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Pleural effusion transudate

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https://www.readbyqxmd.com/read/28215651/behaviour-of-nucleated-cells-in-various-types-of-pleural-effusion
#1
L Ferreiro, T Pereiro, E San José, M E Toubes, J Suárez-Antelo, J M Álvarez Dobaño, F J González Barcala, N Rodríguez Núñez, A Lama, L Valdés
INTRODUCTION: To know the behavior of cellular components of pleural fluid can help focus the differential diagnosis of a pleural effusion. Our objective was to assess their composition in different types of pleural effusions and assess whether it provides relevant clinical information. PATIENTS AND METHODS: Observational, cross-sectional and retrospective study in which the cellular components of pleural effusions of different etiology were analyzed. Pleural effusions were classified as neutrophilic, lymphocytic (≥50% of each one of them), eosinophilic (≥10%) or mesothelial (>5%) and were grouped into six diagnostic categories RESULTS: 1...
February 16, 2017: Revista Clínica Española
https://www.readbyqxmd.com/read/28209662/the-impact-of-between-analytical-platform-variability-on-the-classification-of-pleural-effusions-into-exudate-or-transudate-using-light-s-criteria
#2
Michael P Cornes, Andrew J Chadburn, Claire Thomas, Catherine Darby, Rachel Webster, Clare Ford, Rousseau Gama
BACKGROUND: Light's criteria are ratios of pleural fluid to serum total protein (TP), pleural fluid to serum lactate dehydrogenase (LDH) and pleural fluid LDH to the upper reference limit for serum LDH. They are used to classify pleural effusions into an exudate or transudate when pleural fluid protein is 25-35 g/L. We evaluated the impact of between analytical platforms on the classification of pleural effusions using Light's criteria. METHODS: Light's criteria were used to classify pleural effusions with fluid TP between 25 and 35 g/L into exudate and transudate...
February 16, 2017: Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28203412/predictive-models-of-malignant-transudative-pleural-effusions
#3
Lucía Ferreiro, Francisco Gude, María E Toubes, Adriana Lama, Juan Suárez-Antelo, Esther San-José, Francisco Javier González-Barcala, Antonio Golpe, José M Álvarez-Dobaño, Carlos Rábade, Nuria Rodríguez-Núñez, Carla Díaz-Louzao, Luis Valdés
BACKGROUND: There are no firm recommendations when cytology should be performed in pleural transudates, since some malignant pleural effusions (MPEs) behave biochemically as transudates. The objective was to assess when would be justified to perform cytology on pleural transudates. METHODS: Consecutive patients with transudative pleural effusion (PE) were enrolled and divided in two groups: malignant and non-MPE. Logistic regression analysis was used to estimate the probability of malignancy...
January 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28191357/metastatic-invasive-lobular-breast-cancer-presenting-clinically-with-esophageal-dysphagia
#4
Lilit Karapetyan, Heather Laird-Fick, Reuben Cuison
Background. Intra-abdominal metastases of invasive lobular breast cancer (ILBC) may be insidious. We report a case of metastatic ILBC that presented with dysphagia within weeks of a negative mammogram and before the development of intra-abdominal symptoms. Case. A 70-year-old female developed esophageal dysphagia. She underwent EGD which showed a short segment of stricture of the distal esophagus without significant mucosal changes. Biopsy was unremarkable and patient underwent lower esophageal sphincter (LES) dilation...
2017: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/28140518/metabonomics-by-proton-nuclear-magnetic-resonance-in-human-pleural-effusions-a-route-to-discriminate-between-benign-and-malignant-pleural-effusions-and-to-target-small-molecules-as-potential-cancer-biomarkers
#5
Lucio Zennaro, Paola Vanzani, Lorenzo Nicolè, Rocco Cappellesso, Ambrogio Fassina
BACKGROUND: Cytopathology is a noninvasive and cost-effective method for detecting cancer cells in pleural effusions (PEs), although in many cases, the diagnostic performance is hindered by the paucity of significant cells or the lack of clear morphological criteria. This study presents the results of an omics approach to improving the diagnostic performance of PE cytology. METHODS: Metabolic profiling with proton nuclear magnetic resonance ((1) H-NMR) was performed for 92 PEs (44 malignant cases of 8 different cancers and 48 benign cases of 7 nonneoplastic conditions)...
