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https://www.readbyqxmd.com/read/28318650/the-distribution-of-vascular-endothelial-growth-factor-in-human-meniscus-and-a-meniscal-injury-model
#1
Zhichao Lu, Takayuki Furumatsu, Masataka Fujii, Ami Maehara, Toshifumi Ozaki
BACKGROUND: The meniscus plays an important role in controlling the complex biomechanics of the knee. Meniscus injury is common in the knee joint. The perimeniscal capillary plexus supplies the outer meniscus, whereas the inner meniscus is composed of avascular tissue. Angiogenesis factors, such as vascular endothelial growth factor (VEGF), have important roles in promoting vascularization of various tissues. VEGF-mediated neovascularization is beneficial to the healing of injured tissues...
March 15, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28314900/bony-landmark-between-the-attachment-of-the-medial-meniscus-posterior-root-and-the-posterior-cruciate-ligament-ct-and-mr-imaging-assessment
#2
Masataka Fujii, Takayuki Furumatsu, Shinichi Miyazawa, Yuya Kodama, Tomohito Hino, Yusuke Kamatsuki, Toshifumi Ozaki
OBJECTIVES: (1) To reveal the prevalence of the bony recess (posterior dimple) and (2) to determine the position of the posterior dimple on the tibial plateau using three-dimensional computed tomography (3DCT). MATERIALS AND METHODS: In this study, a retrospective review of 112 patients was performed to identify the posterior dimple and to evaluate its position on 3DCT. Magnetic resonance images (MRIs) were also used to determine the positional relationship among the posterior cruciate ligament (PCL), medial meniscus posterior insertion (MMPI), and posterior dimple...
March 18, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/28302344/comparison-of-weighed-food-record-procedures-for-the-reference-methods-in-two-validation-studies-of-food-frequency-questionnaires
#3
Yuri Ishii, Junko Ishihara, Ribeka Takachi, Yurie Shinozawa, Nahomi Imaeda, Chiho Goto, Kenji Wakai, Toshiaki Takahashi, Hiroyasu Iso, Kazutoshi Nakamura, Junta Tanaka, Taichi Shimazu, Taiki Yamaji, Shizuka Sasazuki, Norie Sawada, Motoki Iwasaki, Haruo Mikami, Kiyonori Kuriki, Mariko Naito, Naoko Okamoto, Fumi Kondo, Satoyo Hosono, Naoko Miyagawa, Etsuko Ozaki, Sakurako Katsuura-Kamano, Keizo Ohnaka, Hinako Nanri, Noriko Tsunematsu-Nakahata, Takamasa Kayama, Ayako Kurihara, Shiomi Kojima, Hideo Tanaka, Shoichiro Tsugane
BACKGROUND: Although open-ended dietary assessment methods, such as weighed food records (WFRs), are generally considered to be comparable, differences between procedures may influence outcome when WFRs are conducted independently. In this paper, we assess the procedures of WFRs in two studies to describe their dietary assessment procedures and compare the subsequent outcomes. METHODS: WFRs of 12 days (3 days for four seasons) were conducted as reference methods for intake data, in accordance with the study protocol, among a subsample of participants of two large cohort studies...
March 13, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28295912/training-with-a-balance-exercise-assist-robot-is-more-effective-than-conventional-training-for-frail-older-adults
#4
Kenichi Ozaki, Izumi Kondo, Satoshi Hirano, Hitoshi Kagaya, Eiichi Saitoh, Aiko Osawa, Yoichi Fujinori
AIM: To examine the efficacy of postural strategy training using a balance exercise assist robot (BEAR) as compared with conventional balance training for frail older adults. METHODS: The present study was designed as a cross-over trial without a washout term. A total of 27 community-dwelling frail or prefrail elderly residents (7 men, 20 women; age range 65-85 years) were selected from a volunteer sample. Two exercises were prepared for interventions: robotic exercise moving the center of gravity by the balance exercise assist robot system; and conventional balance training combining muscle-strengthening exercise, postural strategy training and applied motion exercise...
