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https://www.readbyqxmd.com/read/28805870/an-enhanced-degree-of-charge-transfer-in-dye-sensitized-solar-cells-with-a-zno-tio2-n3-ag-structure-as-revealed-by-surface-enhanced-raman-scattering
#1
Xiaolei Wang, Peng Li, Xiao Xia Han, Yasutaka Kitahama, Bing Zhao, Yukihiro Ozaki
A number of recent studies have focused on improving the performance of dye-sensitized solar cells (DSSCs). Cells with a ZnO-TiO2/N3/Ag structure have attracted particular attention because of their excellent power conversion efficiencies. Using a dendritic crystal ZnO-TiO2 composite semiconductor and Ag in conjunction leads to different charge-transfer (CT) processes, and this is the main theoretical basis for the improvement of DSSC performances. Thus, in the present study, TiO2/N3, ZnO/N3, ZnO-TiO2/N3, TiO2/N3/Ag, ZnO/N3/Ag, and ZnO-TiO2/N3/Ag assemblies have been fabricated and their CT processes have been monitored by using surface-enhanced Raman scattering (SERS) spectra, with particular focus on the differences caused by the synergistic effect of the ZnO-TiO2 component...
August 14, 2017: Nanoscale
https://www.readbyqxmd.com/read/28803882/changes-in-coumarin-kinetics-and-subcellular-localization-of-cyp2e1-contribute-to-bile-duct-damage-and-reduce-hepatocellular-damage-after-repeated-administration-of-coumarin-in-rats
#2
Yasuhiro Tanaka, Wataru Fujii, Hisako Hori, Yoshinori Kitagawa, Kiyokazu Ozaki
Coumarin exhibits different hepatotoxicity in rats depending on the administration frequency. To investigate the underlying mechanisms for the differences, we administered coumarin to rats as a single dose or repeatedly for 4 weeks. We found large increases in blood levels of liver enzymes and noticeable centrilobular hepatic necrosis after a single dose of coumarin. After repeated administration, enzyme levels mildly increased, while those of γ-GTP and total bilirubin significantly increased, suggesting bile duct damage...
August 10, 2017: Toxicology Letters
https://www.readbyqxmd.com/read/28793985/long-term-hyperglycemia-naturally-induces-dental-caries-but-not-periodontal-disease-in-type-1-and-type-2-diabetic-rodents
#3
Yutaka Nakahara, Kiyokazu Ozaki, Tetsuro Matsuura
Periodontal disease (PD) in diabetic patients is described as the 6th complication of diabetes. We have previously shown that diabetes increases dental caries, and carious inflammation might have a strong effect on the adjacent periodontal tissue in diabetic rodent models. However, the possibility that hyperglycemia may induce PD in diabetic animals could not be completely eliminated. The goal of this study was to confirm the presence of PD in diabetic animal models by preventing carious inflammation with fluoride administration...
August 9, 2017: Diabetes
https://www.readbyqxmd.com/read/28791864/melting-of-oxygen-vacancy-order-at-oxide-heterostructure-interface
#4
Kei Hirai, Ryotaro Aso, Yusuke Ozaki, Daisuke Kan, Mitsutaka Haruta, Noriya Ichikawa, Hiroki Kurata, Yuichi Shimakawa
Modifications of oxygen coordination environments in heterostructures consisting of dissimilar oxides often emerge and lead to unusual properties of the constituent materials. While lots of attention has been paid on slight modifications of rigid oxygen octahedra of perovskite-based heterointerfaces, revealing the modification behaviors of the oxygen coordination environments in the heterostructures containing oxides with oxygen vacancies has been challenging. Here we show that a significant modification of oxygen coordination environments -melting of oxygen vacancy order- is induced at the heterointerface between SrFeO2...
