Read by QxMD icon Read


Jean Shaw
No abstract text is available yet for this article.
January 2017: Ophthalmology
Wen-Fei Tan, Zhi-Lin Wang, Hong Ma, Feng Jin, Huang-Wei Lu
Despite major advances in anesthesia management and developments in anesthetic agents, postoperative sleep disturbances remain dissatisfactory for many patients. We hypothesized that propofol might have a subtle influence on sleep after thyroidectomy compared to sevoflurane. A randomized, single-blinded, controlled trial was conducted at the First Hospital of China Medical University from October 2014 to October 2015. One hundred and twenty-four patients undergoing thyroidectomy were enrolled and received sevoflurane (sevoflurane group) or propofol (propofol group) as anesthesia maintenance...
January 12, 2017: Journal of Clinical Monitoring and Computing
Marcelo A Pinto, Jair G da Silva, Aljamir D Chedid, Marcio F Chedid
Introduction: Use of tranexamic acid (TXA) in trauma has been the subject of growing interest by researchers and health professionals. However, there are still several open questions regarding its use. In some aspects medical literature is controversial. The points of disagreement among experts include questions such as: Which patients should receive TXA in trauma? Should treatment be performed in the pre-hospital environment? Is there any need for laboratory parameters before starting TXA treatment? What is the drug safety profile? The main issue on which there is still no basis in literature is: What is the indication for treatment within massive transfusion protocols? Objective: Answer the questions proposed based on critical evaluation of the evidence gathered so far and carry out a study of cost-effectiveness of TXA use in trauma adapted to the Brazilian reality...
November 2016: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
Jennifer H Garvin, Megha Kalsy, Cynthia Brandt, Stephen L Luther, Guy Divita, Gregory Coronado, Doug Redd, Carrie Christensen, Brent Hill, Natalie Kelly, Qing Zeng Treitler
In an ideal clinical Natural Language Processing (NLP) ecosystem, researchers and developers would be able to collaborate with others, undertake validation of NLP systems, components, and related resources, and disseminate them. We captured requirements and formative evaluation data from the Veterans Affairs (VA) Clinical NLP Ecosystem stakeholders using semi-structured interviews and meeting discussions. We developed a coding rubric to code interviews. We assessed inter-coder reliability using percent agreement and the kappa statistic...
February 2017: Journal of Medical Systems
Sarah Bastawrous, Benjamin Carney
In the current digital and filmless age of radiology, rates of unread radiology exams remain low, however, may still exist in unique environments. Veterans Affairs (VA) health care systems may experience higher rates of unread exams due to coexistence of Veterans Health Information Systems and Technology Architecture (VistA) imaging and commercial picture archiving and communication systems (PACS). The purpose of this patient safety initiative was to identify any unread exams and causes leading to unread exams...
January 3, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
T Giaddui, N Li, K Curry, K Moore, L Mell, C Leath, C Kunos, Y Xiao
PURPOSE: To establish a workflow for NRG-GY006 IMRT pre-treatment reviews, incorporating advanced radiotherapy technologies being evaluated as part of the clinical trial. METHODS: Pre-Treatment reviews are required for every IMRT case as part of NRG-GY006 (a randomized phase II trial of radiation therapy and cisplatin alone or in combination with intravenous triapine in women with newly diagnosed bulky stage I B2, stage II, IIIB, or IVA cancer of the uterine cervix or stage II-IVA vaginal cancer...
June 2016: Medical Physics
C Ma, Y Yin
PURPOSE: The purpose of this research is investigating which texture features extracted from FDG-PET images by gray-level co-occurrence matrix(GLCM) have a higher prognostic value than the other texture features. METHODS: 21 non-small cell lung cancer(NSCLC) patients were approved in the study. Patients underwent 18F-FDG PET/CT scans with both pre-treatment and post-treatment. Firstly, the tumors were extracted by our house developed software. Secondly, the clinical features including the maximum SUV and tumor volume were extracted by MIM vista software, and texture features including angular second moment, contrast, inverse different moment, entropy and correlation were extracted using MATLAB...
June 2016: Medical Physics
Miguel Ayán-Varela, Óscar Pérez-Vidal, Juan I Paredes, José M Munuera, Silvia Villar-Rodil, María Díaz-González, César Fernández-Sánchez, Virgilia S Silva, Mónica Cicuéndez, Mercedes Vila, Amelia Martínez-Alonso, Juan M D Tascón
The exfoliation and colloidal stabilization of layered transition metal dichalcogenides (TMDs) in an aqueous medium using functional biomolecules as dispersing agents have a number of potential benefits toward the production and practical use of the corresponding two-dimensional materials, but such a strategy has so far remained underexplored. Here, we report that DNA and RNA nucleotides are highly efficient dispersants in the preparation of stable aqueous suspensions of MoS2 and other TMD nanosheets at significant concentrations (up to 5-10 mg mL(-1))...
