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Pipelle biopsy endometrial

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https://www.readbyqxmd.com/read/28511086/local-endometrial-injury-in-women-with-failed-ivf-undergoing-a-repeat-cycle-a-randomized-controlled-trial
#1
Aleyamma Tk, Himanshu Singhal, Prasanna S Premkumar, Mousumi Acharya, Mohan S Kamath, Korula George
OBJECTIVE: To evaluate the effectiveness of local endometrial injury in women undergoing in vitro fertilization (IVF) with at least one previous unsuccessful attempt. STUDY DESIGN: Randomized controlled trial. Recruited women were randomized into two groups. In group A (pipelle group), women underwent pipelle biopsy twice in the luteal phase in the cycle prior to IVF. In group B (control), women did not undergo any intervention prior to IVF. The primary outcome was clinical pregnancy rate...
May 4, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28420909/lidocaine-and-tenoxicam-effectiveness-for-pain-relief-during-pipelle-non-randomised-double-blind-placebo-controlled-trial
#2
Mehmet Akif Sargin, Murat Yassa, Ayhan Celik, Emrah Ergun, Niyazi Tug
OBJECTIVE: To compare the effectiveness of intrauterine lidocaine infusion with lidocaine and intravenous tenoxicam for decreasing the pain levels associated with endometrial biopsy. METHODS: This double-blind, placebo-controlled trial was conducted at Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey, from May to November 2015, and comprised patients undergoing endometrial biopsy with Pipelle. Intrauterine lidocaine infusion, paracervical block with lidocaine, intravenous tenoxicam or 4ml intravenous normal saline administered prior to biopsy...
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28389441/diagnostic-accuracy-of-endometrial-biopsy-in-relation-to-the-amount-of-tissue
#3
Casper Reijnen, Nicole Cm Visser, Johan Bulten, Leon Fag Massuger, Louis Jm van der Putten, Johanna Ma Pijnenborg
AIMS: For the diagnostic workup of postmenopausal bleeding, histological examination of the endometrium is frequently performed. Failure of endometrial sampling due to insufficient material is often reported but objective criteria for quality assessment of endometrial biopsies are lacking. The aim of the present study is to evaluate the association between the amount of tissue obtained by endometrial sampling and the diagnostic accuracy, and to establish a cut-off level for a minimal amount of tissue required for a conclusive diagnosis...
April 7, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28315625/endometrial-injury-for-women-with-previous-in-vitro-fertilization-failure-does-it-improve-pregnancy-rate
#4
Aleksandra Zygula, Iwona Szymusik, Barbara Grzechocinska, Piotr Marianowski, Miroslaw Wielgos
Implantation failure is one of the major factors limiting success of in vitro fertilization (IVF) treatment. According to ESHRE 2009 data only 32% of fresh embryo transfers resulted in clinical pregnancies. There are many ideas to improve the treatment outcomes, endometrial injury being one of them. It has been suggested that local endometrial injury, performed either by pipelle biopsy or hysteroscopy, may increase clinical pregnancy rate. However, up to date literature is widely disparate on that subject. There is no conclusion with regard to optimal timing, the number and technique of the procedure...
