Toufik Abdul-Rahman, Wireko Andrew Awuah, Tatiana Mikhailova, Jacob Kalmanovich, Aashna Mehta, Jyi Cheng Ng, Megan Ariel Coghlan, Marija Zivcevska, Alexander J Tedeschi, Emerson Costa de Oliveira, Akinchita Kumar, Emiliano Cantu-Herrera, Mykola Lyndin, Kateryna Sikora, Athanasios Alexiou, Anwar L Bilgrami, Khalid Mohammed Al-Ghamdi, Asma Perveen, Marios Papadakis, Ghulam Md Ashraf
Alzheimer's disease (AD) constitutes a multifactorial neurodegenerative pathology characterized by cognitive deterioration, personality alterations, and behavioral shifts. The ongoing brain impairment process poses significant challenges for therapeutic interventions due to activating multiple neurotoxic pathways. Current pharmacological interventions have shown limited efficacy and are associated with significant side effects. Approaches focusing on the early interference with disease pathways, before activation of broad neurotoxic processes, could be promising to slow down symptomatic progression of the disease...
January 16, 2024: BioFactors