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Primary spontaneous pneumothorax

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https://www.readbyqxmd.com/read/29312731/does-oxygen-therapy-increase-the-resolution-rate-of-primary-spontaneous-pneumothorax
#1
Chan Beom Park, Mi Hyoung Moon, Hyun Woo Jeon, Deog Gon Cho, Sun Wha Song, Yoo Dong Won, Yong Hwan Kim, Young-Du Kim, Seong Cheol Jeong, Kyung Soo Kim, Si Young Choi
Background: Patients with small pneumothoraces are usually treated with oxygen therapy. However, evidence that oxygen therapy increases resolution rate is based on small populations with secondary spontaneous pneumothorax. Therefore, this study aimed to confirm whether oxygen therapy increases the resolution rate of primary spontaneous pneumothorax (PSP). Methods: We retrospectively reviewed records of patients with PSP who had undergone outpatient observation (room air group) and those who were admitted for oxygen therapy (O2 group) between March 2005 and February 2016...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29290080/burden-between-undersupply-and-overtreatment-in-the-care-of-primary-spontaneous-pneumothorax
#2
Hans-Stefan Hofmann, Tobias Suttner, Reiner Neu, Tobias Potzger, Tamas Szöke, Christian Grosser, Michael Ried
BACKGROUND:  The optimal treatment of primary spontaneous pneumothorax (PSP) is still controversial. The purpose of this study was to analyze the incidence of recurrence, the recurrence-free time, and to identify risk factors for recurrence after PSP. METHODS:  We performed a retrospective analysis of 135 patients with PSP who were treated either conservatively with a chest tube (n = 87) or surgically with video-assisted thoracoscopic surgery (VATS; n = 48) from January 2008 through December 2012...
December 31, 2017: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29288214/familial-pneumothorax-towards-precision-medicine
#3
Rachel M Scott, Elizabeth P Henske, Benjamin Raby, Philip M Boone, Rosemary A Rusk, Stefan J Marciniak
One in 10 patients suffering from primary spontaneous pneumothoraces has a family history of the disorder. Such familial pneumothoraces can occur in isolation, but can also be the presentation of serious genetic disorders with life-threatening vascular or cancerous complications. As the pneumothorax frequently precedes the more dangerous complications by many years, it provides an opportunity to intervene in a focused manner, permitting the practice of precision medicine. In this review, we will discuss the clinical manifestations and underlying biology of the genetic causes of familial pneumothorax...
December 28, 2017: Thorax
https://www.readbyqxmd.com/read/29281936/a-comparative-study-of-hhhfnc-and-ncpap-in-preventing-reintubation-in-extreme-preterm-infants-born-at-less-than-30-week-gestation
#4
W Muhsen, R Roy
INTRODUCTION: Despite recent advances in respiratory support, the wide use of antenatal steroids and surfactant replacement therapy, respiratory problems continue to represent the leading cause of mortality in premature infants during the neonatal period. In the last few years, HHHFNC has been widely adopted as a mode of noninvasive respiratory support for infants with respiratory difficulties. However, data of the safety and efficacy of HHHFNC use in extremely premature infants are scarce...
December 27, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29279462/recurrence-of-spontaneous-pneumothorax-is-not-associated-with-allegedly-risk-prone-lifestyle-conduct
#5
Volker Steger, Ulrike Sostheim, Marcus Leistner, Thorsten Walles
PURPOSE: Spontaneous pneumothorax (PNTX) is a common disease frequently operated at specialized thoracic surgery units. Videothoracoscopic surgery (VATS) has become the standard for treatment and recurrence prevention. While there is broad consensus regarding indications and techniques of PNTX surgery, postoperative risks and consecutive patient behavioral advice have not been sufficiently elucidated. METHODS: Single-center cohort analysis of 641 patients operated for primary PNTX by VATS over 10 years...