November 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28274004/triple-synchronous-malignancies-in-genital-tract-primary-endometrial-ovarian-and-fallopian-tube-carcinoma-a-case-report
#5
Ozgur Kan, Aysegul Alkilic, Batuhan Turgay, Ali Gemici, Cem Somer Atabekoglu
Synchronous malignancies, including three or more tumours, are extremely rare. Herein, we present a case of a woman with a concurrent simultaneous endometrial, ovarian and fallopian tubal carcinoma with different histopathological characteristics. A 55-year-old postmenopausal woman with a diagnosis of endometrial adenocarcinoma by pipelle biopsy, underwent surgical staging. Final pathology result was reported as synchronous stage IA grade 2 endometrioid adenocarcinoma of the uterus, stage IA grade 2 mucinous adenocarcinoma of the right ovary and in situ serous cystadenocarcinoma of the right fallopian tube...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28173742/ultrastructural-evaluation-of-eutopic-endometrium-of-infertile-women-with-and-without-endometriosis-during-the-window-of-implantation
#6
Michele G Da Broi, Carlos V Rocha, Filomena M Carvalho, Wellington P Martins, Rui A Ferriani, Paula A Navarro
Endometriosis is frequently associated with infertility and it is believed that the impairment of endometrial receptivity may be one of the mechanisms involved in this condition. Pinopodes are endometrial cycle-dependent structures that seem to participate in embryo implantation, and alterations in their presence and/or morphology during the window of implantation could affect the endometrial receptivity and be involved in the disease-related infertility. However, the data on pinopodes in these women are scarce and inconclusive...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28149144/effect-of-cervical-lidocaine-gel-for-pain-relief-in-pipelle-endometrial-sampling
#7
Ibrahim Karaca, Omer Erkan Yapca, Mehmet Adiyeke, Emrah Toz, Suna Yildirim Karaca
OBJECTIVE: To evaluate the efficacy of cervical lidocaine gel in reducing patient discomfort during Pipelle endometrial sampling. MATERIALS AND METHODS: From September 2012 to January 2013, 137 patients were evaluated with Pipelle endometrial biopsy. For group 1 (77 women), 2% lidocaine gel was applied to the cervical canal 3 min before endometrial sampling. For group 2 (60 women), a placebo gel was applied. The pain experienced by the patients during biopsy was evaluated using a 100 mm visual analog scale...
October 2016: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/27912906/patient-and-provider-factors-associated-with-endometrial-pipelle-sampling-failure
#8
Shalkar Adambekov, Sharon L Goughnour, Suketu Mansuria, Nicole Donnellan, Esther Elishaev, Hugo J Villanueva, Robert P Edwards, Dana H Bovbjerg, Faina Linkov
OBJECTIVE: To explore risk factors associated with sampling failure in women who underwent Pipelle biopsy. METHODS: A consecutive sample of 201 patient records was selected from women who underwent Pipelle biopsy procedures for suspected uterine pathology in a large healthcare system over a 6-month period (January 2013 through June 2013). Personal and medical data including age, BMI, gravidity and parity, and previous history of Pipelle biopsy were abstracted from medical records for each patient...
February 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/27909879/investigating-vaginal-bleeding-in-postmenopausal-women-found-to-have-an-endometrial-thickness-of-equal-to-or-greater-than-10%C3%A2-mm-on-ultrasonography
#9
Hilary L Turnbull, Nikolaos Akrivos, Paul Simpson, Timothy J Duncan, Joaquin J Nieto, Nikolaos Burbos
PURPOSE: This aim of this study is to determine the risk of endometrial cancer in symptomatic postmenopausal women, when endometrial thickness on transvaginal ultrasonography is equal to or greater than 10 mm, and subsequent office-based endometrial sampling histology is negative. METHODS: This is a prospective cross-sectional study, performed in a gynaecological oncology centre in the United Kingdom between February 2008 and July 2012. All postmenopausal women presenting with vaginal bleeding were investigated using transvaginal ultrasonography...
February 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27747726/post-menopausal-vaginal-hemorrhage-related-to-the-use-of-a-hop-containing-phytotherapeutic-product
#10
Florence van Hunsel, Sonja van de Koppel, Eugène van Puijenbroek
Two 54-year-old women developed abdominal cramps and vaginal hemorrhage as a result of endometrial hyperplasia during treatment with a hop-containing phytotherapeutic product (MenoCool(®)) for post-menopausal complaints. The women used the hop-containing phytotherapeutic product (418 mg of hop per tablet) twice daily (1 and 0.5 tablets by both patient A and B). Patient A developed abdominal cramps and vaginal hemorrhage after 2 months of use. After gynecological examination, she was diagnosed with endometrial hyperplasia...
