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https://www.readbyqxmd.com/read/28650092/photoactivatable-mussel-based-underwater-adhesive-proteins-by-an-expanded-genetic-code
#1
Mathias Hauf, Florian Richter, Tobias Schneider, Thomas Faidt, Berta M Martins, Tobias Baumann, Patrick Durkin, Holger Dobbek, Karin Jacobs, Andreas Möglich, Nediljko Budisa
Marine mussels exhibit potent underwater adhesion abilities under hostile conditions employing 3,4-dihydroxy-phenylalanine (Dopa)-rich mussel-adhesive proteins (MAPs). However, their recombinant production is a major biotechnological challenge. Here, we have developed a novel strategy based on genetic code expansion by engineering efficient aminoacyl-tRNA synthetases (aaRSs) for the photocaged non-canonical amino acid (ncAA) ortho-nitrobenzyl Dopa (ONB-Dopa). The engineered ONB-DopaRS enables in vivo production of MAP type 5 site-specifically equipped with multiple instances of ONB-Dopa yielding spatiotemporally controlled underwater adhesives...
June 26, 2017: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/28644776/eye-injuries-in-high-school-and-collegiate-athletes
#2
Barry P Boden, Lauren A Pierpoint, Rebecca G Boden, R Dawn Comstock, Zachary Y Kerr
BACKGROUND: Although eye injuries constitute a small percentage of high school and college sports injuries, they have the potential to be permanently debilitating. HYPOTHESIS: Eye injury rates will vary by sport, sex, and between the high school and college age groups. STUDY DESIGN: Descriptive epidemiology study. LEVEL OF EVIDENCE: Level 3. METHODS: Data from eye injury reports in high school and college athletes were obtained from the National High School Sports-Related Injury Surveillance System, High School Reporting Information Online (HS RIO) database over a 10-year span (2005-2006 through 2014-2015 school years) and the National Collegiate Athletic Association (NCAA) Injury Surveillance Program (ISP) over an 11-year span (2004-2005 through 2014-2015 school years)...
June 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28632483/cardiovascular-disease-risk-profile-of-ncaa-division-iii-intercollegiate-football-athletes-a-pilot-study
#3
Cynthia J Wright, Elizabeth L Abbey, Barbara A Brandon, Edward J Reisman, Christina M Kirkpatrick
OBJECTIVES: Concerns about the long-term cardiovascular health implications of American football participation have been investigated at the professional and Division I levels, but limited research is available at the less resourced Division III level. Therefore, the objective was to assess the cardiovascular disease risk profile of NCAA Division III intercollegiate football athletes. METHODS: Eighty-nine varsity football athletes (age=19.6±1.7 years, height=1...
June 20, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28622025/comparison-of-concussion-rates-between-ncaa-division-i-and-division-iii-men-s-and-women-s-ice-hockey-players
#4
John M Rosene, Bryan Raksnis, Brie Silva, Tyler Woefel, Paul S Visich, Thomas P Dompier, Zachary Y Kerr
BACKGROUND: Examinations related to divisional differences in the incidence of sports-related concussions (SRC) in collegiate ice hockey are limited. PURPOSE: To compare the epidemiologic patterns of concussion in National Collegiate Athletic Association (NCAA) ice hockey by sex and division. STUDY DESIGN: Descriptive epidemiology study. METHODS: A convenience sample of men's and women's ice hockey teams in Divisions I and III provided SRC data via the NCAA Injury Surveillance Program during the 2009-2010 to 2014-2015 academic years...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28614998/a-season-of-american-football-is-not-associated-with-changes-in-plasma-tau
#5
Jonathan Oliver, Margaret Jones, Anthony Anzalone, Michele Kirk, David Gable, Justin Repshas, Torie Johnson, Kina Hogland, Kaj Blennow, Henrik Zetterberg
American football athletes are routinely exposed to sub-concussive impacts over the course of the season. This study sought to examine the effect of a season of American football on plasma tau, a potential marker of axonal damage. Nineteen (n =19) National Collegiate Association (NCAA) American football athletes underwent serial blood sampling over the course of the 2014-2015 season at those times in which the number and magnitude of head impacts likely changed. Non-contact, sport-control, NCAA men's swim athletes (n=19) provided a single plasma sample for comparison...
June 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28593724/a-new-strategy-for-creating-noncanonical-amino-acid-dependent-organisms
#6
Weimin Xuan, Peter G Schultz
The use of noncanonical amino acids (ncAAs) to control an organism's viability provides a strategy for the development of conditional 'kill switches' for live vaccines or engineered human cells. Here we report an approach inspired by the posttranslational acetylation/deacetylation of lysine residues, in which a protein encoded by a gene with an in-frame nonsense codon at an essential lysine can be expressed in its native state only upon genetic incorporation of AcK, and subsequent enzymatic deacetylation in the host cell...
