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https://www.readbyqxmd.com/read/29161670/construction-of-plasmonic-ag-modified-phosphorous-doped-ultrathin-g-c3n4-nanosheets-bivo4-photocatalyst-with-enhanced-visible-near-infrared-response-ability-for-ciprofloxacin-degradation
#1
Yaocheng Deng, Lin Tang, Chengyang Feng, Guangming Zeng, Jiajia Wang, Yaoyu Zhou, Yani Liu, Bo Peng, Haopeng Feng
To realize the full utilization of solar energy, the design of highly efficient photocatalyst with improved visible-near-infrared photocatalysis performance has attracted great attentions for environment pollutant removal. In this work, we rationally employed the surface plasmon resonance effect of metallic Ag in the phosphorus doped ultrathin g-C3N4 nanosheets (PCNS) and BiVO4 composites to construct a ternary Ag@PCNS/BiVO4 photocatalyst. It was applied for the photodegradation of ciprofloxacin (CIP), exhibiting 92...
November 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29161650/how-the-morphological-properties-of-mentha-longifolia-l-huds-may-be-affected-by-geographical-differences
#2
Mohammad Mohammadi, Hossein Ali Asadi-Gharneh
With respect to the benefits of medicinal plants for human health and their use as food, they are extensively being researched and planted in different parts of the world including Iran. Among the most important parameters, which may affect the growth and the yield of medicinal plants is their geographical (ecotype) properties. Accordingly, a research work was proposed to investigate the effects of 10 different regions or ecotypes on the morphological properties of pennyroyal [Mentha longifolia. (L.) Huds.] from the Lamiaceae family in one of the Iranian provinces, namely Ilam...
October 28, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29161568/feasibility-of-high-concentration-cellulosic-bioethanol-production-from-undetoxified-whole-monterey-pine-slurry
#3
Chengyu Dong, Ying Wang, Han Zhang, Shao-Yuan Leu
The economic feasibility of high-concentration cellulosic bioethanol production remains challenging because it requires easily available feedstock and low energy consumption process. Simultaneous saccharification and fermentation (SSF) of sulfite pretreated Momentary pine slurry at 20% (w/w) loadings increased ethanol concentration from 59.3 g/L to 68.5 g/L by washing strategy. Effects of inhibitors in pretreatment liquor were further investigated. Besides HMF, furfural and acetic acid, other inhibitors and/or their synergistic effects proved to be responsible for a lower fermentability...
November 11, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/29161434/designing-a-mutant-candida-uricase-with-improved-polymerization-state-and-enzymatic-activity
#4
Lei Tao, Dandan Li, Yonghong Li, Xinchang Shi, Junzhi Wang, Chunming Rao, Yingqi Zhang
As human uricase has been silenced during evolution, counterparts from other species become an alternative for the treatment of hyperuricemia. Candida uricase is a promising option among them, but its aggregation propensity remains a major obstacle to clinical use. In this study, we designed two mutations according to homology-modeled 3D structure of Candida uricase: Cys249Ser substitution and C-terminal Leu deletion. The wild-type uricase and three mutants containing either or both of the mutations were expressed in Escherichiacoli BL21 and validated by mass spectrometry...
November 17, 2017: Protein Engineering, Design & Selection: PEDS
https://www.readbyqxmd.com/read/29161317/evaluating-architecture-impact-on-system-energy-efficiency
#5
Shijie Yu, Hailong Yang, Rui Wang, Zhongzhi Luan, Depei Qian
As the energy consumption has been surging in an unsustainable way, it is important to understand the impact of existing architecture designs from energy efficiency perspective, which is especially valuable for High Performance Computing (HPC) and datacenter environment hosting tens of thousands of servers. One obstacle hindering the advance of comprehensive evaluation on energy efficiency is the deficient power measuring approach. Most of the energy study relies on either external power meters or power models, both of these two methods contain intrinsic drawbacks in their practical adoption and measuring accuracy...
