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corticosteroid injection

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https://www.readbyqxmd.com/read/29470929/interferon-alpha-2a-for-the-treatment-of-post-infectious-uveitis-secondary-to-presumed-intraocular-tuberculosis
#1
Alessandro Invernizzi, Franca Iannaccone, Sylvia Marchi, Valentina Mastrofilippo, Marco Coassin, Luigi Fontana, Carlo Salvarani, Peter McCluskey, Luca Cimino
PURPOSE: To assess the efficacy and tolerability of interferon (IFN) alpha-2a in post-infectious uveitis secondary to presumed intraocular tuberculosis (IOTB). METHODS: Patients with chronic uveitis secondary to presumed IOTB who, after completing an antitubercular treatment, showed poor response to treatments or recurred after tapering oral corticosteroids to ≤7.5 mg/day were enrolled. All patients were treated with IFN alpha-2a subcutaneous injections. Best-corrected visual acuity (BCVA), central retinal thickness (CRT), and inflammatory signs were compared between baseline and follow-up visits up to six months...
February 22, 2018: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/29469176/current-physiotherapy-practice-in-the-management-of-tennis-elbow-a-service-evaluation
#2
M Bateman, E Whitby, S Kacha, E Salt
BACKGROUND: Tennis elbow is a common painful condition that may affect daily function and ability to work. Physiotherapy is the most commonly used primary intervention but there is a wide range of treatment options within the umbrella of physiotherapy. Our aim was to report on the treatments that are currently used by physiotherapists in a UK National Health Service (NHS) setting. METHODS: A retrospective service evaluation was conducted at two NHS hospital trusts by reviewing patient attendance records over a 1-year period...
February 22, 2018: Musculoskeletal Care
https://www.readbyqxmd.com/read/29467402/development-of-a-model-predicting-non-satisfaction-1-year-after-primary-total-knee-replacement-in-the-uk-and-transportation-to-switzerland
#3
Cesar Garriga, Maria T Sanchez-Santos, Andrew Judge, Thomas Perneger, Didier Hannouche, Anne Lübbeke, Nigel K Arden
We aimed to develop a predictive model for non-satisfaction following primary total knee replacement (TKR) and to assess its transportability to another health care system. Data for model development were obtained from two UK tertiary hospitals. Model transportation data were collected from Geneva University Hospitals in Switzerland. Participants were individuals undergoing primary TKR with non-satisfaction with surgery after one year the outcome of interest. Multiple imputation and logistic regression modelling with bootstrap backward selection were used to identify predictors of outcome...
February 21, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29466690/safety-and-efficacy-of-etanercept-methotrexate-combination-therapy-in-patients-with-rhupus-an-observational-study-of-non-glucocorticoid-treatment-for-rheumatic-diseases
#4
Bei-Bei Yang, Hua Xiao, Xiao-Jie Li, Min Zheng
OBJECTIVES: To evaluate the safety and efficacy of etanercept (ETN) plus methotrexate (MTX) in patients with rhupus without using corticosteroids. METHODS: Twenty rhupus patients [meeting the criteria for both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)] who had never been treated with corticosteroids, DMARDs, or biological agents with a 28-joint Disease Activity Score (DAS28) >3.2 and lupus nephritis determined from histopathological specimens were enrolled...
January 2018: Discovery Medicine
https://www.readbyqxmd.com/read/29465442/comparison-between-corticosteroid-and-lidocaine-injection-in-the-treatment-of-tennis-elbow-a-randomized-double-blinded-controlled-trial
#5
Lin-Fen Hsieh
No abstract text is available yet for this article.
February 21, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29465441/letter-to-the-editor-involving-the-article-comparison-between-corticosteroids-and-lidocaine-injection-in-the-treatment-of-tennis-elbow-a-randomised-double-blinded-controlled-trial
#6
Peter van Schie, Kim Em Benders, Michel Pj van den Bekerom
No abstract text is available yet for this article.
February 21, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29464283/-osteoarthritis-of-the-shoulder-pathogenesis-diagnostics-and-conservative-treatment-options
#7
REVIEW
J Mehl, A B Imhoff, K Beitzel
PATHOGENESIS: Osteoarthritis of the shoulder is characterized by a progressive degenerative process, which is based on chronic inflammation with intra-articular release of different cytokines and proteolytic enzymes. The main predisposing factors are a history of trauma or surgery, as well as chronic overuse or instability of the glenohumeral joint. Affected patients especially suffer from impaired joint function and pain, which are often associated with cognitive and psychosocial restrictions...