June 7, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28578465/perspectives-and-practices-of-athletic-trainers-and-team-physicians-implementing-the-2010-ncaa-sickle-cell-trait-screening-policy
#7
Mary Anne McDonald, Melissa S Creary, Jill Powell, Lori-Ann Daley, Charlotte Baker, Charmaine Dm Royal
Sickle cell trait (SCT) is usually benign. However, there are some conditions that may lead to SCT-related problems and put athletes with the trait at particular risk. In 2010 the National Collegiate Athletic Association (NCAA) issued a policy that required all Division I (DI) student-athletes to confirm their SCT status or sign a liability waiver to opt out of testing. Athletic trainers and team physicians play key roles in the policy implementation and we examined their perceptions and practices. Between December 2013 and March 2014 we interviewed 13 head athletic trainers and team physicians at NCAA Division I colleges and universities in North Carolina...
June 3, 2017: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/28556681/epidemiology-of-shoulder-dislocations-in-high-school-and-collegiate-athletics-in-the-united-states-2004-2005-through-2013-2014
#8
Matthew J Kraeutler, Dustin W Currie, Zachary Y Kerr, Karen G Roos, Eric C McCarty, R Dawn Comstock
BACKGROUND: Shoulder dislocations occur frequently in athletes across a variety of sports. This study provides an updated descriptive epidemiological analysis of shoulder dislocations among high school and college athletes and compares injury rates and patterns across these age groups. HYPOTHESIS: There would be no difference in injury rates/patterns between high school and college athletes. STUDY DESIGN: Descriptive epidemiology study. LEVEL OF EVIDENCE: Level 3...
May 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28535098/ball-contact-injuries-in-11-national-collegiate-athletic-association-sports-the-injury-surveillance-program-2009-2010-through-2014-2015
#9
Melissa A Fraser, Dustin R Grooms, Kevin M Guskiewicz, Zachary Y Kerr
CONTEXT:   Surveillance data regarding injuries caused by ball contact in collegiate athletes have not been well examined and are mostly limited to discussions of concussions and catastrophic injuries. OBJECTIVE:   To describe the epidemiology of ball-contact injuries in 11 National Collegiate Athletic Association (NCAA) sports during the 2009-2010 through 2014-2015 academic years. DESIGN:   Descriptive epidemiology study. SETTING:   Convenience sample of NCAA programs in 11 sports (men's football, women's field hockey, women's volleyball, men's baseball, women's softball, men's and women's basketball, men's and women's lacrosse, and men's and women's soccer) during the 2009-2010 through 2014-2015 academic years...
May 23, 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28530486/y-balance-test-performance-following-a-competitive-field-hockey-season-a-pretest-posttest-study
#10
Matthew C Hoch, Lauren A Welsch, Emily M Hartley, Cameron J Powden, Johanna M Hoch
CONTEXT: The Y-Balance Test (YBT) is a dynamic balance assessment used as a preseason musculoskeletal screen to determine injury risk. While the YBT has demonstrated excellent test-retest reliability, it is unknown if YBT performance changes following participation in a competitive athletic season. OBJECTIVE: Determine if a competitive athletic season affects YBT performance in field hockey players. DESIGN: Pretest-posttest. SETTING: Laboratory...
May 22, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28529463/nutrition-practices-and-knowledge-among-ncaa-division-iii-football-players
#11
Elizabeth Lea Abbey, Cynthia Joy Wright, Christina M Kirkpatrick
BACKGROUND: Participation in collegiate American football is physically demanding and may have long-term health implications, particularly in relation to cardiovascular and neurological health. National Collegiate Athletic Association (NCAA) Division III (DIII) football players are a relatively unstudied population, particularly in terms of their dietary habits and knowledge. The aim of the present study was to descriptively evaluate the dietary intake of DIII football players including a subset of linemen and assess the nutritional knowledge and sources of information of these athletes...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28515977/establishing-normative-change-values-in-visual-acuity-loss-during-the-dynamic-visual-acuity-test
#12
Chris Marquez, Monica Lininger, Scot Raab
BACKGROUND: Baseline visual acuity (VA) loss from static to dynamic head conditions assessed using the Dynamic Visual Acuity Testing (DVAT) have not been established in NCAA football players. DVAT assesses the Vestibulo-Ocular Reflex (VOR) which is measured in Logarithm of the Minimum Angle of Resolution (logMAR). Decreased VA beyond baseline measures may detect VOR impairment and impact treatment protocols and assist in return to play decisions post-concussion. HYPOTHESIS/PURPOSE: To establish normative VA mean scores during a static head posture as well as dynamically during the DVAT with a head speed of 150 deg/s in the pitch (vertical) and yaw (horizontal) planes rotating 20 degrees in each direction...
April 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28515972/determination-of-clinically-relevant-differences-in-frontal-plane-hop-tests-in-women-s-collegiate-basketball-and-soccer-players
#13
Kelly Hardesty, Eric J Hegedus, Kevin R Ford, Anh-Dung Nguyen, Jeffrey B Taylor
BACKGROUND: ACL injury prevention programs are less successful in female basketball players than in soccer players. Previous authors have identified anthropometric and biomechanical differences between the athletes and different sport-specific demands, including a higher frequency of frontal plane activities in basketball. Current injury risk screening and preventive training practices do not place a strong emphasis on frontal plane activities. The medial and lateral triple hop for distance tests may be beneficial for use in the basketball population...