January 31, 2017: Cancer
https://www.readbyqxmd.com/read/28121949/reactive-oxygen-species-modulator-1-romo1-as-a-novel-diagnostic-marker-for-lung-cancer-related-malignant-effusion
#6
Seung Hyeun Lee, Myung Jae Park, Sue In Choi, Eun Joo Lee, Sang Yeub Lee, Kwang Ho In
Reactive oxygen species modulator 1 (Romo1) is a novel protein that plays an important role in intracellular reactive oxygen species generation. Recently, Romo1 has been suggested to have diagnostic and prognostic potential in lung cancer. However, there is no data on the diagnostic value of Romo1 level in malignant pleural effusion. We evaluated the clinical usefulness of Romo1 in pleural fluid for the diagnosis of malignant effusion in lung cancer patients. Pleural fluid Romo1 level was measured using enzyme-linked immunosorbent assay and compared between lung cancer-associated malignant effusion (n = 53; 29 adenocarcinomas and 24 squamous cell carcinomas) and benign pleural effusions (n = 91; 31 tuberculous pleurisy, 30 parapneumonic effusion, and 30 transudate)...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28025056/non-malignant-pleural-effusions-nmpe-a-prospective-study-of-356-consecutive-unselected-patients
#7
Steven P Walker, Anna J Morley, Louise Stadon, Duneesha De Fonseka, David A Arnold, Andrew Rl Medford, Nick A Maskell
BACKGROUND: Pleural effusions secondary to a non-malignant aetiology can represent significant morbidity and mortality. These non-malignant pleural effusions (NMPE) are common, with congestive heart failure (CHF) representing the leading cause. Despite this, there is limited data on mortality risk and the factors which influence them. METHODS: We recruited 782 consecutive patients presenting to a pleural service, between 03/2008 and 03/2015, with an undiagnosed pleural effusion...
December 23, 2016: Chest
https://www.readbyqxmd.com/read/27981931/pleural-effusion-developing-in-two-patients-on-continuous-ambulatory-peritoneal-dialysis
#8
Muhammad Asim
Two patients with end-stage-renal-disease on continuous ambulatory peritoneal dialysis (CAPD) presented with pleural effusions. The aspirated fluid was categorised as transudate, based on alkaline pH, low protein and lactic dehydrogenase level. A striking feature of the pleural fluid was, its very high glucose content that resulted from translocation of dextrose containing peritoneal dialysate into the pleural space via a pleuroperitoneal connection. One patient was transferred to hemodialysis, which led to complete resolution of pleural effusion...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27916209/concordant-and-discordant-exudates-and-their-effect-on-the-accuracy-of-light-s-criteria-to-diagnose-exudative-pleural-effusions
#9
Lucía Ferreiro, Rolando Sánchez-Sánchez, Luis Valdés, Carlos E Kummerfeldt, John T Huggins
INTRODUCTION: To describe the incidence of discordant exudate (DE) effusions, their underlying etiologies and their effect on the accuracy of the Light's criteria to diagnose exudate effusions. METHODS: A retrospective review of pleural fluid analysis (PFA) from a cohort of patients with pleural effusion (PE) who underwent thoracentesis. PEs were defined as exudative based on the Light's criteria. The effusions were further classified in concordant or DE. RESULTS: From 847 PE samples, 611 (72...
December 2016: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/27904546/cured-transudative-pleural-effusion-a-case-report
#10
Mohsen Shafipoor, Arda Kiani, Kambiz Sheikhy, Atefeh Abedini, Majid Golestani Eraghi
Echinococcosis or hydatid disease is a helminthic infection caused by larvae of tapeworm Echinococcus granulosus. While the cysts can involve all organs, liver is the most common site of infection and the lungs are the second most commonly involved organ in young adults. In addition to endemic areas its incidence is growing all around the world due to the ease of transcontinental travel. Disease presentation varies and usually is due to mass effect or dysfunction of the involved organ and surgical resection is the recommended treatment...
2016: Tanaffos
https://www.readbyqxmd.com/read/27851542/1907-a-rare-case-of-low-ph-transudative-pleural-effusion-in-a-critically-ill-patient
#11
Viral Patel, Umair Tariq, Wael Nasser
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27805531/postoperative-pleural-effusions-after-orthotopic-heart-transplant-cause-clinical-manifestations-and-course
#12
Gaye Ulubay, Elif Küpeli, Balam Er Dedekargınoğlu, Şerife Savaş Bozbaş, Mahal Alekberov, Özlem Salman Sever, Atilla Sezgin
OBJECTIVES: Postoperative pleural effusions are common in patients who undergo cardiac surgery and orthotopic heart transplant. Postoperative pleural effusions may also occur as postcardiac injury syndrome. Most of these effusions are nonspecific and develop as a harmless complication of the surgical procedure itself and generally have a benign course. Here, we investigated the cause and clinical and laboratory features of postoperative early and late pleural effusions in orthotopic heart transplant patients...
2016: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/27727893/role-of-pleural-fluid-cholesterol-in-differentiating-exudative-from-transudative-pleural-effusions
#13
Nanda B C, Mohapatra Bn, Majhi Cd
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27677622/profile-of-metalloproteinases-and-their-association-with-inflammatory-markers-in-pleural-effusions
#14
Lisete Ribeiro Teixeira, Murilo B Dias, Roberta K B Sales, Leila Antonangelo, Vanessa A Alvarenga, Juliana Puka, Evaldo Marchi, Milena Marques Pagliarelli Acencio
BACKGROUND: Matrix metalloproteinases (MMPs) are responsible for the breakdown of the extracellular matrix and play an important role in the inflammatory processes of pleural exudates. The imbalance between MMPs and their inhibitors (TIMPs) is present in various pathological processes. OBJECTIVE: To evaluate the profile of MMPs and TIMPs in pleural effusions of different etiologies correlated with inflammatory markers. METHODS: The patients with pleural effusion due to tuberculosis (TB), cancer (CA) or transudate were prospectively evaluated...
