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https://www.readbyqxmd.com/read/29228289/clinical-practice-guideline-for-physical-therapy-assessment-and-treatment-in-patients-with-nonspecific-neck-pain
#1
Jasper D Bier, Wendy G M Scholten-Peeters, J Bart Staal, Jan Pool, Maurits W van Tulder, Emmylou Beekman, Jesper Knoop, Guus Meerhoff, Arianne P Verhagen
The Royal Dutch Society for Physical Therapy (KNGF) issued a clinical practice guideline for physical therapists that addresses the assessment and treatment of patients with nonspecific neck pain, including cervical radiculopathy, in Dutch primary care. Recommendations were based on a review of published systematic reviews.During the intake, the patient is screened for serious pathologies and corresponding patterns. Patients with cervical radiculopathy can be included or excluded through corresponding signs and symptoms and possibly diagnostic tests (Spurling test, traction/distraction test, and Upper Limb Tension Test)...
December 4, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29228043/novel-systems-for-the-application-of-isolated-tensile-compressive-and-shearing-stimulation-of-distraction-callus-tissue
#2
Nicholaus Meyers, Julian Schülke, Anita Ignatius, Lutz Claes
BACKGROUND: Distraction osteogenesis is a procedure widely used for the correction of large bone defects. However, a high complication rate persists, likely due to insufficient stability during maturation. Numerical fracture healing models predict bone regeneration under different mechanical conditions allowing fixation stiffness optimization. However, most models apply a linear elastic material law inappropriate for the transient stresses/strains present during limb lengthening or segment transport...
2017: PloS One
https://www.readbyqxmd.com/read/29227577/management-of-pain-in-end-stage-renal-disease-patients-short-review
#3
REVIEW
Rupesh Raina, Vinod Krishnappa, Mona Gupta
Pain management in end stage renal disease (ESRD) patients is a complex and challenging task to accomplish, and effective pain and symptom control improves quality of life. Pain is prevalent in more than 50% of hemodialysis patients and up to 75% of these patients are treated ineffectively due to its poor recognition by providers. A good history for PQRST factors and intensity assessment using visual analog scale are the initial steps in the management of pain followed by involvement of palliative care, patient and family counseling, discussion of treatment options, and correction of reversible causes...
December 11, 2017: Hemodialysis International
https://www.readbyqxmd.com/read/29226121/facts-and-fallacies-in-the-debate-on-glyphosate-toxicity
#4
Robin Mesnage, Michael N Antoniou
The safety profile of the herbicide glyphosate and its commercial formulations is controversial. Reviews have been published by individuals who are consultants and employees of companies commercializing glyphosate-based herbicides in support of glyphosate's reapproval by regulatory agencies. These authors conclude that glyphosate is safe at levels below regulatory permissible limits. In contrast, reviews conducted by academic scientists independent of industry report toxic effects below regulatory limits, as well as shortcomings of the current regulatory evaluation of risks associated with glyphosate exposures...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29224729/different-cognitive-complaint-profiles-in-memory-clinic-and-depressive-patients
#5
Lisa Miebach, Steffen Wolfsgruber, Ingo Frommann, Rachel Buckley, Michael Wagner
OBJECTIVE: Cognitive complaints are considered early indicators of incipient Alzheimer's disease (AD) but are very common in geriatric patients, especially in patients with major depressive disorder (MDD). The clinical assessment of cognitive complaints is still poorly operationalized. Recent qualitative research suggests that certain phenomenologic complaint themes may have some specificity for prodromal AD. The aim of the study was to replicate and explore their occurrence in a clinical setting...
November 8, 2017: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29223795/good-distractions-testing-the-effects-of-listening-to-an-audiobook-on-driving-performance-in-simple-and-complex-road-environments
#6
Robert J Nowosielski, Lana M Trick, Ryan Toxopeus
Distracted driving (driving while performing a secondary task) causes many collisions. Most research on distracted driving has focused on operating a cell-phone, but distracted driving can include eating while driving, conversing with passengers or listening to music or audiobooks. Although the research has focused on the deleterious effects of distraction, there may be situations where distraction improves driving performance. Fatigue and boredom are also associated with collision risk and it is possible that secondary tasks can help alleviate the effects of fatigue and boredom...
December 7, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29222797/an-in-vivo-compression-model-of-spinal-cord-injury
#7
Irene Paterniti, Emanuela Esposito, Salvatore Cuzzocrea
Animal spinal cord injury (SCI) models have proven highly useful for investigating the mechanisms involved in the injury process and evaluating the effectiveness of experimental therapeutic interventions. Over the last years, substantial improvements have been made in producing consistent and reproducible animal SCI models. Different SCI models have been developed to address the mechanism of injury, being divided into contusion, compression, distraction, dislocation, transection, or chemical models. The method described here is a mouse compression model of SCI that, in many respects, faithfully reproduces SCI in man...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29222695/the-effects-of-enhanced-attention-and-working-memory-on-smooth-pursuit-eye-movement
#8
Jacob L Stubbs, Sherryse L Corrow, Benjamin Kiang, William J Panenka, Jason J S Barton
It has long been suggested that increasing attentional demands can alter smooth pursuit eye movements, but the precise nature of the changes generated is not clear. Our goal was to examine smooth pursuit with a task that enhanced attention to the target and that increased demands on working memory, without distracting from the target. 15 subjects tracked a target moving around a predictable circular trajectory at a constant tangential velocity. An n-back task with two levels of additional working memory load was integrated into the pursuit target to increase cognitive demands...
