ad assumere questi comportamenti sono da ricercare nella non conoscenza degli effetti dannosi dell'alcol, nel rito di convivialità sociale (evenienza per la quale si attribuisce all'alcol la funzione di facilitatore dell'aggregazione tra giovani), nella mancanza di interessi personali, nella scarsità dei controlli e nelle abitudini familiari...
May 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29912211/-trattamento-della-dipendenza-da-alcol-alcol-e-persone-senza-fissa-dimora-punto-di-vista-sociale
#8
Giovanni Alessandrini, Rosaria Ciccarelli, Gemma Battagliese, Federica Cereatti, Simona Gencarelli, Marisa Patrizia Messina, Mario Vitali, Francesca De Rosa, Roberta Ledda, Serena Mancini, Maria Luisa Attilia
RIASSUNTO. Il fenomeno delle persone senza fissa dimora sta assumendo in questi anni una rilevanza sociale devastante, con una prevalenza stimata in USA e in Europa compresa tra il 5,6% e il 13,9%. Queste persone hanno una scarsa qualità di vita, una limitata o assente vita sociale, sono spesso disoccupate o lavorano solo saltuariamente. Sono a rischio di problemi con la legge, sono spesso affette da dipendenza da droghe, da patologie psichiatriche e internistiche. L'alcol spesso non rappresenta la causa della loro condizione sociale, ma solo la conseguenza, contribuendo in questo modo al loro degrado bio-psico-sociale...
May 2018: Rivista di Psichiatria
https://www.readbyqxmd.com/read/29909062/social-touch-a-new-vista-for-developmental-cognitive-neuroscience
#9
EDITORIAL
Teodora Gliga, Teresa Farroni, Carissa J Cascio
No abstract text is available yet for this article.
May 26, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29904961/demography-life-history-and-the-evolution-of-age-dependent-social-behaviour
#10
António M M Rodrigues
Since the inception of modern social evolution theory, a vast majority of studies have sought to explain cooperation using relatedness-driven hypotheses. Natural populations, however, show a substantial amount of variation in social behaviour that is uncorrelated with relatedness. Age offers a major alternative explanation for variation in behaviour that remains unaccounted for. Most natural populations are structured into age-classes, with ageing being a nearly universal feature of most major taxa, including eukaryotic and prokaryotic organisms...
June 14, 2018: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/29898609/verification-study-on-the-norip-ldh-reference-intervals-with-a-proposed-new-upper-reference-limit
#11
Søren Kristiansen, Lennart Friis-Hansen, Claus Antonio Juel Jensen, Steen Ingemann Hansen
We verified the lactate dehydrogenase (LDH) reference interval (RI) provided by the Nordic Reference Interval Project (NORIP). The serum LDH concentration was analysed on the Dimension Vista 1500 system with an IFCC method with a bias of +2.1 % and +2.7 % against NFKK Reference Serum X and ERM-AD453/IFCC, respectively, showing verification of transference of the NORIP RI. Selective data mining in clinical laboratory information systems for retrospective serum LDH test results was used to calculate an indirect RI...
June 13, 2018: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/29890096/alvarado-score-in-the-diagnostic-of-pain-in-the-right-lower-quadrant
#12
Paul Eduardo Lada
BACKGROUND: Acute appendicitis neither suspected nor diagnosed could develop a perforation or otherwise it would take to removing of a normal appendix. OBJECTIVES: Utilization of a clinical score system for aided diagnosis of this pathology and can reduce a negative appendicitis. SETTING: National Clinicas Hospital. Córdoba. Argentina. DESIGN: Prospective and protocolized study. METHODS: 594 patients were studied between October 2002 and December 2013...
September 8, 2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/29887799/non-invasive-brain-stimulation-a-paradigm-shift-in-understanding-brain-oscillations
#13
REVIEW
Johannes Vosskuhl, Daniel Strüber, Christoph S Herrmann
Cognitive neuroscience set out to understand the neural mechanisms underlying cognition. One central question is how oscillatory brain activity relates to cognitive processes. Up to now, most of the evidence supporting this relationship was correlative in nature. This situation changed dramatically with the recent development of non-invasive brain stimulation (NIBS) techniques, which open up new vistas for neuroscience by allowing researchers for the first time to validate their correlational theories by manipulating brain functioning directly...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29879292/the-basal-ganglia-more-than-just-a-switching-device
#14
Tiziana Marilena Florio, Eugenio Scarnati, Ilaria Rosa, Davide Di Censo, Brigida Ranieri, Annamaria Cimini, Angelo Galante, Marcello Alecci
The basal ganglia consist of a variety of subcortical nuclei engaged in motor control and executive functions, such as motor learning, behavioral control, and emotion. The striatum, a major basal ganglia component, is particularly useful for cognitive planning of purposive motor acts owing to its structural features and the neuronal circuitry established with the cerebral cortex. Recent data indicate emergent functions played by the striatum. Indeed, cortico-striatal circuits carrying motor information are paralleled by circuits originating from associative and limbic territories, which are functionally integrated in the striatum...
