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Bronchial stenosis

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https://www.readbyqxmd.com/read/27916370/tanshinone-iia-attenuates-epithelial-mesenchymal-transition-to-inhibit-the-tracheal-narrowing
#1
Hongtao Duan, Lijie Ma, Honggang Liu, Yong Zhang, Zhipei Zhang, Xiaolong Yan, Xiaofei Li
BACKGROUND: This study examines the effects of tanshinone IIA (TIIA) on epithelial-mesenchymal transition (EMT) in tracheal transplantation and the ability of TIIA to inhibit tracheal narrowing after tracheal transplantation. Mechanisms that may be involved in this process are also explored. METHODS: Human bronchial epithelial cells were treated in vitro with TGF-β1 for 72 h. The cells were pretreated with TIIA (40 μg/mL) or DMSO for 2 h before TGF-β1 stimulation...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27893684/ct-findings-of-small-cell-lung-carcinoma-can-recognizable-features-be-found
#2
Dongjun Lee, Ji Young Rho, Seunghun Kang, Koun Joy Yoo, Hye Jeong Choi
The purpose of this study was to clarify the recognizable computed tomography (CT) features of small cell lung carcinoma (SCLC).Contrast enhanced CT scans were reviewed retrospectively for mass location, mediastinal extension, and other concomitant findings in 142 patients with pathologically proven SCLC. SCLC was classified into hilar mass only (type I), hilar mass with ipsilateral mediastinal extension (type II), hilar mass with bilateral mediastinal extension (type III), and peripheral mass (type IV). When mediastinal lymphadenopathy (m-LAP) was indistinguishable from a hilar mass, we defined it as a mediastinal conglomerate mass (m-CM)...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27863670/selection-and-fabrication-of-a-non-woven-polycarbonate-urethane-cover-for-a-tissue-engineered-airway-stent
#3
Weiluan Chen, Johanna Clauser, Anja Lena Thiebes, Donnacha J McGrath, Peter E McHugh, Ulrich Steinseifer, Stefan Jockenhoevel, Wim E Hennink, Robbert Jan Kok
One of the major problems in end-stage bronchotracheal cancer is stenosis of the upper airways, either due to luminal ingrowth of the tumor or mucus plugging. Airway stents that suppress tumor ingrowth and sustain mucociliary transport can alleviate these problems in end-stage bronchial cancer. We evaluated different types of polymeric covers for a tissue engineered airway stent. The distinguishing feature of this stent concept is that respiratory epithelial cells can grow on the luminal surface of the stent which facilitates mucociliary clearance...
November 30, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/27812639/prominent-bronchial-vasculature-hemoptysis-and-bilateral-ground-glass-opacities-in-a-young-woman-with-mitral-stenosis
#4
Fabian Aigner, Rudolf Speich, Macé Matthew Schuurmans
No abstract text is available yet for this article.
September 2016: Jornal Brasileiro de Pneumologia: Publicaça̋o Oficial da Sociedade Brasileira de Pneumologia e Tisilogia
https://www.readbyqxmd.com/read/27766409/laser-tracheobronchoplasty-a-novel-technique-for-the-treatment-of-symptomatic-tracheobronchomalacia
#5
Paul Castellanos, Manjunath Mk, Ihab Atallah
The management of tracheobronchomalacia is a very challenging problem with few treatment options. This study aims to evaluate the outcomes of a novel surgical treatment for membranous tracheobronchomalacia. A consecutive series of patients with tracheobronchomalacia were treated with two to three holmium laser scarring surgeries of the hyperdynamic tracheal and bronchial walls for the purpose of stiffening them through fibrosis. Patients filled out a Dyspnea Index questionnaire before and after treatment. Ten patients were treated for their tracheobronchomalacia with a mean age of 54 years...
