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https://www.readbyqxmd.com/read/28346894/the-romberg-ratio-in-people-with-multiple-sclerosis
#1
Alon Kalron
Postural control relies on the integration of inputs from the visual, somatosensory and vestibular systems which are frequently impaired in people with Multiple Sclerosis (PwMS). In this situation, examining the Romberg ratio can be useful. This parameter can be interpreted as a gross indicator of a vestibular and proprioceptive contribution to postural control. Therefore, the primary objective of the current study was to examine whether the Romberg ratio differs between MS fallers, non-fallers and neurological disability levels...
March 14, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28346822/sensitivity-analysis-for-matched-pair-analysis-of-binary-data-from-worst-case-to-average-case-analysis
#2
Raiden Hasegawa, Dylan Small
In matched observational studies where treatment assignment is not randomized, sensitivity analysis helps investigators determine how sensitive their estimated treatment effect is to some unmeasured confounder. The standard approach calibrates the sensitivity analysis according to the worst case bias in a pair. This approach will result in a conservative sensitivity analysis if the worst case bias does not hold in every pair. In this paper, we show that for binary data, the standard approach can be calibrated in terms of the average bias in a pair rather than worst case bias...
March 27, 2017: Biometrics
https://www.readbyqxmd.com/read/28346753/association-between-diabetes-mellitus-hyperglycemia-and-peri-implant-diseases-systematic-review-and-meta-analysis
#3
REVIEW
Alberto Monje, Andres Catena, Wenche S Borgnakke
AIM: This systematic review investigates whether hyperglycemia/diabetes mellitus is associated with peri-implant diseases (peri-implant mucositis and peri-implantitis). MATERIALS AND METHODS: Electronic and manual literature searching was conducted. An a priori case definition for peri-implantitis was used as an inclusion criterion to minimize risk of bias. The Newcastle Ottawa Scale was used for quality assessment; random effect models were applied; and results were reported according to the PRISMA Statement...
March 27, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28346748/the-brain-of-the-giraffe-giraffa-camelopardalis-surface-configuration-encephalization-quotient-and-analysis-of-the-existing-literature
#4
Jean-Marie Graïc, Antonella Peruffo, Cristina Ballarin, Bruno Cozzi
The anatomy of the giraffe (Giraffa camelopardalis Linnaeus, 1758) has been poorly studied, except for the circulatory system. In particular, only a handful of studies have concerned the brain of this species since the first description in 1839. Accordingly, only a very few articles discussing encephalization mentioned the giraffe or used it in their calculations. In this article, we performed a thorough examination of the literature including old and grey, regarding the central nervous system of the giraffe...
March 27, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28346747/agreement-between-cytotechnologists-and-cytopathologists-as-a-new-measure-of-cytopathologist-performance-in-gynecologic-cytology
#5
Andrew M Quinn, Abu T Minhajuddin, Linda S Hynan, Joan S Reisch, Edmund S Cibas
BACKGROUND: Although objective measures of cytotechnologist (CT) and cytopathologist (CP) performance exist, challenges remain. Two assumptions deserve examination: CPs' interpretations are correct, and CTs and CPs render interpretations independently of each other. This study presents a CT-CP interpretation comparison and provides insight into these assumptions. METHODS: Every gynecologic cytology specimen examined by both a CT and a CP from December 2004 to March 2015 was extracted from the laboratory information system; glandular interpretations were excluded...
March 27, 2017: Cancer
https://www.readbyqxmd.com/read/28346606/evidence-based-redesign-of-the-comlex-usa-series
#6
John R Gimpel, Dorothy Horber, Jeanne M Sandella, Janice A Knebl, John E Thornburg
To ensure that the Comprehensive Osteopathic Medical Licensing Examination-USA (COMLEX-USA) reflects the evolving practice of osteopathic medicine, the National Board of Osteopathic Medical Examiners has developed new content and format specifications for an enhanced, competency-based examination program to be implemented with COMLEX-USA Level 3 in 2018. This article summarizes the evidence-based design processes that served as the foundation for blueprint development and the evidence supporting its validity...
April 1, 2017: Journal of the American Osteopathic Association
https://www.readbyqxmd.com/read/28346595/association-of-gastric-acid-suppression-with-recurrent-clostridium-difficile-infection-a-systematic-review-and-meta-analysis
#7
Raseen Tariq, Siddharth Singh, Arjun Gupta, Darrell S Pardi, Sahil Khanna
Importance: Gastric acid suppression has been associated with an increased risk of primary Clostridium difficile infection (CDI), but the risk of recurrent CDI in patients taking gastric acid suppressant medications is unclear. Objective: To perform a systematic review and meta-analysis to evaluate the association between gastric acid suppressants and recurrent CDI. Data Sources: MEDLINE, EMBASE, the Cochrane Central Register, the Cochrane Database, and Web of Science were searched from January 1, 1995, to September 30, 2015, for studies assessing the association between gastric acid suppressant exposure and recurrent CDI...