2017: PloS One
https://www.readbyqxmd.com/read/29161301/detection-and-quantification-of-dengue-virus-using-a-novel-biosensor-system-based-on-dengue-ns3-protease-activity
#6
Ming-Shu Hsieh, Mei-Yu Chen, Chun-Hsiang Hsieh, Chien-Hsiung Pan, Guann-Yi Yu, Hsin-Wei Chen
BACKGROUND: The traditional methods, plaque assays and immuno-focus assays, used to titrate infectious dengue virus (DENV) particles are time consuming and labor intensive. Here, we developed a DENV protease activity detection system (DENPADS) to visualize DENV infection in cells based on dengue protease activity. METHODOLOGY/PRINCIPAL FINDINGS: Dengue NS3 protease cleaves NS4B-NS5. BHK-21 cells stably expressing the sensor module comprising DENV-2 NS4 and the 10 amino-terminal amino acids of NS5 (N10NS5) fused with the SV40 nuclear localization signal (NLS) and Cre recombinase (Cre), were generated...
2017: PloS One
https://www.readbyqxmd.com/read/29161271/a-mathematical-function-for-the-description-of-nutrient-response-curve
#7
Hamed Ahmadi
Several mathematical equations have been proposed to modeling nutrient-response curve for animal and human justified on the goodness of fit and/or on the biological mechanism. In this paper, a functional form of a generalized quantitative model based on Rayleigh distribution principle for description of nutrient-response phenomena is derived. The three parameters governing the curve a) has biological interpretation, b) may be used to calculate reliable estimates of nutrient response relationships, and c) provide the basis for deriving relationships between nutrient and physiological responses...
2017: PloS One
https://www.readbyqxmd.com/read/29161252/choose-rate-or-squeeze-comparison-of-economic-value-functions-elicited-by-different-behavioral-tasks
#8
Alizée Lopez-Persem, Lionel Rigoux, Sacha Bourgeois-Gironde, Jean Daunizeau, Mathias Pessiglione
A standard view in neuroeconomics is that to make a choice, an agent first assigns subjective values to available options, and then compares them to select the best. In choice tasks, these cardinal values are typically inferred from the preference expressed by subjects between options presented in pairs. Alternatively, cardinal values can be directly elicited by asking subjects to place a cursor on an analog scale (rating task) or to exert a force on a power grip (effort task). These tasks can vary in many respects: they can notably be more or less costly and consequential...
November 21, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29161038/a-ag-catalyzed-tandem-three-component-reaction-towards-the-synthesis-of-multisubstituted-imidazoles
#9
Changcheng Wang, Jialin Lai, Cantao Chen, Xuechen Li, Hua Cao
A facile one pot, Ag-catalyzed tandem three-component reaction of amidines, ynals, and carboxylic acids or amines to form imidazole skeletons has been developed. This multicomponent reaction has been applied to various substituted amidines and carboxylic acids substrates, affording the products in good yields. The strategy could provide an efficient and green molecular fragment assembly to access imidazoles.
November 21, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/29161009/a-sensitive-microbead-based-organic-media-assisted-method-for-proteomics-sample-preparation-from-dilute-and-denaturing-solutions
#10
Masato Taoka, Michihiko Fujii, Masahiro Tsuchiya, Takamasa Uekita, Tohru Ichimura
We developed a robust and sensitive sample preparation method for proteomics termed microbead-based and organic-media-assisted proteolysis strategy (BOPs). BOPs combine two advantages of current techniques, (1) unbiased binding of reversed-phase polymeric microbeads to any type of protein and (2) enhanced trypsin digestion efficiency in CH3CN-aqueous solvent systems, into a single-tube workflow. Compared with conventional techniques, this method effectively concentrates proteins and improves proteolytic digestion, and can be used with submicromolar protein samples in dilute and/or denaturing solutions such as 70 % formic acid, 8 M urea, or 7 M guanidine hydrochloride without any sample pretreatment...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29160846/a-triphenylphosphonium-functionalized-mitochondriotropic-nanocarrier-for-efficient-co-delivery-of-doxorubicin-and-chloroquine-and-enhanced-antineoplastic-activity
#11
Katerina N Panagiotaki, Zili Sideratou, Spiros A Vlahopoulos, Maria Paravatou-Petsotas, Michael Zachariadis, Nikolas Khoury, Vassilis Zoumpourlis, Dimitris Tsiourvas
Drug delivery systems that target subcellular organelles and, in particular, mitochondria are considered to have great potential in treating disorders that are associated with mitochondrial dysfunction, including cancer or neurodegenerative diseases. To this end, a novel hyperbranched mitochondriotropic nanocarrier was developed for the efficient co-delivery of two different (both in chemical and pharmacological terms) bioactive compounds. The carrier is based on hyperbranched poly(ethyleneimine) functionalized with triphenylphosphonium groups that forms ~100 nm diameter nanoparticles in aqueous media and can encapsulate doxorubicin (DOX), a well-known anti-cancer drug, and chloroquine (CQ), a known chemosensitizer with arising potential in anticancer medication...
