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HTA and Chronic kidney failure

D Si Ahmed-Bouali, F Bouali, F Haddoum, K Kalem, F Otmani, M Arrada
PURPOSE: In systemic sclerosis, hypertension is feared because it is often heralding severe renal impairment. The objective of our study was to identify the frequency of arterial hypertension and clarify its etiologies in this condition. PATIENTS/METHODS: Our study was prospective. From January 2008 to May 2012, we have included all patients over the age of 16 years which featured a systemic scleroderma meeting the criteria for classification of Leroy and Medsger modified...
June 2015: Annales de Cardiologie et D'angéiologie
Andy R Weale
BACKGROUND: Current systems in place in healthcare are designed to detect harm after it has happened (e.g critical incident reports) and make recommendations based on an assessment of that event. Safer Clinical Systems, a Health Foundation funded project, is designed to proactively search for risk within systems, rather than being reactive to harm. OBJECTIVES: The aim of the Safer Clinical Systems project in Renal Care was to reduce the risks associated with shared care for patients who are undergoing surgery but are looked after peri-operatively by nephrology teams on nephrology wards...
September 2013: Journal of Renal Care
Giorgio Liguori, Patrizia Belfiore, Bruno Cianciaruso, Massimo Cirillo, Simona Creazzola, Anna D'Ausilio, Natale Gaspare De Santo, Gaetana La Bella, Antonino Parlato, Alessandro Scaletti, Bruno Zamparelli
A low-protein diet is well known to slow the progression of chronic renal failure, delay initiation of dialysis, while achieving significant economic benefits. In the context of a Health Technology Assessment (HTA), a budget impact analysis model was implemented to evaluate the economic advantage of offering of low-protein diet to nephropathic patients in Campania (Italy). The implemented model takes into account only the direct costs to the national healthcare system. In particular, costs related to supplying low-protein foods are compared to dialysis costs avoided, in a scenario that evaluates different indices of Numbers Needed to Treat and compliance to treatment...
November 2012: Igiene e Sanità Pubblica
E Frigola-Capell, J Comin-Colet, J Davins-Miralles, I Gich-Saladich, M Wensing, J M Verdú-Rotellar
OBJECTIVES: Little is known on predictors of hospitalisation in ambulatory patients with chronic heart failure, and known predictors may not apply to Mediterranean countries. Our aim was to document longitudinal trends in hospitalisations and identify patient-related predictors of hospital admission, re-admission and length of stay in the targeted population. METHODS: Population-based retrospective cohort study in Catalonia (North-East Spain), including 7196 ambulatory patients (58...
January 2013: Revista Clínica Espanõla
K C Ackoundou-N'Guessan, D A Lagou, M W Tia, D A Gnionsahe, M C Guei
Chronic renal failure (CRF) represents the major cause of mortality in the nephrology unit in Ivory Coast because the means for appropriate management are lacking. The present study was performed to investigate the risk factors for CRF so that strategies for prevention could be elaborated. A case-control study was performed prospectively at the Yopougon Teaching Hospital in Abidjan from January 2006 to December 2006. Factors known to cause CRF were investigated in patients and controls. Their prevalence rates were compared with the general population...
January 2011: Saudi Journal of Kidney Diseases and Transplantation
I Juan, M J Puchades, M A Solís, B Pascual, I Torregrosa, C Ramos, M González, A Miguel
Data recorded from external visit in hospitals, reflects high number of nephrectomized patients. Most of these patients were remitted after any surgery or deteriorizated renal function or any other associated pathology. Several studies of nephrectomized patients are reported in literature concerning both healthy patients and comorbidity factors, and renal function and its evolution are evaluated. However, obtained results present a wide variability, which needs to be assessed. In this study we present a retrospective observational study of 92 one-kidney surgical patients, visited in Nephrology surgery of University Clinic Hospital...
2010: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Jeannete Puñal, Leonor Varela Lema, Domingo Sanhez-Guisande, Alberto Ruano-Ravina
BACKGROUND: End-stage renal disease is a troublesome health problem worldwide. The most usual renal replacement therapy is conventional haemodialysis (CHD), performed three times a week, 3.5-4 h per session. It has been proposed that this schedule is unphysiologic and that daily haemodialysis would be a more appropriate schedule. One of the variants of daily haemodialysis is the so-called short daily haemodialysis (SDHD), performed five to seven times per week, 1.5-3 h per session. The objective of this paper is to compare, through a systematic review, the clinical effectiveness and safety of SDHD versus CHD...
