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https://www.readbyqxmd.com/read/27887716/who-requests-their-sperm-donor-s-identity-the-first-ten-years-of-information-releases-to-adults-with-open-identity-donors
#1
Joanna E Scheib, Alice Ruby, Jean Benward
OBJECTIVE: To report findings from 10 years of requests from adults eligible to obtain their open-identity sperm donor's information. DESIGN: Analysis of archived family and donor data. Semistructured interviews at information releases. SETTING: Not applicable. PATIENT(S): A total of 85 DI adults requesting 43 donor identities; program data on 256 DI families. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): We identified [1] demographic predictors of requesting donor identities, [2] information release timing and length, and [3] request motives...
November 22, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27881620/catching-fakes-new-markers-of-urine-sample-validity-and-invalidity
#2
Melissa M Goggin, Cheng-Min Tann, Anna Miller, An Nguyen, Gregory C Janis
Urine drug testing is common for workplace drug testing, prescription management, emergency medicine and the criminal justice system. Unsurprisingly, with the significant consequences based upon the results of urine drug testing, a donor in need of concealing the contents of their sample is highly motivated to cheat the process. Procedures and safeguards ensuring sample validity are well known, and include measuring sample temperature at the time of collection, and laboratory measurements of creatinine, specific gravity and pH...
November 22, 2016: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/27879190/transplantation-in-africa-an-overview
#3
Elmi Muller
Africa is underdeveloped in terms of treatment options for patients with end-stage renal failure. Economic growth and corresponding increases in health expenditures in the African region mean that we can confidently anticipate increased demand for organ transplantation within the region over the next few years. Renal failure in Africa occurs mainly due to glomerular nephropathies, hypertension, diabetes, and HIV. For the subset of the population that might be considered medically suitable for transplantation, demand for transplantation is tightly constrained by the availability of specialist physicians and surgeons, pathology facilities, capacity to achieve acceptable graft outcomes, cultural and religious attitudes towards organ donation, trust in the health system, and the extent to which patients are able to meet the costs of surgery and ongoing immunosuppression...
2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27875643/crowdfunding-for-medical-care-ethical-issues-in-an-emerging-health-care-funding-practice
#4
Jeremy Snyder
Crowdfunding websites allow users to post a public appeal for funding for a range of activities, including adoption, travel, research, participation in sports, and many others. One common form of crowdfunding is for expenses related to medical care. Medical crowdfunding appeals serve as a means of addressing gaps in medical and employment insurance, both in countries without universal health insurance, like the United States, and countries with universal coverage limited to essential medical needs, like Canada...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27865131/evaluation-of-cellular-uptake-cytotoxicity-and-cellular-ultrastructural-effects-of-heteroleptic-oxidovanadium-iv-complexes-of-salicylaldimines-and-polypyridyl-ligands
#5
Gonzalo Scalese, Isabel Correia, Julio Benítez, Santiago Rostán, Fernanda Marques, Filipa Mendes, António Pedro Matos, João Costa Pessoa, Dinorah Gambino
Searching for prospective vanadium-based drugs for cancer treatment, a new series of structurally related [V(IV)O(L-2H)(NN)] compounds (1-8) was developed. They include a double deprotonated salicylaldimine Schiff base ligand (L-2H) and different NN-polypyridyl co-ligands having DNA intercalating capacity. Compounds were characterized in solid state and in solution. EPR spectroscopy suggests that the NN ligands act as bidentate and bind through both nitrogen donor atoms in an axial-equatorial mode. The cytotoxicity was evaluated in human tumoral cells (ovarian A2780, breast MCF7, prostate PC3)...
November 9, 2016: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/27865040/psychological-outcomes-of-living-liver-donors-from-a-multi-center-prospective-study-results-from-the-adult-to-adult-living-donor-liver-transplantation-cohort-study-a2all
#6
Z Butt, M A Dew, Q Liu, M A Simpson, A R Smith, J Zee, B W Gillespie, S E Abbey, D P Ladner, R Weinrieb, R A Fisher, S Hafliger, N Terrault, J Burton, A H Sherker, A Di Martini
While single-center and cross-sectional studies have suggested modest impact of liver donation on donor psychological well-being, few studies have assessed these outcomes prospectively among a large cohort. We conducted one of the largest, prospective, multi-center studies of psychological outcomes in living liver donors within the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL-2) Consortium. 271 (91%) of 297 eligible donors were interviewed at least once at pre-donation, 3-, 6-, 12- and 24-months post-donation using validated measures...
November 19, 2016: American Journal of Transplantation
https://www.readbyqxmd.com/read/27853152/a-natural-light-driven-inward-proton-pump
#7
Keiichi Inoue, Shota Ito, Yoshitaka Kato, Yurika Nomura, Mikihiro Shibata, Takayuki Uchihashi, Satoshi P Tsunoda, Hideki Kandori
Light-driven outward H(+) pumps are widely distributed in nature, converting sunlight energy into proton motive force. Here we report the characterization of an oppositely directed H(+) pump with a similar architecture to outward pumps. A deep-ocean marine bacterium, Parvularcula oceani, contains three rhodopsins, one of which functions as a light-driven inward H(+) pump when expressed in Escherichia coli and mouse neural cells. Detailed mechanistic analyses of the purified proteins reveal that small differences in the interactions established at the active centre determine the direction of primary H(+) transfer...
