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https://www.readbyqxmd.com/read/28917867/nanocrystalline-cellulose-isolated-from-discarded-cigarette-filters
#1
Segun A Ogundare, Vashen Moodley, Werner E van Zyl
We report the isolation of nanocrystalline cellulose (NCC) produced from discarded cigarette filters (DCF). The DCF were processed into cellulose via ethanolic extraction, hypochlorite bleaching, alkaline deacetylation, and then converted into NCC by sulfuric acid hydrolysis. The morphological structures of the isolated NCC established with TEM showed that the nanocrystals were needle-like with a mean length of 143nm. FEGSEM showed the morphological transition of the micro-sized DCF to self-assembled NCC while EDX revealed the presence of Ti (as TiO2) in DCF, which was retained in the NCC...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917706/the-effects-of-needle-damage-on-annulus-fibrosus-micromechanics
#2
Claudio Vergari, Jessica C Mansfield, Daniel Chan, Andrew Clarke, Judith R Meakin, Peter C Winlove
Needle puncture of the intervertebral disc can initiate a mechanical and biochemical cascade leading to disc degeneration. Puncture's mechanical effects have been shown near the puncture site, mechanical effects should be observed far, relative to needle size, from the puncture site, given the disc-wide damage induced by the stab. The aim of this work was to quantify these far-field effects, and to observe the local structural damage provoked by the needle. Strips of cow tail annulus fibrosus underwent two consecutive mechanical loadings to 5% tensile strain; fifteen samples were punctured in a radial direction with a randomly assigned needle between the two loadings (needle gauges between 19 and 23)...
September 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28910711/a-novel-micro-to-macro-structural-approach-for-mechanical-characterization-of-adipose-tissue-extracellular-matrix
#3
Behzad Seyfi, Nasser Fatouraee, Abbas Samani
Mechanical characterization of adipose tissue micro-components is important for various biomedical applications such as tissue engineering and predicting adipose tissue response to forces involved in relevant medical intervention procedures (e.g. breast needle biopsy). For this characterization, we introduce a novel structural method for micromechanical modeling of the adipose tissue. The micromechanical model was developed using fluid-structure interaction (FSI) formulation. We utilized this model within an inverse problem framework to estimate the hyperelastic parameters of adipose tissue extracellular matrix (ECM)...
September 5, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28904650/dermatologic-microsutures-using-human-hair-a-useful-technique-in-cutaneous-stitching
#4
Mohammed Al Azrak, Rei Ogawa
Background: Facial wounds are challenging for dermatologic surgeons, particularly traumatic facial wounds, because they can yield disfiguring scars. To obtain good results, narrow needles and sutures are needed. Hair filaments have a very small diameter (0.06-0.1 mm) and could serve as suture threads for facial wounds. Objective: To determine the aesthetic outcomes by using autologous hair to suture facial wounds. Patients and Methods: This case series study examined the aesthetic outcomes of all consecutive female patients with traumatic facial wounds who underwent autologous hair-based stitching in 2009-2016...
2017: Eplasty
https://www.readbyqxmd.com/read/28900134/minimally-invasive-micro-indentation-mapping-tissue-mechanics-at-the-tip-of-an-18g-needle
#5
Steven V Beekmans, Kaj S Emanuel, Theodoor H Smit, Davide Iannuzzi
Experiments regarding the mechanical properties of soft tissues mostly rely on data collected on specimens that are extracted from their native environment. During the extraction and in the time period between the extraction and the completion of the measurements, however, the specimen may undergo structural changes which could generate unwanted artifacts. To further investigate the role of mechanics in physiology and possibly use it in clinical practices, it is thus of paramount importance to develop instruments that could measure the viscoelastic response of a tissue without necessarily excising it...
September 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28888788/experimental-and-modelling-characterisation-of-adjustable-hollow-micro-needle-delivery-systems
#6
Ting-Ting Liu, Kai Chen, Min Pan
BACKGROUND: Hollow micro-needles have been used increasingly less in practice because the infusion into the skin is limited by the tissue resistance to flow. The relationship between the infusion flow rate and tissue resistance pressure is not clear. METHODS: A custom-made, hollow micro-needle system was used in this study. The driving force and infusion flow rate were measured using a force transducer attached to an infusion pump. Evans blue dye was injected into the air, polyacrylamide gel and in-vivo mouse skin at different flow rates...
