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donor motivations

Yolentha Maria Slootweg, Johanna Maria Koelewijn, Wim L de Kort, Masja de Haas, Eva-Maria Merz
BACKGROUND: The successful introduction of prophylaxis with anti-RhD immunoglobulin has resulted in a significant decline of pregnancy-related RhD immunizations but also has decreased the availability of naturally immunized women as (new) anti-D donors. An influx of new donors is necessary to maintain a sufficient pool of anti-D donors. We investigated motivators, barriers, and predictors for anti-D donorship in RhD-immunized women. STUDY DESIGN AND METHODS: A mixed-methods design was applied, including focus group discussions and questionnaires...
March 12, 2018: Transfusion
Laura M Candelaria, Diane L Spatz, Noreen Giordano
OBJECTIVE: To examine the experiences of women who donated breast milk to a hospital-based milk bank regulated under the policies and procedures set forth by the Human Milk Banking Association of North America (HMBANA). DESIGN: Qualitative, phenomenological design. SETTING: The Mothers' Milk Bank in a children's hospital in the Northeastern region of the United States. PARTICIPANTS: Twelve HMBANA-approved milk donors older than 21 years with infants hospitalized in the NICU...
February 22, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
S Saha, B Chandra
OBJECTIVES: The present study aims to fill the gap in the literature by conducting a comprehensive research on Indian donor's intention towards voluntary blood donation in India. The study attempts to conceptualize and validate an integrative framework incorporating voluntary function inventory (VFI) in the theory of planned behaviour (TPB) model with the purpose tomeasure the voluntary blood donation intention. MATERIAL AND METHODS: Structural equation modeling (SEM) has been used to rigorously test the hypothesized interrelationships among the underlying motives influencing voluntary blood donation intention...
February 19, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
Eric W Jones, Jean M Carlson
In this paper we study antibiotic-induced C. difficile infection (CDI), caused by the toxin-producing C. difficile (CD), and implement clinically-inspired simulated treatments in a computational framework that synthesizes a generalized Lotka-Volterra (gLV) model with SIR modeling techniques. The gLV model uses parameters derived from an experimental mouse model, in which the mice are administered antibiotics and subsequently dosed with CD. We numerically identify which of the experimentally measured initial conditions are vulnerable to CD colonization, then formalize the notion of CD susceptibility analytically...
February 16, 2018: PLoS Computational Biology
Angelique F Ralph, Phyllis Butow, Jonathan C Craig, Jeremy R Chapman, John S Gill, John Kanellis, Allison Tong
AIM: Careful assessment of the potential donor-recipient relationship is recommended by guidelines to prevent undue coercion, and ensure realistic expectations and genuine motivations. However, relationships are complex, nuanced and value-laden, and can be challenging to evaluate in living kidney donation. We aimed to describe the attitudes and approaches of transplant clinicians towards assessing the relationship between potential living kidney donors and their recipients. METHODS: Semi-structured interviews were conducted with 54 transplant clinicians (nephrologists, surgeons, coordinators, social workers, psychiatrists and psychologists) from 32 transplant centres across nine countries including Australia, United States, Canada and New Zealand...
February 13, 2018: Nephrology
E Ferguson, C Lawrence
BACKGROUND AND OBJECTIVES: The design of effective donor recruitment campaigns requires an accurate understanding of donor motivations. This requires cross-validation of theoretically derived, psychometrically assessed motivations with behavioural preferences. Theoretical models suggest that blood donors should be more sensitive than nondonors to violations of fairness norms. Specifically, active blood donors, compared to nondonors, should endorse beliefs of reciprocal fairness, norms of both positive and negative reciprocity and reject more unfair offers in a behavioural economic game (the ultimatum game)...
February 9, 2018: Vox Sanguinis
Saba Tariq, Sundus Tariq, Shireen Jawed, Saffee Tariq
OBJECTIVE: To assess the knowledge, practices and attitude of medical students towards blood donation. METHODS: This cross-sectional study was conducted at the University of Faisalabad, Faisalabad, Pakistan, from April to August 2016, and comprised female medical students. Multi-stage sampling technique was employed. A structured questionnaire was included as data-collection tool. Statistical analysis was done using SPSS 20. RESULTS: Of the 500 students, 469(93...