October 20, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27756350/two-port-approached-thoracoscopic-carina-reconstruction-using-natural-bronchial-bifurcation
#6
Tong Qiu, Yandong Zhao, Jianfang Song, Bo Fu, Yunpeng Xuan, Wenjie Jiao
BACKGROUND: Carina resection and reconstruction is a challenging procedure for thoracic surgeons. We describe a novel technique of thoracoscopic carina reconstruction using the natural bifurcation, following pulmonary resection of the lung neoplasm. To our knowledge, it is the first report of this kind. CASE PRESENTATION: A 71-year-old male diagnosed of squamous cell lung cancer received two-port approached video-assisted thoracoscopic right bilobectomy with carina resection after 2 cycles of neoadjuvant therapy...
October 18, 2016: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/27703342/chronic-pseudomonas-aeruginosa-infection-induced-chronic-bronchitis-and-emphysematous-changes-in-ccsp-deficient-mice
#7
Takemasa Matsumoto, Masaki Fujita, Ryosuke Hirano, Junji Uchino, Yukari Tajiri, Satoru Fukuyama, Yasuo Morimoto, Kentaro Watanabe
The club cell secretory protein (CCSP) is a regulator of lung inflammation following acute respiratory infection or lung injury. Recently, the relationship between CCSP and COPD has been reported. Since COPD results from an abnormal inflammatory response, we hypothesized that CCSP could have a protective role against chronic inflammation-induced lung damage. To address this issue, the pathophysiology of chronic lung inflammation induced by Pseudomonas aeruginosa in CCSP-deficient mice was determined. A tube of 5 mm in length was soaked in a fluid containing P...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27662476/the-application-of-liquid-nitrogen-spray-cryotherapy-in-treatment-of-bronchial-stenosis
#8
Kelly J Janke, Abbas El-Sayed Abbas, Vishnu Ambur, Daohai Yu
OBJECTIVE: Spray cryotherapy (SCT), the application of liquid nitrogen in a noncontact form, has been demonstrated to have efficacy in treating various types of pathologic lesions of the airway when used as an adjunct with bronchoscopy. The purpose of the study was to evaluate the results of the use of bronchoscopic SCT on the airway in a single institution. METHODS: We performed a retrospective review of data collected on all patients who underwent SCT to re-establish or improve airway patency in an 11-month period...
September 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27621904/evaluation-of-airway-resistance-in-primary-small-cell-carcinoma-of-the-trachea-by-mostgraph-a-case-study
#9
Eri Hagiwara, Yasuhiro Gon, Kentaro Hayashi, Mai Takahashi, Yuko Iida, Hisato Hiranuma, Yoshiko Nakagawa, Tsukasa Hataoka, Kenji Mizumura, Shuichiro Maruoka, Tetsuo Shimizu, Noriaki Takahashi, Shu Hashimoto
The case subject was a 58-year-old woman who presented to our hospital with a chief complaint of respiratory discomfort. Wheezing could be heard in both lungs; treatment was initiated with inhaled steroids for suspected bronchial asthma. However, 1 week later, the respiratory discomfort had not improved and the wheezing sound had progressed to the neck area. Upper airway obstruction was suspected; therefore, chest computed tomography (CT) was performed, revealing tracheal stenosis caused by a tumor in the upper airway...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27621881/modified-bronchial-anastomosis-in-video-assisted-thoracoscopic-sleeve-lobectomy-a-report-of-32-cases
#10
Hao Chen, Lin Huang, Guobing Xu, Bin Zheng, Wei Zheng, Yong Zhu, Zhaohui Guo, Chun Chen
BACKGROUND: Bronchial anastomosis is a key technical challenge in sleeve lobectomy, especially when using the video-assisted thoracoscopic surgery (VATS) approach. A retrospective study was conducted to evaluate the feasibility and safety of a modified bronchial anastomosis technique developed by the authors at Fujian Union Hospital. METHODS: From October 2010 to October 2015, we performed 32 cases of VATS sleeve lobectomy through a three-port or single-port approach...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27594885/tracheobronchial-amyloidosis-mimicking-tracheal-tumor
