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David I Shapiro-Ilan, Ted E Cottrell, Russell F Mizell, Dan L Horton
The peachtree borer, Synanthedon exitiosa (Say 1823), is a major pest of stone fruit trees in North America. Current management relies upon preventative control using broad-spectrum chemical insecticides, primarily chlorpyrifos, applied in the late summer or early fall. However, due to missed applications, poor application timing, or other factors, high levels of S. exitiosa infestation may still occur and persist through the following spring. Curative treatments applied in the spring to established infestations would limit damage to the tree and prevent the next generation of S...
September 2016: Journal of Nematology
Jessica A Flynn, Eberhard Durr, Ryan Swoyer, Pedro J Cejas, Melanie S Horton, Jennifer D Galli, Scott A Cosmi, Amy S Espeseth, Andrew J Bett, Lan Zhang
Infection with Respiratory Syncytial Virus (RSV) causes both upper and lower respiratory tract disease in humans, leading to significant morbidity and mortality in both young children and older adults. Currently, there is no licensed vaccine available, and therapeutic options are limited. During the infection process, the type I viral fusion (F) glycoprotein on the surface of the RSV particle rearranges from a metastable prefusion conformation to a highly stable postfusion form. In people naturally infected with RSV, most potent neutralizing antibodies are directed to the prefusion form of the F protein...
2016: PloS One
Mike Horton, Amanda E Perry
Aims and method To explore the modern psychometric properties of the Patient Health Questionnaire (PHQ-9), we used the Rasch analysis in a sample of 767 primary care patients with depression. Results The analysis highlighted dependency issues between items 1 and 2 ('Little interest or pleasure in doing things' and 'Feeling down, depressed, or hopeless'), and items 3 and 4 ('Trouble falling or staying asleep, or sleeping too much' and 'Feeling tired or having little energy'). Items 1 and 2 displayed an over-discrimination, suggesting their potential redundancy within the complete item set...
October 2016: BJPsych Bulletin
Richard Horton
No abstract text is available yet for this article.
October 15, 2016: Lancet
Richard Horton, Udani Samarasekera
No abstract text is available yet for this article.
October 13, 2016: Lancet
Pantelis A Sarafidis, Vasilios Kamperidis, Charalampos Loutradis, Konstantinos Tsilonis, Fani Mpoutsiouki, Athanasios Saratzis, Georgios Giannakoulas, Georgios Sianos, Haralambos Karvounis
BACKGROUND: The effect of acute preload reduction during haemodialysis on left ventricle (LV) and right ventricle (RV) function is not well understood. This study aimed to evaluate acute changes in novel echocardiographic and tissue Doppler-derived indices of LV and RV function during the first and a standard weekly dialysis session and to examine the possible effect of acute intradialytic volume changes in LV and RV diastolic function and pulmonary circulation loading. METHODS: Forty-one adult patients receiving standard thrice-weekly haemodialysis participated in this study...
October 13, 2016: Nephrology, Dialysis, Transplantation
Richard Horton
No abstract text is available yet for this article.
October 8, 2016: Lancet
Nigel Crisp, David Stuckler, Richard Horton, Victor Adebowale, Sue Bailey, Maureen Baker, John Bell, John Bird, Carol Black, Jane Campbell, Janet Davies, Heather Henry, Robert Lechler, Andrew Mawson, Patrick H Maxwell, Martin McKee, Cathy Warwick
Brexit and the troubled state of the NHS call for re-thinking the UK's approach to health. The EU referendum vote reveals deep social divisions as well as presenting the country with important decisions and negotiations about the future. At the same time, health problems are growing; the NHS faces severe financial constraints and appears to lurch from crisis to crisis, with leaving the European Union likely to exacerbate many problems including staffing issues across the whole sector. However, new scientific developments and digital technology offer societies everywhere massive and unprecedented opportunities for improving health...
October 6, 2016: Lancet
Selina Lo, Pamela Das, Richard Horton
No abstract text is available yet for this article.