August 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28790306/quantitative-diagnostic-imaging-of-cancer-tissues-by-using-phosphor-integrated-dots-with-ultra-high-brightness
#5
Kohsuke Gonda, Mika Watanabe, Hiroshi Tada, Minoru Miyashita, Yayoi Takahashi-Aoyama, Takashi Kamei, Takanori Ishida, Shin Usami, Hisashi Hirakawa, Yoichiro Kakugawa, Yohei Hamanaka, Ryuichi Yoshida, Akihiko Furuta, Hisatake Okada, Hideki Goda, Hiroshi Negishi, Kensaku Takanashi, Masaru Takahashi, Yuichi Ozaki, Yuka Yoshihara, Yasushi Nakano, Noriaki Ohuchi
The quantitative sensitivity and dynamic range of conventional immunohistochemistry (IHC) with 3,3'-diaminobenzidine (IHC-DAB) used in pathological diagnosis in hospitals are poor, because enzyme activity can affect the IHC-DAB chromogenic reaction. Although fluorescent IHC can effectively increase the quantitative sensitivity of conventional IHC, tissue autofluorescence interferes with the sensitivity. Here, we created new fluorescent nanoparticles called phosphor-integrated dots (PIDs). PIDs have 100-fold greater brightness and a more than 300-fold greater dynamic range than those of commercially available fluorescent nanoparticles, quantum dots, whose fluorescence intensity is comparable to tissue autofluorescence...
August 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28790215/-a-case-of-ruptured-distal-anterior-choroidal-artery-aneurysm-associated-with-a-twig-like-middle-cerebral-artery-treated-with-single-stage-aneurysm-clipping-and-sta-mca-double-anastomoses-in-the-acute-phase
#6
Toshimoto Seno, Kanehisa Kohno, Hideo Tanaka, Shinji Iwata, Shinya Fukumoto, Haruhisa Ichikawa, Noriyuki Fumoto, Akihiro Inoue, Saya Ozaki, Yawara Nakamura, Shohei Kohno, Shiro Ohue
We report the case of a patient who has progressed well over 5 years following single-stage aneurysm clipping and superficial temporal artery-middle cerebral artery(STA-MCA)double anastomoses in the acute phase, for a ruptured distal anterior choroidal artery(AChA)aneurysm accompanied by a twig-like MCA. The patient was a 49-year-old female who developed a sudden severe headache and disturbance of consciousness due to subarachnoid hemorrhage and intraventricular hemorrhage(IVH). Cerebral angiography showed a right twig-like MCA associated with an abnormal vascular network and a ruptured aneurysm in the distal AChA...
August 2017: No Shinkei Geka. Neurological Surgery
https://www.readbyqxmd.com/read/28781793/activation-of-the-arachidonic-acid-metabolic-pathway-and-induction-of-sleep-disturbance-by-sacral-osteoblastoma-a-case-report
#7
Mitsunori Ozaki, Kazuya Nishioka, Akihiko Kimura, Toshikazu Kondo, Naoyuki Nakao
Osteoblastomas are benign bone tumors that produce prostaglandin and promote inflammation. The aim of the present study was to describe the clinical and radiological characteristics of a pediatric osteoblastoma case over an 8-month postoperative follow-up. The case involved an 11-year-old female patient with normal somatic development, presenting with a chief complaint of sleep disturbance. The patient had no spontaneous pain or other readily evident possible causes. Magnetic resonance imaging (MRI) revealed a neoplastic lesion in the sacrum, with peritumoral edema...
August 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28770700/detection-of-necroptosis-in-ligand-mediated-and-hypoxia-induced-injury-of-hepatocytes-using-a-novel-optic-probe-detecting-receptor-interacting-protein-rip-1-rip3-binding
#8
Sanae Haga, Akira Kanno, Takeaki Ozawa, Naoki Morita, Mami Asano, Michitaka Ozaki
Liver injury is often observed in various pathological conditions including posthepatectomy state and cancer chemotherapy. It occurs mainly as a consequence of the combined necrotic and apoptotic types of cell death. In order to study liver/hepatocyte injury by necrotic type of cell death, we studied signal-regulated necrosis (necroptosis) by newly developing an optic probe detecting receptor-interacting protein (RIP)1/RIP3 binding, an essential process for necroptosis induction. In the mouse hepatocyte cell line, TIB-73 cells, TNF-a/cycloheximide (T/C) induced RIP1/3 binding only when caspase activity was suppressed by z-VAD-fmk (zVAD), a caspase-specific inhibitor...