December 2015: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27678583/endometrial-pipelle-biopsy-identifying-a-polyp-versus-office-hysteroscopy
#11
J K To, M Levie, S Chudnoff
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27629129/assessment-of-the-usefulness-of-pipelle-biopsy-in-gynecological-diagnostics
#12
Szymon Piątek, Grzegorz Panek, Mirosław Wielgoś
OBJECTIVES: The aim of this study is to assess the effectiveness of pipelle in sampling diagnostic material from the uterine cavity and determining clinical factors, which may affect its effectiveness. MATERIAL AND METHODS: The retrospective analysis included 312 patients who underwent pipelle biopsy because of various indications. Evaluated factors which may affect the effectiveness of this method were: types of indications for the procedure, age, BMI, anteflexion or retroflexion of the uterus, presence of uterine fibroids, miscarriages, natural deliveries, deliveries in general...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27609758/identification-of-genes-differentially-expressed-in-menstrual-breakdown-and-repair
#13
Premila Paiva, Michelle G Lockhart, Jane E Girling, Moshe Olshansky, Nicole Woodrow, Jennifer L Marino, Martha Hickey, Peter A W Rogers
STUDY QUESTION: Does the changing molecular profile of the endometrium during menstruation correlate with the histological profile of menstruation. SUMMARY ANSWER: We identified several genes not previously associated with menstruation; on Day 2 of menstruation (early-menstruation), processes related to inflammation are predominantly up-regulated and on Day 4 (late-menstruation), the endometrium is predominantly repairing and regenerating. WHAT IS KNOWN ALREADY: Menstruation is induced by progesterone withdrawal at the end of the menstrual cycle and involves endometrial tissue breakdown, regeneration and repair...
December 2016: Molecular Human Reproduction
https://www.readbyqxmd.com/read/27525329/the-effect-of-endometrial-injury-on-pregnancy-rate-in-frozen-thawed-embryo-transfer-a-randomized-control-trial
#14
Abbas Aflatoonian, Ramesh Baradaran Bagheri, Robabe Hosseinisadat
BACKGROUND: Implantation failure is one of the most important factors limiting success in IVF treatment. The majority of trials have demonstrated favorable effect of endometrial injury on implantation success rate especially in women with recurrent implantation failure, while some studies failed to detect any benefit. OBJECTIVE: The purpose of our trial was to explore whether endometrial injury in luteal phase prior to frozen-thawed embryo transfer cycles would improve pregnancy outcomes? MATERIALS AND METHODS: We conducted a prospective controlled trial of 93 consecutive subjects at a research and clinical center for infertility...
July 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/27349264/management-of-postmenopausal-bleeding-by-general-practitioners-in-a-community-setting-an-observational-study
#15
Monique Stravens, Fali Langdana, John Short, Karyn Johnson, Bryony Simcock, Brett Shand, Graham McGeoch, Peter Sykes
AIM: To evaluate the safety and effectiveness of a clinical pathway for investigation of postmenopausal bleeding (PMB), managed primarily by general practitioners. Women with an endometrial thickness (ET) ≥5mm on transvaginal ultrasound (TVUS) require either a pipelle biopsy in primary care or referral for specialist care. METHOD: Data on 241 women with PMB were reviewed retrospectively over a 5-year follow-up period. Twenty-five women were excluded as they did not satisfy PMB clinical pathway criteria...