October 4, 2016: Lancet
Travis T Wager, Thomas A Chappie, David Horton, Ramalakshmi Y Chandrasekaran, Brian M Samas, Elizabeth Dunn-Sims, Cathleen Hsu, Nawshaba Nawreen, Michelle A Vanase-Frawley, Rebecca E O'Connor, Christopher Schmidt, Keith Dlugolenski, Nancy C Stratman, Mark J Majchrzak, Bethany L Kormos, David Nguyen, Aarti Sawant-Basak, Andy N Mead
Dopamine receptor antagonism is a compelling molecular target for the treatment of a range of psychiatric disorders, including substance use disorders. From our corporate compound file we identified a structurally unique D3 receptor (D3R) antagonist scaffold, 1. Through a hybrid approach, we merged key pharmacophore elements from 1 and D3 agonist 2 to yield the novel D3R/D2R antagonist PF-4363467 (3). Compound 3 was designed to possess CNS drug-like properties as defined by its CNS MPO desirability score (≥4/6)...
October 7, 2016: ACS Chemical Neuroscience
Mia Tinari, Elliot K Fishman, Karen M Horton, Siva P Raman
No abstract text is available yet for this article.
October 2016: Journal of the American College of Radiology: JACR
Richard Horton
No abstract text is available yet for this article.
October 1, 2016: Lancet
William B Horton, Patrick L Boler, Angela R Subauste
Diabetes mellitus (DM) is a heterogeneous condition characterized by hyperglycemia as a consequence of defects in insulin secretion and variable degrees of insulin resistance. DM is the most common endocrine disorder in the United States, affecting 9.3% of the population (29.1 million people) in 2014. Skin disorders are present in 79.2% of patients with DM, and cutaneous disease may appear as the first sign of DM or develop at any time in the course of the disease. Given the increasing incidence and prevalence of DM in the United States, primary care physicians should be aware of the associated cutaneous manifestations...
October 2016: Southern Medical Journal
Daniel E Lynch, Graham Smith, Tony D Keene, Peter N Horton
The study of ternary systems is interesting because it introduces the concept of molecular preference/competition into the system where one molecule may be displaced because the association between the other two is significantly stronger. Current definitions of a tertiary system indicate that solvent molecules are excluded from the molecule count of the system and some of the latest definitions state that any molecule that is not a solid in the parent form at room temperature should also be excluded from the molecule count...
October 1, 2016: Acta Crystallographica. Section C, Structural Chemistry
Chih-Ju Lin, Feng-Chieh Li, Yu-Yang Lee, Te-Yu Tseng, Wei-Liang Chen, Vladimir Hovhannisyan, Ning Kang, Nicholas G Horton, Shu-Jen Chiang, Chris Xu, Hsuan-Shu Lee, Chen-Yuan Dong
Hepatobiliary metabolism is one of the major functions of the liver. However, little is known of the relationship between the physiological location of the hepatocytes and their metabolic potential. By the combination of time-lapse multiphoton microscopy and first order kinetic constant image analysis, the hepatocellular metabolic rate of the model compound 6-carboxyfluorescein diacetate (6-CFDA) is quantified at the single cell level. We found that the mouse liver can be divided into three zones, each with distinct metabolic rate constants...
September 1, 2016: Biomedical Optics Express
Alice A Horton, Claus Svendsen, Richard J Williams, David J Spurgeon, Elma Lahive
: Sewage effluent input and population were chosen as predictors of microplastic presence in sediments at four sites in the River Thames basin (UK). Large microplastic particles (1mm-4mm) were extracted using a stepwise approach to include visual extraction, flotation and identification using Raman spectroscopy. Microplastics were found at all four sites. One site had significantly higher numbers of microplastics than other sites, average 66 particles 100g(-1), 91% of which were fragments...
September 27, 2016: Marine Pollution Bulletin
G S Thekkadath, L Giner, Y Chalich, M J Horton, J Banker, J S Lundeen
One drawback of conventional quantum state tomography is that it does not readily provide access to single density matrix elements since it requires a global reconstruction. Here, we experimentally demonstrate a scheme that can be used to directly measure individual density matrix elements of general quantum states. The scheme relies on measuring a sequence of three observables, each complementary to the last. The first two measurements are made weak to minimize the disturbance they cause to the state, while the final measurement is strong...