January 2018: JPMA. the Journal of the Pakistan Medical Association
A M Warren, G Testa, T Anthony, G J McKenna, G B Klintmalm, K Wallis, E C Koon, R T Gunby, L Johannesson
Emerging research suggests that uterus transplantation is a viable option for women without a uterus who want to become pregnant and carry a child to term. Currently, no knowledge exists regarding nondirected uterus donors. This study (NCT 02656550) explored the baseline psychological characteristics of nondirected uterus donors at a single study site. Of the 62 potential donors who underwent initial screening, six nondirected donors were chosen and participated in uterus donation. Participants received a comprehensive evaluation, which included clinical history and psychological assessments...
January 24, 2018: American Journal of Transplantation
Paul A Wieringa, Ana Rita Gonçalves de Pinho, Silvestro Micera, Richard J A van Wezel, Lorenzo Moroni
Biofabrication techniques have endeavored to improve the regeneration of the peripheral nervous system (PNS), but nothing has surpassed the performance of current clinical practices. However, these current approaches have intrinsic limitations that compromise patient care. The "gold standard" autograft provides the best outcomes but requires suitable donor material, while implantable hollow nerve guide conduits (NGCs) can only repair small nerve defects. This review places emphasis on approaches that create structural cues within a hollow NGC lumen in order to match or exceed the regenerative performance of the autograft...
January 19, 2018: Advanced Healthcare Materials
Trudie Gerrits
In this article, I address reproductive travel to Ghana, based on research conducted in two private fertility clinics. Both clinics attract clients from West African countries as well as Ghanaian people living in US and Europe. Their motivations to visit these clinics include positive "testimonies" about treatment results, "bioavailability" of matching donor material and surrogates, lower treatment costs and the circumvention of restricting regulations in the country of residence. Next to structural features in the countries of residence and in Ghana, I discuss the centrality of communication technologies facilitating reproductive travel and argue that the "international choreographies" of reproductive travel are co-shaped by the unique biographies and transnational relationships of the people involved...
January 15, 2018: Medical Anthropology
Anne Hambro Alnæs
Norway provides total social welfare coverage for organ transplantations, including free immunosuppressive medication and prepaid life-long follow up for both recipients and donors. Despite these benefits the proportion of living kidney donors (LKD) has in recent years declined from around 40% (2011) of all kidney transplantations to 24% (2016). This study suggests harnessing patient- and donor-narratives as a tool for addressing the current fall in donation rates. The hospital records of 18 recipient/donor dyads were compared with patient and donor accounts elicited in semi-structured interviews...
January 13, 2018: Medicine, Health Care, and Philosophy
Anke Dunkel, Kent Nakamoto, Peter J Schulz
OBJECTIVE: Organ transplantation is plagued by limited availability of organs. This study investigated the effect of messages promoting organ donation which were customized according to the language-defined micro-cultures in Switzerland. METHODS: Community-, informative-, and emotional-oriented messages were carried by conventional flyers. A 3 × 3 between-subjects experiment was conducted with short- and long-term willingness to donate, long-term signing of organ donation card and long-term interpersonal communication on organ donation as outcome variables...
December 29, 2017: Patient Education and Counseling
Elisabeth Paul, Mohamed Lamine Dramé, Jean-Pierre Kashala, Armand Ekambi Ndema, Marcel Kounnou, Julien Codjovi Aïssan, Karel Gyselinck
BACKGROUND: Performance-based financing (PBF) is often proposed as a way to improve health system performance. In Benin, PBF was launched in 2012 through a World Bank-supported project. The Belgian Development Agency (BTC) followed suit through a health system strengthening (HSS) project. This paper analyses and draws lessons from the experience of BTC-supported PBF alternative approach - especially with regards to institutional aspects, the role of demand-side actors, ownership, and cost-effectiveness - and explores the mechanisms at stake so as to better understand how the "PBF package" functions and produces effects...
April 15, 2017: International Journal of Health Policy and Management
E A Akam, R D Utterback, J R Marcero, H A Dailey, E Tomat
The iron metabolism of malignant cells, which is altered to ensure higher acquisition and utilization, motivates the investigation of iron chelation strategies in cancer treatment. In a prochelation approach aimed at increasing intracellular specificity, disulfide reduction/activation switches are incorporated on iron-binding scaffolds resulting in intracellularly activated scavengers. Herein, this strategy is applied to several tridentate donor sets including thiosemicarbazones, aroylhydrazones and semicarbazones...