March 10, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/28295574/cd38-positively-regulates-postnatal-development-of-astrocytes-cell-autonomously-and-oligodendrocytes-non-cell-autonomously
#5
Tsuyoshi Hattori, Minoru Kaji, Hiroshi Ishii, Roboon Jureepon, Mika Takarada-Iemata, Hieu Minh Ta, Thuong Manh Le, Ayumu Konno, Hirokazu Hirai, Yoshitake Shiraishi, Noriyuki Ozaki, Yasuhiko Yamamoto, Hiroshi Okamoto, Shigeru Yokoyama, Haruhiro Higashida, Yasuko Kitao, Osamu Hori
Glial development is critical for the function of the central nervous system. CD38 is a multifunctional molecule with ADP-ribosyl cyclase activity. While critical roles of CD38 in the adult brain such as oxytocin release and social behavior have been reported, those in the developing brain remain largely unknown. Here we demonstrate that deletion of Cd38 leads to impaired development of astrocytes and oligodendrocytes in mice. CD38 is highly expressed in the developing brains between postnatal day 14 (P14) and day 28 (P28)...
March 13, 2017: Glia
https://www.readbyqxmd.com/read/28295338/modified-transnasal-endoscopic-medial-maxillectomy-through-prelacrimal-duct-approach
#6
Motohiko Suzuki, Yoshihisa Nakamura, Makoto Yokota, Shinya Ozaki, Shingo Murakami
OBJECTIVE: We previously reported a modified endoscopic medial maxillectomy (modified transnasal endoscopic medial maxillectomy through prelacrimal duct approach [MTEMMPDA]) to resect inverted papilloma (IP), for which the inferior turbinate (IT) and nasolacrimal duct (ND) can be preserved. MTEMMPDA is a safe and effective method to obtain wide, straight access to the maxillary sinus (MS). However, there are few reported cases of patients who underwent MTEMMPDA, and even fewer of patients who underwent partial osteotomy of the apertura piriformis and the anterior wall of the MS...
March 14, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28294609/biseokeaniamides-a-b-and-c-sterol-o-acyltransferase-inhibitors-from-an-okeania-sp-marine-cyanobacterium
#7
Arihiro Iwasaki, Takato Tadenuma, Shimpei Sumimoto, Taichi Ohshiro, Kaori Ozaki, Keisuke Kobayashi, Toshiaki Teruya, Hiroshi Tomoda, Kiyotake Suenaga
Biseokeaniamides A, B, and C (1-3), structurally novel sterol O-acyltransferase (SOAT) inhibitors, were isolated from an Okeania sp. marine cyanobacterium. Their structures were elucidated by spectroscopic analyses and degradation reactions. Biseokeaniamide B (2) exhibited moderate cytotoxicity against human HeLa cancer cells, and compounds 1-3 inhibited both SOAT1 and SOAT2, not only at an enzyme level but also at a cellular level. Biseokeaniamides (1-3) are the first linear lipopeptides that have been shown to exhibit SOAT-inhibitory activity...
March 15, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/28294559/the-platelet-activating-receptor-c-type-lectin-receptor-2-plays-an-essential-role-in-liver-regeneration-after-partial-hepatectomy-in-mice
#8
Hiroshi Kono, Hideki Fujii, Katsue Suzuki-Inoue, Osamu Inoue, Shinji Furuya, Kazuyoshi Hirayama, Yasuhiro Akazawa, Yuuki Nakata, Chao Sun, Nagaharu Tsukiji, Toshiaki Shirai, Yukio Ozaki
BACKGROUND AND AIM: The aim of the present study was to investigate the role of CLEC-2 in liver regeneration following partial liver resection in mice. MATERIALS AND METHODS: Irradiated chimeric mice transplanted with fetal liver cells from wild-type (WT), CLEC-2 deleted (KO), or CLEC-2 deleted specifically from platelets (flKO) mice were generated. Mice underwent 70% partial hepatectomy (PH). Immunohistochemical staining was performed to investigate the expression of the endogenous ligand for CLEC-2, podoplanin...
March 12, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28293475/nationwide-hospital-based-survey-of-idiopathic-normal-pressure-hydrocephalus-in-japan-epidemiological-and-clinical-characteristics
#9
Nagato Kuriyama, Masakazu Miyajima, Madoka Nakajima, Michiko Kurosawa, Wakaba Fukushima, Yoshiyuki Watanabe, Etsuko Ozaki, Yoshio Hirota, Akiko Tamakoshi, Etsuro Mori, Takeo Kato, Takahiko Tokuda, Akinori Urae, Hajime Arai
OBJECTIVES: There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus (iNPH) in Japan. Therefore, a nationwide epidemiologic survey of iNPH was performed to determine the number of cases and clinical characteristics by sex and diagnostic level. METHODS: The first survey examined the numbers of cases that met the diagnostic criteria of iNPH and those who underwent shunt operations in 2012. The second survey gathered patients' details to clarify their clinical background characteristics...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28287388/kerboull-type-plate-in-a-direct-anterior-approach-for-severe-bone-defects-at-primary-total-hip-arthroplasty-technical-note
#10
Mikio Matsumoto, Tomonori Baba, Hironori Ochi, Yu Ozaki, Taiji Watari, Yasuhiro Homma, Kazuo Kaneko
INTRODUCTION: For cases with extensive acetabular bone defects, we perform surgery combining the Kerboull-type (KT) plate and bone graft through direct anterior approach (DAA) in primary total hip arthroplasty (THA) requiring acetabular reconstruction as minimally invasive surgery. This paper provides the details of the surgical procedure. METHODS: The basic structure of the Kerboull-type plate is a cruciform plate. Since the hook of the Kerboull-type plate has to be applied to the tear drop, a space for it was exposed...
