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https://www.readbyqxmd.com/read/29237860/human-infancy-and-parenting-in-global-perspective-specificity
#1
Marc H Bornstein, Diane L Putnick, Yoonjung Park, Joan T D Suwalsky, O Maurice Haynes
We address three long-standing fundamental questions about early human development and parental caregiving within a specificity framework using data from 796 infant-mother dyads from 11 societies worldwide. Adopting a cross-society view opens a vista on universal biological origins of, and contextual influences on, infant behaviours and parenting practices. We asked: how do infant behaviours and parenting practices vary across societies? How do infant behaviours relate to other infant behaviours, and how do parent practices relate to other parent practices? Are infant behaviours and parent practices related to one another? Behaviours of firstborn five-month infants and parenting practices of their mothers were microanalysed from videorecords of extensive naturally occurring interactions in the home...
December 20, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/29216931/vista-deficiency-attenuates-antibody-induced-arthritis-and-alters-macrophage-gene-expression-in-response-to-simulated-immune-complexes
#2
Sabrina Ceeraz, Susan K Eszterhas, Petra A Sergent, David A Armstrong, Alix Ashare, Thomas Broughton, Li Wang, Dov Pechenick, Christopher M Burns, Randolph J Noelle, Matthew P Vincenti, Roy A Fava
BACKGROUND: In addition to activated T cells, the immune checkpoint inhibitor "V domain-containing Ig suppressor of T-cell activation" (VISTA) is expressed by myeloid cell types, including macrophages and neutrophils. The importance of VISTA expression by myeloid cells to antibody-induced arthritis and its potential for relevance in human disease was evaluated. METHODS: VISTA was immunolocalized in normal and arthritic human synovial tissue sections and synovial tissue lysates were subjected to western blot analysis...
December 8, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29216835/human-t-lymphotropic-virus-1aa-circulation-and-risk-factors-for-sexually-transmitted-infections-in-an-amazon-geographic-area-with-lowest-human-development-index-maraj%C3%A3-island-northern-brazil
#3
Samantha Assis de Aguiar, Samires Avelino de Souza França, Barbara Brasil Santana, Mike Barbosa Santos, Felipe Bonfim Freitas, Glenda Ferreira, Izaura Cayres-Vallinoto, Marluísa O G Ishak, Ricardo Ishak, Antonio Carlos Rosário Vallinoto
BACKGROUND: This cross-sectional study evaluated the prevalence of infection with human T-lymphotropic virus 1 and 2 (HTLV-1 and HTLV-2) in a population from the municipalities of Anajás, Chaves, São Sebastião da Boa Vista (SSBV) and Portel in the Marajó Archipelago and correlated these data with the epidemiological characteristics of the study population. METHODS: A total of 1899 biological samples were evaluated. The samples were screened for the presence of anti-HTLV antibodies using an enzyme-linked immunosorbent assay (ELISA), and infection was confirmed using conventional polymerase chain reaction (PCR), real-time PCR and nucleotide sequencing...
December 8, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29214036/strong-viral-associations-with-sle-among-filipinos
#4
Evan S Vista, Michael H Weisman, Mariko L Ishimori, Hua Chen, Rebecka L Bourn, Ben F Bruner, Laniyati Hamijoyo, Robelle D Tanangunan, Noga J Gal, Julie M Robertson, John B Harley, Joel M Guthridge, Sandra V Navarra, Judith A James
Objectives: Epstein-Barr virus (EBV) is considered an important environmental factor in SLE aetiology, but the relationship between SLE and EBV in the Filipino population is unknown. We tested associations between SLE, lupus-associated autoantibodies and seropositivity for EBV and other herpes viruses in the Filipino population. Methods: Sera from Filipino patients with SLE (n=233), unaffected first-degree relatives (FDRs, n=543) and unrelated controls (n=221) were tested for antibodies against EBV, cytomegalovirus (CMV) and herpes simplex viruses (HSV-1 and HSV-2) by standardised ELISAs...
2017: Lupus Science & Medicine
https://www.readbyqxmd.com/read/29211148/prevalence-of-food-intake-among-individuals-with-hypertension-and-diabetes-in-the-municipality-of-nova-boa-vista-rio-grande-do-sul-brazil-2013
#5
Kelli Destri, Roberta de Vargas Zanini, Maria Cecília Formoso Assunção
OBJECTIVE: to describe the food intake among individuals with high blood pressure and diabetes in a municipality in the south of Brazil. METHODS: a cross-sectional descriptive study was conducted in Nova Boa Vista-RS, Brazil, from June to September 2013; food intake was collected from the questionnaire of the Food and Nutrition Surveillance System (SISVAN) and from an adaptation based on the 2008 Dietary Guidelines for the Brazilian Population. RESULTS: 422 individuals were included in the study (≥18 years old); the food that presented the highest recommended intake frequencies were raw salad (60...
