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https://www.readbyqxmd.com/read/29908523/radiographic-study-of-haematogenous-septic-arthritis-in-dairy-calves
#1
Caroline Constant, Isabelle Masseau, Marie Babkine, Sylvain Nichols, David Francoz, Gilles Fecteau, Emma Marchionatti, Helene Larde, Andre Desrochers
OBJECTIVES:  (1) To develop an evaluation grid to provide a systematic interpretation of calves' articular radiographs, (2) to describe radiographic lesions of septic arthritis in dairy calves less than 6 months of age, (3) to investigate potential associations between demographic data or synovial bacteriological culture results and radiographic lesions (4) to determine whether an association is present between radiographic lesions, their severity and the long-term outcome. METHODS:  Medical records of 54 calves less than 180 days old treated for septic arthritis between 2009 and 2014 with radiographic images performed in the first 2 days after admission were reviewed...
June 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29908517/high-sensitive-cardiac-troponin-hs-tnt-levels-in-sudden-deaths-related-to-atherosclerotic-coronary-artery-disease
#2
Tim Beausire, Mohamed Faouzi, Cristian Palmiere, Tony Fracasso, Katarzyna Michaud
INTRODUCTION: Ischemic heart disease (IHD) related to atherosclerotic coronary artery disease (CAD) is one of the most prevalent causes of death in Europe. Postmortem evaluation of IHD remains a challenge because of possible non-specific autopsy finding in some autopsy cases, especially in early myocardial ischemia. High-sensitive cardiac troponin T (hs-TnT) is used today in clinical practice as the "gold standard" to diagnose the myocardial ischemia, and might also be applied as an ancillary tool for post-mortem evaluation...
June 4, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29908470/chromatographic-test-methods-for-characterizing-alkylsiloxane-bonded-silica-columns-for-reversed-phase-liquid-chromatography
#3
REVIEW
Colin F Poole
Major obstacles to formulating a simple retention mechanism for reversed-phase liquid chromatography have a direct impact on the development of experimental methods for column characterization as they limit our capability to understand observed differences in retention at a system level. These problems arise from the heterogeneous composition of the stationary phase, the difficulty of providing a working definition for the phase ratio, and uncertainty as to whether the distribution mechanism for varied compounds is a partition, adsorption or mixed (combination) of these models...
June 7, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29908431/smoking-ban-and-health-at-birth-evidence-from-hungary
#4
Tamás Hajdu, Gábor Hajdu
In 2012, smoking restrictions were extended to hospitality venues in Hungary. Women working in bars and restaurants were primarily affected by the intervention. In this research, we analyze the effect of this smoking ban on the outcomes of their pregnancies. Using individual live birth, fetal loss, and infant mortality registry data, we examine the probability of live birth, indicators of health at birth, and the probability of death in the first year of life. We apply a difference-in-differences framework and show that the smoking ban has improved health at birth...
June 13, 2018: Economics and Human Biology
https://www.readbyqxmd.com/read/29908392/differences-between-self-and-peer-rated-likability-in-relation-to-social-anxiety-and-depression-in-adolescents-with-mild-intellectual-disabilities
#5
Anke M Klein, Esther O Houtkamp, Elske Salemink, Jeanine M D Baartmans, Mike Rinck, Mariët J van der Molen
BACKGROUND: Social anxiety and depressive symptoms are relatively common in adolescents with Mild to Borderline Intellectual Disabilities (MBID). Unfortunately, there are only a few studies that focus on examining processes underlying social anxiety and depression in these adolescents. AIMS: The aim was to examine the differences between self- and peer-rated likability in relation to social anxiety and depression in the classroom environment. METHODS AND PROCEDURES: 631 normative non-clinical adolescents with MBID completed questionnaires to measure social anxiety, depression, and the estimation of their own likability by peers...