August 2008: Nephrology, Dialysis, Transplantation
V A Ukoh
BACKGROUND: There is a suggestion of an identifiable impact of hypertension on all cause mortality in rural Africa. There is however paucity of hard data on the impact of morbidity or modality from this disease. OBJECTIVE: To determine the contribution of hypertension (HT) to adult morbidity and mortality at the University of Benin Teaching Hospital (UBTH) in Benin City, Nigeria. DESIGN: Retrospective study. SETTING: University of Benin Teaching Hospital...
July 2007: East African Medical Journal
L Varela-Lema, A Ruano-Ravina
There are currently many hemodialysis modalities that are believed to be superior to conventional hemodialysis. In order to compare the effectiveness and security of the different hemodialysis techniques a systematic review was carried out. Faced with the fact that the scales available mainly focus on study design and tend to ignore external validity, a quality scale was specifically developed to assess the quality of the studies included in the review. The objective of this article is to introduce the quality assessment scale developed and present the results of its usability and applicability...
2006: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Josep Redón, Luis Cea-Calvo, José V Lozano, Cristina Fernández-Pérez, Jorge Navarro, Alvaro Bonet, Jorge González-Esteban
BACKGROUND AND OBJECTIVES: Epidemiological data on the incidence and prevalence of cardiovascular disease in chronic renal failure are scant The objective of the present study is to assess the relationship between renal function, measured by the estimated glomerular filtration rate, and the presence of early or established cardiovascular disease, in a population of hypertensives from primary care. PATIENTS AND METHODS: Cross-sectional, multicentre study carried out in primary care centres all over Spain...
April 2006: Journal of Hypertension
J Almirall, M Vaqueiro, E Antón, M L Baré, V González, E Jaimez, C Gimeno et al.
BACKGROUND: Chronic kidney disease is a major public health problem in developed countries. The incidence of patients on dialysis is increasing progressively in the last years. The ageing population and increasing incidence of diabetes and hypertension are the main causes. Moreover, the level of kidney function is now recognised as a major risk factor for cardiovascular disease, even in mild cases. There is a great unaware about the prevalence of mild to moderate chronic kidney disease in the general population...
2005: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
A Covic, D J A Goldsmith, P Gusbeth-Tatomir, I Buhaescu, M Covic
BACKGROUND: Patients with end-stage renal disease on dialysis have among the highest cardiovascular event rates documented. Abnormal nitric oxide (NO)-dependent endothelial reactivity and increased arterial stiffness are commonly described in hemodialysis (HD) patients. Measures of aortic stiffness--aortic pulse wave velocity (PWV) and augmentation index (AGI)--have been shown to be powerful predictors of survival on hemodialysis. It is not known how these parameters interfere with successful renal transplantation...
December 15, 2003: Transplantation
Adrian Covic, Mirela Diaconita, Paul Gusbeth-Tatomir, Maria Covic, Adrian Botezan, Gabriel Ungureanu, David J Goldsmith
BACKGROUND: HD has been reported to determine an increase in QTc interval and QTc dispersion (QT(max)-QT(min))-risk factors that predispose to severe ventricular arrhythmias and sudden death. However, most studies have included end-stage renal disease (ESRD) patients with significant heart pathology. We therefore aimed to study the impact of a single HD session in subjects without manifest cardiac disease. METHODS: Sixty-eight stable, non-diabetic HD patients (47...
December 2002: Nephrology, Dialysis, Transplantation
A Covic
Secondary hypertension in CRF is characterized by particular features; hemodynamics--abnormal high vascular peripheral resistance relative to the cardiac output level; circadian variability--absence of nocturnal physiological BP decline. Hypertension is the main risk factor for renal disease progression, irrespective of the underlying etiology, and is one of the major determinants of the impressive cardiovascular morbidity and mortality seen in uraemic patients (> 50% cases). The atherosclerotic risk and severe retinopathy are more important in CRF hypertension compared to other causes (including essential HTA) at similar BP levels...
July 1997: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
J P Rey, A Modesto, C Orfila, P Cozette, P Donnadieu, I Lauze, B Héran, J L Bertrand, J Camo, C Négre
We described a patient with a POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal grammapathy and Skin changes) who was found to have renal involvement with peculiar renal pathological findings. Hitherto, 17 other cases, most of them from Japan, of POEMS syndrome with renal involvement, have been published. Clinical features are variable: acute renal failure with anasarca or moderate chronic renal insufficiency with mild proteinuria. This latter presentation often passes unnoticed. There is no severe HTA, no microangiopathic hemolytic anemia...
1994: Néphrologie
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