October 2017: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29206195/psychological-distress-and-zika-dengue-and-chikungunya-symptoms-following-the-2016-earthquake-in-bah%C3%A3-a-de-car%C3%A3-quez-ecuador
#6
Anna M Stewart-Ibarra, Anita Hargrave, Avriel Diaz, Aileen Kenneson, David Madden, Moory M Romero, Juan Pablo Molina, David Macias Saltos
On 16 April 2016, a 7.8 magnitude earthquake struck coastal Ecuador, resulting in significant mortality and morbidity, damages to infrastructure, and psychological trauma. This event coincided with the first outbreak of Zika virus (ZIKV) and co-circulation with dengue virus (DENV) and chikungunya virus (CHIKV). We tested whether the degree of psychological distress was associated with the presence of suspected DENV, CHIKV, ZIKV (DCZ) infections three months after the earthquake. In July 2016, 601 household members from four communities in Bahía de Caráquez, Manabí Province, Ecuador, were surveyed in a post-disaster health evaluation...
December 5, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29203588/spatially-resolved-and-quantitative-analysis-of-vista-pd-1h-as-a-novel-immunotherapy-target-in-human-non-small-cell-lung-cancer
#7
Franz Villarroel-Espindola, Xiaoqing Yu, Ila Datar, Nikita Mani, Miguel F Sanmamed, Vamsidhar Velcheti, Konstantinos N Syrigos, Maria I Toki, Hongyu Zhao, Lieping Chen, Roy S Herbst, Kurt A Schalper
PURPOSE: Determine the localized expression pattern and clinical significance of VISTA/PD-1H in human NSCLC. EXPERIMENTAL DESIGN: Using multiplex quantitative immunofluorescence (QIF), we performed localized measurements of VISTA, PD-1 and PD-L1 protein in 758 stage I-IV NSCLCs from 3 independent cohorts represented in tissue microarray format. The targets were selectively measured in cytokeratin+ tumor epithelial cells, CD3+ T-cells, CD4+ T-helper cells, CD8+ cytotoxic T-cells, CD20+ B-lymphocytes and CD68+ tumor-associated macrophages...
December 4, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29202849/designing-healthy-communities-creating-evidence-on-metrics-for-built-environment-features-associated-with-walkable-neighbourhood-activity-centres
#8
Lucy Dubrelle Gunn, Suzanne Mavoa, Claire Boulangé, Paula Hooper, Anne Kavanagh, Billie Giles-Corti
BACKGROUND: Evidence-based metrics are needed to inform urban policy to create healthy walkable communities. Most active living research has developed metrics of the environment around residential addresses, ignoring other important walking locations. Therefore, this study examined: metrics for built environment features surrounding local shopping centres, (known in Melbourne, Australia as neighbourhood activity centres (NACs) which are typically anchored by a supermarket); the association between NACs and transport walking; and, policy compliance for supermarket provision...
December 4, 2017: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/29185224/the-impact-of-hydro-biofuel-wind-energy-consumption-on-environmental-cost-of-doing-business-in-a-panel-of-brics-countries-evidence-from-three-stage-least-squares-estimator
#9
Khalid Zaman
The renewable energy sources are considered the vital factor to promote global green business. The environmental cost of doing business is the pre-requisite to analyze sustainable policies that facilitate the eco-minded entrepreneurs to produce healthier goods. This study examines the impact of renewable energy sources (i.e., hydro energy, biofuel energy, and wind energy) on the environmental cost of doing business in a panel of BRICS (Brazil, Russian Federation, India, China, and South Africa) countries, for the period of 1995-2015...
November 28, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29185148/therapeutic-prospects-of-micrornas-in-cancer-treatment-through-nanotechnology
#10
REVIEW
Rajendra Awasthi, Michael John Rathbone, Philip Michael Hansbro, Mary Bebawy, Kamal Dua
MicroRNAs (miRNAs) represent a new class of diagnostic and prognostic biomarker as well as new therapeutic targets in cancer therapy. miRNAs are gaining significant interest due to extensive advancements in knowledge since their discovery and, more recently, their translational application as therapeutic moieties and targets in the management of disease. miRNAs used in the treatment of cancer would position them as a new class of emerging therapeutic agents. Indeed, numerous candidate miRNAs have been identified as having therapeutic application in the treatment of cancer, but there is still much to learn about how to transform these into effective, patient-compliant, and targeted drug delivery systems...