June 13, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29908360/heterogeneity-in-clinical-endoscopic-and-histologic-outcome-measures-and-placebo-response-rates-in-clinical-trials-of-eosinophilic-esophagitis-a-systematic-review
#6
REVIEW
Christopher Ma, Bram D van Rhijn, Vipul Jairath, Tran M Nguyen, Claire E Parker, Seema S Aceves, Glenn T Furuta, Sandeep K Gupta, David A Katzka, Ekaterina Safroneeva, Alain M Schoepfer, Alex Straumann, Jonathan M Spergel, Rish K Pai, Brian G Feagan, Ikuo Hirano, Evan S Dellon, Albert J Bredenoord
BACKGROUND & AIMS: Agents are being developed for treatment of eosinophilic esophagitis (EoE). However, it is not clear what outcome measures would best determine the efficacy and safety of these agents in clinical trials. We performed a systematic review of outcomes used in randomized placebo-controlled trials of EoE and we estimate the placebo response and rates of remission. METHODS: We searched MEDLINE, Embase, CENTRAL, ClinicalTrials.gov, and the EU Clinical Trials Register from inception through February 20, 2018 for randomized controlled trials of pharmacologic therapies for EoE...
June 13, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29908250/immunochromatographic-test-for-rapid-serological-diagnosis-of-human-angiostrongyliasis
#7
Praphathip Eamsobhana, Anchalee Tungtrongchitr, Darawan Wanachiwanawin, Hoi-Sen Yong
OBJECTIVES: The serological diagnosis of human infection with Angiostrongylus cantonensis remains problematic because there are no commercially available validated tests. Most laboratories use domestically prepared tests such as the enzyme-linked immunosorbent assay (ELISA) or immunoblotting. Since laboratory facilities are not always available in endemic areas, we developed and assessed a rapid lateral flow immunochromatographic assay (AcQuickDx Test) to detect anti-A. cantonensis antibodies in human serum...
June 13, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29907933/the-effect-of-time-of-flight-and-point-spread-function-modeling-on-82-rb-myocardial-perfusion-imaging-of-obese-patients
#8
Paul K R Dasari, Judson P Jones, Michael E Casey, Yuanyuan Liang, Vasken Dilsizian, Mark F Smith
BACKGROUND: The effect of time-of-flight (TOF) and point spread function (PSF) modeling in image reconstruction has not been well studied for cardiac PET. This study assesses their separate and combined influence on 82 Rb myocardial perfusion imaging in obese patients. METHODS: Thirty-six obese patients underwent rest-stress 82 Rb cardiac PET. Images were reconstructed with and without TOF and PSF modeling. Perfusion was quantitatively compared using the AHA 17-segment model for patients grouped by BMI, cross-sectional body area in the scanner field of view, gender, and left ventricular myocardial volume...
June 15, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29907925/retest-effects-in-working-memory-capacity-tests-a-meta-analysis
#9
REVIEW
Jana Scharfen, Katrin Jansen, Heinz Holling
The repeated administration of working memory capacity tests is common in clinical and research settings. For cognitive ability tests and different neuropsychological tests, meta-analyses have shown that they are prone to retest effects, which have to be accounted for when interpreting retest scores. Using a multilevel approach, this meta-analysis aims at showing the reproducibility of retest effects in working memory capacity tests for up to seven test administrations, and examines the impact of the length of the test-retest interval, test modality, equivalence of test forms and participant age on the size of retest effects...
June 15, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29907846/greater-blood-volume-and-hb-mass-in-obese-women-quantified-by-the-carbon-monoxide-rebreathing-method-affects-interpretation-of-iron-biomarkers-and-iron-requirements
#10
Ana C Cepeda-Lopez, Michael B Zimmermann, Sophia Wussler, Alida Melse-Boonstra, Nicole Naef, Sandro Manuel Mueller, Marco Toigo, Isabelle Herter-Aeberli
BACKGROUND/OBJECTIVE: Iron deficiency (ID) is common in overweight and obese individuals (OW/OB) but the mechanism is uncertain. Greater blood volume (BV) in OW/OB may increase hemoglobin (Hb) mass and iron requirements, and confound iron biomarkers by hemodilution. Quantification of BV/PV changes in OW/OB is challenging and a formula to estimate BV/PV based on anthropometric indices would be valuable. In normal weight (NW) and OW/OB women, we aimed at: (1) measure BV and assess whether differences in BV affect concentrations and total circulating mass of Hb and iron biomarkers; (2) develop an algorithm describing BV in OW/OB...