February 20, 2018: Der Orthopäde
https://www.readbyqxmd.com/read/29460009/the-global-spine-care-initiative-applying-evidence-based-guidelines-on-the-non-invasive-management-of-back-and-neck-pain-to-low-and-middle-income-communities
#8
REVIEW
Roger Chou, Pierre Côté, Kristi Randhawa, Paola Torres, Hainan Yu, Margareta Nordin, Eric L Hurwitz, Scott Haldeman, Christine Cedraschi
PURPOSE: The purpose of this review was to develop recommendations for the management of spinal disorders in low-income communities, with a focus on non-invasive pharmacological and non-pharmacological therapies for non-specific low back and neck pain. METHODS: We synthesized two evidence-based clinical practice guidelines for the management of low back and neck pain. Our recommendations considered benefits, harms, quality of evidence, and costs, with attention to feasibility in medically underserved areas and low- and middle-income countries...
February 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29457989/propylthiouracil-induced-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis-mimicking-kawasaki-disease
#9
Yoshihiro Aoki, Katsuhiko Kitazawa, Hironobu Kobayashi
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is rare in children and is characterised as necrotising vasculitis predominantly affecting small and medium-sized vessels. Propylthiouracil (PTU), an antithyroid drug, has been implicated in drug-induced AAV. In contrast, Kawasaki disease (KD) is a common systemic vasculitis, typically observed in children, which affects the medium-sized vessels, including the coronary arteries. An 11-year-old girl who developed AAV while receiving PTU therapy for Graves' disease is described...
February 19, 2018: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/29454550/soci%C3%A3-t%C3%A3-d-imagerie-musculosquelettique-sims-f%C3%A3-d%C3%A3-ration-de-radiologie-interventionnelle-fri-and-soci%C3%A3-t%C3%A3-francophone-de-radiologie-sfr-recommendations-for-epidural-and-transforaminal-corticosteroid-injections
#10
A Cotten, J-L Drapé, N Sans, A Feydy, J-M Bartoli, J-F Meder
No abstract text is available yet for this article.
February 14, 2018: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29453201/hypercalcemia-associated-with-cosmetic-injections-a-systematic-review
#11
Niranjan Tachamo, Anthony Donato, Bidhya Timilsina, Salik Nazir, Saroj Lohani, Rashmi Dhital, Sijan Basnet
Cosmetic injections with silicone and polymethylmethacrylate are not FDA-approved for augmentation of body parts such as breast, buttock or legs, but they have been widely used for decades. Cosmetic injections can cause foreign body granulomas and occasionally severe and life-threatening hypercalcemia. We aimed to systematically analyze the published literature on cosmetic injection-associated hypercalcemia. Methods We searched relevant articles on hypercalcemia associated with various cosmetic injections and extracted relevant data on demographics, cosmetic injections used, severity of hypercalcemia, management and outcomes...
February 16, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29452450/-cost-comparison-of-licensed-intravitreal-therapies-for-insufficiently-anti-vegf-responding-fovea-involving-diabetic-macular-edema-in-germany
#12
Aljoscha S Neubauer, Christos Haritoglou, Michael W Ulbig
BACKGROUND: In the treatment of center-involving diabetic macular edema, despite initial therapy with an anti-VEGF compound, an insufficient response may occur. Further therapy options include a switch of anti-VEGF products or to corticosteroid implants, such as Fluocinolone acetonide or Dexamethasone. OBJECTIVES: Firstly, to investigate systematically which evidence-based study data are available describing the efficacy of in-label treatments after primary anti-VEGF treatment, secondly, to investigate which costs go along for the healthcare provider...
February 16, 2018: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29436373/electroacupuncture-for-the-treatment-of-calcific-tendonitis-a-pilot-study
#13
Georgios Papadopoulos, Alexandros Mavrodontidis, Antonia Liarmakopoulou, Petros Tzimas P, Georgios Angelidakis, Panagiotis Koulouvaris, Anastasios Petrou
Current treatment for calcific tendonitis consists of arm rest, anti-inflammatory medications and corticosteroid injections. If unsuccessful, a lot of clinicians suggest several physiotherapy modalities, such as shockwave therapy and electrotherapy. The purpose of our study was to assess the efficacy of electroacupuncture, as a substitute for failed medical treatment in calcific tendonitis. In a pilot study, we prospectively followed ten patients, treated with electroacupuncture for calcific tendonitis, that failed to respond to medical treatment...