May 6, 2016: New Zealand Medical Journal
https://www.readbyqxmd.com/read/27296541/endometrial-injury-for-pregnancy-following-sexual-intercourse-or-intrauterine-insemination
#16
REVIEW
Sarah F Lensen, Marlies Manders, Carolina O Nastri, Ahmed Gibreel, Wellington P Martins, Gabriella E Templer, Cindy Farquhar
BACKGROUND: Intentional endometrial injury is currently being proposed as a technique to improve the probability of pregnancy in women undergoing assisted reproductive technologies (ART) such as in vitro fertilisation (IVF). Endometrial injury is often performed by pipelle biopsy or a similar technique, and is a common, simple, gynaecological procedure that has an established safety profile. However, it is also known to be associated with a moderate degree of discomfort/pain and requires an additional pelvic examination...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27219202/positive-predictive-value-of-endometrial-polyps-in-pipelle-aspiration-sampling-a-histopathological-study-of-195-cases
#17
Mimi T Y Seto, Philip P C Ip, Siew-Fei Ngu, Annie N Y Cheung, Ting-Chung Pun
OBJECTIVE: To estimate the positive predictive value of Pipelle endometrial sampling in detecting the presence of an underlying endometrial polyp. The secondary objective is to examine the histologic features that can predict the presence of endometrial polyps. STUDY DESIGN: This is a retrospective case review study. 195 women who had undergone diagnostic hysteroscopy and/or polypectomy were identified in a University teaching hospital. All patients had a prior polyp diagnosis in the Pipelle endometrial sample...
August 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27173475/diagnostic-impacts-of-serum-ca-125-levels-pap-smear-evaluation-and-endometrial-sampling-in-women-with-endometrial-clear-cell-carcinoma
#18
Nilufer Cetinkaya, İlker Selcuk, Bulent Ozdal, Mehmet M Meydanli, Tayfun Gungor
BACKGROUND: Endometrial clear cell carcinoma (ECCC) is a rare variant of endometrial cancer with an unfavorable prognosis. The aim of this study was to determine the relationships, if any, between preoperative serum cancer antigen 125 (CA-125) levels, the last Papanicolaou (Pap) smear, the results of endometrial biopsy and tumor histology, and disease-stage according to permanent histopathology. MATERIALS AND METHODS: The data of 26 women with ECCC were collected from their medical records to compare demographics, preoperative serum CA-125 levels, Pap test results, histological diagnosis of the endometrial biopsy, and tumor histology, as well as the disease stage according to permanent histopathology...
2016: Oncology Research and Treatment
https://www.readbyqxmd.com/read/27146582/endometrial-injury-may-increase-the-pregnancy-rate-in-patients-undergoing-intrauterine-insemination-an-interventional-randomized-clinical-trial
#19
Ahmed M Bahaa Eldin, Karim H Abdelmaabud, Mohamed Laban, Alaa S Hassanin, Ahmed A Tharwat, Tarek R Aly, Ahmed E Elbohoty, Helmy M Elsayed, Ahmed M Ibrahim, Mohammed E Ibrahim, Haitham M Sabaa, Azza A Abdelrazik, Ibrahim Abdelhady
OBJECTIVE: This study aimed to investigate the effect of endometrial injury using Pipelle catheter in the follicular phase (cycle day 5, 6, or 7) of the stimulation cycle on pregnancy rates in patients undergoing intrauterine insemination. METHODS: This prospective randomized controlled study was carried out in the Assisted Reproductive Technology Unit of Ain Shams University Maternity Hospital, Cairo, Egypt, from July 1, 2013 to August 31, 2015. Three hundred sixty women, 20 to 35 years of age, with patent fallopian tubes, mild male factor infertility, or unexplained infertility were recruited...
October 2016: Reproductive Sciences
https://www.readbyqxmd.com/read/27123198/relationships-between-serum-luteinizing-hormone-level-endometrial-thickness-and-body-mass-index-in-polycystic-ovary-syndrome-patients-with-and-without-endometrial-hyperplasia
#20
Fariba Ramezanali, Gholamreza Khalili, Arezoo Arabipoor, Narges Bagheri Lankarani, Ashraf Moini
BACKGROUND: The endometrial hyperplasia measured by ultrasound in polycystic ovary syndrome (PCOS) women is strongly related to pathologic endometrial thickness, but there is no consensus on the relation between serum luteinizing hormone (LH) and either of these factors: pathologic endometrial hyperplasia and body mass index (BMI). MATERIALS AND METHODS: In this observational cross-sectional study, three hundred fifty infertile PCOS women were involved in this research...
April 2016: International Journal of Fertility & Sterility
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