December 27, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29277465/optimal-timing-of-video-assisted-thoracoscopic-surgery-for-primary-spontaneous-pneumothorax-in-children
#6
Kibileri Williams, Timothy B Lautz, Astrid H Leon, Tolulope A Oyetunji
PURPOSE: There is no consensus in the pediatric surgical community about when to recommend video-assisted thoracoscopic surgery (VATS) for patients with primary spontaneous pneumothorax (PSP). We aimed to identify factors that predict the likelihood of requiring VATS, and to compare recurrence rates and healthcare utilization among different management approaches to PSP. METHODS: A retrospective chart review and a telephone survey were conducted on all patients 12-21years who were diagnosed with PSP from 2007 to 2015...
November 23, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29216862/the-incidence-and-risk-factors-of-asymptomatic-primary-spontaneous-pneumothorax-detected-during-health-check-ups
#7
Akihisa Mitani, Yukichika Hakamata, Megumi Hosoi, Masafumi Horie, Yoko Murano, Akira Saito, Shintaro Yanagimoto, Shoji Tsuji, Kazuhiko Yamamoto, Takahide Nagase
BACKGROUND: Patients with primary spontaneous pneumothorax (PSP) usually complain of sudden-onset dyspnea and pleuritic chest pain. However, asymptomatic PSP has been incidentally detected on chest X-rays. In this study, we analyzed the incidence, characteristics, risk factors, and prognosis of asymptomatic PSP detected during regular medical check-ups in university students. METHODS: In this study, 101,709 chest X-rays were performed during medical check-ups for students at the University of Tokyo between April 2011 and March 2016...
December 7, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29174248/electrocardiographic-characteristics-in-young-male-patients-with-left-primary-spontaneous-pneumothorax-estimated-by-the-collins-equation
#8
Pang-Yen Liu, Yen-Po Lin, Yi-Hwei Li, Zhi-Wei Su, Chih-Lu Han, Shih-Chung Huang, Chin-Sheng Lin, Fan-Chun Meng, Hsien-Tsai Wu, Gen-Min Lin
OBJECTIVE: To investigate the 12-lead surface electrocardiographic (ECG) findings in young male patients with left primary spontaneous pneumothorax (PSP) estimated by the Collins equation. METHODS: From 2003 through 2008, 60 young male patients who had left PSP and 61 age-matched unaffected males were included for 12-lead ECG analyses. The PSP size was estimated by the Collins equation. Those with left PSP were divided into two groups: 1) large PSP ≥30% (n=37), and 2) small PSP <30% (n=23)...
November 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29155978/results-of-repeated-video-assisted-thoracic-surgery-for-recurrent-pneumothorax-after-primary-spontaneous-pneumothorax
#9
Sukki Cho, Sanghoon Jheon, Dong Kwan Kim, Hyeong Ryul Kim, Dong Myung Huh, Sungsoo Lee, Kyoung Min Ryu, Deog Gon Cho
OBJECTIVES: This study aimed to identify the causes of recurrent pneumothorax and to evaluate the results of repeated video-assisted thoracic surgery (VATS) for recurrent pneumothorax after VATS wedge resection for primary spontaneous pneumothorax (PSP). METHODS: A retrospective review was conducted on 188 patients with recurrent PSP, of a population of 1414 patients who underwent VATS wedge resection for PSP. Reoperations were performed when an air leak persisted longer than 3 days after closed thoracostomy, when a visible bulla of greater than 1 cm on high-resolution computed tomography (HRCT) was observed and when rerecurrence took place after other treatments...
November 16, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29119067/experience-with-ambulatory-management-of-pleural-pathologies-utilizing-small-bore-indwelling-pleural-catheters
#10
Imad-Ud-Din Saqib, Mobeen Iqbal, Atif Rana, Saira Hassan
Introduction Pleural effusion is the excess fluid that accumulates in the pleural space. Pneumothorax is the collection of free air in the pleural cavity, while empyema is the collection of pus in the pleural cavity. Such pleural pathologies pose a great challenge to patients and health care professionals alike. While multiple management options exist, the major portion of it is carried out in the inpatient setting. We sought to evaluate the ambulatory use of indwelling pleural catheters for pleural pathologies, including malignant pleural effusion, empyema, and primary spontaneous pneumothorax...