January 3, 2018: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/29436106/corticosteroid-and-cortisol-serum-levels-following-intra-articular-triamcinolone-acetonide-lumbar-facet-joint-injections
#14
Rozalin R Dickson, Joel M Reid, Wayne T Nicholson, Tim J Lamer, W Michael Hooten
BACKGROUND: Facet joint steroid injections are used to treat chronic low back. However, little is known about the systemic absorption and serum levels of steroids following intra-articular facet joint injections. The primary objective of this preliminary study was to investigate the pharmacokinetics of triamcinolone acetonide following fluoroscopically guided intra-articular lumbar facet joint injections in a cohort of patients with chronic low back pain. A secondary aim was to investigate the effects of triamcinolone on serum cortisol levels following lumbar facet joint injections...
February 12, 2018: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29434572/stress-and-corticosteroids-aggravate-morphological-changes-in-the-dentate-gyrus-after-early-life-experimental-febrile-seizures-in-mice
#15
Jolien S van Campen, Ellen V S Hessel, Kirsten Bohmbach, Giorgio Rizzi, Paul J Lucassen, Sada Lakshmi Turimella, Eduardo H L Umeoka, Gideon F Meerhoff, Kees P J Braun, Pierre N E de Graan, Marian Joëls
Stress is the most frequently self-reported seizure precipitant in patients with epilepsy. Moreover, a relation between ear stress and epilepsy has been suggested. Although ear stress and stress hormones are known to influence seizure threshold in rodents, effects on the development of epilepsy (epileptogenesis) are still unclear. Therefore, we studied the consequences of ear corticosteroid exposure for epileptogenesis, under highly controlled conditions in an animal model. Experimental febrile seizures (eFS) were elicited in 10-day-old mice by warm-air induced hyperthermia, while a control group was exposed to a normothermic condition...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29432288/are-corticosteroid-injections-safe-to-inject-into-knees-with-osteoarthritis-what-are-the-long-term-effects
#16
Nimish Mittal, Mohit Bhandari, Dinesh Kumbhare
No abstract text is available yet for this article.
February 9, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29431981/injected-corticosteroids-for-plantar-heel-pain
#17
Michael J Arnold, Jonathan Gruber
No abstract text is available yet for this article.
February 1, 2018: American Family Physician
https://www.readbyqxmd.com/read/29429372/anti-inflammatory-effects-of-intra-articular-hyaluronic-acid-a-systematic-review
#18
Roy Altman, Asheesh Bedi, Ajay Manjoo, Faizan Niazi, Peter Shaw, Philip Mease
Objective Osteoarthritis (OA) is one of the leading causes of disability in the adult population. Common nonoperative treatment options include nonsteroidal anti-inflammatory drugs (NSAIDs), intra-articular corticosteroids, and intra-articular injections of hyaluronic acid (HA). HA is found intrinsically within the knee joint providing viscoelastic properties to the synovial fluid. HA therapy provides anti-inflammatory relief through a number of different pathways, including the suppression of pro-inflammatory cytokines and chemokines...
February 1, 2018: Cartilage
https://www.readbyqxmd.com/read/29429302/-research-progress-of-ocular-sustained-release-corticosteroid-delivery-systems
#19
Z Y Liu, Y Y Chen
Ocular drug delivery by conventional routes of administration cannot reach or maintain therapeutic drug concentrations in the target tissues for a long duration due to the presence of various anatomical and physiological barriers. Treatment of chronic ocular diseases especially posterior segment of ocular diseases requires novel drug delivery systems that is capable overcome these barriers for efficacious delivery. In recent years, the ocular sustained-release drug delivery system, as a new drug delivery approach, has drawn tremendous attention for its advantages of improving local drug concentration, prolonging action time and reducing frequency of injection...
February 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29426811/intralesional-cryotherapy-versus-excision-with-corticosteroid-injections-or-brachytherapy-for-keloid-treatment-randomised-controlled-trials
#20
Eveline Bijlard, Reinier Timman, Gerda M Verduijn, Frank B Niessen, Steven E R Hovius, Marc A M Mureau
BACKGROUND: Keloids are a burden for patients due to physical, aesthetic and social consequences. Treatment remains a challenge due to therapy resistance and high recurrence rates. The main goals of treatment are to improve scar appearance and symptoms and patients' quality of life (QoL). METHODS: Two multicentre, randomised controlled open trials that compared 1) intralesional cryotherapy with excision and corticosteroid injections for primary keloids, and 2) intralesional cryotherapy with excision and brachytherapy for therapy resistant keloids...
February 6, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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