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https://www.readbyqxmd.com/read/28108600/-candidatus-liberibacter-solanacearum-associated-with-the-psyllid-bactericera-maculipennis-hemiptera-triozidae
#1
Karina M Borges, W Rodney Cooper, Stephen F Garczynski, Jenita Thinakaran, Andy S Jensen, David R Horton, Joseph E Munyaneza, Isabel Cueva, Nina M Barcenas
The psyllid Bactericera maculipennis (Crawford) (Hemiptera: Triozidae) often cohabits field bindweed (Convolvulus arvensis, Solanales: Convolvulaceae) and other plants with the congeneric psyllid, Bactericera cockerelli (Šulc), in the Pacific Northwestern United States. Bactericera cockerelli is a vector of "Candidatus Liberibacter solanacearum," the pathogen associated with zebra chip disease of potato (Solanales: Solanaceae). Because B. maculipennis and B. cockerelli both naturally occur on certain plants, we surveyed B...
January 20, 2017: Environmental Entomology
https://www.readbyqxmd.com/read/28107125/dean-s-update
#2
Mick Horton
No abstract text is available yet for this article.
November 1, 2016: Primary Dental Journal
https://www.readbyqxmd.com/read/28102128/offline-the-possible-impossibility-of-universal-health-coverage
#3
Richard Horton
No abstract text is available yet for this article.
January 14, 2017: Lancet
https://www.readbyqxmd.com/read/28096339/loss-of-astrocyte-cholesterol-synthesis-disrupts-neuronal-function-and-alters-whole-body-metabolism
#4
Heather A Ferris, Rachel J Perry, Gabriela V Moreira, Gerald I Shulman, Jay D Horton, C Ronald Kahn
Cholesterol is important for normal brain function. The brain synthesizes its own cholesterol, presumably in astrocytes. We have previously shown that diabetes results in decreased brain cholesterol synthesis by a reduction in sterol regulatory element-binding protein 2 (SREBP2)-regulated transcription. Here we show that coculture of control astrocytes with neurons enhances neurite outgrowth, and this is reduced with SREBP2 knockdown astrocytes. In vivo, mice with knockout of SREBP2 in astrocytes have impaired brain development and behavioral and motor defects...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28095985/open-preperitoneal-groin-hernia-repair-with-mesh-a-qualitative-systematic-review
#5
REVIEW
Kristoffer Andresen, Jacob Rosenberg
BACKGROUND: For the repair of inguinal hernias, several surgical methods have been presented where the purpose is to place a mesh in the preperitoneal plane through an open access. The aim of this systematic review was to describe preperitoneal repairs with emphasis on the technique. DATA SOURCES: A systematic review was conducted and reported according to the PRISMA statement. PubMed, Cochrane library and Embase were searched systematically. Studies were included if they provided clinical data with more than 30 days follow up following repair of an inguinal hernia with an open preperitoneal mesh technique...
January 10, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28091782/adaptation-perceptual-learning-and-plasticity-of-brain-functions
#6
REVIEW
Jonathan C Horton, Manfred Fahle, Theo Mulder, Susanne Trauzettel-Klosinski
The capacity for functional restitution after brain damage is quite different in the sensory and motor systems. This series of presentations highlights the potential for adaptation, plasticity, and perceptual learning from an interdisciplinary perspective. The chances for restitution in the primary visual cortex are limited. Some patterns of visual field loss and recovery after stroke are common, whereas others are impossible, which can be explained by the arrangement and plasticity of the cortical map. On the other hand, compensatory mechanisms are effective, can occur spontaneously, and can be enhanced by training...
January 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28091699/musculoskeletal-mri-findings-of-juvenile-localized-scleroderma
#7
Eric P Eutsler, Daniel B Horton, Monica Epelman, Terri Finkel, Lauren W Averill
BACKGROUND: Juvenile localized scleroderma comprises a group of autoimmune conditions often characterized clinically by an area of skin hardening. In addition to superficial changes in the skin and subcutaneous tissues, juvenile localized scleroderma may involve the deep soft tissues, bones and joints, possibly resulting in functional impairment and pain in addition to cosmetic changes. OBJECTIVE: There is literature documenting the spectrum of findings for deep involvement of localized scleroderma (fascia, muscles, tendons, bones and joints) in adults, but there is limited literature for the condition in children...
