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https://www.readbyqxmd.com/read/28919137/pseudoaneurysm-complicating-right-ventricle-to-pulmonary-artery-conduit-surgery-incidence-and-risk-factors
#1
Michelle C Sykes, Meena Nathan, Stephen P Sanders, Kimberlee Gauvreau, Frank A Pigula, Jonathan Rhodes
OBJECTIVES: Although pseudoaneurysm is an uncommon complication after right ventricle-to-pulmonary artery conduit placement, it has the potential to cause significant morbidity and mortality. METHODS: We performed a review of patients with pseudoaneurysms diagnosed at our institution in a 20-year period (from 1995 through 2015) and compared their clinical characteristics with a group of age- and sex-matched control patients. RESULTS: We found that younger age, smaller size, the diagnosis of tetralogy of Fallot, the use of a pulmonary homograft conduit, the presence of an unrestrictive ventricular septal defect after conduit placement, and having at least systemic right ventricular pressure were all more common in patients who had pseudoaneurysms develop...
August 24, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28894378/initial-experience-of-correlating-diffusion-spectral-parameters-with-histopathologic-indexes-in-murine-colorectal-tumor-homografts
#2
Xiao-Yan Zhang, Xiao-Ting Li, Jia Sun, Ying-Shi Sun
PURPOSE: To determine the correlation between continuously distributed diffusion-weighted image (DWI)-derived parameters and histopathologic indexes. METHODS: Fifty-four mice bearing HCT-116 colorectal tumors were included for analysis; 12 mice were used for continuous observation, and the other 42 mice were used for break-point observation. All mice were randomly divided into radiotherapy and non-radiotherapy groups. Optical imaging and MRI were performed at different time points according to radiotherapy regimen (baseline, 24 h, 48 h, 72 h, 7 d, 14 d, and 28 d)...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/28894059/-re-operation-for-saccular-aneurysm-after-ascending-aortic-replacement-with-homograft-report-of-a-case
#3
Masahiro Ikeda, Toshihisa Asakura, Kazuhiko Uwabe, Kozo Morita, Atsushi Iguchi, Hiroshi Niinami
A 62-years-old female had undergone ascending aortic replacement with homograft for graft infection and mediastinitis after initial replacement of ascending aorta due to acute type A dissection. Ten years after homograft replacement, follow up computed tomography showed acute growing saccular aneurysm of the homograft without infectious symptoms. We urgently performed Bentall procedure and hemiarch replacement successfully. Pathological diagnosis was true aneurysm of the homograft. She was discharged from hospital without any complication and has been quite uneventful 7 years after surgery...
September 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28882144/sutureless-aortic-valve-replacement-in-a-calcified-homograft-combined-with-mitral-valve-replacement
#4
Ferdi Akca, Kayan Lam, Ibrahim Özdemir, Erwin Tan
BACKGROUND: Aortic valve replacement in a patient with an aortic homograft can be very challenging, especially when concomitant mitral valve surgery needs to be performed. CASE PRESENTATION: We report a case of implantation of a sutureless aortic valve bioprosthesis combined with mitral valve replacement in a patient with a severely calcified aortic homograft where conventional valve replacement was technically unfeasible. CONCLUSIONS: We believe that sutureless AVR is a viable option especially for young patients with a high surgical risk where conventional valve replacement cannot be achieved...
September 7, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28793902/30-year-experience-of-fontan-surgery-single-centre-s-data
#5
Laurynas Bezuska, Virgilijus Lebetkevicius, Rita Sudikiene, Daina Liekiene, Virgilijus Tarutis
BACKGROUND: The Fontan procedure has been modified several times since it was introduced into practice in 1968. As many patients now survive to adulthood, attention is directed towards their clinical status and late morbidity. We report our surgical experience of 30 years in Fontan procedures. METHODS: From January 1985 to January 2015, 80 patients underwent Fontan surgery. Twenty-one patients received an atrio-pulmonary Fontan (Group I), four patients underwent total cavopulmonary connection (TCPC) with an intra-atrial lateral tunnel (Group II), six patients received extra-cardiac TCPC with an aortic homograft (group III) and 49 patients received extra-cardiac TCPC with an expanded polytetrafluoroethylene conduit...
August 9, 2017: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28775235/tipe1-function-as-a-prognosis-predictor-and-negative-regulator-of-lung-cancer
#6
Xiaocheng Wu, Yunmiao Ma, Ji Cheng, Xia Li, Hui Zheng, Li Jiang, Renjie Zhou
TIPE1 (tumor necrosis factor-α-induced protein 8-like 1 or TNFAIP8L1) belongs to the TIPE (TNFAIP8) family, which act as a regulator of cell death. However, the expression and biologic functions of TIPE1 in lung cancer are largely unknown. Here, we investigated the roles of TIPE1 in lung cancer. Evaluated by qRT-PCR and immunohistochemical staining, lower TIPE1 mRNA and protein expression was found in the lung tumor tissue, compared with adjacent non-tumor tissues, which positively correlated with tumor patient survival...
