keyword
https://read.qxmd.com/read/38534030/fep-based-nanotheranostic-platform-for-enhanced-phototherapy-ferroptosis-chemodynamic-therapy
#21
JOURNAL ARTICLE
Na An, Shuanglong Tang, Yuwei Wang, Jing Luan, Ying Shi, Minghui Gao, Chongshen Guo
Ferroptosis is an iron-dependent and lipid peroxides (LPO)-overloaded programmed damage cell death, induced by glutathione (GSH) depletion and glutathione peroxide 4 (GPX4) inactivation. However, the inadequacy of endogenous iron and reactive oxygen species (ROS) restricts the efficacy of ferroptosis. To overcome this obstacle, a near-infrared photo-responsive FeP@PEG NPs is fabricated. Exogenous iron pool can enhance the effect of ferroptosis via the depletion of GSH and further regulate GPX4 inactivation...
March 27, 2024: Small
https://read.qxmd.com/read/38533914/recycled-bone-grafts-treated-with-extracorporeal-irradiation-or-liquid-nitrogen-freezing-after-malignant-tumor-resection
#22
JOURNAL ARTICLE
Yuta Takeuchi, Akio Sakamoto, Takashi Noguchi, Junya Toguchida, Shuichi Matsuda
INTRODUCTION: Recycled bone autografts prepared using extracorporeal irradiation (ECIR) or liquid nitrogen freezing (LNF) methods have been used for the reconstruction of skeletal elements after wide resection of sarcomas involving bone tissues. Few reports include long-term follow-up data for histological analyses of recycled autografts, particularly in the case of ECIR autografts. MATERIALS: A total of 34 malignant bone and soft tissue tumors were resected and reconstructed using 11 ECIR- and 23 LNF-recycled autografts; the mean postoperative follow-ups were 14 and 8 years, respectively...
March 27, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38533873/-not-available
#23
JOURNAL ARTICLE
Maja Vestmø Maraldo, Birgitte Vrou Offersen
In early breast cancer, adjuvant moderately hypofractionated regimens are recommended for both whole breast, partial breast and locoregional irradiation which abbreviates the overall treatment time, as argued in this review. Gating is recommended as well as the use of a simultaneous integrated boost when indicated. A tangential field set-up is standard, however, for challenging cases volumetric modulated arc therapy techniques, or referral for proton therapy, may be considered. In the metastatic setting, stereotactic radiotherapy is a promising treatment option for oligometastatic disease...
March 18, 2024: Ugeskrift for Laeger
https://read.qxmd.com/read/38533789/laser-treated-mxene-as-an-electrochemical-agent-to-boost-properties-of-semitransparent-photoelectrode-based-on-titania-nanotubes
#24
JOURNAL ARTICLE
Dujearic-Stephane Kouao, Katarzyna Grochowska, Vitezslav Stranak, Petr Sezemsky, Justyna Gumieniak, Agnieszka Kramek, Jakub Karczewski, Emerson Coy, Jan Hanus, Ondrej Kylian, Mirosław Sawczak, Katarzyna Siuzdak
In this study, Ti3 C2 T x underwent laser treatment to reshape it, resulting in the formation of a TiO2 /Ti3 C2 T x heterojunction. The interaction with laser light induced the formation of spherical TiO2 composed of an anatase-rutile phase on the Ti3 C2 T x surface. Such a heterostructure was loaded over a titania nanotube (TNT) layer, and the surface area was enhanced through immersion in a TiCl4 solution followed by thermal treatment. Consequently, the photon-to-electron conversion efficiency exhibits a 10-fold increase as compared to bare TNT...