2017: SICOT-J
https://www.readbyqxmd.com/read/28284891/loss-of-bap1-protein-expression-in-the-first-metastatic-site-predicts-prognosis-in-patients-with-clear-cell-renal-cell-carcinoma
#11
Yuji Miura, Naoko Inoshita, Masaomi Ikeda, Yu Miyama, Ryosuke Oki, Suguru Oka, Chihiro Kondoh, Yukinori Ozaki, Yuko Tanabe, Kazuhiro Kurosawa, Shinji Urakami, Tadasu Kohno, Toshikazu Okaneya, Toshimi Takano
OBJECTIVES: To investigate the intratumoral heterogeneity of BAP1 and PBRM1 expression at the primary site and metastatic sites and to evaluate whether BAP1 and PBRM1 expression in metastatic sites of clear cell renal cell carcinoma (ccRCC) has prognostic value. METHODS AND MATERIALS: We collected paired samples from the primary site and the first metastatic site in 41 patients with ccRCC. Immunohistochemistry analyses were performed for the expression of BAP1 and PBRM1 proteins...
March 8, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28283028/a-pregnant-woman-with-a-surgical-site-infection-after-mesh-repair-of-an-abdominal-wall-incisional-hernia-a-case-report
#12
Kana Ozaki, Kenji Tanimura, Yasuhiko Ebina, Kiyonori Kanemitsu, Hideto Yamada
BACKGROUND: Surgical meshes are widely used in incisional hernia repair. However, there are no reports of pregnancies complicated by infection of surgical meshes used for hernia repair. This is the first case report of a pregnant woman who experienced surgical site infection associated with surgical mesh used for repair of an abdominal wall incisional hernia. CASE PRESENTATION: We report a case of a 41-year-old pregnant Japanese woman with surgical site infection after mesh repair of an abdominal wall incisional hernia...
March 11, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28282759/japanese-female-kendo-practitioners-are-associated-with-high-radial-bone-mineral-density
#13
Daisuke Matsui, Isao Watanabe, Teruhide Koyama, Etsuko Ozaki, Nagato Kuriyama, Shigeto Mizuno, Yoshiyuki Watanabe
Osteopenia is a condition in which bone mineral density (BMD) is lower than normal. Exercise increases BMD in both the young and adults. This study aimed to compare the radial apparent BMD (aBMD) in Japanese females who are Kendo practitioners (KPs) and those with no regular exercise habits (no-REH). The analysis participants consisted of 45 KPs (mean age: 49.4 years old) and 110 no-REH (mean age: 48.8 years old). Radial aBMD was measured using an ultrasonic bone densitometry system. Radial aBMD in KPs was 196...
September 26, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28279981/in-utero-exposure-to-maternal-hyperglycemia-increases-childhood-cardiometabolic-risk-in-offspring
#14
Wing Hung Tam, Ronald Ching Wan Ma, Risa Ozaki, Albert Martin Li, Michael Ho Ming Chan, Lai Yuk Yuen, Terence Tzu Hsi Lao, Xilin Yang, Chung Shun Ho, Gregory Emanuele Tutino, Juliana Chung Ngor Chan
OBJECTIVE: The objective of this study was to evaluate the effect of maternal hyperglycemia during pregnancy on cardiometabolic risk in offspring during early childhood. RESEARCH DESIGN AND METHODS: A total of 970 mothers who had joined the Hyperglycemia and Adverse Pregnancy Outcome study were reevaluated, together with their child born during the study period, 7 years after delivery. RESULTS: Offspring born to mothers diagnosed with gestational diabetes mellitus (GDM), as defined by World Health Organization 2013, had higher rates of abnormal glucose tolerance (4...
