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Primary spontaneous pneumothorax

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https://www.readbyqxmd.com/read/28088269/association-of-mmp-2-and-mmp-9-expression-with-recurrences-in-primary-spontaneous-pneumothorax
#1
Ying-Fong Huang, Wen-Chin Chiu, Shah-Hwa Chou, Yu-Han Su, Yu-Wen Chen, Chee-Yin Chai, Chih-Jen Huang, Ming-Yii Huang, Shyng-Shiou F Yuan, Yi-Chen Lee
Primary spontaneous pneumothorax (PSP) is a common benign problem. However, PSP recurrence is still a troublesome complication for most patients. This study intended to determine the role of matrix metalloproteinase-2 (MMP-2) and MMP-9 in type II pneumocytes of patients with PSP and its relation with recurrence. Ninety-one patients who had undergone needlescopic video-assisted thoracoscopic surgery wedge resection of lung with identifiable blebs for PSP were included in this study. Immunohistochemical (IHC) staining was used to measure the expression of MMP-2 and MMP-9 in lung tissues of PSP patients...
January 2017: Kaohsiung Journal of Medical Sciences
https://www.readbyqxmd.com/read/28066601/postoperative-predictors-of-ipsilateral-and-contralateral-recurrence-in-patients-with-primary-spontaneous-pneumothorax
#2
Ying-Yi Chen, Hsu-Kai Huang, Hung Chang, Shih-Chun Lee, Tsai-Wang Huang
BACKGROUND: Preventive surgery for contralateral recurrence of primary spontaneous pneumothorax (PSP) remains controversial and few studies discussed both ipsilateral and contralateral recurrences simultaneously. Thus, we aimed to identify the predictors of ipsilateral and contralateral PSP recurrence and to review literatures on the association of blebs/bullae on HRCT with PSP recurrence. METHODS: We retrospectively reviewed consecutive patients who were treated at our hospital for first recurrence of PSP between January 2001 and December 2005...
November 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27995774/occult-primary-pulmonary-synovial-sarcoma-presenting-as-recurrent-spontaneous-pneumothorax-and-explosive-progression
#3
Chenglin Guo, Chengwu Liu, Qiang Pu, Feng Lin, Lunxu Liu
Primary pulmonary synovial sarcoma (PPSS) is a relatively rare neoplasm with highly progressive potential. We present an extremely rare case of PPSS presenting as recurrent pneumothorax with bullous lesions. Bullectomy was performed at the local hospital. Unfortunately, the patient was initially misdiagnosed as atypical carcinoid. Although a negative resection margin was obtained during the first surgery and a remedial operation and chemotherapy followed, the patient developed severe disease progression and died soon after...
December 20, 2016: Thoracic Cancer
https://www.readbyqxmd.com/read/27986981/-pulmonary-causes-of-chest-pain
#4
B Jany
Chest pain represents one of the most frequent symptoms of pulmonary diseases, in addition to dyspnea and cough. The broad differential diagnostics include the intensely painful but prognostically benign acute pleurisy as well as potentially life-threatening events, such as acute pulmonary embolism or malignant chest diseases. Primary spontaneous pneumothorax is characterized by acute chest pain. Pain associated with a respiratory infection, such as pneumonia rarely poses a difficult diagnostic problem. Painful diseases of the lungs can be differentiated in an initial approach by asking the patient if the pain is related to breathing, which is characteristic of pleuritic chest diseases...
December 16, 2016: Der Internist
https://www.readbyqxmd.com/read/27938546/-soft-tissue-angiosarcoma-with-pulmonary-metastases-case-report-and-literature-review
#5
X L Mu, Z X Wu, H J Liang, Z Wang, X Fang, D H Yang, Z L Cao, Z C Gao
Objective: To investigate the differential diagnosis between pulmonary metastases from soft-tissue angiosarcoma and primary pulmonary angiosarcoma. Methods: A case of soft-tissue angiosarcoma with pulmonary metastases was reported and related literatures were reviewed. Results: A 39 year-old man complaining of hemoptysis, cough, and sputum for 10 months was admitted to our hospital in September 2013. He was initially diagnosed as having primary pulmonary angiosarcoma after wedge-resection biopsy of the lung...
December 12, 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27909813/outcome-and-risk-factors-of-recurrence-after-thoracoscopic-bullectomy-in-young-adults-with-primary-spontaneous-pneumothorax
#6
Takashi Nakayama, Yusuke Takahashi, Hirofumi Uehara, Noriyuki Matsutani, Masafumi Kawamura
PURPOSE: To investigate the risk factors of recurrence of pneumothorax following thoracoscopic bullectomy in young adults. METHODS: Between January, 2005 and September, 2015, 167 patients aged ≤40 years underwent initial thoracoscopic bullectomy for primary spontaneous pneumothorax (PSP) at our hospital. Recurrence-free probability was calculated from the date of surgery to recurrence or last follow-up, using the Kaplan-Meier method. RESULTS: Sixteen (9...
