keyword
MENU ▼
Read by QxMD icon Read
search

Homografts

keyword
https://www.readbyqxmd.com/read/29327146/mid-term-outcome-of-100-consecutive-ross-procedures-excellent-survival-but-yet-to-be-a-cure
#1
Corina Zimmermann, Christine Attenhofer Jost, René Prêtre, Christoph Mueller, Matthias Greutmann, Burkhardt Seifert, Emanuela Valsangiacomo Büchel, Oliver Kretschmar, Hitendu Hasmukhlal Dave, Roland Weber
The Ross procedure offers excellent short-term outcome but the long-term durability is under debate. Reinterventions and follow-up of 100 consecutive patients undergoing Ross Procedure at our centre (1993-2011) were analysed. Follow-up was available for 96 patients (97%) with a median duration of 5.3 (0.1-17.1) years. Median age of the patient cohort was 15.2 (0.04-58.4) years with 76 males. 93% had underlying congenital aortic stenosis. Root replacement technique was applied in all. The most common valved conduits used for reconstruction of the right ventricular outflow tract were homografts (66 patients) and bovine jugular vein (ContegraR) graft (31 patients)...
January 12, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29310558/surgical-palliation-of-right-aortic-arch-with-an-isolated-innominate-artery-from-the-left-ductus-arteriosus
#2
Matthew C Schwartz, Kamal Pourmoghadam, Michael O'Brien, Craig E Fleishman, William DeCampli
A right aortic arch with an isolated left innominate artery from the left patent ductus arteriosus is a rare arch anomaly, and establishing continuity between the innominate artery and aorta can be challenging. We describe repair of this lesion in a three-week-old male using an autologous pedicle flap of ascending aorta as well as a homograft patch as the roof to recreate continuity between the aorta and left innominate artery.
January 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29288660/novel-treatment-of-a-degenerated-bioroot-with-the-use-of-the-sutureless-valve-technique
#3
Thijs Stoker, Ahmed Mashhour, Jerry Easo, Kay Kronberg, Jürgen Ennker, Alexander Weymann
We describe three patients with severe aortic regurgitation after aortic root replacement using the Medtronic Freestyle® bioprosthesis. In two cases, the indication was endocarditis. The third case showed rupture of the right coronary cusp. To achieve fewer complications, lower operative risk and save operative and cross-clamp times, implantation of a sutureless bioprosthesis in a valve-in-valve manner was performed. In two cases, a Perceval bioprosthesis and in the other case, a 3f-Enable bioprosthesis were used...
December 27, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29248123/current-management-of-infected-aortic-grafts-in-patients-with-connective-tissue-disorders
#4
REVIEW
Natalia O Glebova, James H Black
Patients with connective tissue disorder present a particular clinical challenge in the treatment of aortic graft infections. Specific complexities arise in patients with connective tissue disorders when reoperation for aortic graft infection is required. Herein we describe current management of infected aortic grafts in patients with connective tissue disorders using homograft and rifampin-coated graft replacements using in situ replacement therapy, which is associated with improved outcome compared to graft excision and extra-anatomic bypass...
June 2017: Seminars in Vascular Surgery
https://www.readbyqxmd.com/read/29234609/outcomes-of-open-repair-of-mycotic-aortic-aneurysms-with-in-situ-replacement
#5
Hyo-Hyun Kim, Do Jung Kim, Hyun-Chel Joo
Background: Mycotic aortic aneurysms are rare and life-threatening. Unfortunately, no established guidelines exist for the treatment of patients with mycotic aortic aneurysms. The purpose of this study was to evaluate the midterm outcomes of the open repair of mycotic thoracic and thoracoabdominal aneurysms and suggest a therapeutic strategy. Methods: From 2006 to 2016, 19 patients underwent open repair for an aortic aneurysm. All infected tissue was extensively debrided and covered with soft tissue...