December 8, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/29222531/effects-of-aging-on-interference-during-pronoun-resolution
#9
Jana Reifegerste, Claudia Felser
Purpose: The purpose of this study is to investigate the effects of healthy aging on the ability to suppress grammatically illicit antecedents during pronoun resolution. Method: In 2 reading-based acceptability-judgment experiments, younger and older speakers of German read sentences containing an object pronoun and 2 potential antecedent noun phrases, only 1 of which was a grammatically licit antecedent. Using a gender-mismatch paradigm, we compared to what extent younger and older speakers were sensitive to feature (mis)matches between the pronoun and either of the 2 antecedents...
December 8, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29222491/exploring-biased-attention-towards-body-related-stimuli-and-its-relationship-with-body-awareness
#10
Gerardo Salvato, Gabriele De Maio, Gabriella Bottini
Stimuli of great social relevance exogenously capture attention. Here we explored the impact of body-related stimuli on endogenous attention. Additionally, we investigate the influence of internal states on biased attention towards this class of stimuli. Participants were presented with a body, face, or chair cue to hold in memory (Memory task) or to merely attend (Priming task) and, subsequently, they were asked to find a circle in an unrelated visual search task. In the valid condition, the circle was flanked by the cue...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29218508/use-of-huh6-and-other-human-derived-hepatoma-lines-for-the-detection-of-genotoxins-a-new-hope-for-laboratory-animals
#11
Monika Waldherr, Miroslav Mišík, Franziska Ferk, Jana Tomc, Bojana Žegura, Metka Filipič, Wolfgang Mikulits, Sören Mai, Oskar Haas, Wolfgang W Huber, Elisabeth Haslinger, Siegfried Knasmüller
Cell lines which are currently used in genotoxicity tests lack enzymes which activate/detoxify mutagens. Therefore, rodent-derived liver preparations are used which reflect their metabolism in humans only partly; as a consequence misleading results are often obtained. Previous findings suggest that certain liver cell lines express phase I/II enzymes and detect promutagens without activation; however, their use is hampered by different shortcomings. The aim of this study was the identification of a suitable cell line...
December 7, 2017: Archives of Toxicology
https://www.readbyqxmd.com/read/29218500/an-initial-investigation-of-individual-rate-of-play-preferences-and-associations-with-egm-gambling-behavior
#12
Patrick D Worhunsky, Robert D Rogers
Electronic gambling machines (EGMs) show a strong association with gambling problems. The high speed of gaming offered by modern EGMs allows playing numerous games in a short span of time, which is thought to contribute to attentional distraction, increased spending and prolonged play. However, the relationship between EGM speeds and potentially risk-related gambling behavior remains unclear. We introduce a novel approach to investigating the role of gaming speed in EGM gambling behavior by examining 'individual rate-of-play' (I-ROP) during simulated EGM gambling...
December 7, 2017: Journal of Gambling Studies
https://www.readbyqxmd.com/read/29215444/mandibular-reconstruction-by-osteogenic-distraction-due-to-two-different-injuries
#13
Guilherme Dos Santos Trento, José Maurício Dos Santos Nunes Reis, Eduardo Hochuli-Vieira, Valfrido Antônio Pereira-Filho
Varied factors, whether intrinsic or extrinsic, may lead to a decrease in the bone volume of the jaws. Trauma and pathology can be listed as examples of such factors. The aim of this study is to present the osteogenic distraction technique as alternative to augmentation of low mandibular bone volume caused by different etiologies. The first case reports a mandibular marginal resection of ameloblastoma and the second one reports a male patient presenting mandibular fracture sequelae. Both cases were treated according to the osteogenic distraction technique...
December 6, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29214869/the-relationship-between-the-personality-inventory-for-the-dsm-5-pid-5-and-the-psychotic-disorder-in-a-clinical-sample
#14
Tim Bastiaens, Dirk Smits, Marc De Hert, Erik Thys, Hendrik Bryon, Kim Sweers, Teresa Teugels, Joeri Van Looy, Tim Verwerft, Dominique Vanwalleghem, Ludi Van Bouwel, Laurence Claes
Recent studies have successfully investigated the validity of the DSM-5 Alternative Model for Personality Disorders. In a final sample of 174 psychiatric patients, the present study examined the relationship between the Personality Inventory for the DSM-5 (PID-5) and syndromal psychosis. Results showed that patients diagnosed with versus without a psychotic disorder significantly differed on all PID-5 domains except Antagonism. Discriminant function analysis indicated that lower Detachment, lower Negative Affect, lower Disinhibition, and higher Psychoticism best discriminated patients with a psychotic disorder from patients with other psychiatric conditions...