July 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28766119/professor-yves-goffin-m-d-ph-d-the-founder-of-the-european-homograft-bank-ehb-past-away
#7
Ramadan Jashari, Béatrice Van Hoeck
No abstract text is available yet for this article.
August 1, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28753691/experimental-study-of-anisotropic-stress-strain-relationships-of-aortic-and-pulmonary-artery-homografts-and-synthetic-vascular-grafts
#8
Yueqian Jia, Yangyang Qiao, I Ricardo Argueta-Morales, Aung Maung, Jack Norfleet, Yuanli Bai, Eduardo Divo, Alain J Kassab, William M DeCampli
Homografts and synthetic grafts are used in surgery for congenital heart disease (CHD). Determining these materials' mechanical properties will aid in understanding tissue behavior when subjected to abnormal CHD hemodynamics. Homograft tissue samples from anterior/posterior aspects, of ascending/descending aorta (AA, DA), innominate artery (IA), left subclavian artery (LScA), left common carotid artery (LCCA), main/left/right pulmonary artery (MPA, LPA, RPA), and synthetic vascular grafts, were obtained in three orientations: circumferential, diagonal (45 deg relative to circumferential direction), and longitudinal...
October 1, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28735512/balloon-dilatation-of-homograft-conduits-in-the-pulmonary-position-delays-re-intervention
#9
Hye-In Jeong, Jinyoung Song, Hyelim Lee, Jun Huh, I-Seok Kang
No abstract text is available yet for this article.
October 2017: Minerva Chirurgica
https://www.readbyqxmd.com/read/28734430/transcatheter-aortic-valve-implantation-under-direct-visualization-in-homograft-valve-endocarditis
#10
Tarek Chami, Guilherme Attizzani, Benjamin Medalion, Salil V Deo
Prosthetic valve endocarditis is a very grave and often terminal disease. Surgical valve replacement remains the cornerstone treatment for this disease. However, it is often contraindicated. Herein, we describe the implantation under direct visualization of a self-expandable transcatheter heart valve in a prohibitive surgical risk patient with homograft aortic valve endocarditis.
August 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28712577/bacterial-adherence-to-graft-tissues-in-static-and-flow-conditions
#11
Tiago Rafael Veloso, Jorien Claes, Soetkin Van Kerckhoven, Bartosz Ditkowski, Luis G Hurtado-Aguilar, Stefan Jockenhoevel, Petra Mela, Ramadan Jashari, Marc Gewillig, Marc F Hoylaerts, Bart Meyns, Ruth Heying
BACKGROUND: Various conduits and stent-mounted valves are used as pulmonary valve graft tissues for right ventricular outflow tract reconstruction with good hemodynamic results. Valve replacement carries an increased risk of infective endocarditis (IE). Recent observations have increased awareness of the risk of IE after transcatheter implantation of a stent-mounted bovine jugular vein valve. This study focused on the susceptibility of graft tissue surfaces to bacterial adherence as a potential risk factor for subsequent IE...
June 16, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28642109/neoaortic-xenoprosthetic-grafts-for-treatment-of-mycotic-aneurysms-and-infected-aortic-grafts
#12
Chukwudubem Anibueze, Visesh Sankaran, Umar Sadat, Kelvin Tan, Yvonne G Wilson, Robert E Brightwell, Michael S Delbridge, Philip W Stather
BACKGROUND: There is no international consensus regarding the optimum management of infected aortae (mycotic aneurysms, infected aortic grafts). Neoaortoiliac reconstruction has advantages over extra-anatomical bypass grafting; however, the use of autologous vein is associated with venous hypertension and compartment syndrome, alternatively cadaveric homografts are associated with high rates of perianastomotic hemorrhage, limb occlusion, and pseudoaneurysm. Arterial repair using xenoprosthetic patches is associated with lower infection rates compared to the use of prosthetic material...
June 20, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28638079/transcriptome-changes-between-compatible-and-incompatible-graft-combination-of-litchi-chinensis-by-digital-gene-expression-profile
#13
Zhe Chen, Jietang Zhao, Fuchu Hu, Yonghua Qin, Xianghe Wang, Guibing Hu
Plant grafting has been practiced widely in horticulture and proved as a useful tool in science. However, the mechanisms of graft healing or graft incompatibility remain poorly understood. In this study, Litchi chinensis cv. 'Jingganghongnuo' homograft ('J/J') and 'Jingganghongnuo'/'zhuangyuanhong' heterograft ('J/Z') as compatible and incompatible combination, respectively, was used to study transcriptional changes between incompatible and compatible graft during graft union formation. Anatomical observation indicated that three stages (2 h, 14 d and 21 d after grafting) were critical for graft union formation and selected for high-throughput sequencing...