January 4, 2018: Journal of Inorganic Biochemistry
Hannelore Hendrickx, Phillip N Blondeel, Hanna Van Parys, Nathalie A Roche, Patrick C Peeters, Hubert F Vermeersch, Xavier Rogiers, Kristiane Van Lierde, Gilbert M D Lemmens
Increasing evidence points to good functional, aesthetic, and psychosocial outcomes after face transplantation. However, research investigating how patients and their families subjectively experience the transplantation process is lacking thus far. This study aims to investigate the personal experiences of a blind face transplant patient and his partner. In-depth interviews exploring different experiences were conducted with both partners separately 20 months after face transplantation. The interviews were analyzed using interpretative phenomenological analysis...
January 4, 2018: Journal of Craniofacial Surgery
Annika M Kisch, Anna Forsberg, Isabell Fridh, Matilda Almgren, Martina Lundmark, Charlotte Lovén, Anne Flodén, Madeleine Nilsson, Veronika Karlsson, Annette Lennerling
BACKGROUND: Studies on living donors from the donors' perspective show that the donation process involves both positive and negative feelings involving vulnerability. Qualitative studies of living kidney, liver, and allogeneic hematopoietic stem cell donors have not previously been merged in the same analysis. Therefore, our aim was to synthesize current knowledge of these donors' experiences in order to deepen understanding of the meaning of being a living donor for the purpose of saving or extending someone's life...
January 2, 2018: Transplantation
Bengt von Zur-Mühlen, Shinji Yamamoto, Jonas Wadström
BACKGROUND We sought to study gender differences and differences over time with respect to demographics, relation to recipient, donor motives, and experiences of live kidney donation. MATERIAL AND METHODS In all, 455 consecutive live kidney donors, representing all of the donors at our center between 1974 and 2008 were considered for this study. There were 28 deceased donors and 14 donors who had moved abroad, leaving 413 donors; 387 (94%) agreed to participate in this study. A questionnaire was sent and the answers was analyzed for gender differences and, where relevant, for changes over time...
December 29, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
N Techataweewan, C Panthongviriyakul, Y Toomsan, W Mothong, P Kanla, A Chaichun, P Amarttayakong, N Tayles
BACKGROUND: Culture, society and spirituality all contribute to variability in the characteristics of human body donors and donation programmes worldwide. The donors and the body donation programme at Khon Kaen University, northeast Thailand, reflect all these aspects of Thailand, including the status accorded to the donors and the ceremonial acknowledgment of the donors and their families. METHODS: Data from the programme records and from surveys of samples of currently registering donors and recently received donor bodies are analysed to define the characteristics of both registering and received donors, including motivation, demography, socio-economic status, health, and use of the bodies...
December 20, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
Pietro Bortoletto, Leslie V Farland, Elizabeth S Ginsburg, Randi H Goldman
OBJECTIVE: To determine whether the general public supports intergenerational oocyte donation. DESIGN: Cross-sectional study. SETTING: Not applicable. PATIENT(S): A nationally representative sample based on age distribution of United States residents. INTERVENTIONS(S): Not applicable. MAIN OUTCOME MEASURE(S): Characteristics of respondents who supported (strongly agree and agree) various oocyte donation practices were compared with participants who did not support them (disagree and strongly disagree) using log binomial regression to calculate risk ratios (RRs) and 95% confidence intervals of support (95% CIs)...
December 12, 2017: Fertility and Sterility
Lindsey M Dorflinger, Sanjay Kulkarni, Carrie Thiessen, Sharon Klarman, Liana Fraenkel
The need for kidneys for transplantation continues to far surpass the number of donors. Although studies have shown that most people are aware of and support the idea of living donation, it remains unclear what motivates individuals who are aware, knowledgeable, and in support of donation to actually donate, or conversely, what deters them from donating. Utilizing nominal group technique, 30 individuals participated in 4 groups in which they brainstormed factors that would impact willingness to be a living donor and voted on which factors they deemed most important...
January 1, 2017: Progress in Transplantation
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