keyword
MENU ▼
Read by QxMD icon Read
search

Nelson

keyword
https://www.readbyqxmd.com/read/29222981/fabrication-of-biocompatible-and-efficient-antimicrobial-porous-polymer-surfaces-by-the-breath-figures-approach
#1
Nelson Vargas-Alfredo, Enrique Martínez-Campos, Ana Santos-Coquillat, Ane Dorronsoro, Aitziber L Cortajarena, Adolfo Del Campo, Juan Rodríguez-Hernández
We designed and fabricated highly efficient and selective antibacterial substrates, i.e. surface non-cytotoxic against mammalian cells but exhibiting strong antibacterial activity. For that purpose, microporous substrates (pore sizes in the range of 3-5 μm) were fabricated using the Breath Figures approach (BFs). These substrates have additionally a defined chemical composition in the pore cavity (herein either a poly(acrylic acid) or the antimicrobial peptide Nisin) while the composition of the rest of the surface is identical to the polymer matrix...
November 20, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29222454/stromal-versican-regulates-tumor-growth-by-promoting-angiogenesis
#2
Keiichi Asano, Courtney M Nelson, Sumeda Nandadasa, Noriko Aramaki-Hattori, Daniel J Lindner, Tyler Alban, Junko Inagaki, Takashi Ohtsuki, Toshitaka Oohashi, Suneel S Apte, Satoshi Hirohata
The proteoglycan versican is implicated in growth and metastases of several cancers. Here we investigated a potential contribution of stromal versican to tumor growth and angiogenesis. We initially determined versican expression by several cancer cell lines. Among these, MDA-MB231 and B16F10 had none to minimal expression in contrast to Lewis lung carcinoma (LLC). Notably, tumors arising from these cell lines had higher versican levels than the cell lines themselves suggesting a contribution from the host-derived tumor stroma...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29221617/minor-procedure-major-impact-patient-reported-outcomes-following-urethral-meatotomy
#3
Briony K Varda, Tanya Logvinenko, Stuart Bauer, Bartley Cilento, Richard N Yu, Caleb P Nelson
INTRODUCTION: Urethral meatotomy as treatment for meatal stenosis is a common pediatric urology procedure; however, little is known about the patient experience following this procedure. OBJECTIVE: We aim to evaluate clinical factors associated with patient-reported symptom improvement after urethral meatotomy. STUDY DESIGN: The families of boys undergoing urethral meatotomy between 2/2013 and 8/2016 received a survey by mail 6 weeks after surgery...
November 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29221498/influence-of-community-based-education-on-undergraduate-health-professions-students-decision-to-work-in-underserved-areas-in-uganda
#4
Samuel Kizito, Rhona Baingana, Kintu Mugagga, Peter Akera, Nelson K Sewankambo
BACKGROUND: Uganda is beset by a shortage of health workers and the few available are mal-distributed. Providing rural exposure through community-based education could positively influence students' perspectives towards work in rural areas. We aimed to assess the impact of Community-Based Education and Research (COBERS) on health professions students' attitudes towards working in rural areas. This was a before-and-after study among 525 students of 4 medical universities in Uganda. Data was collected using self-administered paper-based questionnaires...
December 8, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29221283/effectiveness-and-safety-of-simultaneous-hybrid-thoracoscopic-endocardial-catheter-ablation-of-atrial-fibrillation-in-obese-and-non-obese-patients
#5
Kevin Phan, Laurent Pison, Nelson Wang, Aran Kanagaratnam, Tristan D Yan, Bart Maesen, Jos G Maessen, Harry J Crijns, Mark La Meir
Background: We evaluated the safety and effectiveness of the hybrid thoracoscopic endocardial epicardial ablation technique for the treatment of atrial fibrillation (AF) in obese versus non-obese patients. Methods: Between January 2010 and January 2015, a cohort of 61 patients were retrospectively identified to undergo ablation of AF as a stand-alone procedure using a thoracoscopic, hybrid epicardial-endocardial technique. All patients underwent continuous 7-day Holter monitoring at 3, 6 months, 1 year and yearly thereafter...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29220441/improved-annotation-of-the-insect-vector-of-citrus-greening-disease-biocuration-by-a-diverse-genomics-community
#6
Surya Saha, Prashant S Hosmani, Krystal Villalobos-Ayala, Sherry Miller, Teresa Shippy, Mirella Flores, Andrew Rosendale, Chris Cordola, Tracey Bell, Hannah Mann, Gabe DeAvila, Daniel DeAvila, Zachary Moore, Kyle Buller, Kathryn Ciolkevich, Samantha Nandyal, Robert Mahoney, Joshua Van Voorhis, Megan Dunlevy, David Farrow, David Hunter, Taylar Morgan, Kayla Shore, Victoria Guzman, Allison Izsak, Danielle E Dixon, Andrew Cridge, Liliana Cano, Xiaolong Cao, Haobo Jiang, Nan Leng, Shannon Johnson, Brandi L Cantarel, Stephen Richards, Adam English, Robert G Shatters, Chris Childers, Mei-Ju Chen, Wayne Hunter, Michelle Cilia, Lukas A Mueller, Monica Munoz-Torres, David Nelson, Monica F Poelchau, Joshua B Benoit, Helen Wiersma-Koch, Tom D'Elia, Susan J Brown
https://citrusgreening.org/.
