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Endobronchial tumor debulking

Scott Chih-Hsi Kuo, Yu-Lun Lo, Chun-Liang Chou, Fu-Tsai Chung, Shu-Min Lin, Chien-Ying Liu, Han-Pin Kuo
BACKGROUND: Central airway obstruction related to endobronchial malignancy is one of the most difficult oncological complications and requires efficient palliative intervention. METHODS: Fifty-three consecutive patients with unresectable endobronchial malignancy receiving bronchoscopic cryotherapy as palliative treatment were retrospectively reviewed. Efficiency was evaluated by the improvement of performance status (PS), and the best achievement of tumor removal was assessed as complete or partial removal...
November 2015: Thoracic Cancer
Rade Tomic, Eitan Podgaetz, Rafael S Andrade, H Erhan Dincer
Cryotechnology has been used in treating lung cancer for many years, now it is emerging to have a new indication in diagnosing lung diseases. Cryoprobe transbronchial lung biopsy has been introduced into clinical practice as a new technique, providing a larger biopsy specimen, potentially improving the diagnostic yield of transbronchial biopsies in parenchymal lung diseases. Although recent small pilot studies suggest that cryotransbronchial lung biopsies are comparable to conventional transbronchial biopsies in terms of diagnostic yield and safety profile in lung transplant patients, cryoprobe transbronchial lung biopsy is still being evaluated and its role in clinical practice is not well defined...
January 2015: Journal of Bronchology & Interventional Pulmonology
Muhammad R S Rashid Ali, Kunji K S Kannan
We report a case of a 52-year-old patient who had undergone a bladder resection and an ileal conduit for a transitional cell carcinoma. He then presented with a short history of hemoptysis 3 months later. Rigid bronchoscopy was performed revealing an endobronchial lesion, which was removed via laser and debulking method without complications. Histopathologic examination confirmed it to be a benign endobronchial glomus tumor. On the basis of our literature search, this is the 34th reported case of glomus tumor arising from the respiratory tract, seventh reported case of an endobronchial glomus tumor treated bronchoscopically, and the first possibly coincidental finding in relation to a patient with primary transitional bladder cell carcinoma...
January 2015: Journal of Bronchology & Interventional Pulmonology
Andreas Espinoza, Kirill Neumann, Per Steinar Halvorsen, Arve Sundset, Johny Kongerud, Erik Fosse
BACKGROUND: Endobronchial interventions are used to alleviate symptoms of airway stenosis. The ventilatory management may be challenging during these procedures, and may influence the choice of airway device. We report our experiences from 902 procedures. METHODS: Patients undergoing interventional bronchoscopy procedures were consecutively registered from 1999 to 2012. Critical airway obstruction (CAO) was defined as stridor, tracheal diameter <5 mm, stenosis of both the main bronchi, or clots/tumor fragments occluding the trachea or both main bronchi...
January 2015: Journal of Bronchology & Interventional Pulmonology
Alfred Papali, Ashutosh Sachdeva, Edward Pickering, Nirav Shah
SESSION TITLE: Bronchology/Interventional Global Case ReportsSESSION TYPE: Global Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Kaposi sarcoma (KS) remains the most common AIDS-associated neoplasm. Endobronchial KS typically appears as slightly raised, violaceous lesions in the sub-mucosa of the endobronchial wall and is usually associated with similar mucocutaneous lesions elsewhere on the body. We herein describe an unusual case of KS presenting as an isolated obstructing endobronchial tumor that was effectively resected using electrocautery snare and argon plasma coagulation (APC)...
October 1, 2014: Chest
Shinichi Iwamoto, Hibiki Kanda, Mitsuhiro Tada, Emiko Nishikawa, Toru Kadowaki, Masahiro Kimura, Kanako Kobayashi, Toshikazu Ikeda, Shuichi Yano
Bronchology/Interventional Global Case ReportsSESSION TYPE: Global Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Bronchial ethanol injection therapy is a palliative therapy for air way stenosis caused by lung cancer. It is effective for endobronchial polypoid tumors but ineffective for extrawall tumors. There were no indication of effects resulting from ethanol injection or air way leakage of ethanol. We performed an initial study to examine the ability of endobronchial ultrasound-guided bronchial ethanol injection therapy (EBUS-BEIT) to reduce the blood flow and volume of an endobronchial tumor causing tracheal stenosis; percutaneous ethanol injection therapy (PEIT) was also performed for a liver cell tumor and a parathyroid tumor...