December 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29223842/interstage-evaluation-of-homograft-valved-right-ventricle-to-pulmonary-artery-conduits-for-palliation-of-hypoplastic-left-heart-syndrome
#6
Nefthi Sandeep, Rajesh Punn, Sowmya Balasubramanian, Shea N Smith, Olaf Reinhartz, Yulin Zhang, Gail E Wright, Lynn F Peng, Lisa Wise-Faberowski, Frank L Hanley, Doff B McElhinney
OBJECTIVE: Palliation of hypoplastic left heart syndrome with a standard nonvalved right ventricle to pulmonary artery conduit results in an inefficient circulation in part due to diastolic regurgitation. A composite right ventricle pulmonary artery conduit with a homograft valve has a hypothetical advantage of reducing regurgitation, but may differ in the propensity for stenosis because of valve remodeling. METHODS: This retrospective cohort study included 130 patients with hypoplastic left heart syndrome who underwent a modified stage 1 procedure with a right ventricle to pulmonary artery conduit from 2002 to 2015...
November 8, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29222866/outcome-of-antibody-mediated-rejection-compared-to-acute-cellular-rejection-after-pediatric-heart-transplantation
#7
Gabrielle R Vaughn, Neal W Jorgensen, Yuk M Law, Erin L Albers, Borah J Hong, Joshua M Friedland-Little, Mariska S Kemna
Outcomes of ACR after pediatric HTx have been well described, but less has been reported on outcomes of AMR. We compared the clinical characteristics and cardiovascular outcomes (composite end-point of death, retransplantation, or allograft vasculopathy) of pediatric HTx recipients with AMR, ACR, and no rejection in a retrospective single-center study of 104 recipients. Twenty were treated for AMR; 15 were treated for ACR. Recipients with AMR had an increased frequency of congenital heart disease (90% vs ACR 67% vs no rejection 59%, P = ...
December 9, 2017: Pediatric Transplantation
https://www.readbyqxmd.com/read/29208581/how-should-i-treat-a-left-persistent-superior-vena-cava-with-unroofed-coronary-sinus-associated-with-severe-stenosis-and-regurgitation-of-aortic-homograft-placed-in-the-tricuspid-position
#8
Valeria Pergola, Giovanni Di Salvo, Mohammed Al-Admawi, Bahaa Fadel, Mansour Al-Jufan, Massimo Chessa, Jonathan McGuinness
No abstract text is available yet for this article.
December 8, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29186380/impact-of-t-cell-mediated-immune-response-on-xenogeneic-heart-valve-transplantation-short-term-success-and-mid-term-failure
#9
Anna C Biermann, Julia Marzi, Eva Brauchle, Maria Schneider, Angela Kornberger, Sherif Abdelaziz, Julian L Wichmann, Christophe T Arendt, Eike Nagel, Kelvin G M Brockbank, Martina Seifert, Katja Schenke-Layland, Ulrich A Stock
OBJECTIVES: Allogeneic frozen cryopreserved heart valves (allografts or homografts) are commonly used in clinical practice. A major obstacle for their application is the limited availability in particular for paediatrics. Allogeneic large animal studies revealed that alternative ice-free cryopreservation (IFC) results in better matrix preservation and reduced immunogenicity. The objective of this study was to evaluate xenogeneic (porcine) compared with allogeneic (ovine) IFC heart valves in a large animal study...
November 27, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29164158/development-of-multiple-aortic-mycotic-aneurysms-after-cardiac-catheterization
#10
Desiree A Steimer, John J Squiers, J Michael DiMaio, Katherine B Harrington
A 71-year-old male with a past medical history of coronary artery bypass surgery developed multiple, infected pseudoaneurysms of the ascending aorta and aortic root 1 year after cardiac catheterization. He underwent aortic root replacement with a 24-mm homograft. Tissue culture from operative specimens revealed invasive Aspergillus fumigatus infection. He was treated with voriconazole for 3 months. After 1 year, he had no recurrence of symptoms, pseudoaneurysm, or fungal infection.