September 16, 2016: Physical Review Letters
T Velasquez, G Mackey, J Lusk, U G Kyle, T Fontenot, P Marshall, L S Shekerdemian, J A Coss-Bu, A Nishigaki, T Yatabe, T Tamura, K Yamashita, M Yokoyama, J C Ruiz-Rodriguez, B Encina, R Belmonte, I Troncoso, P Tormos, M Riveiro, J Baena, A Sanchez, J Bañeras, J Cordón, N Duran, A Ruiz, J Caballero, X Nuvials, J Riera, J Serra, A M F Rutten, S N M van Ieperen, E P H M Der Kinderen, T Van Logten, L Kovacikova, P Skrak, M Zahorec, U G Kyle, A Akcan-Arikan, J C Silva, G Mackey, J Lusk, M Goldsworthy, L S Shekerdemian, J A Coss-Bu, D Wood, D Harrison, R Parslow, P Davis, J Pappachan, S Goodwin, P Ramnarayan, S Chernyshuk, H Yemets, V Zhovnir, S M Pulitano', S De Rosa, A Mancino, G Villa, F Tosi, P Franchi, G Conti, B Patel, H Khine, A Shah, D Sung, L Singer, S Haghbin, S Inaloo, Z Serati, M Idei, T Nomura, N Yamamoto, Y Sakai, T Yoshida, Y Matsuda, Y Yamaguchi, S Takaki, O Yamaguchi, T Goto, N Longani, S Medar, I R Abdel-Aal, A S El Adawy, H M E H Mohammed, A N Mohamed, S M Parry, L D Knight, L Denehy, N De Morton, C E Baldwin, D Sani, G Kayambu, V Z M da Silva, P Phongpagdi, Z A Puthucheary, C L Granger, J E Rydingsward, C M Horkan, K B Christopher, D McWilliams, C Jones, E Reeves, G Atkins, C Snelson, L M Aitken, J Rattray, J Kenardy, A M Hull, A Ullman, R Le Brocque, M Mitchell, C Davis, B Macfarlane, J C Azevedo, L L Rocha, F F M De Freitas, A M Cavalheiro, N M Lucinio, M S Lobato, G Ebeling, A Kraegpoeth, E Laerkner, I De Brito-Ashurst, C White, S Gregory, L G Forni, E Flowers, A Curtis, C A Wood, K Siu, K Venkatesan, J B H Muhammad, L Ng, E Seet, N Baptista, A Escoval, E Tomas, R Agrawal, R Mathew, A Varma, E Dima, E Charitidou, E Perivolioti, M Pratikaki, C Vrettou, A Giannopoulos, S Zakynthinos, C Routsi, E Atchade, S Houzé, S Jean-Baptiste, G Thabut, C Genève, S Tanaka, B Lortat-Jacob, P Augustin, M Desmard, P Montravers, F J González de Molina, S Barbadillo, R Alejandro, F Álvarez-Lerma, J Vallés, R M Catalán, E Palencia, A Jareño, R M Granada, M L Ignacio, N Cui, D Liu, H Wang, L Su, H Qiu, R Li, K Jaffal, A Rouzé, J Poissy, B Sendid, S Nseir, E Paramythiotou, M Rizos, F Frantzeskaki, A Antoniadou, S Vourli, L Zerva, A Armaganidis, J Riera, J Gottlieb, M Greer, O Wiesner, M Martínez, M Acuña, J Rello, T Welte, E Atchade, T Mignot, S Houzé, S Jean-Baptiste, G Thabut, B Lortat-Jacob, S Tanaka, P Augustin, M Desmard, P Montravers, S Soussi, E Dudoignon, A Ferry, M Chaussard, M Benyamina, A Alanio, S Touratier, M Chaouat, M Lafaurie, M Mimoun, A Mebazaa, M Legrand, M A Sheils, C Patel, L Mohankumar, N Akhtar, S K Pacheco Noriega, N Navarrete Aldana, J L Ávila León, J Durand Baquero, F Fernández Bernal, E Ahmadnia, J S Hadley, M Millar, D Hall, H Hewitt, H Yasuda, M Sanui, T Komuro, S Kawano, K Andoh, H Yamamoto, E Noda, J Hatakeyama, N Saitou, H Okamoto, A Kobayashi, T Takei, S Matsukubo, H B Rotzel, A Serrano Lázaro, D Aguillón Prada, M Rodriguez Gimillo, O Diaz Barinas, M L Blasco Cortes, J Ferreres Franco, J M Segura Roca, A Carratalá, B Gonçalves, R Turon, A Mendes, F Miranda, P J Mata, D