September 6, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28855950/sea-urchin-growth-dynamics-at-microstructural-length-scale-revealed-by-mn-labeling-and-cathodoluminescence-imaging
#7
Przemysław Gorzelak, Aurélie Dery, Philippe Dubois, Jarosław Stolarski
BACKGROUND: Fluorochrome staining is among the most widely used techniques to study growth dynamics of echinoderms. However, it fails to detect fine-scale increments because produced marks are commonly diffusely distributed within the skeleton. In this paper we investigated the potential of trace element (manganese) labeling and subsequent cathodoluminescence (CL) imaging in fine-scale growth studies of echinoderms. RESULTS: Three species of sea urchins (Paracentrotus lividus, Echinometra sp...
2017: Frontiers in Zoology
https://www.readbyqxmd.com/read/28829602/in-situ-characterization-of-oil-in-water-emulsions-stabilized-by-surfactant-and-salt-using-microsensors
#8
Jared Church, Danielle M Paynter, Woo Hyoung Lee
Chemically stabilized emulsions are difficult to break because of micelle stability. Many physical and chemical processes have been used for emulsion breaking/separation; however, most operational parameters are based on empirical data and bulk analysis. A multiscale understanding of emulsions is required before these processes can advance further. This study utilized needle-type microsensors and confocal laser scanning microscopy (CLSM) for characterizing simulated bilge water emulsions with different types of surfactants (Triton X-100 and sodium dodecyl sulfate [SDS]) under various NaCl concentrations at microscale...
September 1, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28803326/short-term-results-of-endovascular-surgery-with-tissue-plasminogen-activator-injection-for-central-retinal-vein-occlusion
#9
Masaaki Ishida, Shinya Abe, Takuya Nakagawa, Atsushi Hayashi
PURPOSE: To examine the effects of retinal endovascular surgery (REVS) with tissue plasminogen activator injection into the retinal vein in central retinal vein occlusion (CRVO) eyes. METHODS: Sixteen consecutive CRVO patients with macular edema and decreased visual acuity who were referred to Toyama University Hospital between March 2014 and February 2016 were included in this study. Changes in visual acuity (VA) and central retinal thickness (CRT) were evaluated up to 6 months after REVS...
August 12, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28790007/targeted-epidural-blood-patch-under-o-arm-guided-stereotactic-navigation-in-patients-with-intracranial-hypotension-associated-with-a-spinal-csf-leak-and-ventral-dural-defect
#10
Keisuke Takai, Makoto Taniguchi
OBJECTIVE: Targeted epidural blood patch (EBP) at the site of a presumed cerebrospinal fluid leak reportedly has better outcomes than non-targeted EBP; however, it is associated with a higher risk of wrong-site injection such as iatrogenic subarachnoid or intramuscular injections, which lead to reintervention due to the insufficient coverage of injected blood. METHODS: Eight patients with intracranial hypotension due to a CSF leak diagnosed by myelographic CT and thin-cut MRI received an epidural blood patch under O-arm-guided stereotactic navigation...
August 5, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28773074/synthesis-of-al%C3%A2-ca-dispersoids-by-powder-metallurgy-using-a-mg-al-alloy-and-cao-particles
#11
Junji Fujita, Junko Umeda, Katsuyoshi Kondoh
The elemental mixture of Mg-6 wt %Al-1 wt %Zn-0.3 wt %Mn (AZ61B) alloy powder and CaO particles was consolidated by an equal-channel angular bulk mechanical alloying (ECABMA) process to form a composite precursor. Subsequently, the precursor was subjected to a heat treatment to synthesize fine Al₂Ca particles via a solid-state reaction between the Mg-Al matrix and CaO additives. Scanning electron microscopy-energy-dispersive spectroscopy (SEM-EDS) and electron probe micro-analysis on the precursor indicated that 4...