March 27, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28346432/nanoscale-capillary-freezing-of-ionic-liquids-confined-between-metallic-interfaces-and-the-role-of-electronic-screening
#8
Jean Comtet, Antoine Niguès, Vojtech Kaiser, Benoit Coasne, Lydéric Bocquet, Alessandro Siria
Room-temperature ionic liquids (RTILs) are new materials with fundamental importance for energy storage and active lubrication. They are unusual liquids, which challenge the classical frameworks of electrolytes, whose behaviour at electrified interfaces remains elusive, with exotic responses relevant to their electrochemical activity. Using tuning-fork-based atomic force microscope nanorheological measurements, we explore here the properties of confined RTILs, unveiling a dramatic change of the RTIL towards a solid-like phase below a threshold thickness, pointing to capillary freezing in confinement...
March 27, 2017: Nature Materials
https://www.readbyqxmd.com/read/28346419/evolving-concepts-in-prognostic-scoring-of-chronic-gvhd
#9
REVIEW
A Lazaryan, M Arora
Chronic GvHD (cGvHD) remains one of the most complex and challenging complications after allogeneic hematopoietic cell transplantation. Emerging knowledge about the clinical manifestations and associated organ involvement of cGvHD has led to the establishment of prognostic parameters for post-transplant survival among affected allograft recipients. Studies employing the pre-National Institutes of Health (NIH) consensus data on cGvHD incidence and its risks have led to development of the CIBMTR's cGvHD risk stratification, which serves as the most refined and validated prognostic tool for estimating survival of patients with cGvHD...
March 27, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28346380/constituents-of-the-roots-of-dichapetalum-pallidum-and-their-anti-proliferative-activity
#10
Dorcas Osei-Safo, Godwin Akpeko Dziwornu, Regina Appiah-Opong, Mary Anti Chama, Isaac Tuffour, Reiner Waibel, Richard Amewu, Ivan Addae-Mensah
As part of our search for bioactive compounds from the Dichapetalaceae, repeated chromatographic purification of the roots of a hitherto unexamined species, Dichapetalum pallidum, led to the isolation of the newly occurring 7-hydroxydichapetalin P (1) and the known dichapetalins A (2) and X (3). Also isolated were the known compounds friedelin-2,3-lactone (4), friedelan-3-one (6), friedelan-3β-ol (7) and pomolic (8), as well as the dipeptide aurantiamide acetate (5). The compounds were characterized by direct interpretation of their IR, 1D NMR and 2D NMR spectral data and by comparison of their physico-chemical data, including their chromatographic profiles, with the literature and authentic samples in our compound library for the genus Dichapetalum...
March 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28346343/lifetime-exposure-to-a-constant-environment-amplifies-the-impact-of-a-fructose-rich-diet-on-glucose-homeostasis-during-pregnancy
#11
Aleida Song, Stuart Astbury, Abha Hoedl, Brent Nielsen, Michael E Symonds, Rhonda C Bell
The need to refine rodent models of human-related disease is now being recognized, in particular the rearing environment that can profoundly modulate metabolic regulation. Most studies on pregnancy and fetal development purchase and transport young females into the research facility, which after a short period of acclimation are investigated (Gen0). We demonstrate that female offspring (Gen1) show an exaggerated hyperinsulinemic response to pregnancy when fed a standard diet and with high fructose intake, which continues throughout pregnancy...
March 25, 2017: Nutrients
https://www.readbyqxmd.com/read/28346329/cardiac-computed-tomography-radiomics-a-comprehensive-review-on-radiomic-techniques
#12
Márton Kolossváry, Miklós Kellermayer, Béla Merkely, Pál Maurovich-Horvat
Radiologic images are vast three-dimensional data sets in which each voxel of the underlying volume represents distinct physical measurements of a tissue-dependent characteristic. Advances in technology allow radiologists to image pathologies with unforeseen detail, thereby further increasing the amount of information to be processed. Even though the imaging modalities have advanced greatly, our interpretation of the images has remained essentially unchanged for decades. We have arrived in the era of precision medicine where even slight differences in disease manifestation are seen as potential target points for new intervention strategies...
March 24, 2017: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/28346251/histological-mohs-maps-improve-the-accuracy-of-dermatology-residents-interpretations-of-mohs-slides-a-pilot-study
#13
Jeffrey B Tiger, Zai Ganesh, John Mouzakis, Satori Iwamoto
BACKGROUND: Effective Mohs surgery depends on accurate histopathological identification and mapping of tumor burden to ensure complete removal of tumor. OBJECTIVE: The purpose of this study is to evaluate whether using a photograph of the histopathological slide as the Mohs map improves mapping accuracy. METHODS AND MATERIALS: Single-blinded pilot study. Five dermatology residents at one academic institution mapped 11 cases of basal cell carcinoma using both traditional hand-drawn maps and color photographic maps...
