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https://www.readbyqxmd.com/read/29779215/hypocomplementemic-urticarial-vasculitis-occurring-in-a-patient-with-relapsing-polychondritis
#1
Asma Raboudi, Noureddine Litaiem, Meriem Jones, Faten Zeglaoui
No abstract text is available yet for this article.
May 20, 2018: International Journal of Dermatology
https://www.readbyqxmd.com/read/29760256/red-eared-zebra-diagnosis-case-of-relapsing-polychondritis
#2
Karen K Leung, Shakibeh Edani
No abstract text is available yet for this article.
May 2018: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29719184/relapsing-polychondritis
#3
Jen Haslag-Minoff, Hariharan Regunath
New England Journal of Medicine, Volume 378, Issue 18, Page 1715-1715, May 2018.
May 3, 2018: New England Journal of Medicine
https://www.readbyqxmd.com/read/29718381/relapsing-polychondritis-a-diagnosis-not-to-be-missed
#4
Evangelia Zampeli, Haralampos M Moutsopoulos
No abstract text is available yet for this article.
April 30, 2018: Rheumatology
https://www.readbyqxmd.com/read/29715182/remission-of-relapsing-polychondritis-after-successful-treatment-of-myelodysplastic-syndrome-with-azacitidine-a-case-and-review-of-the-literature
#5
Abdulsamet Erden, Emre Bilgin, Levent Kılıç, Alper Sarı, Berkan Armağan, Yahya Büyükaşık, Umut Kalyoncu
BACKGROUND: Relapsing polychondritis (RP) is a rare autoimmune disorder, and myelodysplastic syndrome (MDS) is accompanied by RP at variable rates. Herein, we report a case with RP and MDS who responded dramatically to 5-azacitidine for MDS. CASE PRESENTATION: With conventional immunosuppressive treatment, our patient had several episodes of different side effects, including infections. With the diagnosis of MDS and initiation of azacitidine treatment, all the manifestations of RP disappeared, and remission was achieved for MDS...
May 1, 2018: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/29699514/pleocytosis-in-a-patient-with-relapsing-polychondritis-accompanied-by-meningoencephalitis-a-case-report
#6
Jie Cao, Min Zhang
BACKGROUND: Relapsing polychondritis (RP) is an uncommon immune-related disease with unknown causes. It is characterized by inflammation of cartilaginous or non-cartilaginous structures, such as the ears, nose, respiratory tract, eyes, and joints. Neurological involvement is rare in RP. CASE PRESENTATION: We report a case of pleocytosis in a 64-year-old man diagnosed as having RP with meningoencephalitis. The patient's condition markedly improved following methylprednisolone treatment...
April 25, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29651889/how-to-conduct-research-of-rare-autoimmune-diseases
#7
Chikashi Terao
Rare autoimmune diseases are difficult to conduct researches in spite of present era with advanced scientific progress. Research using genetic approach is a promising way since genetic findings implicate causality of diseases. Still, there are multiple obstacles preventing genetic studies of rare diseases. Here, we list up the problems and propose solutions for them with detailed examples. The biggest problem is that it is difficult to collect a substantial number of DNA samples from patients with rare diseases...
April 13, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29535124/efficacy-and-safety-of-biologics-in-relapsing-polychondritis-a-french-national-multicentre-study
#8
Guillaume Moulis, Grégory Pugnet, Nathalie Costedoat-Chalumeau, Alexis Mathian, Gaëlle Leroux, Jonathan Boutémy, Olivier Espitia, Laurence Bouillet, Sabine Berthier, Jean-Baptiste Gaultier, Pierre-Yves Jeandel, Amadou Konaté, Arsène Mékinian, Elisabeth Solau-Gervais, Benjamin Terrier, Daniel Wendling, Fanny Andry, Camille Garnier, Pascal Cathébras, Laurent Arnaud, Aurore Palmaro, Patrice Cacoub, Zahir Amoura, Jean-Charles Piette, Philippe Arlet, Maryse Lapeyre-Mestre, Laurent Sailler
OBJECTIVES: To assess the efficacy and the safety of biologics in a cohort of patients with relapsing polychondritis (RP). METHODS: We conducted a French multicentre retrospective cohort study including patients treated with biologics for RP. Efficacy outcomes were clinical response (partial or complete) and complete response during the first 6 months of exposure, plus daily corticosteroid dose at 6 months. Other outcomes were adverse drug reactions (ADRs), persistence of biologics and factors associated with a response...
