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https://www.readbyqxmd.com/read/29150861/cost-effectiveness-of-the-psycho-educational-blended-group-and-online-intervention-hypoaware-compared-with-usual-care-for-people-with-type-1-and-insulin-treated-type-2-diabetes-with-problematic-hypoglycaemia-analyses-of-a-cluster-randomized-controlled-trial
#1
M de Wit, S M P A Rondags, M W van Tulder, F J Snoek, J E Bosmans
AIMS: To evaluate the cost-effectiveness of HypoAware, a blended (group and online) psycho-educational intervention based on the evidence-based Blood Glucose Awareness Training, in comparison with usual care in people with Type 1 and Type 2 diabetes with a high risk of severe hypoglycaemia. METHODS: We performed an economic evaluation, from a societal and healthcare perspective, that used data from a 6-month, multicentre, cluster-randomized controlled trial (n=137)...
November 18, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29148955/experience-of-tubo-ovarian-abscess-a-retrospective-clinical-analysis-of-318-patients-in-a-single-tertiary-center-in-middle-turkey
#2
Zeynep Ozturk Inal, Hasan Ali Inal, Umit Gorkem
BACKGROUND: The objective was to identify the clinical and laboratory parameters, ultrasonographic (USG) morphology, and to predict surgical treatment for patients with tubo-ovarian abscess (TOA). PATIENTS AND METHODS: Data for a total of 318 patients with a diagnosis of TOA between January 2005 and December 2016 were analyzed retrospectively at a referral center in Turkey. Patients requiring surgical treatment were compared with those who did not with respect to demographic characteristics and clinical, USG, and laboratory findings...
November 17, 2017: Surgical Infections
https://www.readbyqxmd.com/read/29146645/logistic-regression-analysis-of-factors-influencing-the-effectiveness-of-intensive-sound-masking-therapy-in-patients-with-tinnitus
#3
Yuexin Cai, Qian Zhou, Haidi Yang, Jiajia Jiang, Fei Zhao, Xiayin Huang, Hanjie Mo, Xiaoting Chen, Hao Xiong, Suijun Chen, Xueyuan Zhang, Yiqing Zheng
OBJECTIVES: To investigate factors influencing the effectiveness of intensive sound masking therapy on tinnitus using logistic regression analysis. DESIGN: The study used a retrospective cross-section analysis. PARTICIPANTS: 102 patients with tinnitus were recruited at the Sun Yat-sen Memorial Hospital of Sun Yat-sen University, China. INTERVENTION: Intensive sound masking therapy was used as an intervention approach for patients with tinnitus...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29146622/refusal-of-treatment-of-childhood-cancer-a-systematic-review
#4
REVIEW
Amy E Caruso Brown, Amy R Slutzky
CONTEXT: Refusal of treatment for childhood cancer engenders much discussion. No systematic study of this phenomenon exists in countries where access to treatment is readily available. OBJECTIVE: To identify and describe all published cases of treatment refusal for childhood cancer in the contemporary era. DATA SOURCES: We searched PubMed, Cumulative Index to Nursing and Allied Health Literature, Scopus, LexisNexis Academic, personal database, and secondary bibliographies...
November 16, 2017: Pediatrics
https://www.readbyqxmd.com/read/29146532/potential-u-s-population-impact-of-the-2017-american-college-of-cardiology-american-heart-association-high-blood-pressure-guideline
#5
Paul Muntner, Robert M Carey, Samuel Gidding, Daniel W Jones, Sandra J Taler, Jackson T Wright, Paul K Whelton
BACKGROUND: The 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults provides recommendations for the definition of hypertension, systolic and diastolic blood pressure (BP) thresholds for initiation of antihypertensive medication and BP target goals. OBJECTIVE: Determine the prevalence of hypertension, implications of recommendations for antihypertensive medication and prevalence of BP above the treatment goal among US adults using criteria from the 2017 ACC/AHA and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7) guidelines...