June 7, 2018: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29873188/new-vistas-on-the-recruiting-of-ferrous-iron-and-dioxygen-by-ferritins-a-case-study-of-the-escherichia-coli-24-mer-ferritin-by-all-atom-molecular-dynamics-in-aqueous-medium
#15
Francesco Pietra
It is shown here that Fe2+ and O2 ligands are displaced from the ferroxidase center of the C1 four-helix bundle of E. coli 24-mer ferritin under molecular dynamics (MD) aided by a randomly oriented external force applied to the ligand. Under these conditions, ligand egress toward the external aqueous medium occurs preferentially from the same four-helix bundle, in case of O2 , or other bundle, in case of Fe2 . Viewing ligand egress from the protein as the microscopic reverse of ligand influx into the protein under unbiased MD, these findings challenge current views that preferential gates for recruitment of Fe2+ are 3-fold channels with human ferritin, or the short path from the ferroxidase center to H93 with bacterial ferritins...
June 5, 2018: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/29860848/immunotherapy-a-glimmer-of-hope-for-metastatic-prostate-cancer
#16
Vishal Jindal
Prostate cancer was the first cancer in which immunotherapy vaccine was approved by FDA in 2010 named Sipuleucel-T. No new immunotherapies have been approved since, as phase 3 trials didn't show any improvement in overall survival (OS) especially with immune checkpoint inhibitors. Currently tremendous amount of research is going on, in studying microenvironment of prostate cancer, finding new targets and biomarkers, and trying different combination therapies. Some of the new targets explored are VISTA and PARP inhibitors...
March 12, 2018: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/29847156/expression-and-phosphorylation-of-stathmin-1-indicate-poor-survival-in-head-and-neck-squamous-cell-carcinoma-and-associate-with-immune-suppression
#17
Hao Wu, Wei-Wei Deng, Lei-Lei Yang, Wen-Feng Zhang, Zhi-Jun Sun
AIM: Immunohistochemistry was used to detect the expression of Stathmin 1 and Serine 38 phospho-Stathmin 1 (p-Stathmin 1S38 ) in head and neck squamous cell carcinoma (HNSCC) and research its correlation with clinical parameters, survival and expression of immune checkpoint molecules. RESULTS: Stathmin 1 and p-Stathmin 1S38 overexpression in primary HNSCC is associated with poor overall survival. Stathmin 1 expression is related to tumor size, category and lymph node status...
May 30, 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29807223/microbiome-as-therapeutics-in-vesicular-delivery
#18
REVIEW
Gautam Singhvi, Vishal Girdhar, Shalini Patil, Gaurav Gupta, Philip M Hansbro, Kamal Dua
Microbiome refers to an ecological community of various symbiotic and pathogenic microorganisms, which plays a crucial role in human health and disease. The concept of novel drug delivery systems particularly the vesicular drug delivery systems is gaining massive attention. This emerging technology has started expanding its horizons in the area of microbiome delivery. This mini-review highlights the role of vesicular systems such as nanoparticles, liposomes etc. as a host/carrier for the microbiome in targeting various diseases...
May 25, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29790613/new-vistas-in-transmetalation-with-discrete-agcf%C3%A2-species-implications-in-pd-mediated-trifluoromethylation-reactions
#19
Monica Helvia Perez-Temprano, Sara Martínez de Salinas, Angel Luis Mudarra, Jordi Benet-Buchholz, Teodor Parella, Feliu Maseras
This work describes the employment of discrete "AgCF₃" complexes, including unique (Cat)[Ag(CF₃)₂] salts, as efficient transmetalating agents to PdII in order to tackle some of the usually overshadowed limitations related to this step within the trifluoromethylation area.
May 23, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29788173/overexpression-of-golgi-phosphoprotein-2-is-associated-with-poor-prognosis-in-oral-squamous-cell-carcinoma
#20
Hao Li, Lei-Lei Yang, Yao Xiao, Wei-Wei Deng, Lei Chen, Lei Wu, Wen-Feng Zhang, Zhi-Jun Sun
Objectives: The aims of this study were to investigate the relationship between Golgi phosphoprotein 2 (GOLPH2) and oral squamous cell carcinoma (OSCC) and explore the clinical significance of GOLPH2 in OSCC. Methods: Tissue microarrays from human OSCC samples were stained for GOLPH2 expression and clinicopathologic features. Kaplan-Meier analysis was used to compare the survival of patients with high GOLPH2 expression and patients with low GOLPH2 expression. Results: We found GOLPH2 is highly expressed in OSCC tissue, and the GOLPH2 expression in metastatic lymph nodes is higher than in tumor tissue...
May 16, 2018: American Journal of Clinical Pathology
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