November 17, 2016: Nature Communications
https://www.readbyqxmd.com/read/27816867/effectiveness-of-weight-loss-intervention-in-highly-motivated-people
#8
Mariétou H Ouayogodé
A variety of approaches have been implemented to address the rising obesity epidemic, with limited success. I consider the success of weight loss efforts among a group of highly motivated people: those required to lose weight in order to qualify for a life-saving kidney transplantation. Out of 246 transplantation centers, I identified 156 (63%) with explicit body mass index (BMI) requirements for transplantation, ranging from 30 to 50kg/m(2). Using the United States national registry of transplant candidates, I examine outcomes for 29,608 obese deceased-donor transplant recipients between 1990 and 2010...
October 17, 2016: Economics and Human Biology
https://www.readbyqxmd.com/read/27795455/blood-soy-milk-and-vitality-the-wartime-origins-of-blood-banking-in-china-1943-45
#9
Wayne Soon
This article examines the multiple meanings of blood transfusion and banking in modern China through the history of the first Chinese blood bank, established by the Overseas Chinese in 1943 to solicit blood for the war effort. Through investigating the attitudes of Chinese soldiers and civilians toward the blood bank, this article argues for the multiplicity of motivations underpinning society's attitudes toward blood banking and donation. Cultural notions of blood were an important but not the sole factor in their consideration...
2016: Bulletin of the History of Medicine
https://www.readbyqxmd.com/read/27788789/a-study-on-the-attitude-toward-kidney-transplantation-and-factors-among-hemodialysis-patients-in-china
#10
B Qiao, L Liu, J Liu, J Xie
BACKGROUND: Kidney transplantation (KT) is the most effective treatment for patients with end-stage renal disease. However, objective data regarding the willingness of patients with end-stage renal disease to undergo transplantation are lacking in China. The purpose of this study was to examine the attitudes and impact factors regarding KT among patients with end-stage renal disease undergoing hemodialysis. METHODS: This study used a cross-sectional approach. Between June and July 2015, a total of 326 hemodialysis outpatients completed a self-designed questionnaire to assess their attitudes toward KT and satisfaction with dialysis...
October 2016: Transplantation Proceedings
https://www.readbyqxmd.com/read/27759390/mimicking-photosynthesis-with-electrode-supported-lipid-nanoassemblies
#11
Mingming Wang, Wei Zhan
The grand scale, ultimate efficiency, and sustainability of natural photosynthesis have inspired generations of researchers in biomimetic light energy utilization. As an essential and ubiquitous component in all photosynthetic machinery, lipids and their assemblies have long been recognized as powerful molecular scaffolds in building artificial photosynthetic systems. Model lipid bilayers, such as black lipid membranes and liposomes (vesicles), have been extensively used to host natural as well as synthetic photo- and redox-active species, thereby enabling key photosynthetic processes, such as energy transfer and photoinduced electron transfer, to be examined in well-defined, natural-like membrane settings...
October 19, 2016: Accounts of Chemical Research
https://www.readbyqxmd.com/read/27717388/performance-based-incentives-may-be-appropriate-to-address-challenges-to-delivery-of-prevention-of-vertical-transmission-of-hiv-services-in-rural-mozambique-a-qualitative-investigation
#12
Roseanne C Schuster, Octávio de Sousa, Jacqueline Rivera, Rebecca Olson, Delphine Pinault, Sera L Young
BACKGROUND: Performance-based incentives (PBIs) have garnered global attention as a promising strategy to improve healthcare delivery to vulnerable populations. However, literature gaps in the context in which an intervention is implemented and how the PBIs were developed exist. Therefore, we (1) characterized the barriers and promoters to prevention of vertical transmission of HIV (PVT) service delivery in rural Mozambique, where the vertical transmission rate is 12 %, and (2) assessed the appropriateness for a PBI's intervention and application to PVT...
October 7, 2016: Human Resources for Health
https://www.readbyqxmd.com/read/27712678/donations-and-dependence-individual-contributor-strategies-in-house-elections
#13
Jennifer A Heerwig
Despite the importance of individual contributors to financing federal candidates, past work has largely neglected this crucial financial constituency in favor of research on corporate and trade political action committees (PACs). By contrast, in this study I offer the first analysis of aggregate contributions from the population of individual contributors to House candidates. Using an original big dataset constructed from over fifteen million Federal Election Commission (FEC) disclosure records, I identify individual contributors (rather than contributions) and trace the variation in their strategies across types of House candidates...