March 9, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28272511/non-destructive-monitoring-of-mouse-embryo-development-and-its-qualitative-evaluation-at-the-molecular-level-using-raman-spectroscopy
#15
Mika Ishigaki, Kosuke Hashimoto, Hidetoshi Sato, Yukihiro Ozaki
Current research focuses on embryonic development and quality not only by considering fundamental biology, but also by aiming to improve assisted reproduction technologies, such as in vitro fertilization. In this study, we explored the development of mouse embryo and its quality based on molecular information, obtained nondestructively using Raman spectroscopy. The detailed analysis of Raman spectra measured in situ during embryonic development revealed a temporary increase in protein content after fertilization...
March 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28270251/decontamination-work-and-the-long-term-increase-in-hospital-visits-for-hymenoptera-stings-following-the-fukushima-nuclear-disaster
#16
Akihiko Ozaki, Takeru Yokota, Shuhei Nomura, Masaharu Tsubokura, Claire Leppold, Tetsuya Tanimoto, Toru Miura, Kana Yamamoto, Toyoaki Sawano, Manabu Tsukada, Masahiro Kami, Yukio Kanazawa, Hiromichi Ohira
OBJECTIVE: Animals, including arthropods, are one health threat that can be affected by disasters. This institution-based study aimed to assess trends in Hymenoptera stings following the 2011 Fukushima nuclear disaster. METHODS: We reviewed the medical records of patients with hymenopteran stings who visited Minamisoma Municipal General Hospital, located 23 km from Fukushima Daiichi Nuclear Power Plant, from March 2005 to March 2016. Patient and sting characteristics of post-disaster patients were examined, and the annual incidence of hospital visits for hymenopteran stings was compared with the pre-disaster baseline, calculating an incidence rate ratio (IRR) for each year...
March 8, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28268467/characterizing-muscular-activities-using-non-negative-matrix-factorization-from-emg-channels-for-driver-swings-in-golf
#17
Yasunori Ozaki, Ryosuke Aoki, Toshitaka Kimura, Youichi Takashima, Tomohiro Yamada
The goal of this study is to propose a data driven approach method to characterize muscular activities of complex actions in sports such as golf from a lot of EMG channels. Two problems occur in a many channel measurement. The first problem is that it takes a lot of time to check the many channel data because of combinatorial explosion. The second problem is that it is difficult to understand muscle activities related with complex actions. To solve these problems, we propose an analysis method of multi EMG channels using Non-negative Matrix Factorization and adopt the method to driver swings in golf...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28267224/prognostic-value-of-programmed-death-ligand-1-expression-in-patients-with-stage-iii-colorectal-cancer
#18
Shigehiro Koganemaru, Naoko Inoshita, Yuji Miura, Yu Miyama, Yudai Fukui, Yukinori Ozaki, Kenji Tomizawa, Yutaka Hanaoka, Shigeo Toda, Koichi Suyama, Yuko Tanabe, Jin Moriyama, Takeshi Fujii, Shuichiro Matoba, Hiroya Kuroyanagi, Toshimi Takano
The Programmed death-1/ Programmed death-ligand 1 (PD-L1) pathway is a negative feedback pathway that suppresses the activity of T cells. Previous studies reported that high PD-L1 expression on tumor cells (TCs) was associated with poor survival in patients with colorectal cancer; however, the prognostic evaluation of these studies was limited because they included patients at various disease stages. The purpose of this study was to evaluate the relationship between PD-L1 status in the immune microenvironment and the clinicopathological features of stage III colorectal cancer...
March 7, 2017: Cancer Science
https://www.readbyqxmd.com/read/28265760/a-novel-suture-technique-using-the-fast-fix-combined-with-ultrabraid-for-pullout-repair-of-the-medial-meniscus-posterior-root-tear
#19
Masataka Fujii, Takayuki Furumatsu, Yuya Kodama, Shinichi Miyazawa, Tomohito Hino, Yusuke Kamatsuki, Kazuki Yamada, Toshifumi Ozaki
Medial meniscus posterior root has an important role in the maintenance of knee articular cartilage. Although pullout repair of the medial meniscus posterior root tear has become a gold standard, it has several difficulties for suturing. We have developed a modified Mason-Allen suture technique using the FasT-Fix all-inside suture device combined with Ultrabraid. The present suture technique allows a strong grasping of the medial meniscus posterior horn for arthroscopic pullout repair.
March 6, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28264114/perspectives-on-care-for-the-elderly-in-china
#20
Fei Wu, Tomohiro Morita, Akihiko Ozaki
No abstract text is available yet for this article.
March 1, 2017: JAMA Internal Medicine
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