March 27, 2024: ACS Nano
https://read.qxmd.com/read/38532884/0-263-terahertz-irradiation-induced-genes-expression-changes-in-caenorhabditis-elegans
#25
JOURNAL ARTICLE
Sen Shang, Fei Gao, Qi Zhang, Tao Song, Wei Wang, Diwei Liu, Yubin Gong, Xiaoyun Lu
The biosafety of terahertz (THz) waves has emerged as a new area of concern with the gradual application of terahertz radiation. Even though many studies have been conducted to investigate the influence of THz radiation on living organisms, the biological effects of terahertz waves have not yet been fully revealed. In this study, Caenorhabditis elegans ( C. elegans ) was used to evaluate the biological consequences of whole-body exposure to 0.263 THz irradiation. The integration of transcriptome sequencing and behavioral tests of C...
April 19, 2024: IScience
https://read.qxmd.com/read/38532699/in-package-cold-plasma-treatment-to-extend-the-shelf-life-of-food
#26
JOURNAL ARTICLE
Ramalakshmi Alaguthevar, Jeyakumar Saranya Packialakshmi, Balakrishnan Murugesan, Jong-Whan Rhim, UmaMaheshwari Thiyagamoorthy
Conventional food preservation methods such as heat treatment, irradiation, chemical treatment, refrigeration, and coating have various disadvantages, like loss of food quality, nutrition, and cost-effectiveness. Accordingly, cold plasma is one of the new technologies for food processing and has played an important role in preventing food spoilage. Specifically, in-package cold plasma has become a modern trend to decontaminate, process, and package food simultaneously. This strategy has proven successful in processing various fresh food ingredients, including spinach, fruits, vegetables, and meat...
March 2024: Comprehensive Reviews in Food Science and Food Safety
https://read.qxmd.com/read/38532637/photocatalysis-meets-piezoelectricity-in-a-type-i-oxygen-vacancy-rich-batio-3-biobr-heterojunction-mechanism-insights-from-characterizations-to-dft-calculations
#27
JOURNAL ARTICLE
Yan Xu, Huan-Yan Xu, Lian-Wei Shan, Yue Liu, Mao-Chang Cao, Li-Guo Jin, Li-Min Dong
It is a challenging task to design a piezoelectric photocatalyst with excellent performance under mechanical agitation instead of ultrasonic irradiation. Integrating vacancy defects into a heterojunction seems to be an effective strategy for synergistically increasing its piezo-photocatalytic performance. For this goal, a two-step hydrothermal method was adopted to architect a type-I oxygen-vacancy-rich BaTiO3 /BiOBr heterojunction to surge the degradation of Rhodamine B (RhB) under the combined action of simulated sunlight irradiation and mechanical agitation...
March 26, 2024: Inorganic Chemistry
https://read.qxmd.com/read/38532599/high-sensitivity-of-host-helios-neuropilin-1-treg-to-pretransplant-conditioning-hampers-development-of-ox40-bright-integrin-%C3%AE-7-regulatory-cells-in-acute-gastrointestinal-gvhd
#28
JOURNAL ARTICLE
Nikolett Lupsa, Barbara Érsek, Csenge Böröczky, Dávid Kis, Eszter Szarka, Katalin Lumniczky, Géza Sáfrány, Zoltán S Zádori, Árpád Szöőr, Edit I Buzás, Zoltán Pós
This study sought to compare the behavior of Treg subsets displaying different coexpression patterns of Neuropilin-1 (Nrp1) and Helios, under the influence of gut stress unrelated to hematopoietic stem cell transplantation, pretransplantation conditioning, and posttransplant gastrointestinal acute graft versus host disease (GI-aGvHD). Host CD4+ /CD25hi /Foxp3+ Treg cells, identified by flow cytometry, were isolated from various tissues of mice affected by these stressors. Expression of CD25, CTLA-4, CD39, OX40, integrin-β7, LAG3, TGFβ/LAP, granzyme-A, -B, and interleukin-10 was compared in four Treg subsets displaying Helios or Nrp1 only, both or none...