November 21, 2017: Pharmaceuticals
https://www.readbyqxmd.com/read/29160845/vascular-endothelial-growth-factor-sequestration-enhances-in-vivo-cartilage-formation
#12
Carolina M Medeiros Da Cunha, Valeria Perugini, Petra Bernegger, Matteo Centola, Andrea Barbero, Anna L Guildford, Matteo Santin, Andrea Banfi, Ivan Martin, Anna Marsano
Autologous chondrocyte transplantation for cartilage repair still has unsatisfactory clinical outcomes because of inter-donor variability and poor cartilage quality formation. Re-differentiation of monolayer-expanded human chondrocytes is not easy in the absence of potent morphogens. The Vascular Endothelial Growth Factor (VEGF) plays a master role in angiogenesis and in negatively regulating cartilage growth by stimulating vascular invasion and ossification. Therefore, we hypothesized that its sole microenvironmental blockade by either VEGF sequestration by soluble VEGF receptor-2 (Flk-1) or by antiangiogenic hyperbranched peptides could improve chondrogenesis of expanded human nasal chondrocytes (NC) freshly seeded on collagen scaffolds...
November 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29160822/how-secondary-and-tertiary-amide-moieties-are-molecular-stations-for-dibenzo-24-crown-8-in-2-rotaxane-molecular-shuttles
#13
Benjamin Riss-Yaw, Justine Morin, Caroline Clavel, Frédéric Coutrot
Interlocked molecular machines like [2]rotaxanes are intriguing aesthetic molecules. The control of the localization of the macrocycle, which surrounds a molecular axle, along the thread leads to translational isomers of very different properties. Although many moieties have been used as sites of interactions for crown ethers, the very straightforwardly obtained amide motif has more rarely been envisaged as molecular station. In this article, we report the use of secondary and tertiary amide moieties as efficient secondary molecular station in pH-sensitive molecular shuttles...
November 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29160715/deciphering-charging-status-absolute-quantum-efficiency-and-absorption-cross-section-of-multi-carrier-states-in-single-colloidal-quantum-dot
#14
Weiwang Xu, Xiaoqi Hou, Yongjun Meng, Renyang Meng, Zhiyuan Wang, Haiyan Qin, Xiaogang Peng, Xue-Wen Chen
Upon photo- or electrical-excitation, colloidal quantum dots (QDs) are often found in multi-carrier states due to multi-photon absorption and photo-charging of the QDs. While many of these multi-carrier states are observed in single-dot spectroscopy, their properties are not well studied due to random charging/discharging, emission intensity intermittency, and uncontrolled surface defects of single QD. Here we report in-situ deciphering the charging status, and precisely assessing the absorption cross section, and determining the absolute emission quantum yield of mono-exciton and biexciton states for neutral, positively-charged, and negatively-charged single core/shell CdSe/CdS QD...
November 21, 2017: Nano Letters
https://www.readbyqxmd.com/read/29160704/nanobiotechnology-for-environment-innovative-solutions-for-the-management-of-harmful-algal-blooms
#15
Matthew Robert Gellert, Beum Jun Kim, Samuel Evan Reffsin, Sebastian Eureko Jusuf, Nicole Denise Wagner, Stephen Winans, Mingming Wu
Nanobiotechnology has played important roles in solving contemporary health problems including cancer and diabetes, but has not yet been widely exploited for problems in food security and environmental protection. Water scarcity is an emerging worldwide problem due to climate change and population increase. Current methods of managing water resources are not efficient or sustainable. In this perspective, we focus on harmful algal blooms to demonstrate how nanobiotechnology can be explored to understand microbe-environment interaction and allow for toxin/pollutant detection with significantly improved sensitivity...