December 1, 2016: Surgery Today
https://www.readbyqxmd.com/read/27909771/association-between-bmi-and-recurrence-of-primary-spontaneous-pneumothorax
#7
Juntao Tan, Yang Yang, Jianhong Zhong, Chuantian Zuo, Huamin Tang, Huimin Zhao, Guang Zeng, Jianfeng Zhang, Jianji Guo, Nuo Yang
BACKGROUND: Whether body mass index (BMI) is a significant risk factor for recurrence of primary spontaneous pneumothorax (PSP) remains controversial. The purpose of this study was to examine whether BMI and other factors are linked to risk of PSP recurrence. METHODS: A consecutive cohort of 273 patients was retrospectively evaluated. Patients were divided into those who experienced recurrence (n = 81) and those who did not (n = 192), as well as into those who had low BMI (n = 75) and those who had normal or elevated BMI (n = 198)...
December 1, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27867569/does-11-5-mm-guided-single-port-surgery-has-clinical-advantage-than-multi-port-thoracoscopic-surgery-in-spontaneous-pneumothorax
#8
Hyun Woo Jeon, Young-Du Kim
BACKGROUND: Video-assisted thoracoscopic surgery (VATS) has been widely used for spontaneous pneumothorax (SP). In recent years, thoracic surgeons have attempted single incision or single port surgery with the development of surgical technology and skills. Theoretically, single port surgery is expected to provide benefits such as less pain and early recovery. The purpose of this study was to determine the benefits of single port surgery in SP. METHODS: The 107 patients with SP who underwent surgery, between July 2013 and May 2015, were reviewed retrospectively...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27821828/-primary-spontaneous-pneumothorax-with-an-azygos-lobe
#9
Shoji Nakata, Shin Satake, Yoshitomo Okumura, Satoshi Hara, Kyongyob Min, Keiko Nakayama
A-21-year old man presented with dyspnea and a chest radiograph showed a right pneumothorax. Chest computed tomography revealed a collapsed lung and floating membrane, which was the lowermost part as a tear-shaped shadow. After the chest tube was inserted and surgical management was performed using a video-assisted thoracoscopic approach. At surgery, the visceral and parietal layers of pleura forming the mesoazygos were not fused, and azygos vein had a partial mobility. There was no adhesion between an upper lobe and visceral pleura...
November 2016: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/27785139/selected-metabolic-aspects-of-elastin-and-collagen-fiber-proteolysis-in-diseases-of-the-respiratory-system-the-significance-of-%C3%AE-1-antitrypsin-deficiency
#10
Agata Dżeljilji, Wojciech Rokicki, Krzysztof Karuś
The process of elastin and collagen fiber destruction was presented based on the example of the changes taking place in the course of chronic obstructive pulmonary disease and primary spontaneous pneumothorax. In 1963, when analyzing patients with α1 antitrypsin deficiency, Dr Laurell and Dr Eriksson hypothesized that elastolysis plays a role in the pathogenesis of emphysema, which marked the beginning of studies aimed at analyzing this process. The present work concerns new scientific reports regarding the hypothesis...
September 2016: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/27775299/-spontaneous-pneumothorax-in-children-factors-associated-with-their-recurrence
#11
P Jiménez Arribas, S López-Fernández, A Laín Fernández, G Guillén Burrieza, J Lloret Roca
INTRODUCTION: Recurrence of spontaneous pneumothorax (SP) is more frequent in pediatric patients. The purpose of our study was to identify factors associated with this recurrence. MATERIAL AND METHODS: Retrospective review of the chart of patients with SP treated at our institution between 2004 and 2014. Statistic methods (χ2 and logistic regression) were used analyzing age, gender, side and size of pneumothorax and therapeutic approach as possible predictive factors of SP recurrence...
October 10, 2015: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/27737563/chest-computed-tomographic-image-screening-for-cystic-lung-diseases-in-patients-with-spontaneous-pneumothorax-is-cost-effective
#12
Nishant Gupta, Dale Langenderfer, Francis X McCormack, Daniel P Schauer, Mark H Eckman
RATIONALE: Patients without a known history of lung disease presenting with a spontaneous pneumothorax are generally diagnosed as having primary spontaneous pneumothorax. However, occult diffuse cystic lung diseases such as Birt-Hogg-Dubé syndrome (BHD), lymphangioleiomyomatosis (LAM), and pulmonary Langerhans cell histiocytosis (PLCH) can also first present with a spontaneous pneumothorax, and their early identification by high-resolution computed tomographic (HRCT) chest imaging has implications for subsequent management...
January 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27650627/a-novel-flcn-c-1489_1490deltg-mutation-that-escapes-the-nonsense-mediated-decay-system
#13
Yong-Jin Park, Seog-Ki Lee, Seong-Ho Kang, Sook-Jin Jang, Dae-Soo Moon, Geon Park
A novel FLCN c.1489_1490delTG (p.Val497Glyfs*22) mutation at the genomic DNA and mRNA levels was identified in a 43-year-old woman with complaining of recurrent primary spontaneous pneumothorax. The aberrant FLCN mRNA escaped the nonsense-mediated decay system (NMD) because of a premature termination code located in an NMD-incompetent region. To the best of our knowledge, this is the first case report of an FLCN mutation escaping the NMD.