#11
Elif Tanrıverdi, Mehmet Akif Özgül, Oğuz Uzun, Şule Gül, Mustafa Çörtük, Zehra Yaşar, Murat Acat, Naciye Arda, Erdoğan Çetinkaya
Tracheobronchial amyloidosis is a rare presentation and accounts for about 1% of benign tumors in this area. The diagnosis of disease is delayed due to nonspecific pulmonary symptoms. Therapeutic approaches are required to control progressive pulmonary symptoms for most of the patients. Herein, we report a case of a 68-year-old man admitted with progressive dyspnea to our institution for further evaluation and management. He was initially diagnosed with and underwent management for bronchial asthma for two years but had persistent symptoms despite optimal medical therapy...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27568177/refractory-wheezing-in-chinese-children-under-3%C3%A2-years-of-age-bronchial-inflammation-and-airway-malformation
#12
Wenjing Gu, Wujun Jiang, Xinxing Zhang, Zhengrong Chen, Yongdong Yan, Li Huang, Meijuan Wang, Xuejun Shao, Shuhui Wang, Wei Ji
BACKGROUND: Wheezing is a common symptom in early childhood. However, refractory wheezing is difficult to treat, and it may thus account for extensive use of medical resources. It is therefore important to improve our understanding of the pathophysiology of refractory childhood wheezing. METHODS: In this descriptive study, we studied 156 children with refractory wheezing using fiberoptic bronchoscopy and bronchoalveolar lavage (BAL), and compared the results with a control group of 46 children with various pulmonary diseases but no wheezing...
August 27, 2016: BMC Pediatrics
https://www.readbyqxmd.com/read/27530791/-application-of-electronic-bronchoscopy-in-pediatric-intensive-care-patients-with-difficult-ventilator-weaning
#13
Lu Gong, Lan Hu
OBJECTIVE: To investigate the value of electronic bronchoscopy in the etiological diagnosis and treatment of pediatric intensive care patients with difficult ventilator weaning. METHODS: A retrospective analysis was performed for the clinical data of 92 pediatric intensive care patients with difficult ventilator weaning and underwent electronic bronchoscopy. RESULTS: Among all the 92 children, the most common underlying disease was respiratory system disease (39 children)...
August 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27505140/a-case-of-pulmonary-artery-sling-where-onset-was-induced-by-therapeutic-hypothermia
#14
Junya Nakajima, Daisuke Sunohara, Hisashi Kawashima
A neonate with severe neonatal asphyxia was treated with therapeutic hypothermia. He developed hypothermia-induced respiratory deterioration, after which congenital tracheal stenosis and pulmonary artery sling were diagnosed. Even low-grade hypothermia is likely to induce bronchial narrowing in neonates, especially in neonates with congenital respiratory tract anomalies. Congenital tracheal stenosis represents a potential pitfall in differential diagnosis and should be carefully ruled out in cases of bronchial narrowing episode induced by therapeutic hypothermia...
August 9, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27495017/diagnose-of-occult-bronchial-foreign-body-a-rare-case-report-of-undetected-chinese-medicine-aspiration-for-10-long-years
#15
Lan Wang, Bigyan Pudasaini, Xue-Fen Wang
BACKGROUND: Occult bronchial foreign body can be very difficult to diagnose early in an adult patient without acute symptoms. This report describes a rare case of undetected Chinese medicine "Coptis chinensis" aspiration for 10 long years. METHODS: A case was reported that a female patient complained of a 10-year history of productive cough. A battery of tests were given to confirm the diagnosis. RESULTS: Chest computed tomography (CT) showed extensive bronchiectasis and multiple nodules, along with stenosis of left lower lobar bronchus...