October 1, 2014: Chest
Tanmay Panchabhai, Debabrata Bandyopadhyay, Siva Raja, Sudhish Murthy, Vamsidhar Velcheti, Sanjay Mukhopadhyay, Joseph Cicenia, Sonali Sethi
Bronchology/Interventional Procedures Cases IISESSION TYPE: Affiliate Case Report SlidePRESENTED ON: Monday, October 27, 2014 at 11:00 AM - 12:00 PMINTRODUCTION: Inflammatory Myofibroblastic tumors (IMT) were previously included in the loose term "Inflammatory Pseudotumor." However, the rarity of these tumors makes diagnosis and management fairly challenging. We present an interesting presentation of an endobronchial presentation of IMT.CASE PRESENTATION: An 18-year-old non-smoking female presented with cough and intermittent hemoptysis over a few weeks...
October 1, 2014: Chest
Zhou Zhang, Vincent Chan, Luis Moreta-Sainz
Cancer Student/Resident Case Report Posters IISESSION TYPE: Medical Student/Resident Case ReportPRESENTED ON: Tuesday, October 28, 2014 at 01:30 PM - 02:30 PMINTRODUCTION: Endobronchial leiomyoma is a rare benign tumor of the lung. We describe an adult male found to have endobronchial leiomyoma presenting with chronic cough.CASE PRESENTATION: A 54 year-old male from the Philippines presented with 6 months of persistent cough following antibiotic treatment for right lower lobe pneumonia. Due to persistent symptoms and a 10 pack-year smoking history, a chest CT was performed to rule out malignancy, revealing a right lower lobe endobronchial lesion...
October 1, 2014: Chest
Chan Woo Park, Woojin Kim, In Jae Oh, Kyu Sik Kim, Yoo Duk Choi, Yong Soo Kwon
Solitary extramedullary plasmacytoma (SEP) is a plasma cell neoplasm that develops outside of the bone marrow. A solitary, exophytic growth in the airway is an extremely rare presentation of SEP. We herein report a case of SEP presenting as an endobronchial mass. The tumor was treated by rigid bronchoscopic debulking followed by ablation using argon plasma coagulation. However, the tumor could not be completely removed due to its wide base. Adjuvant radiotherapy was administered as the curative therapy. A biopsy was performed on the resected specimen and the diagnosis of plasmacytoma was thereby confirmed...
2013: Internal Medicine
J Hetzel, M Böckeler
Malignant central airway obstruction is a common problem in lung cancer. A symptomatic stenosis can often be treated successfully using endoscopy. Different approaches for recanalisation are available. The goal of treating exophytic obstruction is to remove the endobronchial tumour growth. Mechanic debulking, electrocautery/diathermy, argon plasma coagulation, laser resection and cryoextraction are techniques that can provide immediate relief. Cryotherapy, brachytherapy and photodynamic therapy show delayed recanalisation effects...
July 2012: Pneumologie
K Khodadad, S Karimi, M Arab, Z Esfahani-Monfared
Primary anaplastic large cell lymphoma of the trachea is a rare tumor. Common complaints are dyspnea and cough that could mimic a partially refractory asthma in some cases. We report a 16-year-old female with an anaplastic large cell lymphoma (null cell type) in which tracheal involvement was presented with life-threatening airway obstruction and subcutaneous emphysema. After debulking the tumor by endobronchial curettage, the patient was treated with chemotherapy followed by local radiotherapy. She had no evidence of local or distant recurrence after 25 months...
2011: Hematology/oncology and Stem Cell Therapy
Armin Ernst, Devanand Anantham
Interventional bronchoscopy, together with other domains of interventional pulmonology, has experienced tremendous technological advances. Diagnostic applications include endobronchial ultrasound, which enables endoscopists to see through airway walls. White light videobronchoscopy, autofluorescence imaging, and narrow band imaging have enhanced the ability to detect early lung cancer at a preinvasive stage. Electromagnetic navigational bronchoscopy, ultrathin bronchoscopy, and virtual bronchoscopy increase the diagnostic yield of biopsy of small peripheral lung lesions...
November 2011: Journal of Thoracic Imaging
Ali Saeed Wahla, Irtaza Khan, Christina Bellinger, Edward Haponik, John Frank Conforti
AIMS: Pulmonary leiomyomas are rare benign tumors that may cause symptoms when they spread endobronchially. Traditionally they were managed surgically or through interventional bronchoscopy with the aid of thermal modalities to assist in debulking of tumor. We report the novel use of microdebrider bronchoscopy to debulk an endobronchial leiomyoma in a symptomatic patient. METHOD/RESULTS: The microdebrider successfully débrided the endobronchial leiomyoma. CONCLUSION: This modality can be successfully employed when oxygenation is an issue, preventing use of thermal modalities...