January 1, 2017: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/29219908/characteristics-of-the-nursing-practice-environment-associated-with-lower-unit-level-rn-turnover
#7
Heather V Nelson-Brantley, Shin Hye Park, Sandra Bergquist-Beringer
OBJECTIVE: The aim of this study is to examine characteristics of the nursing practice environment associated with lower RN turnover. BACKGROUND: Identifying characteristics of the practice environment that contribute to lower RN turnover is important for meeting the national quality strategy priority of reducing healthcare costs. METHODS: Data from 1002 adult care units in 162 National Database of Nursing Quality Indicators participating hospitals were analyzed using multivariate linear regression...
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29218821/activity-dependent-control-of-nmda-receptor-subunit-composition-at-hippocampal-mossy-fibre-synapses
#8
Mario Carta, Bettadapura N Srikumar, Adam Gorlewicz, Nelson Rebola, Christophe Mulle
Single neurons express NMDARs with distinct subunit composition and biophysical properties which can be segregated in an input-specific manner. The dynamic control of the heterogeneous distribution of synaptic NMDARs is crucial to control input-dependent synaptic integration and plasticity. In hippocampal CA3 pyramidal cells (CA3 PCs) from mice of both sexes, we found that mossy fibre (Mf) synapses display a markedly lower proportion of GluN2B containing NMDARs than associative/commissural synapses. The mechanism involved in such heterogeneous distribution of GluN2B subunits is not known...
December 7, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/29218388/correlation-of-sociodemographic-and-clinical-parameters-with-depression-and-distress-in-patients-with-hematologic-malignancies
#9
Amanda J Shreders, Shehzad K Niazi, David O Hodge, Nicolette T Chimato, Megha Kureti, Navya Kirla, Ankit Agrawal, Abhisek Swaika, Elaine Gustetic, Renee Foster, Kimberly A Nelson, Prachi Jani, Asher A Chanan-Khan, Sikander Ailawadhi
A quarter of cancer patients struggle with distress or depression during their illness. Multiple organizations including the National Comprehensive Cancer Network recommend universal screening for distress and depression. Herein, we describe a universal screening program in patients with hematologic malignancies and factors associated with distress and depression. Between December 2013 and February 2015, patients with hematologic malignancies took the Patient Health Questionnaire 9 (PHQ-9) and Distress Thermometer (DT) prior to receiving their first outpatient parenteral chemotherapy...
December 7, 2017: Annals of Hematology
https://www.readbyqxmd.com/read/29217731/genome-wide-analysis-of-grain-yield-stability-and-environmental-interactions-in-a-multiparental-soybean-population
#10
Alencar Xavier, Diego Jarquin, Reka Howard, Vishnu Ramasubramanian, James E Specht, George L Graef, William D Beavis, Brian W Diers, Qijian Song, Perry Cregan, Randall Nelson, Rouf Mian, J G Shannon, Leah McHale, Dechun Wang, William Schapaugh, Aaron J Lorenz, Shizhong Xu, William Muir, Katy M Rainey
Genetic improvement towards optimized and stable agronomic performance of soybean genotypes is desirable for food security. Understanding how genotypes perform in different environmental conditions helps breeders develop sustainable cultivars adapted to target regions. Complex traits of importance are known to be controlled by a large number of genomic regions with small effects whose magnitude and direction are modulated by environmental factors. Knowledge of the constraints and undesirable effects resulting from genotype by environmental interactions is a key objective in improving selection procedures in soybean breeding programs...
