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Brooks V Udelsman, Jessica Eaton, Ashok Muniappan, Christopher R Morse, Cameron D Wright, Douglas J Mathisen
OBJECTIVE: Patients with complicated airway defects that exceed the limits of primary repair represent a challenging clinical problem and require alternative techniques for repair. The aim of this study was to evaluate bioprosthetic reconstruction of large tracheal and bronchial defects. METHODS: Retrospective chart review of patients treated at a single tertiary center from 2008 to 2015 who underwent repair of tracheal or bronchial defects with a bioprosthetic device, namely aortic homograft or acellular dermal matrix...
November 2016: Journal of Thoracic and Cardiovascular Surgery
M Ogawa, T Fujita, N Fukushima, T Nakatani, S Kitamiura, Y Imamura, K Watanabe, S Iwata, A Kinjo
BACKGROUND: Because tissue transplantation (TTx) has not been familiar to the general public or even to medical staffs in Japan, awareness of TTx is very important to increase tissue donation. Our primary aim was to describe the current status of awareness of TTx in medical staffs and in the general public around Osaka. METHODS: Between July 2014 and February 2015, 1015 general public citizens, 203 medical staff members working in emergency hospitals, and 168 cardiothoracic surgeons were invited to complete a letter or web-based survey through the use of a self-designed questionnaire...
September 2016: Transplantation Proceedings
Jonathan M Philpott, Christian W Zemlin
No abstract text is available yet for this article.
September 17, 2016: Journal of Thoracic and Cardiovascular Surgery
Arindam Choudhury, Rohan Magoon, Poonam Malhotra Kapoor, P Rajashekar
Aortic root surgical anatomy and knowledge of the various homograft implantation techniques is of paramount importance to the attending anesthesiologist for echocardiographic correlation, estimation and accurately predicting aortic annular dimensions for the valve replacement in a case of diseased homograft.
October 2016: Annals of Cardiac Anaesthesia
Kimberly Naden Hollander, Mario Montealegre-Gallegos, Feroze Mahmood
In recent years, the use of transcatheter aortic valve replacement (TAVR) has extended beyond the treatment of native aortic valve stenosis in patients with high surgical risk. TAVR is increasingly being performed for bioprosthetic aortic valve failure, i.e., the valve-in-valve (VIV) procedure. Establishing the success of a VIV procedure can be challenging in these cases. Furthermore, the limited availability of prostheses sizes further complicates the management of these patients. We present an unusual case of a repeat TAVR in a patient who previously had a VIV procedure in an aortic homograft...
October 2016: Annals of Cardiac Anaesthesia
Inês C Mendes, Fernando Maymone-Martins, Rui Anjos
A 30-year-old female with tricuspid valve atresia, ventricular septal defect, and atrial septal defect had a neonatal modified Blalock Taussig shunt and a Fontan-Björk operation performed at five years of age. She did well initially but progressively developed signs of systemic congestion due to severe homograft stenosis and underwent successful percutaneous implantation of a Melody(®) pulmonary valve (Medtronic, Minneapolis, MN, USA) in the "tricuspid" position.
October 4, 2016: Journal of Cardiac Surgery
Pascal M Dohmen, Lukas Lehmkuhl, Michael A Borger, Martin Misfeld, Friedrich W Mohr
BACKGROUND We present a unique case of a 61-year-old female patient with homograft deterioration after redo surgery for prosthetic valve endocarditis with root abscess. CASE REPORT The first operation was performed for type A dissection with root, arch, and elephant trunk replacement of the thoracic aorta. The present re-redo surgery was performed as valve-in-valve with a sutureless aortic bioprosthesis. The postoperative course was uneventful and the patient was discharged on day 6. CONCLUSIONS The current case report demonstrates that sutureless bioprostheses are an attractive option for surgical valve-in-valve procedures, which can reduce morbidity and mortality...