September 1, 2017: Curēus
https://www.readbyqxmd.com/read/29078667/uniportal-video-assisted-thoracic-surgery-for-pneumothorax-and-blebs-bullae
#11
REVIEW
Luca Bertolaccini, Alessandro Pardolesi, Jury Brandolini, Piergiorgio Solli
The last British Society of Thoracic Surgeons guidelines of 2010 for the management of primary spontaneous pneumothorax (PSP) stated that, after the first recurrence, the treatment of PSP should be a surgical operation, like a bullectomy accompanying with a procedure for inducing pleural adhesions. Therefore, the surgical approach is considered the best treatment to minimise the risk of recurrence in patients who experienced a PSP. There is substantial evidence in the literature demonstrating that the minimally invasive approach should be preferred to the thoracotomic procedure since it can reduce the postoperative pain and it is associated with a faster recovery of the physical and working activity...
2017: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29072869/research-protocol-intravenous-access-during-resuscitation-the-ivar-trial
#12
Pwb Nanayakkara, Y M Smulder
OBJECTIVE: To compare the effects of central versus peripheral drug administration on the rate of return of organised electrical activity and/or spontaneous circulation during CPR. STUDY DESIGN: Randomized clinical trial. STUDY POPULATION: Hospitalized patients and patients presenting at the emergency department, older than 18 years, requiring CPR. INTERVENTION: Central venous access Main study parameters/endpoints: Combined primary endpoint: rate of appearance of organised electrical activity or return of spontaneous circulation...
2017: Acute Medicine
https://www.readbyqxmd.com/read/29067043/surgical-outcome-of-spontaneous-supra-tentorial-intracerebral-hemorrhage
#13
Waqar Aziz Rehman, Muhammad Sohaib Anwar
OBJECTIVE: To assess the risks and benefits of surgical treatment (Open Craniotomy) of Intra-cerebral hematoma (ICH). METHODS: Twenty seven patients of ICH who underwent surgical treatment at Neurosurgical department of Sheikh Zayed Hospital, Rahim Yar Khan, from 1(st) January 2015 to 31(st) December 2015 were included in this study. The primary outcome measured was death and improvement in GCS Status among survivor's at three months. RESULTS: Mean age of the patients was 58...
July 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29038820/-primary-spontaneous-pneumothorax-is-there-an-impact-of-weather-conditions
#14
K Hekmat, C J Bruns
No abstract text is available yet for this article.
October 16, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28970150/flcn-the-causative-gene-for-birt-hogg-dub%C3%A3-syndrome
#15
REVIEW
Laura S Schmidt, W Marston Linehan
Germline mutations in the novel tumor suppressor gene FLCN are responsible for the autosomal dominant inherited disorder Birt-Hogg-Dubé (BHD) syndrome that predisposes to fibrofolliculomas, lung cysts and spontaneous pneumothorax, and an increased risk for developing kidney tumors. Although the encoded protein, folliculin (FLCN), has no sequence homology to known functional domains, x-ray crystallographic studies have shown that the C-terminus of FLCN has structural similarity to DENN (differentially expressed in normal cells and neoplasia) domain proteins that act as guanine nucleotide exchange factors (GEFs) for small Rab GTPases...
January 15, 2018: Gene
https://www.readbyqxmd.com/read/28962820/high-nrf2-expression-in-alveolar-type-i%C3%A2-pneumocytes-is-associated-with-low-recurrences-in-primary-spontaneous-pneumothorax
#16
Yu-Wen Chen, Wen-Chin Chiu, Shah-Hwa Chou, Yu-Han Su, Ying-Fong Huang, Yen-Lung Lee, Shyng-Shiou F Yuan, Yi-Chen Lee
Recurrent primary spontaneous pneumothorax (PSP) is a troublesome problem and a major concern for the patients. This study examined whether nuclear factor erythroid 2-related factor 2 (Nrf2) expression in alveolar type I pneumocytes was associated with the clinical manifestations of PSP patients including disease recurrence. Eighty-eight PSP patients who were managed with needlescopic video-assisted thoracoscopic surgery (NVATS) were included in this study. Immunohistochemistry (IHC) was assessed to determine Nrf2 expression in resected lung tissues and the results were correlated with clinicopathological characteristics by the chi-square or the Fisher's exact test...