September 2016: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/27642566/primary-spontaneous-pneumothorax-due-to-high-bleb-burden
#14
Justin M Segraves, Megan M Dulohery
Primary spontaneous pneumothorax (PSP) occurs most frequently in young, tall, lean, male smokers without any known underlying lung disease. It is an important diagnosis to make promptly in order to prevent progression to obstructive shock. We present a case report of a young, male, former-smoker and polysubstance abuser with no prior lung history that developed acute dyspnea at rest and was found to have a large right pneumothorax on chest x-ray. A pig-tail catheter was utilized, but his course was complicated by a recurrent tension pneumothorax...
2016: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/27625060/study-protocol-for-a-randomised-controlled-trial-of-invasive-versus-conservative-management-of-primary-spontaneous-pneumothorax
#15
Simon G A Brown, Emma L Ball, Kyle Perrin, Catherine A Read, Stephen E Asha, Richard Beasley, Diana Egerton-Warburton, Peter G Jones, Gerben Keijzers, Frances B Kinnear, Ben C H Kwan, Y C Gary Lee, Julian A Smith, Quentin A Summers, Graham Simpson
INTRODUCTION: Current management of primary spontaneous pneumothorax (PSP) is variable, with little evidence from randomised controlled trials to guide treatment. Guidelines emphasise intervention in many patients, which involves chest drain insertion, hospital admission and occasionally surgery. However, there is evidence that conservative management may be effective and safe, and it may also reduce the risk of recurrence. Significant questions remain regarding the optimal initial approach to the management of PSP...
September 13, 2016: BMJ Open
https://www.readbyqxmd.com/read/27618441/ultrasonic-technology-for-management-of-primary-spontaneous-pneumothorax
#16
Alfonso Fiorelli, Antonio Mazzella, Marina Accardo, Mario Santini
To manage primary spontaneous pneumothorax, we use an alternative technique for bleb resection and we induce pleurodesis with an ultrasonic-driven scalpel. This technique was successfully performed in nine consecutive patients with primary spontaneous pneumothorax with small (<20 mm) and limited number of blebs (<2) and without significant underlying lung disease. After identification of air leakage, the jaws of the instrument were clamped onto the bleb and included a margin of normal lung. Power level 3 energy was applied to resect the bleb and to seal the parenchyma...
September 12, 2016: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/27601265/modified-chest-wall-pulley-for-lung-excision-during-single-incision-thoracoscopic-surgery-for-primary-spontaneous-pneumothorax
#17
Kenji Tsuboshima, Machiko Nagata, Teppei Wakahara, Yasumi Matoba, Yoshimasa Maniwa
We reported the feasibility of single-incision thoracoscopic surgery bullectomy using a chest wall pulley for lung excision (PulLE) in patients with primary spontaneous pneumothorax (PSP). PulLE has many merits including comfort of manipulation, cosmetic advantages, etc., compared to other procedures. However, our method was utilized for relatively straightforward cases. The PulLE was contraindicated for PSPs with multiple or comprehensive bullae. Therefore, we developed the modified PulLE (mPulLE) to treat such cases in February 2015...
December 20, 2016: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27542625/another-innovation-in-surgery-for-primary-spontaneous-pneumothorax-for-men-only
#18
EDITORIAL
Michael K Hsin
No abstract text is available yet for this article.
October 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/27515837/learning-curve-of-single-incision-thoracoscopic-surgery-for-primary-spontaneous-pneumothorax
#19
Hee Chul Yang, Sohee Kim, Sungwon Yum, Sukki Cho, Kwhanmien Kim, Sanghoon Jheon
BACKGROUND: Single-incision thoracoscopic surgery (SITS) requires extensive time and practice to achieve satisfactory technical skills. The aim of this study was to evaluate the learning curves of SITS for primary spontaneous pneumothorax (PSP). METHODS: This study included a total of 274 consecutive patients who underwent PSP surgery by a single operator between May 2011 and February 2014. During this period, SITS was applied as a routine approach. Learning curves were made by the cumulative sum (CUSUM) method using the number of cases and four surgical technique-related factors, including operation time, postoperative complication, non-SITS rate, and ipsilateral PSP recurrence...
August 11, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27507173/a-systematic-review-of-the-respiratory-effects-of-inhalational-marijuana
#20
REVIEW
Mary P Martinasek, Jamie B McGrogan, Alisha Maysonet
This systematic review focuses on respiratory effects of inhalational marijuana. The systematic review of the literature was conducted using a comparative method between 2 researchers. Abstracts were reviewed for inclusion of respiratory effects related to inhalational marijuana. Relevant abstracts were collected, and full text articles were retrieved for review. Articles were removed if they did not contain burning marijuana; were animal studies; or were editorials, systematic reviews, commentaries, non-English language, or non-respiratory-related articles...
November 2016: Respiratory Care
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