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Excessive central airway collapse

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https://www.readbyqxmd.com/read/27764007/teflon-injection-into-the-trachea-causes-predictable-fibroblastic-response-and-collagen-deposition-a-pilot-study
#1
Javier A Longoria, Miwa Fujiwara, Catalina Guerra, Jeffrey L Lee, Catherine S H Sassoon, Farhad Mazdisnian
BACKGROUND: Expiratory central airway collapse is an increasingly recognized abnormality of the central airways and may be present in as many as 22% of patients evaluated for chronic obstructive pulmonary disease and/or asthma. Many current treatment options require invasive procedures that have been shown to cause significant morbidity and mortality. To test the hypothesis that Teflon injection will induce sufficient fibroblast proliferation and collagen deposition, we evaluated the time course on the effect of Teflon injection in the posterior membranous trachea on the histopathology of the tracheobronchial tree...
October 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/27058715/awareness-competencies-and-practice-patterns-in-tracheobronchomalacia-a-survey-of-pulmonologists
#2
Ismael Matus, William Richter, Sriniwasan B Mani
BACKGROUND: Tracheobronchomalacia (TBM) is a disorder of expiratory central airway collapse. TBM is separate from excessive dynamic airway collapse. Historically TBM has lacked a universally accepted definition. No consensus recommendations on evaluation and management exist. We suspect these unresolved issues contribute to deficits in pulmonologists' awareness and management of TBM. METHODS: We created a 20-question survey obtaining information about overall awareness, knowledge base, competencies, and practice patterns in managing TBM...
April 2016: Journal of Bronchology & Interventional Pulmonology
https://www.readbyqxmd.com/read/26508945/successful-high-flow-nasal-oxygen-therapy-for-excessive-dynamic-airway-collapse-a-case-report
#3
Jisoo Park, Yeon Joo Lee, Se Joong Kim, Jong Sun Park, Ho Il Yoon, Jae Ho Lee, Choon-Taek Lee, Young-Jae Cho
Excessive dynamic airway collapse (EDAC) is a disease entity of excessive reduction of the central airway diameter during exhalation, without cartilage collapse. An 80-year-old female presented with generalized edema and dyspnea at our hospital. The patient was in a state of acute decompensated heart failure due to pneumonia with respiratory failure. We accordingly managed the patient with renal replacement therapy, mechanical ventilation and antibiotics. Bronchoscopy confirmed the diagnosis of EDAC. We scheduled extubation after the improvement of pneumonia and heart condition...
October 2015: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/26182150/counterpoint-is-the-apnea-hypopnea-index-the-best-way-to-quantify-the-severity-of-sleep-disordered-breathing-no
#4
EDITORIAL
Naresh M Punjabi
No abstract text is available yet for this article.
January 2016: Chest
https://www.readbyqxmd.com/read/26167306/excessive-dynamic-airway-collapse-an-unexpected-contributor-to-respiratory-failure-in-a-surgical-patient
#5
Michael R Lyaker, Victor R Davila, Thomas J Papadimos
Central airway collapse plays a significant, underrecognized role in respiratory failure after extubation of critically ill patients. Historically, airway collapse has been attributed to tracheomalacia (TM), softening of the cartilage in the trachea and other large airways. More recently, excessive dynamic airway collapse (EDAC) has been described as a distinct process unrelated to a loss of cartilaginous airway support. EDAC is caused by the posterior wall of the trachea bulging forward and causing airway obstruction during exhalation...
2015: Case Reports in Anesthesiology
https://www.readbyqxmd.com/read/25973669/patients-with-obstructive-sleep-apnea-at-altitude
#6
REVIEW
Konrad E Bloch, Tsogyal D Latshang, Silvia Ulrich
Bloch, Konrad E., Tsogyal D. Latshang, and Silvia Ulrich. Patients with obstructive sleep apnea at altitude. High Alt Med Biol 16:110-116, 2015.--Obstructive sleep apnea (OSA) is highly prevalent in the general population, in particular in men and women of older age. In OSA patients sleeping near sea level, the apneas/hypopneas associated with intermittent hypoxemia are predominantly due to upper airway collapse. When OSA patients stay at altitudes above 1600 m, corresponding to that of many tourist destinations, hypobaric hypoxia promotes frequent central apneas in addition to obstructive events, resulting in combined intermittent and sustained hypoxia...
June 2015: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/25962857/paediatric-tracheomalacia
#7
REVIEW
Erik B Hysinger, Howard B Panitch
Intrathoracic tracheomalacia is characterized by increased compliance of the central airway within the thorax. This leads to excessive dynamic collapse during exhalation or periods of increased intrathoracic pressure such as crying. Extrathoracic tracheomalacia involves dynamic collapse of the airway between the glottis and sternal notch that occurs during inhalation rather than exhalation. The tone of the posterior membrane of the trachea increases throughout development and childhood, as does the rigidity of the tracheal cartilage...