October 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29127746/-surgical-treatment-of-aortic-root-aneurysm-comparison-of-bentall-procedure-and-david-reimplantation-of-aortic-valve
#11
Jiří Ničovský, Jiří Ondrášek, Jan Černý, Daniela Žáková, Petr Němec
INTRODUCTION: The aortic root aneurysm is associated with a more frequent occurrence of aortic dissection and development of aortic regurgitation. The aim of this study was to compare outcomes of composite graft replacement and valve sparing root replacement in treating aortic root aneurysms. METHODS: From January 2006 to December 2015 a total of 137 patients (mean age 46.3 ± 14.5, range 16-65) underwent elective surgery for aortic root aneurysm without valvular structural defects...
2017: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29108244/tipe1-function-as-a-prognosis-predictor-and-negative-regulator-of-lung-cancer
#12
Xiaocheng Wu, Yunmiao Ma, Ji Cheng, Xia Li, Hui Zheng, Li Jiang, Renjie Zhou
TIPE1 (tumor necrosis factor-α-induced protein 8-like 1 or TNFAIP8L1) belongs to the TIPE (TNFAIP8) family, which act as a regulator of cell death. However, the expression and biologic functions of TIPE1 in lung cancer are largely unknown. Here, we investigated the roles of TIPE1 in lung cancer. Evaluated by qRT-PCR and immunohistochemical staining, lower TIPE1 mRNA and protein expression was found in the lung tumor tissue, compared with adjacent non-tumor tissues, which positively correlated with tumor patient survival...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29078248/-management-of-endograft-infection-after-evar-and-tevar-a-case-series-and-literature-review
#13
Thomas Betz, Ingolf Töpel, Markus Steinbauer, Christian Uhl
Introduction Endograft infection after EVAR (Endovascular aortic repair) or TEVAR (Thoracic endovascular aortic repair) is a rare but severe complication with high mortality. As the number of patients with endovascular aneurysm repair has increased over the last decade, the number of patients with endograft infection might also have increased. However, no guideline defines the treatment of endograft infection. Diagnosis is difficult and depends on clinical symptoms, radiological imaging and blood cultures. Surgery with graft excision, debridement and revascularisation should be proposed...
October 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/29050225/hcarg-commd5-inhibits-erbb-receptor-driven-renal-cell-carcinoma
#14
Hiroyuki Matsuda, Carole G Campion, Kyoko Fujiwara, Jin Ikeda, Suzanne Cossette, Thomas Verissimo, Maiko Ogasawara, Louis Gaboury, Kosuke Saito, Kenya Yamaguchi, Satoru Takahashi, Morito Endo, Noboru Fukuda, Masayoshi Soma, Pavel Hamet, Johanne Tremblay
Hypertension-related, calcium-regulated gene (HCaRG/COMMD5) is highly expressed in renal proximal tubules, where it contributes to the control of cell proliferation and differentiation. HCaRG accelerates tubular repair by facilitating re-differentiation of injured proximal tubular epithelial cells, thus improving mouse survival after acute kidney injury. Sustained hyper-proliferation and de-differentiation are important hallmarks of tumor progression. Here, we demonstrate that cancer cells overexpressing HCaRG maintain a more differentiated phenotype, while several of them undergo autophagic cell death...
September 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/29049550/mid-term-outcomes-of-congenital-mitral-valve-surgery-shone-s-syndrome-is-a-risk-factor-for-death-and-reintervention
#15
Koichi Sughimoto, Igor E Konstantinov, Yves d'Udekem, Johann Brink, Diana Zannino, Christian P Brizard
OBJECTIVES: To study the recent trends and outcomes of congenital mitral valve surgery in children. METHODS: From 2008 to 2014, 84 procedures in 66 consecutive patients (41 procedures in 31 patients with mitral stenosis and 43 procedures in 35 patients with mitral regurgitation) were retrospectively evaluated. The mean age at surgery was 4.3 ± 5.4 years, and 27 patients (41%) were neonates or infants. RESULTS: Seven (11%) patients died during the follow-up period of 3...