October 3, 2016: American Journal of Case Reports
A Gombert, J Grommes, G Schick, M Binnebösel, C Klink, M J Jacobs, D Kotelis
OBJECTIVE: Aortoesophageal fistulas are rare and life-threatening conditions. Till now, an association between an aortoesophageal fistula and sarcoidoisis has not been reported yet. The aim of this report is to demonstrate a case of aortoesophageal fistula (AEF) secondary to sarcoidosis and its multistage interdisciplinary surgical therapy. CASE REPORT: A 66-year-old male was diagnosed with sarcoidosis in 2014. He has been treated with glucocorticoids since then and no severe health restrictions due the disease had occurred...
September 23, 2016: Annals of Vascular Surgery
Mario Milazzo, Serena Danti, Francesco Inglese, Godfried Jansen van Vuuren, Vera Gramigna, Gabriella Bonsignori, Andrea De Vito, Luca Bruschini, Cesare Stefanini, Stefano Berrettini
This study shows the fabrication of innovative ossicular replacement prostheses (ORPs) based on banked cortical bone using computer numerically controlled ultraprecision micromilling, as a substantial improvement of "second generation" ORPs. Our aim is to combine optimal middle ear compatibility and surgical manageability in a single device, by releasing off-the-shelf homograft ORPs provided with the appealing features of synthetic ORPs, such as lightness, safety, measurement accuracy, surface decoration, and geometric plasticity...
September 23, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Rouven Kubicki, Brigitte Stiller, Jochen Grohmann
Pseudoaneurysm formation is a rare but potentially life-threatening complication after surgical repair of congenital heart disease. We present a boy with truncus arteriosus communis 14 years after homograft placement in pulmonary position. On follow-up, he presented progressive chronic homograft degeneration. Moreover, a large pseudoaneurysm in the right ventricular outflow tract was surprisingly depicted. We opted for a two-stage interventional approach.
2016: SpringerPlus
Julien Guihaire, Martin Kloeckner, Philippe Deleuze
Destructive aortic valve endocarditis is a serious condition that can result in aortoventricular disjunction. The appropriate surgical approach for severe excavating lesions remains a matter of debate. Homografts, prosthetic valves associated with a pericardial patch for annulus repair, and prosthetic valve conduits can be used. We report the technical issue of subcoronary inclusion of the full root Freestyle xenograft for complicated aortic endocarditis extending to the left ventricular outflow tract.
October 2016: Annals of Thoracic Surgery
Tommaso Hinna Danesi, Giuseppe Minniti, Giovanni Domenico Cresce, Alessandro Favaro, Paolo Magagna, Stefano Auriemma, Matteo Micciolo, Salvo Mirone, Elvio Polesel, Loris Salvador
Homograft implantation in the aortic position was a common approach for full root aortic surgical procedures in the early 2000s. Reintervention after degeneration of such homografts remains a challenge. We report two cases of successful implantation of the Edwards Intuity Elite rapid deployment valve into patients with degeneration of existing aortic homograft implants leading to severe aortic regurgitation.
October 2016: Annals of Thoracic Surgery
Hengxing Liang, Wenliang Liu, Sichuang Tan, Fenglei Yu
Aortoesophageal fistula (AEF) is a rare but fatal complication caused by foreign body ingestion. Aortic replacement and endovascular stent graft are the common repair surgeries. The materials to repair an aortic defect in AEF are typically homograft or allograft, but the use of an autologous pericardium patch is rarely reported. Here we reported a patient with AEF and severe mediastinal infection induced by chicken bone ingestion. In this case, the autologous pericardium patch was used as the repair material...
September 28, 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
Piotr Dobrowolski, Mirosław Kowalski, Ilona Michałowska, Piotr Hoffman
No abstract text is available yet for this article.