October 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28960698/novel-clinical-scoring-system-to-identify-patients-with-pneumothorax-with-suspicion-for-birt-hogg-dub%C3%A3-syndrome
#17
Hiroki Ebana, Teruaki Mizobuchi, Masatoshi Kurihara, Etsuko Kobayashi, Takahiro Haga, Shoichi Okamoto, Kazuhisa Takahashi, Kuniaki Seyama
BACKGROUND AND OBJECTIVE: Birt-Hogg-Dubé syndrome (BHDS) is a rare hereditary disease that presents with multiple lung cysts and pneumothorax (PTX). Although some reports propose that findings from chest computed tomography enable one to distinguish BHDS from primary spontaneous pneumothorax (PSP), it is still unclear whether clinical features are useful for identifying patients with suspicion of BHDS from those with PTX. METHODS: We retrospectively reviewed the medical records of patients with PTX who underwent video-assisted thoracoscopic surgery at Nissan Tamagawa Hospital from January 2012 to December 2015...
September 27, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28932556/expression-of-redox-sensing-factor-nrf2-in-lung-macrophages-and-type-ii-pneumocytes-as-a-prognostic-factor-in-pneumothorax-recurrence
#18
Wen-Chin Chiu, Yen-Lung Lee, Shah-Hwa Chou, Yi-Chen Lee, Yu-Han Su, Yi-An Hou, Hung-Hsing Chiang, Hsin-Ling Yin, Stephen Chu-Sung Hu, Ming-Yii Huang, Chih-Jen Huang, Shyng-Shiou F Yuan
BACKGROUND: Primary spontaneous pneumothorax (PSP) is a common clinical problem. However, PSP recurrence is still a major concern. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays a protective role against oxidative airway diseases. The aim was to investigate the role of Nrf2 in PSP patients and its correlation with recurrence. METHODS: Eighty-nine patients were enrolled and received wedge resection of lung with identifiable blebs. Nrf2 expression in resected lung tissues was determined by immunohistochemistry (IHC) and correlated with clinicopathological variables...
August 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28881006/simple-aspiration-versus-intercostal-tube-drainage-for-primary-spontaneous-pneumothorax-in-adults
#19
REVIEW
Kristin V Carson-Chahhoud, Abel Wakai, Joseph Em van Agteren, Brian J Smith, Grainne McCabe, Malcolm P Brinn, Ronan O'Sullivan
BACKGROUND: For management of pneumothorax that occurs without underlying lung disease, also referred to as primary spontaneous pneumothorax, simple aspiration is technically easier to perform than intercostal tube drainage. In this systematic review, we seek to compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax. This review was first published in 2007 and was updated in 2017. OBJECTIVES: To compare the clinical efficacy and safety of simple aspiration versus intercostal tube drainage for management of primary spontaneous pneumothorax...
September 7, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28874036/relationship-between-onset-of-spontaneous-pneumothorax-and-weather-conditions
#20
Taijiro Mishina, Atsushi Watanabe, Masahiro Miyajima, Junji Nakazawa
OBJECTIVES: Spontaneous pneumothorax (SP) results from the rupture of blebs or bullae. It has been suggested that changes in weather conditions may trigger the onset of SP. Our aim was to examine the association between the onset of primary SP with weather changes in the general population in Sapporo, Japan. METHODS: From January 2008 through September 2013, 345 consecutive cases with a diagnosis of primary SP were reviewed. All cases of primary SP developed in the area within 40 km from the Sapporo District Meteorological Observatory...
September 1, 2017: European Journal of Cardio-thoracic Surgery
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