January 11, 2017: ACS Applied Materials & Interfaces
Christian Hametner, Rachael L MacIsaac, Lars Kellert, Azmil H Abdul-Rahim, Peter A Ringleb, Kennedy R Lees
BACKGROUND AND PURPOSE: We hypothesized that any sex-related difference in outcome poststroke is explained by other prognostic factors and that the response to intravenous recombinant tissue-type plasminogen activator (r-tPA) is equal in males and females after adjustment for such factors. METHODS: We accessed an independent collection of randomized clinical trials-the VISTA (Virtual International Stroke Trials Archive). Data were preprocessed by selecting complete cases (n=8028) and matching females to males (coarsened exact matching, n=4575, 24...
December 27, 2016: Stroke; a Journal of Cerebral Circulation
Koichi Takano, Kosuke Hida, Yasuo Kuwabara, Kengo Yoshimitsu
PURPOSE: We investigated the enhancement of the intracranial arterial walls with gadolinium-enhanced, black-blood three-dimensional T1-weighted imaging (Gd-3DBB) by using an improved motion-sensitized driven-equilibrium (iMSDE)-prepared volumetric isotropic turbo spin-echo acquisition (VISTA). METHODS: A total of 115 patients underwent FLAIR, 3D-TOF-MRA and Gd-3DBB with a 1.5-T scanner. The degree and distribution of the arterial wall enhancement on Gd-3DBB was assessed...
January 2017: European Journal of Radiology
Ingrid N G Rosário, Andrey J Andrade, Raphael Ligeiro, Ricardo Ishak, Ivoneide M Silva
Phlebotomines (Diptera: Psychodidae) are vectors of several etiological agents of human and animal diseases, including protozoans of the gender Leishmania Precarious socioeconomic conditions and uncontrolled population growth directly influence the transmission risk of parasites and the urbanization of vector species, previously restricted to wild environments. The Marajó Archipelago is considered a high incidence area of leishmaniasis in the Brazilian Amazon. However, it is poorly studied. The aim of this study was to assess the adaptation processes of phlebotomine species to anthropized environments in this region...
December 22, 2016: Journal of Medical Entomology
Charles C Wykoff, Dennis M Marcus, Edoardo Midena, Jean-François Korobelnik, Namrata Saroj, Andrea Gibson, Robert Vitti, Alyson J Berliner, Zinaria Williams Liu, Oliver Zeitz, Carola Metzig, Thomas Schmelter, Jeffrey S Heier
Importance: Information on the effect of anti-vascular endothelial growth factor therapy in eyes with diabetic macular edema (DME) with vision loss after macular laser photocoagulation is clinically valuable. Objective: To evaluate visual and anatomic outcomes in a subgroup of macular laser photocoagulation treatment control (hereafter laser control) eyes with substantial vision loss receiving treatment with intravitreal aflibercept injection. Design, Setting, and Participants: This investigation was a post hoc analysis of a subgroup of laser control eyes in 2 phase 3 trials-VISTA (Study of Intravitreal Aflibercept Injection in Patients With Diabetic Macular Edema) and VIVID (Intravitreal Aflibercept Injection in Vision Impairment Due to DME)-in a multicenter setting...
December 22, 2016: JAMA Ophthalmology
Stefan B Ploner, Eric M Moult, WooJhon Choi, Nadia K Waheed, ByungKun Lee, Eduardo A Novais, Emily D Cole, Benjamin Potsaid, Lennart Husvogt, Julia Schottenhamml, Andreas Maier, Philip J Rosenfeld, Jay S Duker, Joachim Hornegger, James G Fujimoto
PURPOSE: Currently available optical coherence tomography angiography systems provide information about blood flux but only limited information about blood flow speed. The authors develop a method for mapping the previously proposed variable interscan time analysis (VISTA) algorithm into a color display that encodes relative blood flow speed. METHODS: Optical coherence tomography angiography was performed with a 1,050 nm, 400 kHz A-scan rate, swept source optical coherence tomography system using a 5 repeated B-scan protocol...
December 2016: Retina
Eric M Moult, Nadia K Waheed, Eduardo A Novais, WooJhon Choi, ByungKun Lee, Stefan B Ploner, Emily D Cole, Ricardo N Louzada, Chen D Lu, Philip J Rosenfeld, Jay S Duker, James G Fujimoto
PURPOSE: To investigate choriocapillaris (CC) alteration in patients with nascent geographic atrophy (nGA) and/or drusen-associated geographic atrophy (DAGA) using swept-source optical coherence tomography angiography (OCTA). METHODS: A 1,050-nm wavelength, 400 kHz A-scan rate swept-source optical coherence tomography prototype was used to perform volumetric swept-source optical coherence tomography angiography over 6 mm × 6 mm fields of view in patients with nGA and/or DAGA...