January 2016: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/25829963/excessive-dynamic-airway-collapse-in-a-small-cohort-of-chronic-obstructive-pulmonary-disease-patients
#8
C Represas-Represas, V Leiro-Fernández, R Mallo-Alonso, M I Botana-Rial, A Tilve-Gómez, A Fernández-Villar
INTRODUCTION: The prevalence of EDAC (Excessive Dynamic Airway Collapse) has not been studied specifically in patients with chronic obstructive pulmonary disease (COPD). OBJECTIVE: The aim of this study was to investigate the prevalence of EDAC in COPD and to determine whether there are clinical factors or functional variables that could influence the degree of expiratory collapse of central airways. METHODS: Prospective observational study of a group of patients with COPD...
April 2015: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/25721828/flat-trachea-syndrome-a-rare-condition-with-symptoms-similar-to-obstructive-airway-disease
#9
Mohammed Akil D Gani, Vanessa J C Rogers, Khalid H Sachak, Joseph F K Marzouk
Flat trachea syndrome, commonly known as 'tracheobronchomalacia', is a central airway disease characterised by excessive expiratory collapse of the tracheobronchial posterior membrane due to weakness in the airway walls. Patients present with symptoms such as chronic cough, dyspnoea and recurrent respiratory tract infections, which are often attributed to more common conditions such as asthma and chronic obstructive pulmonary disease (COPD). The term 'Flat Trachea Syndrome' was first proposed by Niranjan and Marzouk in 2010 following a retrospective study of 28 patients with the condition who underwent surgery for it...
2015: BMJ Case Reports
https://www.readbyqxmd.com/read/24381188/severe-excessive-dynamic-airway-collapse-in-a-patient-with-primary-sj%C3%A3-gren-s-syndrome
#10
Sophie Ismael, Delphine Wermert, Kim-Diep Dang-Tran, Marion Venot, Jean-Yves Fagon, Jean-Luc Diehl
Airway and cystic lung diseases can be observed in patients with Sjögren's syndrome. We report a case of such a patient suffering from respiratory failure due to recurrent episodes of right pneumothorax, requiring invasive mechanical ventilation. Despite thoracic drainage and adequate pneumothorax management, the patient could not be weaned from the ventilator. Fiberoptic bronchoscopy revealed severe central excessive dynamic airway collapse of the lower part of the trachea and proximal bronchi. The severity of airway collapse was maximal at the intermediate bronchus level, with a near-complete obstruction during expiration...
October 2014: Respiratory Care
https://www.readbyqxmd.com/read/23993822/tracheobronchomalacia-and-excessive-dynamic-airway-collapse
#11
REVIEW
Septimiu Murgu, Henri Colt
Tracheobronchomalacia and excessive dynamic airway collapse are morphologic types of expiratory central airway collapse with specific pathophysiology, cause, and structural changes in airway wall. Physicians caring for symptomatic patients with expiratory central airway collapse must localize the flow-limiting airway segments amenable to bronchoscopic or surgical interventions. Functional bronchoscopy and dynamic radiologic studies are performed for the initial evaluation and to design follow-up strategies...
September 2013: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/23676959/obstructive-sleep-apnea-hypopnea-syndrome
#12
REVIEW
W De Backer
Obstructive sleep apnea/hypopnea syndrome (OSAHS) is characterized by recurrent episodes of partial or complete upper airway collapse during sleep that is highlighted by a reduction in, or complete cessation of, airflow despite documented on going inspiratory efforts. Due to the lack of adequate alveolar ventilation that results from the upper airway narrowing, oxygen saturation may drop and partial pressure of CO2 may occasionally increase. The events are mostly terminated by arousals. Clinical consequences are excessive daytime sleepiness related to the sleep disruption...
June 2013: Panminerva Medica
https://www.readbyqxmd.com/read/23598953/spirometer-controlled-cine-magnetic-resonance-imaging-used-to-diagnose-tracheobronchomalacia-in-paediatric-patients
#13
Pierluigi Ciet, Piotr Wielopolski, Rashindra Manniesing, Sandra Lever, Marleen de Bruijne, Giovanni Morana, Pier Carlo Muzzio, Maarten H Lequin, Harm A W M Tiddens
Tracheobronchomalacia (TBM) is defined as an excessive collapse of the intrathoracic trachea. Bronchoscopy is the gold standard for diagnosing TBM; however it has major disadvantages, such as general anaesthesia. Cine computed tomography (CT) is a noninvasive alternative used to diagnose TBM, but its use in children is restricted by ionising radiation. Our aim was to evaluate the feasibility of spirometer-controlled cine magnetic resonance imaging (MRI) as an alternative to cine-CT in a retrospective study...