April 2011: Clinical Respiratory Journal
Patricia A Thistlethwaite, John Renner, David Duhamel, Samir Makani, Grace Y Lin, Stuart W Jamieson, James Harrell
BACKGROUND: Endobronchial myofibroblastic tumors are neoplasms composed of clonal populations of smooth muscle cells and a variable lymphocytic inflammatory component. They represent a challenge with respect to diagnosis, classification, and surgical resection due to their infrequent occurrence. METHODS: We retrospectively reviewed our experience with patients who had myofibroblastic tumors in the major airways over a 15-year period, in order to understand the incidence, natural biology, treatment, and long-term outcome of individuals with this type of neoplasm in an endobronchial location...
February 2011: Annals of Thoracic Surgery
M J Gonçalves, M M Mendes, F João, J M Lopes, M Honavar
Primary sarcomas of the lung are uncommon, potentially aggressive neoplasms that need to be distinguished from other malignant pulmonary tumors and whose biological behavior is as yet not fully understood. Primary undifferentiated pleomorphic sarcoma was diagnosed in the right lung of a 66 year-old man, who has survived over 11 years after treatment with endobronchial tumor debulking by laser therapy and radiotherapy.
January 2011: Revista Portuguesa de Pneumologia
Hongwu Wang, Yunzhi Zhou, Heng Zou, Jing Li
BACKGROUND: Main airway severe obstruction is a problem facing difficulty flexible bronchoscope because the patient is not able to breath smoothly under prostration, and death from suffocation is a frequent outcome. Managing the airway of patients with critical tracheal stenosis remains a formidable challenge to bronchoscopists. This study is to evaluate the application and efficacy of argon plasma coagulation (APC) and cryoextraction for the treatment of endobronchial neoplasma under rigid bronchoscope combined with flexible bronchoscope...
February 20, 2009: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
Basem Abdelmalak, Nicholas Marcanthony, Joseph Abdelmalak, Michael S Machuzak, Thomas R Gildea, D John Doyle
Anesthetic management of anterior mediastinal masses (AMM) is challenging. We describe the successful anesthetic management of two patients with AMM in which dexmedetomidine was used at supra-sedative doses. Our first case was a 41-year-old man who presented with a 10 x 9 x 11 cm AMM, a pericardial effusion, compression of the right atrium, and superior vena cava syndrome. He had severe obstruction of the right mainstem bronchus, distal trachea with tumor compression, and endobronchial tumor invasion. Our second case was a 62-year-old man with tracheal and bronchial obstruction secondary to a recurrent non-small-cell lung cancer mediastinal mass...
August 2010: Journal of Anesthesia
Christian Schumann, Martin Hetzel, Alexander J Babiak, Jürgen Hetzel, Tobias Merk, Thomas Wibmer, Philipp M Lepper, Stefan Krüger
OBJECTIVE: In addition to use of a laser, argon plasma coagulation, electrocautery, or coring with a rigid bronchoscope, tumor debulking with a flexible cryoprobe is used for therapeutic bronchoscopy with an immediate effect for endobronchial pathologies. We performed this analysis to determine the usefulness, efficacy, and safety of the flexible cryorecanalization in a large population under routine conditions. METHODS: We identified 225 bronchoscopic interventions that were done as cryorecanalization with a flexible cryoprobe...
April 2010: Journal of Thoracic and Cardiovascular Surgery
Daniel T DeArmond, Ali Mahtabifard, Clark B Fuller, Robert J McKenna
Photodynamic therapy is an effective technique for debulking endobronchial tumors over an acceptably short time-course; however, to be effective, numerous treatment cycles may be required to achieve the desired results. We present a case in which photodynamic therapy was used with curative intent to downsize an obstructing endobronchial non-small cell lung cancer in advance of resection via video-assisted thoracoscopic surgery with right upper lobe sleeve lobectomy.
May 2008: Annals of Thoracic Surgery
A H Nassiri, H Dutau, D Breen, A Colchen, J J Quiot, B Nguyen, J M Vergnon et al.
BACKGROUND: Pulmonary lipomas are rare benign tumors that are usually found endobronchially. Undiagnosed, they can lead to the serious late sequelae associated with endobronchial obstruction. In the majority of cases, they are located in the first three subdivisions of the tracheobronchial tree, and therefore, they are amenable to endoscopic techniques for diagnostic and therapeutic purposes. OBJECTIVES: It was our aim to retrospectively study the bronchoscopic management and follow-up of a large series of endobronchial lipomas, as well as defining the demographic and endoscopic characteristics of patients...
2008: Respiration; International Review of Thoracic Diseases
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