November 6, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29140929/tactile-acuity-dys-function-in-acute-nociceptive-low-back-pain-a-doubleblind-experiment
#6
Wacław M Adamczyk, Oskar Saulicz, Edward Saulicz, Kerstin Luedtke
Research shows that chronic pain is related to cortical alterations that can be reflected in reduced tactile acuity, but whether acute pain perception influences tactile acuity has not been tested. Considering the biological role of nociception, it was hypothesized that nociceptive pain will lead to a rapid improvement in tactile acuity and that this effect is correlated with pain intensity and pain distribution. In this randomised double-blind controlled experiment (trial no. NCT03021278), healthy participants were exposed to one of three experimental conditions: acute, nociceptive low back pain induced by saline injection, a sham-injection (without piercing the skin) potentially inducing nocebo pain, or no intervention...
November 13, 2017: Pain
https://www.readbyqxmd.com/read/29140616/comparisons-of-agricultural-seating-for-paraplegia
#7
Carla Sue Wilhite, William E Field, Mark Jaramillo, Kevin Sullivan
People with spinal cord injury/paraplegia are operating agricultural machinery despite the lack of research evidence to support seating interventions. These operators represent a vulnerable population in the agricultural workforce, and information to support their health in the workplace is urgently warranted. This research compared a group of subjects with paraplegia on different intervention cushion conditions during a simulated tractor driving task. Numerical data acquired from a pressure-mapping instrument were explored for statistical relationships within a small cohort of people with paraplegia participating in a feasibility study that was previously reported for clinical results...
January 26, 2017: Journal of Agricultural Safety and Health
https://www.readbyqxmd.com/read/29139149/under-recognized-entity-of-the-transient-rise-in-the-atrial-capture-threshold-early-after-dual-chamber-pacemaker-implantation
#8
Yoshiko Uehara, Kentaro Yoshida, Akira Kimata, Kojiro Ogawa, Daisuke Abe, Yasuaki Tsumagari, Hidekazu Tsuneoka, Yoshiaki Yui, Yoko Ito, Mari Ebine, Noriyuki Takeyasu, Kazutaka Aonuma, Akihiko Nogami
BACKGROUND: Steroid-eluting pacemaker leads suppress acute rises in pacing threshold by preventing inflammatory processes. However, we occasionally encounter not persistent but transient rise in the atrial capture threshold (TRACT) early after pacemaker implantation. We believe that this phenomenon is under-recognized in clinical practice and may potentially lead to unnecessary re-intervention. We aimed to clarify the prevalence, predictors, and possible mechanisms of TRACT. METHODS AND RESULTS: We reviewed clinical records from 239 consecutive patients who underwent dual-chamber pacemaker implantation for sick sinus syndrome (SSS) (N = 102) or atrioventricular block (AVB) (N = 137)...
November 15, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29138584/repeated-intermittent-ulipristal-acetate-in-the-treatment-of-uterine-fibroids-a-cost-effectiveness-analysis
#9
Kirk Geale, Ertan Saridogan, Matthieu Lehmann, Pablo Arriagada, Marcus Hultberg, Martin Henriksson
There are limited treatment options available for women with moderate to severe symptoms of uterine fibroids (UFs) who wish to avoid surgery. For these women, treatment with standard pharmaceuticals such as contraceptives is often insufficient to relieve symptoms, and patients may require surgery despite their wish to avoid it. Clinical trials demonstrate that ulipristal acetate 5 mg (UPA) is an effective treatment for this patient group, but its cost-effectiveness has not been assessed in this population. A decision-analytic model was developed to simulate a cohort of patients in this population under treatment with UPA followed by surgery as needed compared to treatment with iron and non-steroidal anti-inflammatory drug (NSAID) followed by surgery as needed (best supportive care, BSC)...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/29136014/treatment-guidelines-and-early-loss-from-care-for-people-living-with-hiv-in-cape-town-south-africa-a-retrospective-cohort-study
#10
Ingrid T Katz, Richard Kaplan, Garrett Fitzmaurice, Dominick Leone, David R Bangsberg, Linda-Gail Bekker, Catherine Orrell
BACKGROUND: South Africa has undergone multiple expansions in antiretroviral therapy (ART) eligibility from an initial CD4+ threshold of ≤200 cells/μl to providing ART for all people living with HIV (PLWH) as of September 2016. We evaluated the association of programmatic changes in ART eligibility with loss from care, both prior to ART initiation and within the first 16 weeks of starting treatment, during a period of programmatic expansion to ART treatment at CD4+ ≤ 350 cells/μl...