November 28, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/29182637/local-ecological-knowledge-and-its-relationship-with-biodiversity-conservation-among-two-quilombola-groups-living-in-the-atlantic-rainforest-brazil
#11
Bruno Esteves Conde, Tamara Ticktin, Amanda Surerus Fonseca, Arthur Ladeira Macedo, Timothy Ongaro Orsi, Luciana Moreira Chedier, Eliana Rodrigues, Daniel Sales Pimenta
Information on the knowledge, uses, and abundance of natural resources in local communities can provide insight on conservation status and conservation strategies in these locations. The aim of this research was to evaluate the uses, knowledge and conservation status of plants in two Quilombolas (descendants of slaves of African origin) communities in the Atlantic rainforest of Brazil, São Sebastião da Boa Vista (SSBV) and São Bento (SB). We used a combination of ethnobotanical and ecological survey methods to ask: 1) What ethnobotanical knowledge do the communities hold? 2) What native species are most valuable to them? 3) What is the conservation status of the native species used? Thirteen local experts described the names and uses of 212 species in SSBV (105 native species) and 221 in SB (96 native species)...
2017: PloS One
https://www.readbyqxmd.com/read/29174732/disinhibition-in-learning-and-memory-circuits-new-vistas-for-somatostatin-interneurons-and-long-term-synaptic-plasticity
#12
REVIEW
Julien Artinian, Jean-Claude Lacaille
Neural circuit functions involve finely controlled excitation/inhibition interactions that allow complex neuronal computations and support high order brain functions such as learning and memory. Disinhibition, defined as a transient brake on inhibition that favors excitation, recently appeared to be a conserved circuit mechanism implicated in various functions such as sensory processing, learning and memory. Although vasoactive intestinal polypeptide (VIP) interneurons are considered to be the main disinhibitory cells, recent studies highlighted a pivotal role of somatostatin (SOM) interneurons in inhibiting GABAergic interneurons and promoting principal cell activation...
November 22, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/29165060/relationship-between-race-and-outcome-in-asian-black-and-caucasian-patients-with-spontaneous-intracerebral-hemorrhage-data-from-the-virtual-international-stroke-trials-archive-and-efficacy-of-nitric-oxide-in-stroke-trial
#13
Kailash Krishnan, Lucy Beishon, Eivind Berge, Hanne Christensen, Robert A Dineen, Serefnur Ozturk, Nikola Sprigg, Joanna M Wardlaw, Philip M Bath
Background and purpose Although poor prognosis after intracerebral hemorrhage relates to risk factors and hematoma characteristics, there is limited evidence for the effect of race-ethnicity. Methods Data from 1011 patients with intracerebral hemorrhage enrolled into hyperacute trials and randomized to control were obtained from the Virtual International Stroke Trials Archive and Efficacy of Nitric Oxide in Stroke Trial. Clinical characteristics and functional outcome were compared among three racial groups - Asians, Blacks, and Caucasians...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29160705/h-x-x-h-ch3-ch2f-chf2-cf3-and-sih3-bond-activation-by-criegee-intermediates-a-theoretical-perspective
#14
Manoj Kumar, Joseph S Francisco
Using theoretical calculations and Born Oppenheimer molecular dynamics simulations, it is shown here that Criegee intermediate, which is principally produced in the olefin ozonolysis, can activate H-X (X = H, CH3, CH2F, CHF2, CF3, and SiH3) under mild conditions, a reaction that has long been known for transition metals. The zwitter ionic electronic structure of Criegee intermediate makes it an interesting metal-free system for activating enthalpically strong small molecules such as H2, methane, silanes, and boranes...
November 21, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29134925/effects-of-ssri-exposure-on-hemorrhagic-complications-and-outcome-following-thrombolysis-in-ischemic-stroke
#15
Schellen Christoph, Ferrari Julia, Lang Wilfried, Sykora Marek
Background Selective serotonin reuptake inhibitors (SSRI) may interfere with platelet function, and pre-stroke SSRI treatment has been associated with increased hematoma volumes and mortality in hemorrhagic stroke patients. The effects of SSRI on the risk of hemorrhagic complications after thrombolysis in ischemic stroke patients are unclear. Aims To examine the effects of pre-stroke SSRI exposure on bleeding complications, functional outcome, and mortality following thrombolysis in ischemic stroke. Methods Data including standard demographic and clinical variables as well as baseline and follow-up stroke severity (measured by National Institutes of Health Stroke Score), functional outcome (measured by modified Rankin Scale) at 3 months, and mortality at 7 and 90 days were extracted from the Virtual International Stroke Trials Archive...