March 13, 2018: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/29503950/surgical-interventions-for-late-ocular-complications-of-relapsing-polychondritis
#9
Yuan He, Huifeng Liu, Zhi Ji, Binliang Zhu
Purpose: To report a case of surgical interventions for a patient with relapsing polychondritis who presented with late ocular complications. Observations: A 44-year-old male was diagnosed to have relapsing polychondritis on the basis of recurrent acute auricular chondritis, deformity of the ear, saddle nose deformity and painful nasal chondritis, acute ocular inflammation with conjunctivitis, episcleritis and keratouveitis, laryngotracheal chondritis, erythema nodosum in the skin, a history of polyarthritis, and abnormal blood examination findings...
April 2017: American Journal of Ophthalmology Case Reports
https://www.readbyqxmd.com/read/29392060/three-cases-of-relapsing-polycondritis-with-isolated-laryngotracheal-stenosis
#10
Hamdi Taşlı, Hakan Birkent, Mustafa Gerek
Relapsing polychondritis (RP) is a rare autoimmune and inflammatory disease, particularly characterized by recurrent inflammation of the hyaline cartilage. Laryngotracheal involvement in RP is the most serious complication that is observed in 50% of the patients and may lead to a life-threatening condition. The most common cause of death is laryngotracheal stenosis associated with lung infections or severe respiratory insufficiency that may be observed in 10%-50% of the patients. In this study, three RP patients comprising a child with isolated laryngotracheal stenosis have been presented...
June 2017: Turkish Archives of Otorhinolaryngology
https://www.readbyqxmd.com/read/29391837/refractory-relapsing-polychondritis-challenges-and-solutions
#11
REVIEW
Fernando Kemta Lekpa, Xavier Chevalier
Relapsing polychondritis is a severe systemic immune-mediated disease characterized by an episodic and progressive inflammatory condition with progressive destruction of cartilaginous structures. This disease has for nearly a century kept secrets not yet explained. The real incidence and prevalence of this rare disease are unknown. The multiple clinical presentations and episodic nature of relapsing polychondritis cause a significant diagnosis delay. No guidelines for the management of patients with relapsing polychondritis have been validated to date...
2018: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/29390537/anca-positive-relapsing-polychondritis-graves-disease-and-suspected-moyamoya-disease-a-case-report
#12
Yi-Yi Xuan, Tian-Fang Li, Lei Zhang, Sheng-Yun Liu
RATIOINALE: Relapsing polychondritis (RP) is a rare and heterogeneous disease complex of unknown origin which basically affects cartilaginous structures, 40% of which accompanied by rheumatic, hematologic, and endocrine disease. Among them, vasculitis is the most common accompanying type and usually presented with positive antineutrophilic cytoplasmic antibody (ANCA). The presence of ANCA could be primary or drug-induced like propylthiouracil (PTU). Central involvement of RP is very rare, and there is almost no report of cerebral vasculopathy manifested as moyamoya...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29389690/inflammatory-pseudotumor-induced-proptosis-in-a-patient-with-relapsing-polychondritis
#13
M Anthony Albornoz, Michael Philip Baldassari, Christian Anthony Albornoz, Garen Boghosian
No abstract text is available yet for this article.