September 27, 2016: Lung
https://www.readbyqxmd.com/read/27627084/-the-differential-diagnosis-of-pleural-effusions
#15
Miloslav Marel, Libor Fila, Michaela Červená
UNLABELLED: The problems of pleural effusions are connected with many areas of medicine. The problem affects approx. 0.5 % of the population every year. The paper summarizes pathophysiological data relating to the emergence of effusions, their epidemiology, description of particular types of effusions and possibilities of treatment. More attention is paid to the differential diagnosis and therapy for malign pleural effusions. KEY WORDS: diagnostics - exudate - treatment - pleura - transudate...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27523894/-interleukin-20-and-interleukin-22-in-pleural-effusion
#16
T Z Cao, R H Du, Z Lian, W Jin, M Qiu
OBJECTIVE: To investigate the concentrations and clinical significance of interleukin (IL)-20 and IL-22 in pleural effusion with various etiologies. METHODS: Pleural effusion (PE) and corresponding serum samples were obtained from 88 patients from Wuhan Tuberculosis Prevention and Control Institute from June 2011 to June 2013. There were 27 cases with malignant pleural effusion, 24 with tuberculous pleural effusion, 17 with bacterial pleural effusion and 20 with transudativeeffusion...
August 2016: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/27520469/chronic-eosinophilic-pneumonia-presenting-with-ipsilateral-pleural-effusion-a-case-report
#17
Narin Sriratanaviriyakul, Hanh H La, Timothy E Albertson
BACKGROUND: Chronic eosinophilic pneumonia is a rare idiopathic interstitial lung disease. The nearly pathognomonic radiographic finding is the peripheral distribution of alveolar opacities. Pleural effusions are rarely seen. We report a case of chronic eosinophilic pneumonia with transudative eosinophilic pleural effusion. CASE PRESENTATION: A 57-year-old Hispanic woman, a nonsmoker with a history of controlled asthma, presented to the hospital with unresolving pneumonia despite three rounds of antibiotics over a 2-month period...
August 12, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27502152/25-hydroxyvitamin-d-in-malignant-pleural-disease-a-prospective-cohort-study
#18
Marios Panagiotou, Andriana I Papaioannou, Konstantinos Kostikas, Anna Takou, Maria Paraskeva, Alexandros Kalkanis, Filia Diamantea, Emmanuil Kastanakis, George Maropoulos, Vasiliki Filaditaki, Napoleon Karagianidis
INTRODUCTION: Growing evidence suggests a role of vitamin D in various cancers but the significance of vitamin D in malignant pleural disease remains unexplored. We sought to investigate the concentration and diagnostic role of 25-hydroxyvitamin D (25(OH)D) in malignant pleural effusions. MATERIALS AND METHODS: Prospective study of consecutive treatment-naïve patients with a new diagnosis of pleural effusion. RESULTS: Seventy-eight patients were studied, 45 of whom had malignant pleural effusions...
August 9, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27437279/urinothorax-a-rare-postoperative-complication-of-adrenalectomy
#19
Deepa Kalikavil Puthenveedu, Natarajan Manickam, Arul Rajamurugan Ponniah Subramanian, Palani Kumar Baluchamy
Urinothorax is a rare condition defined by the presence of urine in the pleural cavity. Here we report a case of a patient with left sided transudative pleural effusion which developed following left adrenalectomy with perisplenic collection. The pleural fluid to serum creatinine ratio was found to be greater than one which confirmed the diagnosis. The objective of this case report was to describe this rare case and to alert the physicians to include urinothorax in their differential diagnosis of transudative pleural effusion especially following abdominal surgery...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27419065/spontaneous-bacterial-empyema-in-a-non-cirrhotic-end-stage-renal-disease-patient-with-immunosuppression
#20
Dennis Lourdusamy, Lubna B Munshi, Sherif Ali Eltawansy
Spontaneous Bacterial Empyema (SBEM) denotes infection of the pleural fluid in the absence of pneumonia. Almost all cases of SBEM in literature are described in a background of ascites secondary to cirrhosis. Contiguous spread of the infected ascitic fluid through defects in the diaphragm is the most likely mechanism of SBEM. Most of these cases are transudative in nature and are managed with antibiotics. Literature on SBEM in the absence of cirrhosis or ascites is very limited so far. We describe a 59 year old female with ESRD status post renal transplant, on chronic immunosuppression for renal allograft rejection who was admitted with pleuritic chest pain that turned to be secondary to right sided pleural effusion...
2016: Respiratory Medicine Case Reports
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