January 1, 2017: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/29134135/polypoidal-choroidal-vasculopathy-on-swept-source-optical-coherence-tomography-angiography-with-variable-interscan-time-analysis
#16
Carl B Rebhun, Eric M Moult, Eduardo A Novais, Carlos Moreira-Neto, Stefan B Ploner, Ricardo N Louzada, ByungKun Lee, Caroline R Baumal, James G Fujimoto, Jay S Duker, Nadia K Waheed, Daniela Ferrara
Purpose: To use a novel optical coherence tomography angiography (OCTA) algorithm termed variable interscan time analysis (VISTA) to evaluate relative blood flow speeds in polypoidal choroidal vasculopathy (PCV). Methods: Prospective cross-sectional study enrolling patients with confirmed diagnosis of PCV. OCTA of the retina and choroid was obtained with a prototype swept-source OCT system. The acquired OCT volumes were centered on the branching vascular network (BVN) and polyps as determined by indocyanine-green angiography (ICGA)...
November 2017: Translational Vision Science & Technology
https://www.readbyqxmd.com/read/29130062/human-spatial-navigation-representations-across-dimensions-and-scales
#17
Arne D Ekstrom, Eve A Isham
Humans, like many other species, employ three fundamental forms of strategies to navigate: allocentric, egocentric, and beacon. Here, we review each of these different forms of navigation with a particular focus on how our high-resolution visual system contributes to their unique properties. We also consider how we might employ allocentric and egocentric representations, in particular, across different spatial dimensions, such as 1-D vs. 2-D. Our high acuity visual system also leads to important considerations regarding the scale of space we are navigating (e...
October 2017: Current Opinion in Behavioral Sciences
https://www.readbyqxmd.com/read/29125387/significado-de-psic%C3%A3-logas-os-de-atenci%C3%A3-n-primaria-de-salud-sobre-la-intervenci%C3%A3-n-psicosocial-de-grupo-en-el-tratamiento-de-la-depresi%C3%A3-n-en-chile
#18
Gonzalo Andrade, Adriana Espinoza
En Chile, el tratamiento de la depresión en salud pública promueve la realización de Intervenciones Psicosociales en Grupo (IPG) para todos los casos diagnosticados, no obstante, se observa una baja implementación de estas prestaciones. El presente artículo describe y caracteriza, desde el punto de vista de la disciplina psicológica, el significado de psicólogas/os que trabajan en consultorios de atención primaria de salud (APS) sobre las IPG en el tratamiento de la depresión. Se entrevistaron a ocho psicólogas/os de los distintos Servicios de Salud de la Región Metropolitana de Santiago...
November 1, 2017: Global Health Promotion
https://www.readbyqxmd.com/read/29125159/development-of-luminescent-sensors-based-on-transition-metal-complexes-for-the-detection-of-nitroexplosives
#19
Veerasamy Sathish, Arumugam Ramdass, Murugesan Velayudham, Kuang-Lieh Lu, Pounraj Thanasekaran, Seenivasan Rajagopal
The detection of chemical explosives is a major area of research interest and is essential for the military as well as homeland security to counter the catastrophic effects of global terrorism. In recent years, tremendous effort has been devoted to the development of luminescent materials for the detection of explosives in the vapor, solution, and solid states with a high degree of selectivity and sensitivity and a rapid response time. Apart from the wide range of organic fluorescent chemosensors, transition metal complexes play a prominent role in the sensing of nitroaromatic explosives owing to their rich photophysical characteristics...
November 10, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29119388/potentialities-of-microrna-diagnosis-in-patients-with-bladder-cancer
#20
P V Shegay, A A Zhavoronkov, N M Gaifullin, N V Vorob'ev, B Ya Alekseev, S V Popov, A V Garazha, A A Buzdin, A D Kaprin
Despite promising vista of the use of microRNA in molecular diagnosis of bladder cancer, there are few data on their expression profiles, which impedes assessment of diagnostic value of these marker molecules. In this study, suppression subtractive hybridization, on-chip hybridization, and high-throughput deep sequencing focused on profiling microRNA and assessing the diagnostic value of revealed marker molecules.
November 9, 2017: Bulletin of Experimental Biology and Medicine
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