November 2017: PLoS Medicine
https://www.readbyqxmd.com/read/29135878/single-sided-deafness-impact-of-cochlear-implantation-on-speech-perception-in-complex-noise-and-on-auditory-localization-accuracy
#11
Julia Döge, Uwe Baumann, Tobias Weissgerber, Tobias Rader
OBJECTIVE: To assess auditory localization accuracy and speech reception threshold (SRT) in complex noise conditions in adult patients with acquired single-sided deafness, after intervention with a cochlear implant (CI) in the deaf ear. STUDY DESIGN: Nonrandomized, open, prospective patient series. SETTING: Tertiary referral university hospital. PATIENTS: Eleven patients with late-onset single-sided deafness (SSD) and normal hearing in the unaffected ear, who received a CI...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29135864/patterns-of-extended-high-frequency-hearing-loss-following-stapes-surgery
#12
Melissa J Babbage, Greg A O'Beirne, Michael J Bergin, Philip A Bird
OBJECTIVE: Thresholds in the extended high-frequency (EHF) range (> 8 kHz) often worsen after otherwise successful stapedectomy. The aims of this study were to document the prevalence of hearing loss from 0.25 to 16 kHz after stapedectomy and the relative rates of transient and permanent EHF hearing loss. STUDY DESIGN: Prospective, observational, longitudinal. SETTING: Tertiary referral center. PATIENTS: Thirty-nine patients who underwent 44 primary or revision stapes surgeries...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29135576/assisted-partner-notification-services-are-cost-effective-for-decreasing-hiv-burden-in-western-kenya-a-mathematical-modeling-analysis
#13
Monisha Sharma, Jennifer A Smith, Carey Farquhar, Roger Ying, Peter Cherutich, Matthew Golden, Beatrice Wamuti, David Bukusi, Hans Spiegel, Ruanne V Barnabas
BACKGROUND: Assisted partner services (aPS) or provider notification for sexual partners of persons diagnosed HIV-positive can increase HIV testing and linkage in sub-Saharan Africa (SSA) and is a high yield strategy to identify HIV-positive persons. However, its cost-effectiveness is not well-evaluated. METHODS: Using effectiveness and cost data from an aPS trial in Kenya, we parameterized an individual-based, dynamic HIV transmission model. We estimated costs for both a program scenario and a task-shifting scenario using community health workers to conduct the intervention...
November 10, 2017: AIDS
https://www.readbyqxmd.com/read/29135458/immediate-effects-of-osteopathic-treatment-versus-therapeutic-exercise-on-patients-with-chronic-cervical-pain
#14
Xabier Galindez-Ibarbengoetxea, Igor Setuain, Robinson Ramírez-Velez, Lars L Andersen, Miriam González-Izal, Andoni Jauregi, Mikel Izquierdo
Context • Alternatives to medication for immediate pain relief are needed because long-term use of pain medication has been associated with adverse effects. High-velocity, low-amplitude (HVLA) manipulation techniques (MTs) and craniocervical flexion (CCF) exercises have been frequently used in the management of chronic cervical pain. Objective • The study intended to compare the immediate effects on pain of a treatment using HVLA manipulation versus one using a CCF exercise protocol. Design • The research team designed a single-blinded, randomized clinical trial...
November 14, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29134067/modelling-the-role-of-correctional-services-on-gangs-insights-through-a-mathematical-model
#15
F Nyabadza, C P Ogbogbo, J Mushanyu
Research has shown that gang membership increases the chances of offending, antisocial behaviour and drug use. Gang membership should be acknowledged as part of crime prevention and policy designs, and when developing interventions and preventative programmes. Correctional services are designed to rehabilitate convicted offenders. We formulate a deterministic mathematical model using nonlinear ordinary differential equations to investigate the role of correctional services on the dynamics of gangs. The recruitment into gang membership is assumed to happen through an imitation process...
October 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/29133599/potential-u-s-population-impact-of-the-2017-american-college-of-cardiology-american-heart-association-high-blood-pressure-guideline
#16
Paul Muntner, Robert M Carey, Samuel Gidding, Daniel W Jones, Sandra J Taler, Jackson T Wright, Paul K Whelton
Background -The 2017 American College of Cardiology/American Heart Association (ACC/AHA) Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults provides recommendations for the definition of hypertension, systolic and diastolic blood pressure (BP) thresholds for initiation of antihypertensive medication and BP target goals. The objective of this study was to determine the prevalence of hypertension, implications of recommendations for antihypertensive medication and prevalence of BP above the treatment goal among US adults using criteria from the 2017 ACC/AHA and the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7) guidelines...