September 15, 2016: European Journal of Cardio-thoracic Surgery
R C Schoonbeek, P G Pieper, Y J van Slooten, H G Freling, G T Sieswerda, A P J van Dijk, M R M Jongbloed, M C Post, B J Bouma, R M F Berger, T Ebels, J P van Melle
OBJECTIVES: N-terminal B‑type natriuretic peptide (NT-proBNP) is an important biomarker for the detection of heart failure. Adults with congenital heart disease (ACHD) and a prosthetic heart valve are at risk for heart failure. This study aimed to determine the value of NT-proBNP in ACHD patients with a prosthetic valve and investigate its relationship with cardiac function and exercise capacity. METHODS: In this multi-centre cross-sectional observational study, data regarding medical history, echocardiography, exercise testing (VO2peak) and laboratory blood evaluation (including NT-proBNP) were collected in ACHD patients with a single prosthetic valve (either homografts, heterografts or mechanical valves)...
November 2016: Netherlands Heart Journal
Danae Simone Genevieve Paultre, Marie-Paule Gustin, Attila Molnar, Karl J Oparka
In addition to moving sugars, and nutrients, the phloem transports many macromolecules. While grafting and aphid stylectomy experiments have identified many macromolecules that move in the phloem, the functional significance of phloem transport of these remains unclear. To gain insight into protein trafficking, we micrografted Arabidopsis thaliana scions expressing GFP-tagged chloroplast transit peptides under the 35S promoter onto non-transgenic rootstocks. We found that plastids in the root tip became fluorescent 10 days after grafting...
September 6, 2016: Plant Cell
Richard A Jonas
The author's approach to the management of tetralogy of Fallot with absent pulmonary valve is described, including the technique of homograft replacement of the central pulmonary arteries for the neonate who presents with profound respiratory compromise.
September 2016: World Journal for Pediatric & Congenital Heart Surgery
José G Díez, Michael Schechter, Kathryn G Dougherty, Ourania Preventza, Joseph S Coselli
Transcatheter aortic valve replacement (TAVR) is a well-established method for replacing native aortic valves; however, it was conceived for elderly patients with aortic valve stenosis, and the lack of data on long-term durability has led practitioners to restrict the use of TAVR to patients who have short life expectancies. Here, we describe the case of a 21-year-old woman who had undergone 3 previous open aortic valve replacements and who presented with symptoms of recurrent valvular failure. Transthoracic echocardiograms and computed tomographic angiograms revealed a degenerating aortic root homograft with substantial calcification, moderate-to-severe aortic valve stenosis, and severe aortic valve regurgitation...
August 2016: Texas Heart Institute Journal
Julius I Ejiofor, Maroun Yammine, Morgan T Harloff, Siobhan McGurk, Jochen D Muehlschlegel, Prem S Shekar, Lawrence H Cohn, Pinak Shah, Tsuyoshi Kaneko
BACKGROUND: Bioprosthetic aortic valve use has increased steadily according to The Society of Thoracic Surgeons (STS) database analyses. One of the momentums toward this trend is the future utilization of transcatheter valve-in-valve (TViV) techniques when bioprosthetic valves fail. We compared the results of reoperative TViV to surgical aortic valve replacement (SAVR) for degenerated bioprosthetic valves. METHODS: From January 2002 to January 2015, we identified 91 patients with degenerated bioprosthetic valves who underwent isolated AVR (SAVR n = 69, TViV n = 22)...
August 12, 2016: Annals of Thoracic Surgery
Joo Yeon Kim, Joon Bum Kim, Sung-Ho Jung, Suk Jung Choo, Cheol Hyun Chung, Jae Won Lee
BACKGROUND: The advantages of using a homograft in valve replacement surgery are the excellent hemodynamic profile, low risk of thromboembolism, and low risk of prosthetic valve infection. The aim of this study was to evaluate the long-term outcomes of homograft implantation in the aortic valve position. METHODS: This is a retrospective study of 33 patients (>20 years old) who underwent aortic valve replacement or root replacement with homografts between April 1995 and May 2015...
August 2016: Korean Journal of Thoracic and Cardiovascular Surgery
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