March 26, 2024: European Journal of Immunology
https://read.qxmd.com/read/38532345/reductive-prodrug-and-aie-copolymer-nanoparticle-for-monitoring-and-chemotherapy
#29
JOURNAL ARTICLE
Zigui Wang, Guilin Li, Qiaohui Zhao, Guangyu Fu, Zengli Yang, Guojun Zhang
Polymeric micelle systems for drug delivery, monitor and chemotherapy have gained significant attention, and reductive polymeric micelle systems have become particularly attractive due to their controlled release behavior without additional assistance. However, there are challenges in accurately controlling drug and probe release from the nanoparticles and determining the loading content of drug and probe. To address these issues, we have developed a reduction-responsive Pt(IV) prodrug-based polymeric delivery system that can be dynamically monitored using aggregation-induced emission luminogens (AIE) based bioprobes...
March 26, 2024: BMC Cancer
https://read.qxmd.com/read/38531979/droplet-dynamics-affecting-the-shape-of-patterns-formed-spontaneously-by-transforming-uv-curable-emulsions
#30
JOURNAL ARTICLE
Yoshimi Inaba, Takayuki Yanagisawa
Forming large pitch and depth patterns spontaneously based on a bottom-up approach is a challenging task but with great industrial value. It is possible to spontaneously form an uneven (concave-convex) patterns with submillimeter-to-millimeter-scale pitches and depths by the direct pattern exposure of a UV-curable oil-in-water (O/W) emulsion liquid film. UV irradiation generates a latent pattern of a cured particle aggregation in the liquid film, and an uneven structure is spontaneously formed during the subsequent drying process...
March 26, 2024: Scientific Reports
https://read.qxmd.com/read/38531243/a-study-on-the-treatment-of-brain-tumors-with-bnct-using-several-moderators-with-different-thicknesses
#31
JOURNAL ARTICLE
Yinan Zhu, Zuokang Lin, Haiyan Yu, Xiaohan Yu
Boron neutron capture therapy (BNCT) is an effective binary radiation therapy that depends on nuclear capture reactions. In recent years, BNCT can be performed without a reactor owing to the development of accelerator-based neutron sources. A new BNCT irradiation facility is proposed, which is based on a 15 mA 2.5 MeV proton accelerator with a 100 μm thickness natural lithium target as a neutron converter. A great quantity of studies has shown that neutron beams with different spectra have unique therapeutic effects on tumors...
March 22, 2024: Applied Radiation and Isotopes
https://read.qxmd.com/read/38531198/mammary-tissue-derived-extracellular-matrix-hydrogels-reveal-the-role-of-irradiation-in-driving-a-pro-tumor-and-immunosuppressive-microenvironment
#32
JOURNAL ARTICLE
Tian Zhu, Steven M Alves, Arianna Adamo, Xiaona Wen, Kevin C Corn, Anastasia Shostak, Shereena Johnson, Nicholas D Shaub, Shannon E Martello, Benjamin C Hacker, Antonio D'Amore, Rizia Bardhan, Marjan Rafat
Radiation therapy (RT) is essential for triple negative breast cancer (TNBC) treatment. However, patients with TNBC continue to experience recurrence after RT. The role of the extracellular matrix (ECM) of irradiated breast tissue in tumor recurrence is still unknown. In this study, we evaluated the structure, molecular composition, and mechanical properties of irradiated murine mammary fat pads (MFPs) and developed ECM hydrogels from decellularized tissues (dECM) to assess the effects of RT-induced ECM changes on breast cancer cell behavior...