November 13, 2017: Circulation
https://www.readbyqxmd.com/read/29132733/enhanced-nutrient-supply-to-very-low-birth-weight-infants-is-associated-with-higher-blood-amino-acid-concentrations-and-improved-growth
#17
Kenneth Strømmen, Alexander Haag, Sissel J Moltu, Marit B Veierød, Elin W Blakstad, Britt Nakstad, Astrid N Almaas, Kristin Brække, Arild E Rønnestad, Hannelore Daniel, Christian A Drevon, Per O Iversen
BACKGROUND & AIMS: Customized nutrient supply is vital to ensure optimal growth among very low birth weight infants (birth weight < 1500 g). The supply of amino acids is especially important due to their impact on protein synthesis and growth. The objectives of this study were to evaluate the impact of enhanced nutrition on growth, blood concentrations of amino acids, and explore possible associations between amino acid concentrations and common neonatal morbidities. We hypothesized higher amino acids levels and growth velocity among infants on enhanced nutrient supply...
April 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29130382/less-affected-hand-function-in-children-with-hemiparetic-unilateral-cerebral-palsy-a-comparison-study-with-typically-developing-peers
#18
Tonya L Rich, Jeremiah S Menk, Kyle D Rudser, Timothy Feyma, Bernadette T Gillick
BACKGROUND: Neurorehabilitation interventions in children with unilateral cerebral palsy (UCP) target motor abilities in daily life yet deficits in hand skills persist. Limitations in the less-affected hand may affect overall bimanual hand skills. OBJECTIVE: To compare hand function, by timed motor performance on the Jebsen-Taylor Test of Hand Function (JTTHF) and grip strength of children with UCP to children with typical development (CTD), aged 8 to 18 years old...
November 1, 2017: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29130072/prediction-of-chronic-kidney-disease-stage-3-by-ckd273-a-urinary-proteomic-biomarker
#19
Claudia Pontillo, Zhen-Yu Zhang, Joost P Schanstra, Lotte Jacobs, Petra Zürbig, Lutgarde Thijs, Adela Ramírez-Torres, Hiddo J L Heerspink, Morten Lindhardt, Ronald Klein, Trevor Orchard, Massimo Porta, Rudolf W Bilous, Nishi Charturvedi, Peter Rossing, Antonia Vlahou, Eva Schepers, Griet Glorieux, William Mullen, Christian Delles, Peter Verhamme, Raymond Vanholder, Jan A Staessen, Harald Mischak, Joachim Jankowski
Introduction: CKD273 is a urinary biomarker, which in advanced chronic kidney disease predicts further deterioration. We investigated whether CKD273 can also predict a decline of estimated glomerular filtration rate (eGFR) to <60 ml/min per 1.73 m(2). Methods: In analyses of 2087 individuals from 6 cohorts (46.4% women; 73.5% with diabetes; mean age, 46.1 years; eGFR ≥ 60 ml/min per 1.73 m(2), 100%; urinary albumin excretion rate [UAE] ≥20 μg/min, 6.2%), we accounted for cohort, sex, age, mean arterial pressure, diabetes, and eGFR at baseline and expressed associations per 1-SD increment in urinary biomarkers...
November 2017: KI Reports
https://www.readbyqxmd.com/read/29129184/identifying-attributes-of-care-that-may-improve-cost-effectiveness-in-the-youth-mental-health-service-system
#20
Matthew P Hamilton, Sarah E Hetrick, Cathrine Mihalopoulos, David Baker, Vivienne Browne, Andrew M Chanen, Kerryn Pennell, Rosemary Purcell, Heather Stavely, Patrick D McGorry
OBJECTIVE: To identify attributes of youth mental health care for which there is evidence of potential cost-effectiveness. STUDY DESIGN: We performed a literature review of economic evaluations that examined both costs and outcomes for attributes of youth mental health care other than pharmacological or individual psychological therapies for full-threshold disorders. DATA SOURCES: We searched the United Kingdom National Health Service Economic Evaluations Database for evaluations published to the end of 2014; and MEDLINE, Google Scholar and the citation lists of relevant publications for peer-reviewed studies published in English since 1997...
November 20, 2017: Medical Journal of Australia
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