April 2017: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/28502817/concussion
#14
REVIEW
William J Mullally
Concussion has been recognized as a clinical entity for more than 1000 years. Throughout the 20(th) century it was studied extensively in boxers(1,2,3) but did not pique the interest of the general population as it is the accepted goal of the boxer to inflict such an injury on their opponent. In 2002, however, the possibility that repetitive concussions could result in chronic brain damage and a progressive neurologic disorder was raised by a postmortem evaluation of a retired player in the most popular sports institution in the United States, the National Football League(4,5)...
May 11, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28480575/comprehensive-headache-experience-in-collegiate-student-athletes-an-initial-report-from-the-ncaa-headache-task-force
#15
Tad Seifert, Alicia Sufrinko, Robert Cowan, W Scott Black, Dave Watson, Bill Edwards, Scott Livingston, Keith Webster, David Akers, Mathew Lively, Anthony P Kontos
BACKGROUND: The prevalence of primary headache disorders in the general population provides a unique challenge in the evaluation of headache occurring in the context of sport. Despite a wealth of studies exploring the epidemiology of headache in the layperson, little is known about the prevalence and nature of headaches in collegiate student-athletes. These scenarios are challenging in the return to play context, as it is often unclear whether an athlete has an exacerbation of a primary headache disorder, new onset headache unrelated to trauma, or has suffered a concussive injury...
May 7, 2017: Headache
https://www.readbyqxmd.com/read/28473995/concussion-management-plan-compliance-a-study-of-ncaa-power-5-conference-schools
#16
Thomas A Buckley, Christine M Baugh, William P Meehan, Melissa S DiFabio
BACKGROUND: In response to concerns over concussions and repeated head impacts that occur during sports, the National Collegiate Athletic Association (NCAA) mandated that all member institutions enact a concussion management plan (CMP). Although institutional and health care provider self-reports have been investigated, compliance with NCAA protocol recommendations has not been examined. PURPOSE: To examine the CMPs from the 65 institutions within the NCAA Power 5 conferences for compliance with the NCAA 2015 concussion guidelines...
April 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28467580/how-to-avoid-negative-appendectomies-can-us-achieve-this
#17
Kinyas Kartal, Pınar Yazıcı, Taner Mehmet Ünlü, Mehmet Uludağ, Mehmet Mihmanlı
BACKGROUND: Clinical diagnosis of acute appendicitis is based primarily on symptoms and physical findings. However, diagnosis of appendicitis is not always straightforward. The aim of this study was to demonstrate the diagnostic effectiveness of ultrasonography (US) in these cases in combination with white blood cell count (WBC) and C-reactive protein (CRP) level. METHODS: Retrospective analysis of data collected on 470 consecutive patients who underwent appendectomy at the same institution between January 2014 and January 2016 was conducted...
March 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/28452636/mental-health-services-in-ncaa-division-i-athletics-a-survey-of-head-atcs
#18
Laura E Sudano, Christopher M Miles
BACKGROUND: There is a growing awareness of the importance of mental health care in National Collegiate Athletic Association (NCAA) student-athletes; however, there is a lack of literature on mental health resources in collegiate settings. Identifying current practices can set the stage to improve the delivery of care. HYPOTHESIS: There is great variability in resources and current practices and no "standard of care" exists. STUDY DESIGN: Observational, quantitative...
May 2017: Sports Health
https://www.readbyqxmd.com/read/28441037/preseason-anxiety-and-depressive-symptoms-and-prospective-injury-risk-in-collegiate-athletes
#19
Hongmei Li, Jennifer J Moreland, Corinne Peek-Asa, Jingzhen Yang
BACKGROUND: Psychological risk factors are increasingly recognized as important in sport-related injury prevention. Understanding how these psychological factors may affect the risk of injuries could help design effective prevention programs. PURPOSE: To determine the effect of reported preseason anxiety and depressive symptoms on the risk of injuries during a prospective season in a cohort of collegiate athletes. STUDY DESIGN: Cohort study; Level of evidence, 2...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28426514/comparison-of-the-hang-high-pull-and-loaded-jump-squat-for-the-development-of-vertical-jump-and-isometric-force-time-characteristics
#20
Dustin J Oranchuk, Tracey L Robinson, Zachary J Switaj, Eric J Drinkwater
Weightlifting movements have high skill demands and require expert coaching. Loaded jumps have a comparably lower skill demand, but may be similarly effective for improving explosive performance. The purpose of this study was to compare vertical jump performance, isometric force, and rate of force development (RFD) following a ten-week intervention employing the hang high-pull (hang-pull) or trap-bar jump squat (jump-squat). Eighteen NCAA Division II swimmers (8 males, 10 females) with at least one year of resistance training experience volunteered to participate...
April 15, 2017: Journal of Strength and Conditioning Research
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