January 2014: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/23074483/polysomnography-in-patients-with-obstructive-sleep-apnea-an-evidence-based-analysis
#14
(no author information available yet)
OBJECTIVE: The objective of this health technology policy assessment was to evaluate the clinical utility and cost-effectiveness of sleep studies in Ontario. CLINICAL NEED: TARGET POPULATION AND CONDITION Sleep disorders are common and obstructive sleep apnea (OSA) is the predominant type. Obstructive sleep apnea is the repetitive complete obstruction (apnea) or partial obstruction (hypopnea) of the collapsible part of the upper airway during sleep. The syndrome is associated with excessive daytime sleepiness or chronic fatigue...
2006: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/22426568/tracheobronchomalacia-in-children-review-of-diagnosis-and-definition
#15
REVIEW
Judith Zhi Yie Tan, Michael Ditchfield, Nicholas Freezer
Tracheobronchomalacia is characterised by excessive airway collapsibility due to weakness of airway walls and supporting cartilage. The standard definition requires reduction in cross-sectional area of at least 50% on expiration. However, there is a paucity of information regarding the normal range of central airway collapse among children of varying ages, ethnicities and genders, with and without coexisting pulmonary disease. Consequently, the threshold for pathological collapse is considered somewhat arbitrary...
August 2012: Pediatric Radiology
https://www.readbyqxmd.com/read/22023094/obesity-and-obstructive-sleep-apnoea-mechanisms-for-increased-collapsibility-of-the-passive-pharyngeal-airway
#16
REVIEW
Shiroh Isono
Epidemiological evidence suggests there are significant links between obesity and obstructive sleep apnoea (OSA), with a particular emphasis on the importance of fat distribution in the development of OSA. In patients with OSA, the structure of the pharyngeal airway collapses. A collapsible tube within a rigid box collapses either due to decreased intraluminal pressure or increased external tissue pressure (i.e. reduction in transmural pressure), or due to reduction in the longitudinal tension of the tube. Accordingly, obesity should structurally increase the collapsibility of the pharyngeal airway due to excessive fat deposition at two distinct locations...
January 2012: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/21868463/central-airway-stabilization-for-tracheobronchomalacia-improves-quality-of-life-in-patients-with-copd
#17
Armin Ernst, David D Odell, Gaetane Michaud, Adnan Majid, Felix F J Herth, Sidhu P Gangadharan
BACKGROUND: Tracheobronchomalacia (TBM) is characterized by excessive collapsibility of the central airways, typically during expiration. TBM may be present in as many as 50% of patients evaluated for COPD. The impact of central airway stabilization on symptom pattern and quality of life is poorly understood in this patient population. METHODS: Patients with documented COPD were identified from a cohort of 238 patients assessed for TBM at our complex airway referral center...
November 2011: Chest
https://www.readbyqxmd.com/read/20799999/what-is-central-sleep-apnea
#18
REVIEW
Atul Malhotra, Robert L Owens
Central sleep apnea (CSA) describes a group of conditions in which cessations in air flow occur without respiratory effort. In contrast, obstructive sleep apnea patients have ongoing respiratory effort during respiratory events. However, considerable overlap exists in the pathogenesis and clinical presentation of obstructive sleep apnea and CSA. A good working knowledge of the mechanisms underlying CSA is important for optimal clinical care. In general, CSA can be classified into those with excessive drive (eg, Cheyne-Stokes breathing) versus those with inadequate drive (eg, sleep hypoventilation syndrome)...
September 2010: Respiratory Care
https://www.readbyqxmd.com/read/20427921/obstructive-sleep-apnea-and-its-management
#19
REVIEW
C Sunitha, S Aravind Kumar
Obstructive sleep apnea (OSA) is an increasingly common disorder. It is characterized by frequent episodes of airway obstruction associated with a reduced caliber of the upper airway and is vulnerable to further narrowing and collapse. Acute and repetitive effects of apnea and hypopnea include oxygen desaturation, reduction in intrathoracic pressure, excessive daytime sleepiness, impaired executive function and central nervous system arousals. The apnea-hypopnea index and respiratory distress index help quantify the severity of the condition...
January 2010: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/20139577/obstructive-sleep-apnea-clinical-and-diagnostic-features
#20
REVIEW
C Sunitha, S Aravindkumar
Obstructive sleep apnea (OSA) is an increasingly common disorder. It is characterized by frequent episodes of airway obstruction associated with a reduced caliber of the upper airway and is vulnerable to further narrowing and collapse. Acute and repetitive effects of apnea and hypopnea include oxygen desaturation, reduction in intrathoracic pressure, excessive daytime sleepiness, impaired executive function and central nervous system arousals. The apnea-hypopnea index and respiratory distress index help quantify the severity of the condition...
October 2009: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
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