November 21, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29160685/graphene-oxide-a-new-carrier-for-slow-release-of-plant-micronutrients
#16
Shervin Kabiri, Fien Degryse, Diana N H Tran, Rodrigo da Silva, Michael J McLaughlin, Dusan Losic
The environmental problems and low efficiency associated with conventional fertilizers provides an impetus to develop advanced fertilizers with slower release and better performances. Here we report of development of a new carrier platform based on graphene oxide (GO) sheets that can provide a high loading of plant micronutrients with controllable slow release. To prove this concept two micronutrients zinc (Zn) and copper (Cu) were used to load on GO sheets and hence formulate GO-based micronutrients fertilizer...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29160619/tendinopathy-diagnosis-and-treatment-monitoring-using-attenuated-total-reflectance-fourier-transform-infrared-spectroscopy
#17
Tanmoy T Bhattacharjee, Mariana C Nicodemo, Luciana B Sant'Anna, Emilia A Lo Schiavo Arisawa, Leandro Raniero
Tendinopathy, an important sports injury afflicting athletes and general public, is associated with huge economic losses. The currently used diagnostic tests are subjective, show moderate sensitivity and specificity; while treatment failures persist despite advances in therapy. This highlights the need for tendinopathy diagnostic and treatment monitoring tools. The current study investigates tendon injury, natural healing and effect of treatment using ATR-FTIR complemented with histopathology. Control (C), injured (I) and treated (T) rat tendons were extracted 3, 7, 14 and 28 days post injury/treatment, representing phases of healing; and subjected to H&E staining as well as spectroscopy...
November 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/29160609/plant-arthropod-interactions-who-is-the-winner
#18
Elia Stahl, Olivier Hilfiker, Philippe Reymond
Herbivorous arthropods have interacted with plants for millions of years. During feeding they release chemical cues that allow plants to detect the attack and mount an efficient defense response. A signaling cascade triggers the expression of hundreds of genes, which encode defensive proteins and enzymes for synthesis of toxic metabolites. This direct defense is often complemented by emission of volatiles that attract beneficial parasitoids. In return, arthropods have evolved strategies to interfere with plant defenses, either by producing effectors to inhibit detection and downstream signaling steps, or by adapting to their detrimental effect...
November 21, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29160592/sugar-flux-and-signaling-in-plant-microbe-interactions
#19
Margaret Bezrutczyk, Jungil Yang, Joon-Seob Eom, Matthew Prior, Davide Sosso, Thomas Hartwig, Boris Szurek, Ricardo Oliva, Casiana Vera-Cruz, Frank F White, Bing Yang, Wolf B Frommer
Plant breeders have developed crop plants that are resistant to pests, but the continual evolution of pathogens creates the need to iteratively develop new control strategies. Molecular tools have allowed us to gain deep insights into disease responses, allowing for more efficient, rational engineering of crops that are more robust or resistant to a greater number of pathogen variants. Here we describe the roles in disease progress of SWEET and STP transporters, which are membrane proteins that mediate transport of sugars across the plasma membrane...
November 21, 2017: Plant Journal: for Cell and Molecular Biology
https://www.readbyqxmd.com/read/29160437/access-and-adherence-to-medication-among-people-with-diabetes-in-brazil-evidences-from-pnaum
#20
Micheline Marie Milward de Azevedo Meiners, Noemia Urruth Leão Tavares, Luciano Santos Pinto Guimarães, Andréa Dâmaso Bertoldi, Tatiane da Silva Dal Pizzol, Vera Lucia Luiza, Sotero Serrate Mengue, Edgar Merchan-Hamann
OBJECTIVE: To describe people with diabetes in Brazil and to compare their sociodemographic characteristics, access and self-reported adherence to diabetes prescribed drugs. METHODS: Data analysis from the National Survey on Access, Use and Promotion of the Rational Use of Medicines, a household survey, with sampling by clusters, according to sex and age domains and national and macro-regional representativeness. Adults (≥ 20 years old) who reported having diabetes constituted the sample...
July 2017: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
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