June 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28616341/ascending-aorta-reinterventions
#14
REVIEW
Jacobo Silva Guisasola, Rubén Alvarez-Cabo, Daniel Hernández-Vaquero, Rocío Díaz Méndez
Ascending aorta reinterventions present a challenge for surgeons as the technical difficulties of the procedure and the complex strategic approach can complicate successful treatment. These patients should be treated by surgical teams with ample experience in aortic diseases as they can be at high risk of mortality. The number of interventions on the ascending aorta and aortic arch and the use of biological conducts (lung autograft, homograft, etc.) have increased in recent years; therefore, the number of reinterventions can also be expected to increase, representing 10% of aortic surgical procedures...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28590920/hcarg-commd5-inhibits-erbb-receptor-driven-renal-cell-carcinoma
#15
Hiroyuki Matsuda, Carole G Campion, Kyoko Fujiwara, Jin Ikeda, Suzanne Cossette, Thomas Verissimo, Maiko Ogasawara, Louis Gaboury, Kosuke Saito, Kenya Yamaguchi, Satoru Takahashi, Morito Endo, Noboru Fukuda, Masayoshi Soma, Pavel Hamet, Johanne Tremblay
Hypertension-related, calcium-regulated gene (HCaRG/COMMD5) is highly expressed in renal proximal tubules, where it contributes to the control of cell proliferation and differentiation. HCaRG accelerates tubular repair by facilitating re-differentiation of injured proximal tubular epithelial cells, thus improving mouse survival after acute kidney injury. Sustained hyper-proliferation and de-differentiation are important hallmarks of tumor progression. Here, we demonstrate that cancer cells overexpressing HCaRG maintain a more differentiated phenotype, while several of them undergo autophagic cell death...
May 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28570525/full-root-aortic-valve-replacement-by-stentless-aortic-xenografts-in-patients-with-small-aortic-roots
#16
Reza Tavakoli, Peiman Jamshidi, Max Gassmann
In patients with small aortic roots who need an aortic valve replacement with biological valve substitutes, the implantation of the stented pericardial valve might not meet the functional needs. The implantation of a too-small stented pericardial valve, leading to an effective orifice area indexed to a body surface area less than 0.85 cm(2)/m(2), is regarded as prosthesis-patient mismatch (PPM). A PPM negatively affects the regression of left ventricular hypertrophy and thus the normalization of left ventricular function and the alleviation of symptoms...
May 21, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28570342/the-perceval-sutureless-aortic-valve-review-of-outcomes-complications-and-future-direction
#17
Ramsey Powell, Marc P Pelletier, Michael W A Chu, Denis Bouchard, Kevin N Melvin, Corey Adams
Surgical aortic valve replacement with a stented prosthesis has been the standard of care procedure for aortic stenosis. The Perceval (LivaNova, London, United Kingdom) is a sutureless aortic valve bioprosthesis currently implanted in more than 20,000 patients. The purpose of this article was to review the literature available after 9 years of clinical experience of the Perceval aortic valve. PubMED, Embase, and the Cochrane Library databases were searched. A meta-analysis of summary statistics from individual studies was conducted...
May 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/28503338/infrarenal-infected-aortic-aneurysm-caused-by-streptococcus-pyogenes
#18
Floryn Cherbanyk, Markus Menth, Bernhard Egger, Véronique Erard
Infectious aneurysm is a rare entity associated with significant morbidity and mortality. Current knowledge on pathogenesis, outcome, diagnosis, management, and follow-up remains debatable. We report the case of a patient with Streptococcus pyogenes aneurysm who was successfully treated with a homograft implant and discuss microbiological characteristics, diagnostic methods, and treatment options currently available for this serious disease.
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28481635/heterotopic-implantation-of-decellularized-pulmonary-artery-homografts-in-a-rodent-model-technique-description-and-preliminary-report
#19
Arben Dedja, Massimo A Padalino, Mila Della Barbera, Cosimo Rasola, Paola Pesce, Anna Milan, Michela Pozzobon, David Sacerdoti, Gaetano Thiene, Giovanni Stellin
PURPOSE: Despite a substantial amount of literature on tissue-guided regeneration, decellularization process, repopulation time points and stem cell turnover, more in-depth study on the argument is required. Currently, there are plenty of reports involving large animals, as well as clinical studies facing cardiac repair with decellularized homografts, but no exhaustive rodent models are described. The purpose of this study was to develop such a model in rats; preliminary results are also herein reported...
May 8, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28472474/the-ordeal-of-left-atrioventricular-valve-replacement-in-children-under-1-year-of-age%C3%A2
#20
Elie B Sawan, Johann Brink, Jerome Soquet, Matt Liava'A, Christian P Brizard, Igor E Konstantinov, Yves d'Udekem
OBJECTIVES: This study reviews the outcomes of children under 1 year of age who had left atrioventricular valve (LAVV) replacement (LAVVR) in one centre and explores the benefits of an innovative approach for LAVVR in very small patients. METHODS: Thirteen consecutive patients operated for LAVV replacement between 1997 and 2016 were reviewed retrospectively. Indication for surgery was regurgitation in 7, stenosis in 5 and both stenosis and regurgitation in 1. Nine patients (69%) had previous LAVV repair...
May 2, 2017: Interactive Cardiovascular and Thoracic Surgery
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