December 7, 2017: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/29217375/preliminary-aggregate-safety-and-immunogenicity-results-from-three-trials-of-a-purified-inactivated-zika-virus-vaccine-candidate-phase-1-randomised-double-blind-placebo-controlled-clinical-trials
#11
Kayvon Modjarrad, Leyi Lin, Sarah L George, Kathryn E Stephenson, Kenneth H Eckels, Rafael A De La Barrera, Richard G Jarman, Erica Sondergaard, Janice Tennant, Jessica L Ansel, Kristin Mills, Michael Koren, Merlin L Robb, Jill Barrett, Jason Thompson, Alison E Kosel, Peter Dawson, Andrew Hale, C Sabrina Tan, Stephen R Walsh, Keith E Meyer, James Brien, Trevor A Crowell, Azra Blazevic, Karla Mosby, Rafael A Larocca, Peter Abbink, Michael Boyd, Christine A Bricault, Michael S Seaman, Anne Basil, Melissa Walsh, Veronica Tonwe, Daniel F Hoft, Stephen J Thomas, Dan H Barouch, Nelson L Michael
BACKGROUND: A safe, effective, and rapidly scalable vaccine against Zika virus infection is needed. We developed a purified formalin-inactivated Zika virus vaccine (ZPIV) candidate that showed protection in mice and non-human primates against viraemia after Zika virus challenge. Here we present the preliminary results in human beings. METHODS: We did three phase 1, placebo-controlled, double-blind trials of ZPIV with aluminium hydroxide adjuvant. In all three studies, healthy adults were randomly assigned by a computer-generated list to receive 5 μg ZPIV or saline placebo, in a ratio of 4:1 at Walter Reed Army Institute of Research, Silver Spring, MD, USA, or of 5:1 at Saint Louis University, Saint Louis, MO, USA, and Beth Israel Deaconess Medical Center, Boston, MA, USA...
December 4, 2017: Lancet
https://www.readbyqxmd.com/read/29216029/disparities-in-hospital-reported-breast-milk-use-in-neonatal-intensive-care-units-united-states-2015
#12
Ellen O Boundy, Cria G Perrine, Jennifer M Nelson, Heather C Hamner
Breast milk is the recommended nutrition for infants. For preterm infants, when mother's milk is not available, pasteurized donor milk is recommended (1). Non-Hispanic black mothers are at increased risk for having a preterm birth and for not breastfeeding (2,3); however, it is not known whether demographic disparities exist in the use of breast milk in neonatal intensive care units (NICUs). Data from CDC's 2015 Maternity Practices in Infant Nutrition and Care (mPINC) survey, which does not collect patient-level demographics, were linked to the 2011-2015 U...
December 8, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29215901/introduction-of-the-dsm-5-levels-of-personality-functioning-questionnaire
#13
Steven K Huprich, Sharon M Nelson, Kevin B Meehan, Caleb J Siefert, Gregory Haggerty, James Sexton, V Barry Dauphin, Matthew Macaluso, Jennifer Jackson, Rosey Zackula, Lyle Baade
With the introduction in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) of a hybrid system of personality disorder assessment, the ability to assess patients' traits, as well as their level of personality functioning, has become increasingly important. To assess this criterion, the DSM-5 Levels of Personality Functioning Questionnaire (DLOPFQ) was developed. The DLOPFQ assesses individuals' self-impairments and other impairments in several domains (self-direction, identity, empathy, and intimacy) and across 2 contexts (work/school and relationships)...
December 7, 2017: Personality Disorders
https://www.readbyqxmd.com/read/29215479/major-abdominal-and-perianal-surgery-in-crohn-s-disease-long-term-follow-up-of-australian-patients-with-crohn-s-disease
#14
James W T Toh, Nelson Wang, Christopher J Young, Matthew J F X Rickard, Anil Keshava, Peter Stewart, Viraj Kariyawasam, Rupert Leong
BACKGROUND: Most patients with Crohn's disease still require surgery despite significant advances in medical therapy, surveillance, and management strategies. OBJECTIVE: The purpose of this study was to assess surgical strategies and outcomes in Crohn's disease, including surgical recurrence and emergency surgery. DESIGN: This was a multicenter, retrospective review of a prospectively collected database. SETTINGS: A specialist-referred cohort of patients with Crohn's disease between 1970 and 2009 was studied...