July 21, 2017: Oncology Research
https://www.readbyqxmd.com/read/28770281/determination-of-the-extent-of-trace-metals-pollution-in-soils-sediments-and-human-hair-at-e-waste-recycling-site-in-ghana
#9
Takashi Tokumaru, Hirokazu Ozaki, Siaw Onwona-Agyeman, John Ofosu-Anim, Izumi Watanabe
The concentrations of trace elements (Mg, Al, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ga, As, Se, Rb, Sr, Y, Mo, Cd, In, Sn, Sb, Cs, Ba, Tl, Pb, and Bi) in soils, sediment, human hair, and foodstuff collected around the electronic waste (e-waste) recycling sites in Accra, Ghana were detected using inductively coupled plasma-mass spectrometry (ICP-MS). High levels of Cu, Zn, Mo, Cd, In, Sn, Sb, and Pb were observed in soils collected from the e-waste recycling sites. Four sequential extraction procedures were used to evaluate the mobility and bioavailability of metals (Cu, Zn, Cd, Sb, and Pb)...
August 2, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28766253/imaging-assessment-of-bioresorbable-vascular-scaffolds
#10
REVIEW
Yohei Sotomi, Pannipa Suwannasom, Erhan Tenekecioglu, Carlos Collet, Shimpei Nakatani, Takayuki Okamura, Takashi Muramatsu, Yuki Ishibashi, Hiroki Tateishi, Yosuke Miyazaki, Taku Asano, Yuki Katagiri, Constantin von Zur Muehlen, Kengo Tanabe, Ken Kozuma, Yukio Ozaki, Patrick W Serruys, Yoshinobu Onuma
Vascular reparative therapy has become a reality with bioresorbable scaffolds (BRSs). To assess acute and long-term performance of the device, multimodality imaging would be essential. Radiopacity of metal hinders the imaging assessment, whereas radiolucent polymeric scaffolds allow for a precise imaging assessment with either invasive or non-invasive modality at baseline and at follow-up, which is one of the advantages of polymeric BRSs. Recent large trials evaluating clinical results of the first-generation BRS technology raised concerns about the safety and efficacy of these devices, namely, scaffold thrombosis...
August 1, 2017: Cardiovascular Intervention and Therapeutics
https://www.readbyqxmd.com/read/28763717/regional-decrease-in-gray-matter-volume-is-related-to-body-dissatisfaction-in-anorexia-nervosa
#11
Kunihiro Kohmura, Yasunori Adachi, Satoshi Tanaka, Hiroto Katayama, Miho Imaeda, Naoko Kawano, Kazuo Nishioka, Masahiko Ando, Tetsuya Iidaka, Norio Ozaki
Anorexia nervosa (AN) is a psychiatric disorder, in which the prognosis for some patients is poor. The etiology and effective treatments for AN have not been established. We examined morphometric changes in the brain of AN and clarified how the changes were associated with symptoms and pathophysiology. We enrolled 52 participants: 7 with the restrictive type of AN, 13 with the binge-eating/purging type, 3 with eating disorder not otherwise specified, and 29 healthy controls. Participants underwent T1-weighted MRI...