Cavalcanti, N Melo, P Lacerda, P Kurtz, C Righy, L E de la Cruz Rosario, S P Gómez Lesmes, J C García Romero, A N García Herrera, E D Díaz Pertuz, M J Gómez Sánchez, E Regidor Sanz, J Barado Hualde, A Ansotegui Hernández, J M Guergué Irazabal, V Spatenkova, O Bradac, P Suchomel, T Urli, E Heusch Lazzeri, R Aspide, M Zanello, L Perez-Borrero, J M Garcia-Alvarez, M D Arias-Verdu, E Aguilar-Alonso, R Rivera-Fernandez, J Mora-Ordoñez, C De La Fuente-Martos, E Castillo-Lorente, F Guerrero-Lopez, S P Gómez Lesmes, L E De la Cruz Rosario, E D Díaz Pertuz, A Ansotegui Hernández, J C García Romero, M J Gómez Sánchez, A N García Herrera, J Roldán Ramírez, E Regidor Sanz, J Barado Hualde, J P Tirapu León, L Navarro-Guillamón, S Cordovilla-Guardia, A Iglesias-Santiago, F Guerrero-López, E Fernández-Mondéjar, A Vidal, M Perez, A Juez, N Arias, L Colino, J L Perez, H Pérez, P Calpe, M A Alcala, D Robaglia, C Perez, S K Lan, M M Cunha, T Moreira, F Santos, E Lafuente, M J Fernandes, J G Silva, L E de la Cruz Rosario, S P Gómez Lesmes, A N García Herrera, J C García Romero, E D Díaz Pertuz, M J Gómez Sánchez, E Regidor Sanz, J G Armando Echeverría, A Ansotegui Hernández, J Barado Hualde, V Podlepich, E Sokolova, E Alexandrova, K Lapteva, P Kurtz, C Shuinotsuka, L Rabello, G Vianna, A Reis, C Cairus, J Salluh, F Bozza, J C Barrios Torres, N J Fernández Araujo, P García-Olivares, E Keough, M Dalorzo, L K Tang, I De Sousa, M Díaz, L J Marcos-Zambrano, J E Guerrero, S E Zamora Gomez, G D Hernandez Lopez, A I Vazquez Cuellar, O R Perez Nieto, J A Castanon Gonzalez, D Bhasin, S Rai, H Singh, O Gupta, M K Bhattal, S Sampley, K Sekhri, R Nandha, F A Aliaga, F Olivares, F Appiani, P Farias, F Alberto, A Hernández, S Pons, R Sonneville, L Bouadma, M Neuville, E Mariotte, A Radjou, J Lebut, S Chemam, G Voiriot, M P Dilly, B Mourvillier, R Dorent, P Nataf, M Wolff, J F Timsit, O Ediboglu, S Ataman, H Ozkarakas, C Kirakli, A Vakalos, V Avramidis, O Obukhova, I A Kurmukov, S Kashiya, E Golovnya, V N Baikova, T Ageeva, T Haritydi, E V Kulaga, J J Rios-Toro, L Perez-Borrero, E Aguilar-Alonso, M D Arias-Verdu, J M Garcia-Alvarez, C Lopez-Caler, C De La Fuente-Martos, S Rodriguez-Fernandez, M Gomez Sanchez-Orézzoli, F Martin-Gallardo, J Nikhilesh, V Joshi, E Villarreal, J Ruiz, M Gordon, A Quinza, J Gimenez, M Piñol, A Castellanos, P Ramirez, Y D Jeon, W Y Jeong, M H Kim, I Y Jeong, M Y Ahn, J Y Ahn, S H Han, J Y Choi, Y G Song, J M Kim, N S Ku, H Shah, F Kellner, F Rezai, N Mistry, P Yodice, V Ovnanian, K Fless, E Handler, R Martínez Alejos, J D Martí Romeu, D González Antón, A Quinart, A Torres Martí, M Llaurado-Serra, A Lobo-Civico, A Ventura-Rosado, A Piñol-Tena, M Pi-Guerrero, C Paños-Espinosa, M Peralvo-Bernat, J Marine-Vidal, R Gonzalez-Engroba, N Montesinos-Cerro, M Treso-Geira, A Valeiras-Valero, L Martinez-Reyes, A Sandiumenge, M F Jimenez-Herrera, S Helyar, P Riozzi, A Noon, G Hallows, H Cotton, J Keep, P A Hopkins, A Taggu, S Renuka, S Sampath, P J T Rood, T Frenzel, R Verhage, M Bonn, P Pickkers, J G van der Hoeven, M van den Boogaard, F Corradi, L Melnyk, F