March 23, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28346234/outstanding-animal-studies-in-allergy-i-from-asthma-to-food-allergy-and-anaphylaxis
#14
Erika Jensen-Jarolim, Isabella Pali-Schöll, Franziska Roth-Walter
PURPOSE OF REVIEW: Animal models published within the past 18 months on asthma, food allergy and anaphylaxis, all conditions of rising public health concern, were reviewed. RECENT FINDINGS: While domestic animals spontaneously develop asthma, food allergy and anaphylaxis, in animal models, divergent sensitization and challenge routes, dosages, intervals and antigens are used to induce asthmatic, food allergic or anaphylactic phenotypes. This must be considered in the interpretation of results...
March 24, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28346124/pax8-napsin-a-and-cd10-as-immunohistochemical-markers-of-canine-renal-cell-carcinoma
#15
Tyler J Peat, Elijah F Edmondson, Margaret A Miller, Dee M DuSold, José A Ramos-Vara
Pax8, napsin A, and CD10 are useful immunohistochemical markers of human renal cell carcinoma (RCC); however, their diagnostic utility in canine RCC is unclear. Forty formalin-fixed paraffin-embedded renal cell carcinomas from dogs (15 papillary, 12 solid, and 13 tubular) and 10 metastases were evaluated for expression of Pax8, napsin A, and CD10. Thirty-nine (98%), 24 (60%), and 19 (50%) tumors expressed Pax8 (nuclear labeling), napsin A (cytoplasmic labeling), and CD10 (cytoplasmic and membranous labeling), respectively...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28346076/meaning-making-after-a-near-death-experience-the-relevance-of-intrapsychic-and-interpersonal-dynamics
#16
Simone Bianco, Marco Sambin, Arianna Palmieri
This study aims to investigate the processes used by individuals to integrate a near-death experience (NDE), and to discuss the use of a meaning-making component to help people who have had such experiences. A psychotherapist interviewed six individuals who reported having had a NDE. Transcripts of the interviews were coded using an interpretative phenomenological analysis. We identified intrapsychic and interpersonal dynamics implicated in the individuals' meaning-making processes, and the problems encountered during their integration of the experience...
March 27, 2017: Death Studies
https://www.readbyqxmd.com/read/28346067/horseback-riding-therapy-for-a-deafblind-individual-enabled-by-a-haptic-interface
#17
Matjaž Ogrinc Ms, Ildar Farkhatdinov PhD, Rich Walker Ms, Etienne Burdet
We present a haptic interface to help deafblind people to practice horseback riding as a recreational and therapeutic activity. Horseback riding is a form of therapy which can improve self-esteem and sensation of independence. It has been shown to benefit people with various medical conditions-including autism. However, in the case of deafblind riders, an interpreter must stand by at all times to communicate with the rider by touch. We developed a simple interface that enables deafblind people to enjoy horseback riding while the instructor is remotely providing cues, which improves their independence...
March 27, 2017: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/28346061/understanding-the-contamination-of-food-with-mineral-oil-the-need-for-a-confirmatory-analytical-and-procedural-approach
#18
Lionel W Spack, Gabriela Leszczyk, Jesus Varela, Hervé Simian, Thomas Gude, Richard H Stadler
The contamination of food by mineral oil hydrocarbons (MOH) found in packaging is a long running concern. A main source of MOH in foods is the migration of mineral oil from recycled board into the packed food products. Consequently, the majority of food manufacturers have taken protective measures, for example by using virgin board instead of recycled fibers, and where feasible, introducing functional barriers to mitigate migration. Despite these protective measures, MOH may still be observed at low amounts in certain food products, albeit due to different entry points across the food supply chain...
March 27, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28346041/enhancing-tolerability-of-a-measure-of-social-perception-in-schizophrenia-comparison-of-short-and-long-norwegian-versions-of-the-relationships-across-domains-test
#19
Anja Vaskinn, Alan P Fiske, Michael F Green
INTRODUCTION: Relationship perception focuses on social interactions, is reduced in schizophrenia and is related to daily functioning. It can be assessed with the Relationships Across Domains (RAD) test, built on Relational Models Theory which states that people use four relational models to interpret social interaction. RAD is time consuming, low on tolerability and only used in English-speaking countries. We evaluated the psychometric properties of a translated, abbreviated Norwegian version...
March 27, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28345954/chest-radiographic-screening-for-sarcoidosis-in-the-diagnosis-of-patients-with-active-uveitis
#20
Fahriye Groen, Jan A M van Laar, Aniki Rothova
RATIONALE: Although chest radiography is currently recommended for the initial evaluation of patients with new onset uveitis, the efficacy of this diagnostic screening modality is not known. OBJECTIVES: To evaluate the diagnostic value of chest radiographs in patients with active uveitis of recent onset in a tertiary center in Western Europe. METHODS: A retrospective cross-sectional study was conducted by reviewing all chest imaging for adults with new onset (<1 year) uveitis of unknown origin undergoing initial evaluation in the Department of Ophthalmology at Erasmus University Medical Center (Rotterdam, the Netherlands)...
March 27, 2017: Annals of the American Thoracic Society
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