January 31, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29384827/idiopathic-sclerosing-orbital-inflammation-in-a-relapsing-polychondritis-patient-with-impaired-vision
#14
Chrong-Reen Wang, Sheng-Min Hsu, Ying-Chen Chen, Chung-Liang Ho, Sheen-Yie Fang
A 55-year-old woman with relapsing polychondritis had progressively enlarged right retro-orbital tumor invading the optic nerve, followed by left retrobulbar infiltrating lesions despite prescription of high-dose corticosteroids and pulse methylprednisolone. Repeated histopathologic analyses showed dense collagen fibers with scanty inflammatory cells, consistent with the diagnosis of idiopathic sclerosing orbital inflammation. This disorder has been recognized as a distinct entity with unique clinical features and coexisting rheumatologic disorders, requiring more focused diagnostic strategies and therapeutic regimens...
January 30, 2018: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29283700/relapsing-polychondritis-is-a-lung-disease-my-story
#15
Marcela A Ferrada
No abstract text is available yet for this article.
March 2018: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29280824/a-case-of-relapsing-polychondritis-mimicking-hemophagocytic-lymphohistiocytosis-after-propionibacterium-acnes-infection
#16
William E Monaco, Carey J Field, Thomas H Taylor
We describe a 69-year-old man who presented with a right sternocleidomastoid intramuscular abscess that grew Propionibacterium acnes. Despite initial improvement with antibiotics, he subsequently developed signs and symptoms fulfilling diagnostic criteria for hemophagocytic lymphohistiocytosis (HLH)-fevers, cytopenias, hyperferritinemia, splenomegaly, and low natural killer cell activity. The patient improved spontaneously but at outpatient follow-up complained of erythema over the bridge of his nose as well as bilateral ear redness sparing the earlobes at which point relapsing polychondritis (RP) was diagnosed...
December 27, 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/29245187/news-on-relapsing-polychondritis-the-patients-experience
#17
EDITORIAL
Jean-Charles Piette, Jérémie Dion, Nathalie Costedoat-Chalumeau
In this issue of Arthritis Care & Research, the authors of Patient-Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis report for the first time the patient's view over the disease (1). Thanks go to them for this important step forward. The method used however, carries some limitations, as indicated very honestly by the authors. This article is protected by copyright. All rights reserved.
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245173/patient-perception-of-disease-related-symptoms-and-complications-in-relapsing-polychondritis
#18
Marcela A Ferrada, Peter C Grayson, Shubhasree Banerjee, Keith Sikora, Robert Colbert, Ninet Sinaii, James D Katz
OBJECTIVE: To assess patient-reported symptoms and burden of disease in relapsing polychondritis (RP). METHODS: Patients with RP completed a disease-specific online survey to identify symptoms attributed to illness. Patients were divided into subgroups based upon presence or absence of ear/nose, airway, or joint involvement. Pathway to diagnosis, treatment, and disease-related complications were assessed within each subgroup. RESULTS: Data from 304 respondents were included in this analysis...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29234846/fdg-pet-ct-as-a-powerful-tool-for-diagnosing-and-monitoring-treatment-outcomes-of-relapsing-polychondritis
#19
Pauline Baudart, Achille Aouba, Marie Beaufrère, Nicolas Aide
No abstract text is available yet for this article.
April 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29218258/breaking-the-magic-mouth-and-genital-ulcers-with-inflamed-cartilage-syndrome
#20
REVIEW
Stella Pak, Shaina Logemann, Christine Dee, Adam Fershko
Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome refers to a condition in which features of Behcet's disease (BD) and relapsing polychondritis (RP) occur in the same individual. The existence of MAGIC syndrome suggests a potential common etiology for BD and RP. However, connecting these two diseases and referring to this condition as MAGIC syndrome might have been premature, as there is currently insufficient knowledge on BD and RP. In this critical review, we argue that these two clinical entities could possibly be unique disease processes rather than two ends of the same disease spectrum...
October 4, 2017: Curēus
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