January 14, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28091367/offline-what-should-be-the-uk-s-bold-new-role
#8
Richard Horton
No abstract text is available yet for this article.
January 7, 2017: Lancet
https://www.readbyqxmd.com/read/28077231/from-universal-health-coverage-to-right-care-for-health
#9
Sabine Kleinert, Richard Horton
No abstract text is available yet for this article.
January 6, 2017: Lancet
https://www.readbyqxmd.com/read/28067232/oxidized-nucleotide-insertion-by-pol-%C3%AE-confounds-ligation-during-base-excision-repair
#10
Melike Çağlayan, Julie K Horton, Da-Peng Dai, Donna F Stefanick, Samuel H Wilson
Oxidative stress in cells can lead to accumulation of reactive oxygen species and oxidation of DNA precursors. Oxidized purine nucleotides can be inserted into DNA during replication and repair. The main pathway for correcting oxidized bases in DNA is base excision repair (BER), and in vertebrates DNA polymerase β (pol β) provides gap filling and tailoring functions. Here we report that the DNA ligation step of BER is compromised after pol β insertion of oxidized purine nucleotides into the BER intermediate in vitro...
January 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28065437/erratum-to-change-in-adiponectin-explains-most-of-the-change-in-hdl-particles-induced-by-lifestyle-intervention-but-not-metformin-treatment-in-the-diabetes-prevention-program-metabolism-2016-65-764-775
#11
Ronald B Goldberg, Marinella Temprosa, Lisa Mele, Trevor Orchard, Kieren Mather, George Bray, Edward Horton, Abbas Kitabchi, Jonathan Krakoff, Santica Marcovina, Leigh Perreault, Neil White
No abstract text is available yet for this article.
January 5, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28057805/cns-targeted-autoimmunity-leads-to-increased-influenza-mortality-in-mice
#12
Justin D Glenn, Matthew D Smith, Pei Xue, Yee Chan-Li, Samuel Collins, Peter A Calabresi, Maureen R Horton, Katharine A Whartenby
The discovery that central nervous system (CNS)-targeted autoreactive T cells required a process of licensing in the lung revealed an unexpected relationship between these organs. The clinical and immunological significance of this finding is bidirectional in that it showed not only a mechanism by which T cells become pathogenic before entering the CNS, but also the potential for this process to influence lung immunity as well. Epidemiological studies have shown that people with multiple sclerosis (MS) suffer from increased morbidity and mortality from infectious diseases, independent of immunosuppressive therapies...
January 5, 2017: Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28046484/we-ab-209-05-development-of-an-ultra-fast-high-quality-whole-breast-radiotherapy-treatment-planning-system
#13
Y Sheng, T Li, S Yoo, F Yin, R Blitzblau, J Horton, M Palta, C Hahn, Y Ge, Q Wu
PURPOSE: To enable near-real-time (<20sec) and interactive planning without compromising quality for whole breast RT treatment planning using tangential fields. METHODS: Whole breast RT plans from 20 patients treated with single energy (SE, 6MV, 10 patients) or mixed energy (ME, 6/15MV, 10 patients) were randomly selected for model training. Additional 20 cases were used as validation cohort. The planning process for a new case consists of three fully automated steps:1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28043436/endovascular-repair-of-type-a-aortic-dissection-current-experience-and-technical-considerations
#14
Joshua D Horton, Tilo Kölbel, Stephan Haulon, Ali Khoynezhad, Richard M Green, Michael A Borger, Firas F Mussa
Dissection of the ascending aorta, type A aortic dissection (TAAD), represents a surgical emergency with high morbidity and mortality. Current open surgical techniques, although state-of-the-art procedures and having improved outcomes for patients with TAAD over the last decades, confer significant risk of complications and death. Recently, endovascular techniques for repair of both the abdominal and thoracic aorta have gained acceptance within the vascular and cardiovascular surgical communities as a useful tool in select pathologies and patient populations...