Moggia, R Pienovi, G Adriano, C Brusasco, L Mariotti, M Lattuada, M J Bloomer, M Coombs, K Ranse, R Endacott, B Maertens, K Blot, S Blot, M P van Nieuw Amerongen, E S van der Heiden, J W R Twisk, A R J Girbes, J J Spijkstra, P Riozzi, S Helyar, H Cotton, G Hallows, A Noon, C Bell, K Peters, A Feehan, J Keep, P A Hopkins, K Churchill, K Hawkins, R Brook, N Paver, R Endacott, N Maistry, A van Wijk, N Rouw, T van Galen, S Evelein-Brugman, A Taggu, B Krishna, S Sampath, A Putzu, M Fang, M Boscolo Berto, A Belletti, T Cassina, L Cabrini, M Mistry, Y Alhamdi, I Welters, S T Abrams, C H Toh, H S Han, E M Gil, D S Lee, C M Park, S Winder-Rhodes, R Lotay, J Doyle, M W Ke, W C Huang, C H Chiang, W T Hung, C C Cheng, K C Lin, S C Lin, K R Chiou, S R Wann, C W Shu, P L Kang, G Y Mar, C P Liu, S Dubó, A Aquevedo, M Jibaja, D Berrutti, C Labra, R Lagos, M F García, V Ramirez, M Tobar, F Picoita, C Peláez, D Carpio, L Alegría, C Hidalgo, K Godoy, J Bakker, G Hernández, Y Sadamoto, K Katabami, T Wada, Y Ono, K Maekawa, M Hayakawa, A Sawamura, S Gando, H Marin-Mateos, J L Perez-Vela, R Garcia-Gigorro, M A Corres Peiretti, M J Lopez-Gude, S Chacon-Alves, E Renes-Carreño, J C Montejo-González, K L Parlevliet, H R W Touw, M Beerepoot, C Boer, P W G Elbers, P R Tuinman, S A Abdelmonem, T A Helmy, I El Sayed, S Ghazal, S H Akhlagh, M Masjedi, K Hozhabri, E Kamali, I Zýková, B Paldusová, P Sedlák, D Morman, A M Youn, Y Ohta, M Sakuma, D Bates, T Morimoto, P L Su, W Y Chang, W C Lin, C W Chen, F Facchin, F Zarantonello, G Panciera, A De Cassai, A Venrdramin, A Ballin, T Tonetti, P Persona, C Ori, L Del Sorbo, S Rossi, G Vergani, M Cressoni, D Chiumello, C Chiurazzi, M Brioni, I Algieri, T Tonetti, M Guanziroli, A Colombo, I Tomic, A Colombo, F Crimella, E Carlesso, V Gasparovic, L Gattinoni, A Serpa Neto, M Schmidt, T Pham, A Combes, M Gama de Abreu, P Pelosi, M J Schultz, B H Katira, D Engelberts, R E Giesinger, C Ackerley, T Yoshida, D Zabini, G Otulakowski, M Post, W M Kuebler, P J McNamara, B P Kavanagh, R Pirracchio, M Resche Rigon, M Carone, S Chevret, D Annane, S Eladawy, M El-Hamamsy, N Bazan, M Elgendy, G De Pascale, M S Vallecoccia, S L Cutuli, V Di Gravio, M A Pennisi, G Conti, M Antonelli, D T Andreis, W Khaliq, M Singer, J Hartmann, S Harm, S Alcantara Carmona, P Matia Almudevar, A Naharro Abellán, J Veganzones Ramos, L Pérez Pérez, B Lobo Valbuena, N Martínez Sanz, I Fernández Simón, M Arrigo, E Feliot, N Deye, A Cariou, B Guidet, S Jaber, M Leone, M Resche-Rigon, A Vieillard Baron, M Legrand, E Gayat, A Mebazaa, M Balik, I Kolnikova, M Maly, P Waldauf, G Tavazzi, J Kristof, A Herpain, F Su, E Post, F Taccone, J L Vincent, J Creteur, C Lee, F Hatib, Z Jian, S Buddi, M Cannesson, S Fileković, M Turel, R Knafelj, V Gorjup, R Stanić, P Gradišek, O Cerović, T Mirković, M Noč, J Tirkkonen, H Hellevuo, K T Olkkola, S Hoppu, K C Lin, W T Hung, C C Chiang, W C Huang, W C Juan, S C Lin, C C Cheng, P H Lin, K Y Fong, D S Hou, P L Kang, S R Wann, Y S Chen, G Y Mar, C P Liu, M Paul, W Bougouin, G Geri, F Dumas, B Champigneulle, S Legriel, J Charpentier, J