July 25, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28763059/rare-genetic-variants-in-cx3cr1-and-their-contribution-to-the-increased-risk-of-schizophrenia-and-autism-spectrum-disorders
#12
K Ishizuka, Y Fujita, T Kawabata, H Kimura, Y Iwayama, T Inada, Y Okahisa, J Egawa, M Usami, I Kushima, Y Uno, T Okada, M Ikeda, B Aleksic, D Mori, To Someya, T Yoshikawa, N Iwata, H Nakamura, T Yamashita, N Ozaki
CX3CR1, a G protein-coupled receptor solely expressed by microglia in the brain, has been repeatedly reported to be associated with neurodevelopmental disorders including schizophrenia (SCZ) and autism spectrum disorders (ASD) in transcriptomic and animal studies but not in genetic studies. To address the impacts of variants in CX3CR1 on neurodevelopmental disorders, we conducted coding exon-targeted resequencing of CX3CR1 in 370 Japanese SCZ and 192 ASD patients using next-generation sequencing technology, followed by a genetic association study in a sample comprising 7054 unrelated individuals (2653 SCZ, 574 ASD and 3827 controls)...
August 1, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28762400/interpretation-of-the-%C3%A3-%C3%A2-x-combining-tilde-transition-of-hydrated-protons-in-aqueous-solutions-observed-in-the-far-uv-region-with-quantum-chemical-calculations
#13
Takeyoshi Goto, Krzysztof B Beć, Yukihiro Ozaki
Far-ultraviolet spectra (wavelength: 140-200 nm) of group I, II, and XIII cation nitrate electrolyte aqueous solutions show that the first electronic transition (Ã ← X[combining tilde]) energies of water hydrating the cations are linearly dependent on the hydration energies of the cations. However, deviations from these linear relations have been observed only for electrolyte solutions of small cations, i.e., H(+), Li(+), and Be(2+) (T. Goto, A. Ikehata, Y. Morisawa, N. Higashi and Y. Ozaki, Phys. Chem. Chem...
August 1, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28760582/improved-outcomes-with-proximal-radial-cephalic-arteriovenous-fistulas-compared-with-brachial-cephalic-arteriovenous-fistulas
#14
Dean J Arnaoutakis, Elise P Deroo, Patrick McGlynn, Maxwell D Coll, Michael Belkin, Dirk M Hentschel, C Keith Ozaki
BACKGROUND: Brachial-cephalic arteriovenous fistulas (BCFs) are associated with high-flow volumes, leading to potential risks such as arm swelling, steal syndrome, pseudoaneurysm (due to a pressurized access), and cephalic arch stenosis. We hypothesized that a proximal radial-cephalic fistula (prRCF) configuration mitigates these risks because a lower flow state is created. Furthermore, we also hypothesized that despite these lower flows, patencies (primary, primary assisted, secondary) are sustained...
July 28, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28756461/adolescent-stress-leads-to-glutamatergic-disturbance-through-dopaminergic-abnormalities-in-the-prefrontal-cortex-of-genetically-vulnerable-mice
#15
Yurie Matsumoto, Minae Niwa, Akihiro Mouri, Yukihiro Noda, Takeshi Fukushima, Norio Ozaki, Toshitaka Nabeshima
BACKGROUND: Stress during the adolescent period influences postnatal maturation and behavioral patterns in adulthood. Adolescent stress-induced molecular and functional changes in neurons are the key clinical features of psychiatric disorders including schizophrenia. OBJECTIVE: In the present study, we exposed genetically vulnerable mice to isolation stress to examine the molecular changes in the glutamatergic system involving N-methyl-d-aspartate (NMDA) receptors via dopaminergic disturbance in the prefrontal cortex (PFc)...
July 29, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28753407/il-29-enhances-cxcl10-production-in-tnf-%C3%AE-stimulated-human-oral-epithelial-cells
#16
Yoshitaka Hosokawa, Ikuko Hosokawa, Satoru Shindo, Kazumi Ozaki, Takashi Matsuo
Interleukin-29 (IL-29) is a cytokine belonging to the Type III interferon family. It was recently detected in the gingival crevicular fluid of periodontitis patients. However, the role of IL-29 in the pathogenesis of periodontal disease remains unknown. The aim of this study was to examine the effects of IL-29 on C-X-C motif chemokine ligand 10 (CXCL10) production in human oral epithelial cells. We measured CXCL10 production in TR146 cells, which is a human oral epithelial cell line, using an enzyme-linked immunosorbent assay...