July 2016: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28039211/long-term-follow-up-of-patients-with-paroxysmal-atrial-fibrillation-and-severe-left-atrial-scarring-comparison-between-pulmonary-vein-antrum-isolation-only-or-pulmonary-vein-isolation-combined-with-either-scar-homogenization-or-trigger-ablation
#15
Sanghamitra Mohanty, Prasant Mohanty, Luigi Di Biase, Chintan Trivedi, Eli Hamilton Morris, Carola Gianni, Pasquale Santangeli, Rong Bai, Javier E Sanchez, Patrick Hranitzky, G Joseph Gallinghouse, Amin Al-Ahmad, Rodney P Horton, Richard Hongo, Salwa Beheiry, Claude S Elayi, Dhanunjaya Lakkireddy, Yaruva Madhu Reddy, Juan F Viles Gonzalez, J David Burkhardt, Andrea Natale
AIMS: Left atrial (LA) scarring, a consequence of cardiac fibrosis is a powerful predictor of procedure-outcome in atrial fibrillation (AF) patients undergoing catheter ablation. We sought to compare the long-term outcome in patients with paroxysmal AF (PAF) and severe LA scarring identified by 3D mapping, undergoing pulmonary vein isolation (PVAI) only or PVAI and the entire scar areas (scar homogenization) or PVAI+ ablation of the non-PV triggers. METHODS AND RESULTS: Totally, 177 consecutive patients with PAF and severe LA scarring were included...
December 29, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28028155/abatacept-reduces-disease-activity-and-ultrasound-power-doppler-in-acpa-negative-undifferentiated-arthritis-a-proof-of-concept-clinical-and-imaging-study
#16
Maya H Buch, Elizabeth M A Hensor, Chadi Rakieh, Jane E Freeston, Edward Middleton, Sarah Horton, Sudipto Das, Charles Peterfy, Ai Lyn Tan, Richard J Wakefield, Paul Emery
OBJECTIVES: No proven treatment exists for ACPA-negative undifferentiated arthritis (UA). The aim of this study was to evaluate whether abatacept is effective in treating poor prognosis, ACPA-negative UA, including its effect on power Doppler on US (PDUS). METHODS: A proof-of-concept, open-label, prospective study of 20 patients with DMARD-naïve, ACPA-negative UA (⩾2 joint synovitis) and PDUS ⩾ 1 with clinical and 20-joint US (grey scale/PDUS) assessments at baseline, 6, 12, 18 and 24 months...
January 2017: Rheumatology
https://www.readbyqxmd.com/read/28027856/the-culture-of-hospitality
#17
Nick Bayer, Elliot K Fishman, Karen M Horton, Pamela T Johnson
No abstract text is available yet for this article.
December 24, 2016: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28017400/the-lancet-planetary-health-a-new-journal-for-a-new-discipline-a-call-for-papers
#18
Raffaella Bosurgi, Richard Horton
No abstract text is available yet for this article.
January 14, 2017: Lancet
https://www.readbyqxmd.com/read/28012753/a-one-stage-hypospadias-repair
#19
Charles J Devine, Charles E Horton
No abstract text is available yet for this article.
December 21, 2016: Journal of Urology
https://www.readbyqxmd.com/read/28004808/il-13-is-a-therapeutic-target-in-radiation-lung-injury
#20
Su I Chung, Jason A Horton, Thirumalai R Ramalingam, Ayla O White, Eun Joo Chung, Kathryn E Hudak, Bradley T Scroggins, Joseph R Arron, Thomas A Wynn, Deborah E Citrin
Pulmonary fibrosis is a potentially lethal late adverse event of thoracic irradiation. Prior research indicates that unrestrained TGF-β1 and/or type 2 cytokine-driven immune responses promote fibrosis following radiation injury, but the full spectrum of factors governing this pathology remains unclear. Interleukin 13 (IL-13) is a key factor in fibrotic disease associated with helminth infection, but it is unclear whether it plays a similar role in radiation-induced lung fibrosis. Using a mouse model, we tested the hypothesis that IL-13 drives the progression of radiation-induced pulmonary fibrosis...
December 22, 2016: Scientific Reports
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