P Mira, C Sandroni, A Cariou, J Zimmerman, E Sullivan, M Noursadeghi, B Fox, D Sampson, L McHugh, T Yager, S Cermelli, T Seldon, S Bhide, R A Brandon, R B Brandon, J Zwaag, R Beunders, P Pickkers, M Kox, F Gul, M K Arslantas, D Genc, N Zibandah, L Topcu, T Akkoc, I Cinel, E Greco, M P Lauretta, D T Andreis, M Singer, I Palacios Garcia, M Cordero, A Diaz Martin, T Aldabó Pallás, J Garnacho Montero, J Revuelto Rey, L Roman Malo, A A Tanaka Montoya, A D C Amador Martinez, L Y Delgado Ayala, E Monares Zepeda, J Franco Granillo, J Aguirre Sanchez, G Camarena Alejo, A Rugerio Cabrera, A Pedraza Montenegro, T Pham, G Beduneau, F Schortgen, L Piquilloud, E Zogheib, M Jonas, F Grelon, I Runge, N Terzi, S Grangé, G Barberet, P G Guitard, J P Frat, A Constan, J M Chrétien, J Mancebo, A Mercat, J C M Richard, L Brochard, E Soilemezi, E Koco, S Savvidou, C Nouris, D Matamis, R Di Mussi, S Spadaro, C A Volta, M Mariani, A Colaprico, C Antonio, F Bruno, S Grasso, A Rodriguez, I Martín-Loeches, E Díaz, J R Masclans, F Gordo, J Solé-Violán, M Bodí, F X Avilés-Jurado, S Trefler, M Magret, L F Reyes, J Marín-Corral, J C Yebenes, A Esteban, A Anzueto, S Aliberti, M I Restrepo, J Skytte Larsson, B Redfors, S E Ricksten, R Haines, J Powell-Tuck, H Leonard, M Ostermann, R E Berthelsen, T S Itenov, A Perner, J U Jensen, M Ibsen, A E K Jensen, M H Bestle, T Bucknall, J Dixon, F Boa, I MacPhee, B J Philips, J Doyle, F Saadat, T Samuels, S Huddart, B McCormick, R DeBrunnar, J Preece, M Swart, C Peden, S Richardson, L Forni, P Kalfon, K Baumstarck, P Estagnasie, M A Geantot, A Berric, G Simon, B Floccard, T Signouret, M Boucekine, M Fromentin, M Nyunga, A Sossou, M Venot, R Robert, A Follin, A Renault, M Garrouste, O Collange, Q Levrat, I Villard, D Thévenin, J Pottecher, R G Patrigeon, N Revel, C Vigne, O Mimoz, P Auquier, S Pawar, T Jacques, K Deshpande, R Pusapati, B Wood, R A Pulham, J Wray, K Brown, C Pierce, S Nadel, P Ramnarayan, J R Azevedo, W S Montenegro, D P Rodrigues, S C Sousa, V F Araujo, A L Leitao, P H Prazeres, A V Mendonca, M P Paula, A Das Neves, C I Loudet, M Busico, D Vazquez, D Villalba, A Lischinsky, M Veronesi, M Emmerich, E Descotte, A Juliarena, M Carboni Bisso, M Grando, A Tapia, M Camargo, D Villani Ulla, L Corzo, H Placido Dos Santos, A Ramos, J A Doglia, E Estenssoro, M Carbonara, S Magnoni, C L Mac Donald, J S Shimony, V Conte, F Triulzi, F Stretti, M Macrì, A Z Snyder, N Stocchetti, D L Brody, V Podlepich, V Shimanskiy, I Savin, K Lapteva, A Chumaev, M C Tjepkema-Cloostermans, J Hofmeijer, A Beishuizen, H Hom, M J Blans, M J A M van Putten, L Longhi, B Frigeni, M Curinga, D Mingone, S Beretta, A Patruno, L Gandini, A Vargiolu, F Ferri, R Ceriani, M R Rottoli, L Lorini, G Citerio, S Pifferi, M Battistini, V Cordolcini, A Agarossi, R Di Rosso, F Ortolano, N Stocchetti, C Mora Lourido, J L Santana Cabrera, J D Martín Santana, L Melián Alzola, C García Del Rosario, H Rodríguez Pérez, R Lorenzo Torrent, S Eslami, A Dalhuisen, T Fiks, M J Schultz, A Abu Hanna, P E Spronk, M Wood, D Maslove, J Muscedere, S H Scott, T Saha, A Hamilton, D