November 2016: Social Science Research
https://www.readbyqxmd.com/read/27698073/disclosure-of-donor-conception-in-the-era-of-non-anonymity-safeguarding-and-promoting-the-interests-of-donor-conceived-individuals
#14
REVIEW
Sophie Zadeh
This article responds to a debate article published in Human Reproduction earlier this year. In that article, the authors suggested that parents should be encouraged to disclose the use of donor gametes to their children given rapid and widespread advances in genetic testing and sequencing. However, there is an urgent need to engage with the assertion that in this context, telling children about their donor conception both safeguards and promotes their interests, particularly if such disclosure is motivated by parents' anxieties about accidental discovery...
November 2016: Human Reproduction
https://www.readbyqxmd.com/read/27692950/changes-in-united-states-heart-allocation-a-community-energized-to-improve-policy
#15
Joseph G Rogers
Donor heart allocation in the United States has not evolved in concert with changes in the characteristics of patients on the waiting list or evolution in technology. Data showing the growing population of patients with advanced heart failure coupled with the relatively fixed number of cardiac donors and regional access disparities motivated the United Network for Organ Sharing (UNOS) Thoracic Committee to reexamine candidate prioritization and broader organ sharing. The resultant proposed policy change stratifies patients in a more granular manner based primarily on wait-list mortality and is designed to expand the geographic boundaries to permit greater access to donor hearts for the most critically ill patients awaiting transplant...
August 31, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27662074/neoliberal-optimism-applying-market-techniques-to-global-health
#16
Yuyang Mei
Global health and neoliberalism are becoming increasingly intertwined as organizations utilize markets and profit motives to solve the traditional problems of poverty and population health. I use field work conducted over 14 months in a global health technology company to explore how the promise of neoliberalism re-envisions humanitarian efforts. In this company's vaccine refrigerator project, staff members expect their investors and their market to allow them to achieve scale and develop accountability to their users in developing countries...
September 23, 2016: Medical Anthropology
https://www.readbyqxmd.com/read/27633751/interviews-with-patients-who-traveled-from-macedonia-kosovo-the-netherlands-and-sweden-for-paid-kidney-transplantations
#17
L J van Balen, Frederike Ambagtsheer, N Ivanovski, W Weimar
BACKGROUND: Patients travel worldwide for paid kidney transplants. Although transplantations abroad are not always illegal, they are commonly perceived to be illegal and unethical involving risks. AIM: We aimed to describe the motivations and experiences of patients who traveled abroad for paid kidney transplantations and to examine how these transplantations were facilitated. METHODS: We interviewed 22 patients who traveled from Macedonia/Kosovo, the Netherlands, and Sweden for paid kidney transplantations between years 2000 and 2009...
September 15, 2016: Progress in Transplantation
https://www.readbyqxmd.com/read/27605848/blood-donor-selection-and-deferral-pattern-as-an-important-tool-for-blood-safety-in-a-tertiary-care-hospital
#18
Manisha Shrivastava, Nehal Shah, Seema Navaid, Kalpana Agarwal, Gourav Sharma
CONTEXT: Blood donor selection criteria based on science and regulatory rules influence donor as well recipient safety and demographics. AIM: To evaluate and analyze the blood donor deferral pattern and its causes among blood donors in a tertiary care hospital blood bank and to review its influence on blood safety. SETTINGS AND DESIGN: Hospital based blood bank, retrospective analysis. SUBJECTS AND METHODS: The data available as donor deferral record over a period of 13 years from 2001 to 2013 was analyzed...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27605846/attitude-toward-blood-donation-among-medical-and-nonmedical-students-across-karachi
#19
Muhammad Osama Anwer, Shaikh Hamiz Ul Fawwad, Sanam Anwer, Arif Ali
AIM: To evaluate the factors that motivate and discourage medical and nonmedical students from donating blood voluntarily and to assess the level of awareness and knowledge regarding blood donation. MATERIALS AND METHODS: We conducted a cross-sectional descriptive study from August 2011 to May 2012 across different universities of Karachi covering both private and public sector. Predesigned questionnaires were filled by students. A total of 690 students participated in the study, 345 from each...
July 2016: Asian Journal of Transfusion Science
https://www.readbyqxmd.com/read/27604901/schools-of-public-health-in-low-and-middle-income-countries-an-imperative-investment-for-improving-the-health-of-populations
#20
Fauziah Rabbani, Leah Shipton, Franklin White, Iman Nuwayhid, Leslie London, Abdul Ghaffar, Bui Thi Thu Ha, Göran Tomson, Rajiv Rimal, Anwar Islam, Amirhossein Takian, Samuel Wong, Shehla Zaidi, Kausar Khan, Rozina Karmaliani, Imran Naeem Abbasi, Farhat Abbas
BACKGROUND: Public health has multicultural origins. By the close of the nineteenth century, Schools of Public Health (SPHs) began to emerge in western countries in response to major contemporary public health challenges. The Flexner Report (1910) emphasized the centrality of preventive medicine, sanitation, and public health measures in health professional education. The Alma Ata Declaration on Primary Health Care (PHC) in 1978 was a critical milestone, especially for low and middle-income countries (LMICs), conceptualizing a close working relationship between PHC and public health measures...
2016: BMC Public Health
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