February 1, 2017: Assessment
https://www.readbyqxmd.com/read/29214336/the-efficacy-and-safety-of-early-postoperative-botulinum-toxin-a-injection-for-facial-scars
#15
Seo H Lee, Hyung J Min, Yang W Kim, Young W Cheon
BACKGROUND: Scars widen when the underlying musculature pulls apart suture lines, and scars oriented against relaxed skin tension lines are especially susceptible to these distraction forces. Because botulinum toxin A (BTA) induces complete muscle paralysis, the purpose of the current study was to evaluate the effects of BTA using both observer-dependent qualitative assessments and quantitative measurements to verify its beneficial effects on facial scarring. METHODS: Patients with vertical forehead lacerations, treated by primary closure, were randomly assigned to two groups: one (n = 15) received BTA injections within 5 days of primary closure and the other (n = 15) received no further treatment...
December 6, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29212690/quantifying-the-law-of-diminishing-returns-in-magnetically-controlled-growing-rods
#16
A Ahmad, T Subramanian, P Panteliadis, J Wilson-Macdonald, D A Rothenfluh, C Nnadi
AIMS: Magnetically controlled growing rods (MCGRs) allow non-invasive correction of the spinal deformity in the treatment of early-onset scoliosis. Conventional growing rod systems (CGRS) need repeated surgical distractions: these are associated with the effect of the 'law of diminishing returns'. The primary aim of this study was to quantify this effect in MCGRs over sequential distractions. PATIENTS AND METHODS: A total of 35 patients with a maximum follow-up of 57 months were included in the study...
December 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29208343/single-center-experience-with-intrathecal-administration-of-nusinersen-in-children-with-spinal-muscular-atrophy-type-1
#17
Astrid Pechmann, Thorsten Langer, Sabine Wider, Janbernd Kirschner
BACKGROUND: Spinal muscular atrophy (SMA) is a neuromuscular disorder mainly characterized by proximal muscle weakness. There have been enormous advances in therapeutic development with the possibility to influence the clinical course of the disease. Nusinersen is the first approved drug to treat SMA. It is administered intrathecally and acts as splicing modifier of the SMN2 gene. METHODS: Lumbar punctures were performed using a standardized protocol. To evaluate safety and feasibility of the intrathecal treatment, vital signs and the need for sedation, analgesia or mechanical ventilation during the procedure were monitored...
November 21, 2017: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/29207727/effect-of-cellular-mobile-phone-use-and-cetrizine-on-hand-eye-coordination-and-visual-acuity
#18
Kalpita Ganpat Gawit, Smita Anand Tiwari, Gauri Hari Kasabe, Pradeep Kisanrao Deshpande, Balasaheb Baburao Ghongane
Introduction: Cellular mobile phones are a major cause of distraction especially while driving. The aggressive and inappropriate use of cellular mobile phones has increased the risk of accidents. Similar alerts are available in literature for certain substances and drugs (e.g. second generation anti H1 drug -Cetirizine) which also derange psychomotor performance and parameters of alertness. Aim: This study measured variations in hand-eye coordination and visual acuity due to use of cellular mobile phone in comparison to that of commonly used antihistaminic drug viz...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29204196/delineate-yet-not-dread-anomalous-vertebral-artery-in-pediatric-congenital-atlantoaxial-dislocation-and-basilar-invagination
#19
Pravin Salunke
Introduction: The deformed joints seen in congenital atlantoaxial dislocation (CAAD) are often associated with vascular anomalies. It is important to identify these vascular anomalies and address them appropriately without compromising the manipulation and fusion of C1-C2 joints. The small bones in pediatric age group pose an additional challenge. Materials and Methods: Data of fifty-six children with CAAD operated in the last 4 years was analyzed. A computed tomography angiogram was obtained preoperatively to assess for the course of the third segment of vertebral artery (VA)...
July 2017: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29204129/-maybe-i-will-just-send-a-quick-text%C3%A2-an-examination-of-drivers-distractions-causes-and-potential-interventions
#20
Ole J Johansson, Aslak Fyhri
Many people use cars all over the world. This is, however, not done without risk, as traffic accidents are one of the most common causes of death for adolescents worldwide. The number of deaths has steadily decreased, both worldwide and in Norway. Many of these accidents involve passenger cars and distracted driving. While there are many campaigns to improve safety in traffic, little research has looked at distractions. A recent report has investigated the occurrence of and damage caused by distraction, and one article has looked at what predicts baseline differences in levels of distracted driving...
2017: Frontiers in Psychology
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