Petsikas, D Payne, J G Boyd, Z A Puthucheary, A S McNelly, J Rawal, B Connolly, M J McPhail, P Sidhu, A Rowlerson, J Moxham, S D Harridge, N Hart, H E Montgomery, T Jovaisa, B Thomas, D Gupta, D S Wijayatilake, H P Shum, H S King, K C Chan, K B Tang, W W Yan, C Castro Arias, J Latorre, A Suárez De La Rica, E Maseda Garrido, A Montero Feijoo, C Hernández Gancedo, A López Tofiño, F Gilsanz Rodríguez, L K Gemmell, R Campbell, P Doherty, A MacKay, N Singh, S Vitaller, H Nagib, J Prieto, A Del Arco, B Zayas, C Gomez, S Tirumala, S A Pasha, B K Kumari, P Martinez-Lopez, A Puerto-Morlán, P Nuevo-Ortega, L Martinez Pujol, R Algarte Dolset, B Sánchez González, S Quintana Riera, J Trenado Álvarez, S Quintana, L Martínez, R Algarte, B Sánchez, J Trenado, E Tomas, N Brock, E Viegas, E Filipe, D Cottle, T Traynor, M V Trasmonte Martínez, M Pérez Márquez, L Colino Gómez, N Arias Martínez, J M Milicua Muñoz, B Quesada Bellver, M Muñoz Varea, M Á Alcalá Llorente, C Pérez Calvo, S D Hillier, M C Faulds, H Hendra, N Lawrence, K Maekawa, M Hayakawa, Y Ono, A Kodate, Y Sadamoto, N Tominaga, A Mizugaki, H Murakami, T Yoshida, K Katabami, T Wada, A Sawamura, S Gando, S Silva, L Kerhuel, B Malagurski, G Citerio, R Chabanne, S Laureys, L Puybasset, L Nobile, E R Pognuz, A O Rossetti, F Verginella, N Gaspard, J Creteur, N Ben-Hamouda, M Oddo, F S Taccone, Y Ono, M Hayakawa, H Iijima, K Maekawa, A Kodate, Y Sadamoto, A Mizugaki, H Murakami, K Katabami, T Wada, A Sawamura, S Gando, A Kodate, K Katabami, T Wada, Y Ono, K Maekawa, M Hayakawa, A Sawamura, S Gando, L W Andersen, T Raymond, R Berg, V Nadkarni, A Grossestreuer, T Kurth, M Donnino, 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September 2016: Intensive Care Medicine Experimental
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Gerretsen, Q de Mast, S El Messaoudi, G Rongen, M Gomes, M Kox, P Pickkers, N P Riksen, Y Kashiwagi, M Okada, K Hayashi, Y Inagaki, S Fujita, M N Nakamae, Y R Kang, R B Souza, A M A Liberatore, I H J Koh, A Blet, M Sadoune, J Lemarié, N Bihry, R Bern, E Polidano, R Merval, J M Launay, B Lévy, J L Samuel, A Mebazaa, J Hartmann, S Harm, V Weber
No abstract text is available yet for this article.
September 2016: Intensive Care Medicine Experimental
Christopher James, Johnny Millar, Stephen Horton, Christian Brizard, Charlotte Molesworth, Warwick Butt
PURPOSE: Cardiopulmonary bypass induces an ischaemia-reperfusion injury and systemic inflammatory response, which contributes to low cardiac output syndrome following cardiac surgery. Exogenous nitric oxide during cardiopulmonary bypass has shown potential to ameliorate such injury. We undertook a large randomised controlled trial to investigate the clinical effects of administering nitric oxide to the cardiopulmonary bypass circuit in children. METHODS: After written informed consent, children were randomised to receive 20 ppm nitric oxide to the gas inflow of the cardiopulmonary bypass oxygenator, or standard conduct of bypass...
September 30, 2016: Intensive Care Medicine
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