August 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28752178/inhibitory-effect-of-jak-inhibitor-on-mechanical-stress-induced-protease-expression-by-human-articular-chondrocytes
#17
Takahiro Machida, Keiichiro Nishida, Yoshihisa Nasu, Ryuichi Nakahara, Masatsugu Ozawa, Ryozo Harada, Masahiro Horita, Ayumu Takeshita, Daisuke Kaneda, Aki Yoshida, Toshifumi Ozaki
OBJECTIVE: To investigate whether janus kinase (JAK) inhibitor exhibits a chondro-protective effect against mechanical stress-induced expression of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) and matrix metalloproteinase (MMPs) in human chondrocytes. MATERIALS AND METHODS: Normal human articular chondrocytes were seeded onto stretch chambers and incubated with or without tofacitinib (1000 nM) for 12 h before mechanical stimulation or cytokine stimulation...
July 27, 2017: Inflammation Research: Official Journal of the European Histamine Research Society ... [et Al.]
https://www.readbyqxmd.com/read/28742402/association-of-il-10-regulating-micrornas-in-peripheral-blood-mononuclear-cells-with-the-pathogenesis-of-autoimmune-thyroid-disease
#18
Yukina Takuse, Mikio Watanabe, Naoya Inoue, Ritsuko Ozaki, Hiroshi Ohtsu, Minori Saeki, Yuka Katsumata, Yoh Hidaka, Yoshinori Iwatani
Interleukin (IL)-10 is known to suppress inflammation in autoimmune diseases. IL-10 can be regulated by miRNAs. To elucidate the involvement of miRNAs that regulate IL-10 expression with the pathogenesis of autoimmune thyroid disease (AITD), we examined the expression levels of hsa-miR-27a-3p, hsa-miR-98-5p, hsa-miR-106a-5p, and hsa-miR-223-3p in peripheral blood mononuclear cells (PBMCs) from 43 patients with Graves' disease (GD), 38 patients with Hashimoto's disease (HD), and 21 healthy volunteers. We evaluated the association between the expression levels of four miRNAs and intracellular expression of IL-10 in PBMCs from 11 healthy volunteers...
August 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28740521/new-quantitative-ultrasound-techniques-for-bone-analysis-at-the-distal-radius-in-hip-fracture-cases-differences-between-femoral-neck-and-trochanteric-fractures
#19
Motoyuki Horii, Hiroyoshi Fujiwara, Ryo Sakai, Koshiro Sawada, Yasuo Mikami, Syogo Toyama, Etsuko Ozaki, Nagato Kuriyama, Masao Kurokawa, Toshikazu Kubo
BACKGROUND: Ample evidence on etiological and pathological differences between femoral neck and trochanteric fracture cases suggests the possibility of individualized treatment. There are many issues related to areal bone mineral density and other quantitative computed tomography parameters of the proximal femur. Although osteoporosis is a systemic problem, little has been reported regarding differences in bone structural parameters, including bone mineral density, between them in regions other than the proximal femur...
January 2017: Clinical Cases in Mineral and Bone Metabolism
https://www.readbyqxmd.com/read/28734311/a-monte-carlo-simulation-of-ionic-conductivity-and-viscosity-of-highly-concentrated-electrolytes-based-on-a-pseudo-lattice-model
#20
Hiroyuki Ozaki, Kentaro Kuratani, Hikaru Sano, Tetsu Kiyobayashi
Simulating three transport phenomena-ionic conductivity, viscosity, and self-diffusion coefficient-in a common Monte-Carlo framework, we discuss their relationship to the intermolecular interactions of electrolyte solutions at high concentrations (C/mol l(-1) ∼ 1). The simulation is predicated on a pseudolattice model of the solution. The ions and solvents (collectively termed "molecules") are considered dimensionless points occupying the lattice sites. The molecular transport is realized by a repetition of swapping two adjacent molecules by the stochastic Gibbs sampling process based on simple intermolecular interactions...
July 21, 2017: Journal of Chemical Physics
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