June 28, 2017: Materials
https://www.readbyqxmd.com/read/28743235/magnetic-hyperthermia-enhance-the-treatment-efficacy-of-peri-implant-osteomyelitis
#12
Chih-Hsiang Fang, Pei-I Tsai, Shu-Wei Huang, Jui-Sheng Sun, Jenny Zwei-Chieng Chang, Hsin-Hsin Shen, San-Yuan Chen, Feng Huei Lin, Lih-Tao Hsu, Yen-Chun Chen
BACKGROUND: When bacteria colony persist within a biofilm, suitable drugs are not yet available for the eradication of biofilm-producing bacteria. The aim of this study is to study the effect of magnetic nano-particles-induced hyperthermia on destroying biofilm and promoting bactericidal effects of antibiotics in the treatment of osteomyelitis. METHODS: Sixty 12-weeks-old male Wistar rats were used. A metallic 18G needle was implanted into the bone marrow cavity of distal femur after the injection of Methicillin-sensitive Staphylococcus aureus (MSSA)...
July 25, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28725251/custom-made-micro-applicators-for-high-dose-rate-brachytherapy-treatment-of-chronic-psoriasis
#13
Ivan M Buzurovic, Desmond A O'Farrell, Mandar S Bhagwat, Jorgen L Hansen, Thomas C Harris, Scott Friesen, Robert A Cormack, Phillip M Devlin
PURPOSE: In this study, we present the treatment of the psoriatic nail beds of patients refractory to standard therapies using high-dose-rate (HDR) brachytherapy. The custom-made micro applicators (CMMA) were designed and constructed for radiation dose delivery to small curvy targets with complicated topology. The role of the HDR brachytherapy treatment was to stimulate the T cells for an increased immune response. MATERIAL AND METHODS: The patient diagnosed with psoriatic nail beds refractory to standard therapies received monthly subunguinal injections that caused significant pain and discomfort in both hands...
June 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/28696572/evaluation-of-electrical-impedance-spectroscopy-on-a-needle-as-a-novel-tool-to-determine-optimal-surgical-margin-in-partial-nephrectomy
#14
Hyeon Woo Kim, Joho Yun, Jeong Zoo Lee, Dong Gil Shin, Jong-Hyun Lee
A hypodermic needle has been introduced incorporating an electrical impedance spectroscopy (EIS) sensor, called micro-EIS-on-a-needle for depth profiling (μEoN-DP). The μEoN-DP can locate endophytic renal tumors as well as determine tumor margins by detecting the impedance difference between normal and cancer tissues. To evaluate the μEoN-DP as a novel tool to determine the optimal surgical margin during partial nephrectomy (PN), the electrical impedance differences between renal parenchymal tissues and renal cell carcinoma (RCC) tumors are investigated with regard to the distance from the tumors...
July 11, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28657367/the-self-recovery-of-facial-skin-barrier-and-erythema-after-nanochip-treatment
#15
Yan Ling Tao, Afzaal Ahmed Bin Jameel, Ying Ying Miao, Bai Xu, Yan Ting Wu, Juan Liu, Bing Rong Zhou, Dan Luo
OBJECTIVE: To determine the degree of acute skin damage and the time required for the recovery of facial skin barrier function after the skin was treated with microneedles and nanochips of various tip lengths. METHODS: For this split face comparative study, a total of 16 subjects were enrolled and radomly divided into 2 groups. In the first group, one of the facial side of each subject was treated with 0.25 mm long nanotips for a total of 6 times while the other facial side was treated with 0...
June 28, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28647883/casper-computer-aided-segmentation-of-imperceptible-motion-a-learning-based-tracking-of-an-invisible-needle-in-ultrasound
#16
Parmida Beigi, Robert Rohling, Septimiu E Salcudean, Gary C Ng
PURPOSE: This paper presents a new micro-motion-based approach to track a needle in ultrasound images captured by a handheld transducer. METHODS: We propose a novel learning-based framework to track a handheld needle by detecting microscale variations of motion dynamics over time. The current state of the art on using motion analysis for needle detection uses absolute motion and hence work well only when the transducer is static. We have introduced and evaluated novel spatiotemporal and spectral features, obtained from the phase image, in a self-supervised tracking framework to improve the detection accuracy in the subsequent frames using incremental training...