December 2016: Retina
Sabrina Ceeraz, Petra A Sergent, Sean F Plummer, Alan R Schned, Dov Pechenick, Christopher M Burns, Randolph J Noelle
OBJECTIVES: The targeting of negative checkpoint regulators (NCRs) as a means of augmenting anti-tumor immune responses is now an increasingly utilized and remarkably effective approach to the treatment of several human malignancies. The NCR VISTA (V-domain Ig suppressor of T cell activation, PD-1H, DD1α) suppresses T cell responses and regulates myeloid activities. We proposed that exploitation of the VISTA pathway is a novel strategy for the treatment of human autoimmune disease and therefore studied the impact of VISTA genetic deficiency on lupus development in a lupus-prone mouse strain...
December 19, 2016: Arthritis & Rheumatology
Mohinish G Bhatjiwale, Mrudul M Bhatjiwale, Ami Bhagat
BACKGROUND: Pulsed radiofrequency although present for many years has been used little compared to ablative procedures for pain relief. Its use in trigeminal neuralgia is sparse and unreported in the ophthalmic division, where the possibility of sensory loss can lead to high morbidity. We wished to explore the potential of this reportedly safe modality for a prolonged duration in a highly sensitive anatomic neural location, however, in a very secure, structured, and staged manner. CASE DESCRIPTION: A patient suffering from ophthalmic division (V1) medically uncontrolled neuralgia with a preoperative visual analog scale (VAS) score of 9/10 was subjected to a percutaneous pain relief procedure...
2016: Surgical Neurology International
Vikrant Dilip Sane, Sanjay Chandan, Sujay Patil, Krishna Patil
As dentistry continues to go "digital," the field has seen a phenomenal increase in the use of digital imaging in dental practice. Complex impacted mesiodens present potential treatment complications and sometimes possible patient morbidity. Objectives of diagnostic imaging are to aid in diagnosis, decision making, and enhance treatment outcomes. As cases become more complex, sophisticated multiplane imaging methods allowing for a three-dimensional view are more likely to meet these objectives as opposed to traditional two-dimensional radiography...
December 14, 2016: Journal of Craniofacial Surgery
Daisuke Ogiya, Hirohiko Shibayama, Eiji Nakatani, Kiyoshi Ando, Kenshi Suzuki, Yoshiaki Kuroda, Toshiki Uchida, Dai Maruyama, Morio Matsumoto, Kosei Matsue, Shinsuke Iida, Yasuhito Terui, Masaki Ri, Takaaki Chou, Nobuyuki Aotsuka, Sumie Tabata, Jun Konishi, Kazuteru Ohashi, Atsushi Shinagawa, Isamu Sugiura, Junya Kuroda, Toshihiro Miyamoto, Michinori Ogura, Kensei Tobinai, Yuzuru Kanakura, Tomomitsu Hotta
The phase I/II study of melphalan-prednisolone-bortezomib (MPB) therapy in Japanese patients with previously untreated multiple myeloma (MM) who are ineligible for hematopoietic stem cell transplantation (JPN-102 trial) (registered between July 2008 and March 2011) showed an overall response rate in the MPB arm equivalent to that of the VISTA trial. In this study, we followed up the clinical data of 92 of the 101 patients registered in the JPN-102 trial to clarify the long-term outcomes of MPB therapy. The median follow-up period was 50...
2016: [Rinshō Ketsueki] the Japanese Journal of Clinical Hematology
Kamal Dua, Shakti D Shukla, Rakesh K Tekade, Philip M Hansbro
Biofilm comprises a community of microorganisms which form on medical devices and can lead to various threatening infections. It is a major concern in various respiratory diseases like cystic fibrosis, chronic obstructive pulmonary disease, etc. The treatment strategies for such infections are difficult due to the resistance of the microflora existing in the biofilms against various antimicrobial agents, thus posing threats to the patient population. The present era witnesses the beginning of research to understand the biofilm physiology and the associated microfloral diversity by applying -omics approaches...
December 6, 2016: Drug Delivery and Translational Research
Nickolas M Jones, Sean P Wojcik, Josiah Sweeting, Roxane Cohen Silver
Studying communities impacted by traumatic events is often costly, requires swift action to enter the field when disaster strikes, and may be invasive for some traumatized respondents. Typically, individuals are studied after the traumatic event with no baseline data against which to compare their postdisaster responses. Given these challenges, we used longitudinal Twitter data across 3 case studies to examine the impact of violence near or on college campuses in the communities of Isla Vista, CA, Flagstaff, AZ, and Roseburg, OR, compared with control communities, between 2014 and 2015...
December 2016: Psychological Methods
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"