August 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27493804/high-dose-rate-brachytherapy-as-a-treatment-option-in-endobronchial-tumors
#16
Ali Hosni, Andrea Bezjak, Alexandra Rink, Kasia Czarnecka, Andrew McPartlin, Susan Patterson, Elantholiparameswaran Saibishkumar
Purpose. To report our experience with high dose rate endobronchial brachytherapy (HDR-EBBT) and to assess its efficacy and tolerability with possibility of its use in selected cases with curative intent. Method. Retrospective review of patients with endobronchial tumors treated at our institution in 2007-2013 with HDR-EBBT. Subjective response and treatment related toxicity were extracted from patients' records. Clinical response was evaluated by chest CT +/- bronchoscopy 2-3 months after treatment. Local control (LC) and overall survival (OS) were analyzed...
2016: Lung Cancer International
https://www.readbyqxmd.com/read/27449446/a-novel-surgical-technique-for-right-sided-interrupted-aortic-arch-by-interposition-of-a-pulmonary-autograft-tube
#17
Nobuyasu Kato, Masaaki Yamagishi, Takako Miyazaki, Yoshinobu Maeda, Satoshi Asada, Hisayuki Hongu, Eijiro Yamashita, Hitoshi Yaku
Right-sided interrupted aortic arch (IAA) is a rare cardiac anomaly. In general, the right bronchus sits higher than the left bronchus, so aortic arch reconstruction with a direct anastomosis has a risk of tracheal and bronchial obstruction. This report describes the successful definitive repair of a right-sided IAA in a 2.5-kg neonate by aortic arch reconstruction with a pulmonary autograft tube (PA tube). Postoperative three-dimensional multidetector computed tomography showed the reconstructed aortic arch without airway obstruction or aortic stenosis...
August 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27424828/biphasic-flow-volume-loop-in-granulomatosis-with-polyangiitis-related-unilateral-bronchus-obstruction
#18
Abhinav Agrawal, Sonu Sahni, Galina Marder, Rakesh Shah, Arunabh Talwar
Spirometry flow-volume measurement is used routinely in the outpatient setting to rule out obstructive lung diseases. Biphasic flow-volume loop is a classic presentation of unilateral bronchial stenosis due to multiple etiologies and it should raise clinical suspicion. Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition with pulmonary manifestations that may be infiltrative (e.g., pneumonia), hemorrhagic, and may rarely cause bronchial stenosis. Herein, we present a case of GPA-related, bronchial obstruction that caused biphasic flow-volume loop along with a literature review...
July 2016: Respiratory Investigation
https://www.readbyqxmd.com/read/27272782/the-difference-in-bronchial-patency-between-the-sweet-and-modified-overfolt-methods-at-a-deep-site-current-strategies-are-based-on-previous-knowledge
#19
Yuki Nakajima, Yoshihito Iijima, Hidetaka Uramoto
The use of bronchial stapling with automatic stapling devices has become widespread in chest surgery with the growth of video-assisted thoracoscopic surgery. Thus, hand suturing for the bronchus occurs less commonly. Therefore, modern surgeons have fewer opportunities to perform hand suturing, and, as a consequence, there exists lack understanding of this technique compared to earlier generations. We, therefore, examined the difference in bronchial patency between the Sweet and modified Overfolt methods of suturing performed on sacrificed pigs, as shown by bronchoscopy...
June 2016: Anticancer Research
https://www.readbyqxmd.com/read/27272691/the-concept-of-the-arch-window-in-the-spiral-switch-of-the-great-arteries
#20
Ing-Sh Chiu, Meng-Luen Lee, Shu-Chien Huang, Chung-I Chang, Yih-Sharng Chen, Mei-Hwan Wu, Robert H Anderson
When the arterial switch operation includes the Lecompte maneuver, the arterial trunks are reconnected in parallel, rather than the spiral fashion observed in the normal heart. Thus, although the ventriculo-arterial connections are hemodynamically corrected, the anatomic arrangement cannot be considered normal. We hypothesized that, if feasible, it would be advantageous to restore a spiral configuration for the arterial trunks. In 58 patients, we reconstructed the arterial trunks such that, postoperatively, the pulmonary channel spirals round the aorta, passing to either the right or the left, and branches posteriorly...
August 2016: Pediatric Cardiology
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