June 15, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29907818/speckle-tracking-stress-echocardiography-in-children-interobserver-and-intraobserver-reproducibility-and-the-impact-of-echocardiographic-image-quality
#11
Lucia Wilke, Francisca E Abellan Schneyder, Markus Roskopf, Andreas C Jenke, Andreas Heusch, Kai O Hensel
Speckle tracking echocardiography (STE) is increasingly used during functional assessments. However, reproducibility and dependence on echocardiographic image quality for speckle tracking stress echocardiography in pediatric patients have not been studied to date. 127 consecutive normotensive children without structural heart disease (mean age 13.4 ± 3.0 years, 50.4% female) underwent a stepwise semisupine cycle ergometric protocol. Left ventricular (LV) myocardial peak strain and strain rate were assessed at rest and during exercise...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907745/spatter-matters-distinguishing-primary-eruptive-and-secondary-non-eruptive-spatter-deposits
#12
T J Jones, B F Houghton, E W Llewellin, C E Parcheta, L Höltgen
Spatter is a common pyroclastic product of hawaiian fountaining, which typically forms vent-proximal ramparts or cones. Based on textural characteristics and field relations of spatter from the 1969 Mauna Ulu eruption of Kīlauea, Hawai'i, three spatter types were identified: (1) Primary spatter deposited as spatter ramparts and isolated cones during the peak of episode 1; (2) Late-stage spatter comprising dense, small volume, vent proximal deposits, formed at the end of episode 1; (3) Secondary spatter preserved in isolated mounds around tectonic ground cracks that we interpret to have formed by the disruption of overlying lava...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907681/case-studies-of-gastric-lung-and-oral-cancer-connect-etiologic-agent-prevalence-to-cancer-incidence
#13
Andrew F Brouwer, Marisa C Eisenberg, Rafael Meza
Obtaining detailed individual-level data on both exposure and cancer outcomes is challenging, and it is difficult to understand and characterize how temporal aspects of exposures translate into cancer risk. We show that, in lieu of individual-level information, population-level data on cancer incidence and etiologic agent prevalence can be leveraged to investigate cancer mechanisms and to better characterize and predict cancer trends. We use mechanistic carcinogenesis models [multistage clonal expansion (MSCE) models] and data on smoking, Helicobacter pylori ( H...
June 15, 2018: Cancer Research
https://www.readbyqxmd.com/read/29907639/t-type-calcium-channels-in-the-orbitofrontal-cortex-mediate-sensory-integration-as-measured-using-a-spontaneous-oddity-task-in-rats
#14
Wendie N Marks, Madeline E Parker, Nadine K Zabder, Quentin Greba, Terrance P Snutch, John G Howland
The roles of low-voltage-activated (T-type) calcium channels in brain diseases have been studied extensively. Less is known regarding the involvement of T-type channels in cognition and behavior. Sensory integration (SI) is a cognitive process whereby the brain uses unimodal or multimodal sensory features to create a comprehensive representation of the environment. The multisensory object oddity (MSO) task assesses SI using combinations of sensory features of objects, either in the same or different sensory modalities...
July 2018: Learning & Memory
https://www.readbyqxmd.com/read/29907541/therapeutic-tattooing-in-the-arctic-ethnographic-archaeological-and-ontological-frameworks-of-analysis
#15
Lars Krutak
This essay describes the potential for using ethnographic evidence and mummified tattooed skin to reflect on past therapeutic tattoo practice in the Arctic. It also considers the ways in which circumpolar concepts of disease emerged in relation to the agency of nonhuman entities. I argue that specific forms of curative tattooing offer interpretive models for the paleopathological and bioarchaeological study of care through an ontological framework of analysis.