November 1, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29029050/small-sized-conduits-in-the-right-ventricular-outflow-tract-in-young-children-bicuspidalized-homografts-are-a-good-alternative-to-standard-conduits
#16
Katrien François, Katya De Groote, Kristof Vandekerckhove, Hans De Wilde, Daniel De Wolf, Thierry Bové
OBJECTIVES: Downsizing a homograft (HG) through bicuspidalization has been used for more than 2 decades to overcome the shortage of small-sized conduits for reconstruction of the right ventricular outflow tract (RVOT) in young children. Our goal was to investigate the durability of bicuspidalized HGs compared with other small HGs. METHODS: A retrospective analysis of 93 conduits ≤20 mm, implanted over 23 years, was performed. The end-points were survival, structural valve degeneration and conduit replacement...
October 3, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29029030/outcomes-of-surgery-for-infective-endocarditis-a-single-centre-experience-of-801-patients
#17
Sameh M Said, Zaid M Abdelsattar, Hartzell V Schaff, Kevin L Greason, Richard C Daly, Alberto Pochettino, Lyle D Joyce, Joseph A Dearani
OBJECTIVES: Infective endocarditis (IE) remains a life-threatening disease, despite the improvement in diagnostic and therapeutic measures. We reviewed our outcomes for all adults who underwent surgery for endocarditis at our centre. METHODS: Between January 1995 and December 2013, 801 patients [586 men (73%)] underwent surgery for IE. Mean age was 60 ± 14.7 years. Native endocarditis (NE) was present in 372 patients (46%), and 379 (47%) patients had active IE...
October 3, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29027509/multiply-adjusted-comparisons-a-meta-analysis-method-to-compare-single-arm-clinical-trial-data-to-literature-results-regarding-a-competitor
#18
Dietmar Boethig, Hartmut Hecker
Prospective randomized controlled trials are difficult to obtain if a promising new therapy has to be tested against seemingly obsolete alternatives. One method to address this problem is to compare the results of (multicentre) trials to literature results. However, previous treatment-era changes and population-dependent results complicate objective comparisons. The presented approach describes a method to objectify such comparisons in cases in which individual raw data regarding a new therapy have to be compared to summary results regarding a conventional alternative published in the literature...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/28987279/long-term-evaluation-of-the-ross-procedure-in-acute-infective-endocarditis
#19
Thomas Ratschiller, Sames-Dolzer Eva, Patrick Paulus, Wolfgang Schimetta, Hannes Müller, Andreas F Zierer, Rudolf Mair
OBJECTIVE: Optimal valve substitute for young patients with aortic valve endocarditis remains controversial. Given its better resistance to infection, the Ross procedure is an attractive alternative to prosthetic valve replacement or homograft implantation. The objective of this study was to assess long-term outcomes of the Ross procedure in this indication. METHODS: From 01/1991 to 04/2017, 190 patients underwent a Ross procedure at our institution. Acute endocarditis was the indication for operation in 19 patients, including 6 patients with a bicuspid aortic valve...
October 5, 2017: Seminars in Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28974283/is-mesocardia-with-left-sided-caval-vein-draining-to-coronary-sinus-a-contraindication-for-a-percutaneous-pulmonary-valve-implantation-a-case-description
#20
Marinos Kantzis, Christoph M Happel, Nikolaus A Haas
Introduction Although the right jugular vein approach for percutaneous pulmonary valve implantation is well described, there are no reports that describe a percutaneous pulmonary valve implantation through a left superior caval vein to coronary sinus pathway. Case A 14-year-old female with tetralogy of Fallot, mesocardia, left superior caval vein draining into the coronary sinus, and hemiazygos continuation of the inferior caval vein underwent ventricular septal defect closure, with homograft insertion from the right ventricle to the pulmonary artery, patch augmentation of the left pulmonary artery, and creation of an atrial communication...
October 4, 2017: Cardiology in the Young
keyword
keyword
62630
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"