March 21, 2024: Biomaterials
https://read.qxmd.com/read/38530961/green-synthesis-of-metal-doped-zno-nanoparticles-using-bauhinia-racemosa-lam-extract-and-evaluation-of-their-photocatalysis-and-biomedical-applications
#33
JOURNAL ARTICLE
Anusuya Mariappan, Leelavathi Harikrishnan, Jayanthi Eswaran, Nagaveni Arumugham, Yogeswari Balasubramaniam, Santhanaraj Daniel, Rajakumar Kanthapazham
A fascinating problem in the fields of nanoscience and nanobiotechnology has recently emerged, and to tackle this, the production of metal oxide nanoparticles using plant extracts offers numerous benefits over traditional physicochemical methods. In the present investigation, ZnO nanoparticles were fabricated from Bauhinia racemosa Lam. (BR) leaves extract with various transition metal (TM) dopants (Ni, Mn, and Co). Plant leaves extract containing metal nitrate solutions were utilized as a precursor to synthesize the pristine and TM-doped ZnO nanoparticles...
March 26, 2024: ACS Applied Bio Materials
https://read.qxmd.com/read/38530837/how-does-ionizing-radiation-affect-amyloidogenesis-in-plants
#34
JOURNAL ARTICLE
Maryna Kryvokhyzha, Sergii Litvinov, Maksym Danchenko, Lidiia Khudolieieva, Nataliia Kutsokon, Peter Baráth, Namik Rashydov
PURPOSE: Ionizing radiation is a harsh environmental factor that could induce plant senescence. We hypothesized that radiation-related senescence remodels proteome, particularly by triggering the accumulation of prion-like proteins in plant tissues. The object of this study, pea ( Pisum sativum L.), is an agriculturally important legume. Research on the functional importance of amyloidogenic proteins was never performed on this species. MATERIALS AND METHODS: Pea seeds were irradiated in the dose range 5-50 Gy of X-rays...
March 26, 2024: International Journal of Radiation Biology
https://read.qxmd.com/read/38530747/radical-induced-photochromic-silver-i-metal-organic-frameworks-alternative-topology-dynamic-photoluminescence-and-efficient-photothermal-conversion-modulated-by-anionic-guests
#35
JOURNAL ARTICLE
Pei-Yu Liao, Jia-Xin Li, Jia-Chuan Liu, Qi Xiong, Ze-Yu Ruan, Tao Li, Wei Deng, Shang-Da Jiang, Jian-Hua Jia, Ming-Liang Tong
Photogenerated radicals are an indispensable member of the state-of-the-art photochromic material family, as they can effectively modulate the photoluminescence and photothermal conversion performance of radical-induced photochromic complexes. Herein, two novel radical-induced photochromic metal‒organic frameworks (MOFs), [Ag(TEPE)](AC)⋅7/4H2O⋅5/4EtOH (1) and [Ag(TEPE)](NC)⋅3H2O⋅EtOH (2), are reported. Distinctly different topological networks can be obtained by judiciously introducing alternative π-conjugated anionic guests, including a new topological structure (named as sfm) first reported in this work, describing as 4,4,4,4-c net...
March 26, 2024: Angewandte Chemie
https://read.qxmd.com/read/38530659/tuning-of-surface-oxygen-vacancies-for-enhancing-photocatalytic-performance-under-visible-light-irradiation-in-sb-2-wo-6-nanostructures
#36
JOURNAL ARTICLE
Manisha Sharma, Rahul Singh, Anitya Sharma, Venkata Krishnan
Tuning of vacancies in photocatalytic materials has emerged as a versatile strategy to enhance visible light absorption and photocatalytic activity. In this study, surface oxygen vacancies (defects) were incorporated on antimony tungstate to boost its photocatalytic activity, which was examined by studying the degradation of model pollutants under visible light irradiation. Specifically, a two-to-three-fold increase in photocatalytic activity was observed for oxygen vacancy-rich antimony tungstate in comparison to its pristine counterpart...