June 24, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28645718/optimizing-adjuvants-for-intradermal-delivery-of-menc-glycoconjugate-vaccine
#17
Agnese Donadei, Cristiana Balocchi, Maria R Romano, Luigi Panza, Roberto Adamo, Francesco Berti, Derek T O'Hagan, Simona Gallorini, Barbara C Baudner
Intradermal vaccine delivery is a promising alternative to the conventional intramuscular route. The skin layer is immunologically supported by a densely network of antigen presenting cells, while the skeletal muscle is loaded with a relatively sparse population of APCs. Nevertheless, the vaccine to be suitable for intradermal delivery needs a new formulation to facilitate either smaller injection volumes or the introduction into new delivery devises as micro-needles. This study presents a proof of concept for intradermal delivery of the MenC-CRM197 glycoconjugate vaccine using a mouse model...
July 13, 2017: Vaccine
https://www.readbyqxmd.com/read/28628624/heterogeneity-of-mirna-expression-in-localized-prostate-cancer-with-clinicopathological-correlations
#18
Ahmed Hussein Zedan, Søren Garm Blavnsfeldt, Torben Frøstrup Hansen, Boye Schnack Nielsen, Niels Marcussen, Mindaugas Pleckaitis, Palle Jörn Sloth Osther, Flemming Brandt Sørensen
INTRODUCTION: In the last decade microRNAs (miRNAs) have been widely investigated in prostate cancer (PCa) and have shown to be promising biomarkers in diagnostic, prognostic and predictive settings. However, tumor heterogeneity may influence miRNA expression. The aims of this study were to assess the impact of tumor heterogeneity, as demonstrated by a panel of selected miRNAs in PCa, and to correlate miRNA expression with risk profile and patient outcome. MATERIAL AND METHODS: Prostatectomy specimens and matched, preoperative needle biopsies from a retrospective cohort of 49 patients, who underwent curatively intended surgery for localized PCa, were investigated with a panel of 6 miRNAs (miRNA-21, miRNA-34a, miRNA-125b, miRNA-126, miRNA-143, and miRNA-145) using tissue micro-array (TMA) and in situ hybridization (ISH)...
2017: PloS One
https://www.readbyqxmd.com/read/28622807/the-comparison-of-the-effects-of-a-novel-hydrogel-compound-and-traditional-hyaluronate-following-micro-fracture-procedure-in-a-rat-full-thickness-chondral-defect-model
#19
Yunus Emre Akman, Erhan Sukur, Ahmet Senel, Nur Ece Oztas Sukur, Canan Kelten Talu, Yusuf Ozturkmen
PURPOSE: The aim of this experimental study was to investigate the impact of HA-CS-NAG compound (hyaluronate, sodium chondroitin sulfate, N-acetyl-d-glucosamine) on the quality of repair tissue after micro-fracture and to compare it with HA (hyaluronat), in a rat full-thickness chondral defect model. METHODS: Full-thickness chondral defects were created in a non-weight bearing area by using a handle 2.7-mm drill bit, in the right knees of 33 Sprague-Dawley rats...
June 13, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28622082/comparing-the-effectiveness-of-fractional-co2-laser-and-the-combination-therapy-with-micro-needling-and-topical-10-trichloroacetic-acid-to-remove-infra-orbital-dark-circles-in-tehran-women
#20
Abbas Zamanian, Mahba Azizi, Mohamadreza Ghasemi, Elham Behrangi, Sedigheh Naeji
BACKGROUND: Infra-orbital dark circles in now identified as a cosmetic problem which should be considered in treatment issue. The present study aimed to assess and compare the clinical efficiency of the combination of micro-needling and 10% trichloroacetic acid (TCA) cream as well as carbon dioxide laser in the management of infra-orbital dark circles. METHODS: This randomized clinical trial was performed on women ranged 28 to 62 years that complained of infra-orbital dark circles...
June 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
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