January 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29214408/anticipated-hiv-stigma-and-delays-in-regular-hiv-testing-behaviors-among-sexually-active-young-gay-bisexual-and-other-men-who-have-sex-with-men-and-transgender-women
#15
Kristi E Gamarel, Kimberly M Nelson, Rob Stephenson, Olga J Santiago Rivera, Danielle Chiaramonte, Robin Lin Miller
Young gay, bisexual and other men who have sex with men (YGBMSM) and young transgender women are disproportionately affected by HIV/AIDS. The success of biomedical prevention strategies is predicated on regular HIV testing; however, there has been limited uptake of testing among YGBMSM and young transgender women. Anticipated HIV stigma-expecting rejection as a result of seroconversion- may serve as a significant barrier to testing. A cross-sectional sample of YGBMSM (n = 719, 95.5%) and young transgender women (n = 33, 4...
December 6, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/29214241/text-messaging-may-engage-and-benefit-adults-with-type-2-diabetes-regardless-of-health-literacy-status
#16
Erin M Bergner, Lyndsay A Nelson, Russell L Rothman, Lindsay Mayberry
Background: Technology-delivered interventions have the potential to improve diabetes self-care and glycemic control among adults with type 2 diabetes (T2D). However, patients who do not engage with interventions may not reap benefits, and there is little evidence on how engagement with mobile health interventions varies by health literacy status. Objective: This study explored how patients with limited health literacy engaged with and experienced Rapid Education/Encouragement and Communications for Health (REACH), a text messaging intervention designed to support the self-care adherence of disadvantaged patients with T2D...
October 2017: Health Literacy Research and Practice
https://www.readbyqxmd.com/read/29213079/human-cd26high-t-cells-elicit-tumor-immunity-against-multiple-malignancies-via-enhanced-migration-and-persistence
#17
Stefanie R Bailey, Michelle H Nelson, Kinga Majchrzak, Jacob S Bowers, Megan M Wyatt, Aubrey S Smith, Lillian R Neal, Keisuke Shirai, Carmine Carpenito, Carl H June, Michael J Zilliox, Chrystal M Paulos
CD8+ T lymphocytes mediate potent immune responses against tumor, but the role of human CD4+ T cell subsets in cancer immunotherapy remains ill-defined. Herein, we exhibit that CD26 identifies three T helper subsets with distinct immunological properties in both healthy individuals and cancer patients. Although CD26neg T cells possess a regulatory phenotype, CD26int T cells are mainly naive and CD26high T cells appear terminally differentiated and exhausted. Paradoxically, CD26high T cells persist in and regress multiple solid tumors following adoptive cell transfer...
December 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/29212850/endothelial-transcriptomics-reveals-activation-of-fibrosis-related-pathways-in-hypertension
#18
Jonathan William Nelson, Mohammed Zubaerul Ferdaus, James A McCormick, Jessica Minnier, Sanjiv Kaul, David H Ellison, Anthony Paul Barnes
Hypertension poses a significant challenge to vasculature homeostasis and stands as the most common cardiovascular disease in the world. Its effects are especially profound on endothelial cells that form the inner lining of the vasculature and are directly exposed to the effects of excess pressure. Here, we characterize the in vivo transcriptomic response of cardiac endothelial cells to hypertension by rapidly isolating these cells from the spontaneous hypertension mouse model BPH/2J and its normotensive BPN/3J control strain and performing and RNA sequencing on both...
December 6, 2017: Physiological Genomics
https://www.readbyqxmd.com/read/29212710/clinical-trial-design-the-nobility-of-randomization
#19
REVIEW
Nelson L Michael
A clinical trial evaluating HIV vaccine therapy teaches us much about optimal design (Sneller et al, this issue).
December 6, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/29212509/incremental-cost-and-cost-effectiveness-of-low-dose-high-frequency-training-in-basic-emergency-obstetric-and-newborn-care-as-compared-to-status-quo-part-of-a-cluster-randomized-training-intervention-evaluation-in-ghana
#20
Michelle Willcox, Heather Harrison, Amos Asiedu, Allyson Nelson, Patricia Gomez, Amnesty LeFevre
BACKGROUND: Low-dose, high-frequency (LDHF) training is a new approach best practices to improve clinical knowledge, build and retain competency, and transfer skills into practice after training. LDHF training in Ghana is an opportunity to build health workforce capacity in critical areas of maternal and newborn health and translate improved capacity into better health outcomes. METHODS: This study examined the costs of an LDHF training approach for basic emergency obstetric and newborn care and calculates the incremental cost-effectiveness of the LDHF training program for health outcomes of newborn survival, compared to the status quo alternative of no training...
December 6, 2017: Globalization and Health
keyword
keyword
6278
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"