March 26, 2024: Dalton Transactions: An International Journal of Inorganic Chemistry
https://read.qxmd.com/read/38530563/exploring-the-gamma-ray-enhanced-nir-luminescence-and-cytotoxic-potential-of-lanthanide-naphthalene-dicarboxylate-based-metal-organic-frameworks
#37
JOURNAL ARTICLE
Podilapu Atchutha Rao, Harihara Padhy, Krishanu Bandyopadhyay, Adapaka Venkateswara Rao, Ravikumar Ganta, Samatha Bevara, Bheeshma Pratap Singh, Bhavani Kundrapu, Satyen Saha, RamaRao Malla, Saratchandra Babu Mukkamala
In this investigation, we explore the integration of lanthanides into Metal-Organic Frameworks (MOFs) to enable Near-Infrared (NIR) emission. Specifically, we focus on Lanthanide-Naphthalene Dicarboxylate based MOFs (Ln-MOFs), incorporating elements such as Praseodymium (Pr), Samarium (Sm), Dysprosium (Dy), and Erbium (Er). The synthesis of Ln-MOFs is achieved via the hydrothermal method. The structure, morphology, thermal stability, and luminescence properties of synthesized Ln-MOFs have been evaluated through different characterization techniques...
March 26, 2024: Journal of Fluorescence
https://read.qxmd.com/read/38530533/an-experimental-phototherapy-device-for-studying-the-effects-of-blue-light-on-patients-with-raynaud-s-phenomenon
#38
JOURNAL ARTICLE
Brett Levac, James Kerber, Emily Wagner, Jerry A Molitor, Steven S Saliterman
Raynaud's phenomenon (RP) is a condition that causes decreased blood flow to areas perfused by small blood vessels (e.g., fingers, toes). In severe cases, ulceration, gangrene, and loss of fingers may occur. Most treatments focus on inducing vasorelaxation in affected areas by the way of pharmaceuticals. Recently, animal studies have shown that vasorelaxation can be induced by non-coherent blue light (wavelength ~ 430-460 nm) through the actions of melanopsin, a photoreceptive opsin protein encoded by the OPN4 gene...
March 26, 2024: Annals of Biomedical Engineering
https://read.qxmd.com/read/38530477/visual-and-rapid-fluorescence-sensing-for-hexavalent-chromium-by-hydroxypropyl-chitosan-passivated-bismuth-based-perovskite-quantum-dots
#39
JOURNAL ARTICLE
Dangge Gao, Ailin Zhang, Bin Lyu, Jianzhong Ma
Hydroxypropyl chitosan-Cs3 Bi2 Cl9 perovskite quantum dots (HPCS-PQDs) were synthesized by a simple ligand-assisted reprecipitation method via green hydroxypropyl chitosan as the ligand and used as the specific signal of a fluorescence probe to achieve the highly sensitive detection of hexavalent chromium (Cr(VI)) and compared with chitosan-Cs3 Bi2 Cl9 QDs (CS-PQDs). HPCS-PQDs with multiple active hydroxyl passivations were found to enhance the photoluminescence quantum yield (PLQY) by 90%. After being placed in aqueous solution and irradiated with ultraviolet light for 96 h the fluorescence intensity of HPCS-PQDs remained above 60%...
March 26, 2024: Mikrochimica Acta
https://read.qxmd.com/read/38530295/photobiomodulation-for-blood-pressure-and-heart-rate-reduction-in-mastectomized-women-on-hormone-blockers-a-randomized-controlled-trial
#40
JOURNAL ARTICLE
Juliano Abreu Pacheco, Kelly Fernanda Molena, Eugenia Velludo Veiga
Objective: To assess the impact of intravascular laser irradiation of blood (ILIB) on the primitive carotid artery (PCA) hemodynamic variables, specifically blood pressure (BP) and heart rate (HR), in mastectomized patients undergoing hormone blocker treatments. Materials and methods: This study is a controlled, experimental, and randomized clinical trial. Patients were allocated into two groups: the experimental group (G1)-patients who received ILIB therapy using a 660 nm laser targeted at the PCA, and the control group (G2)-patients who did not receive ILIB therapy...
March 26, 2024: Photobiomodulation, photomedicine, and laser surgery
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