June 12, 2018: International Journal of Paleopathology
https://www.readbyqxmd.com/read/29907533/perinatal-care-needs-and-expectations-of-women-with-low-vision-or-total-blindness-in-warsaw-poland
#16
Barbara Mazurkiewicz, Małgorzata Stefaniak, Ewa Dmoch-Gajzlerska
BACKGROUND: As estimated from the number of published studies, in Poland the research into the perinatal care experiences of women with low vision or total blindness remains limited. OBJECTIVES: The purpose of the study was to fill this gap by investigating satisfaction with perinatal care received by women with visual impairment in four city hospitals in Warsaw, Poland, and to recommend, if required, modifications in midwives' education and care standards based on the women's perceptions and expectations...
June 12, 2018: Disability and Health Journal
https://www.readbyqxmd.com/read/29907351/dietary-sodium-sodium-to-potassium-ratio-and-risk-of-stroke-a-systematic-review-and-nonlinear-dose-response-meta-analysis
#17
Ahmad Jayedi, Farnoosh Ghomashi, Mahdieh Sadat Zargar, Sakineh Shab-Bidar
BACKGROUND & AIMS: The association of high sodium intake with risk of stroke has been accepted. But considering the proposed J/U-shaped association between sodium intake and risk of all-cause mortality, the shape of the dose-response relationship has not been determined yet. This study aimed to test the dose-response association of dietary sodium and sodium-to-potassium ratio with risk of stroke in adults aged 18 years or older. METHODS: We performed a systematic search using PubMed and Scopus, from database inception up to October 2017...
June 1, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29907338/artificial-intelligence-in-radiation-oncology-a-specialty-wide-disruptive-transformation
#18
REVIEW
Reid F Thompson, Gilmer Valdes, Clifton D Fuller, Colin M Carpenter, Olivier Morin, Sanjay Aneja, William D Lindsay, Hugo J W L Aerts, Barbara Agrimson, Curtiland Deville, Seth A Rosenthal, James B Yu, Charles R Thomas
Artificial intelligence (AI) is emerging as a technology with the power to transform established industries, and with applications from automated manufacturing to advertising and facial recognition to fully autonomous transportation. Advances in each of these domains have led some to call AI the "fourth" industrial revolution [1]. In healthcare, AI is emerging as both a productive and disruptive force across many disciplines. This is perhaps most evident in Diagnostic Radiology and Pathology, specialties largely built around the processing and complex interpretation of medical images, where the role of AI is increasingly seen as both a boon and a threat...
June 12, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29907290/comprehensive-evaluation-of-untargeted-metabolomics-data-processing-software-in-feature-detection-quantification-and-discriminating-marker-selection
#19
Zhucui Li, Yan Lu, Yufeng Guo, Haijie Cao, Qinhong Wang, Wenqing Shui
Data analysis represents a key challenge for untargeted metabolomics studies and it commonly requires extensive processing of more than thousands of metabolite peaks included in raw high-resolution MS data. Although a number of software packages have been developed to facilitate untargeted data processing, they have not been comprehensively scrutinized in the capability of feature detection, quantification and marker selection using a well-defined benchmark sample set. In this study, we acquired a benchmark dataset from standard mixtures consisting of 1100 compounds with specified concentration ratios including 130 compounds with significant variation of concentrations...
October 31, 2018: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29907276/device-management-and-flow-optimization-on-left-ventricular-assist-device-support
#20
REVIEW
Inna Tchoukina, Melissa C Smallfield, Keyur B Shah
The authors discuss principles of continuous flow left ventricular assist device (LVAD) operation, basic differences between the axial and centrifugal flow designs and hemodynamic performance, normal LVAD physiology, and device interaction with the heart. Systematic interpretation of LVAD parameters and recognition of abnormal patterns of flow and pulsatility on the device interrogation are necessary for clinical assessment of the patient. Optimization of pump flow using LVAD parameters and echocardiographic and hemodynamics guidance are reviewed...
July 2018: Critical Care Clinics
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