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https://www.readbyqxmd.com/read/29138991/test-retest-reliability-and-interpretation-of-common-concussion-assessment-tools-findings-from-the-ncaa-dod-care-consortium
#1
Steven P Broglio, Barry P Katz, Shi Zhao, Michael McCrea, Thomas McAllister
BACKGROUND: Concussion diagnosis is typically made through clinical examination and supported by performance on clinical assessment tools. Performance on commonly implemented and emerging assessment tools is known to vary between administrations, in the absence of concussion. OBJECTIVE: To evaluate the test-retest reliability of commonly implemented and emerging concussion assessment tools across a large nationally representative sample of student-athletes. METHODS: Participants (n = 4874) from the Concussion Assessment, Research, and Education Consortium completed annual baseline assessments on two or three occasions...
November 14, 2017: Sports Medicine
https://www.readbyqxmd.com/read/29120982/total-and-segmental-body-composition-examination-in-collegiate-football-players-using-multifrequency-bia-and-dxa
#2
Christiana J Raymond, Donald R Dengel, Tyler A Bosch
The current study examined the influence of player position on the agreement between multi-frequency bioelectrical impedance analysis (MfBIA) and dual X-ray absorptiometry (DXA) when assessing total and segmental percent body fat (BF%), fat mass (FM), and fat-free mass (FFM) in NCAA Division I collegiate football athletes. Forty-four male collegiate athletes (age=19±1 yrs; height=1.9±1.0 m; weight=106.4±18.8 kg) participated. Player positions included: offensive linemen (OL; n=7), tight ends (TE; n=4), wide receivers (WR; n=9), defensive linemen (DL; n=6), defensive backs (DB; n=8), linebackers (LB; n=6), and running backs (RB; n=4)...
November 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29106828/expanding-the-scope-of-single-and-double-noncanonical-amino-acid-mutagenesis-in-mammalian-cells-using-orthogonal-polyspecific-leucyl-trna-synthetases
#3
Yunan Zheng, Raja Mukherjee, Melissa A Chin, Peter Igo, Martin J Gilgenast, Abhishek Chatterjee
Engineered aminoacyl-tRNA synthetase/tRNA pairs that enable site-specific incorporation of noncanonical amino acids (ncAAs) into proteins in living cells have emerged as powerful tools in chemical biology. The Escherichia coli-derived leucyl-tRNA synthetase (EcLeuRS)/tRNA pair is a promising candidate for ncAA mutagenesis in mammalian cells, but it has been engineered to charge only a limited set of ncAAs so far. Here we show that two highly polyspecific EcLeuRS mutants can efficiently charge a large array of useful ncAAs into proteins expressed in mammalian cells, while discriminating against the 20 canonical amino acids...
November 15, 2017: Biochemistry
https://www.readbyqxmd.com/read/29102301/y-balance-test-performance-and-bmi-are-associated-with-ankle-sprain-injury-in-collegiate-male-athletes
#4
Emily M Hartley, Matthew C Hoch, Michelle C Boling
OBJECTIVES: To determine if static balance, dynamic balance, ankle range of motion, body mass index (BMI), or history of an ankle sprain were associated with ankle sprain injuries within male and female collegiate athletes. DESIGN: Prospective cohort. METHODS: Three hundred and eighty-four male (age=19.79±1.80 years, height=178.02±10.39cm, mass=85.71±17.59kg) and one hundred and sixty seven female (age=19.80±1.52 years, height=165.61±7...
October 25, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29098599/factors-contributing-to-disparities-in-baseline-neurocognitive-performance-and-concussion-symptom-scores-between-black-and-white-collegiate-athletes
#5
Jessica Wallace, Tracey Covassin, Ryan Moran, Jamie McAllister Deitrick
BACKGROUND: National Collegiate Athletic Association (NCAA) concussion guidelines state that all NCAA athletes must have a concussion baseline test prior to commencing their competitive season. To date, little research has examined potential racial differences on baseline neurocognitive performance among NCAA athletes. The purpose of this study was to investigate differences between Black and White collegiate athletes on baseline neurocognitive performance and self-reported symptoms. METHODS: A total of 597 collegiate athletes (400 White, 197 Black) participated in this study...
November 2, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29081953/defining-the-current-scope-and-limitations-of-dual-noncanonical-amino-acid-mutagenesis-in-mammalian-cells
#6
Yunan Zheng, Partha Sarathi Addy, Raja Mukherjee, Abhishek Chatterjee
The ability to site-specifically incorporate two distinct noncanonical amino acids (ncAAs) into the proteome of a mammalian cell with high fidelity and efficiency will have many enabling applications. It would require the use of two different engineered aminoacyl-tRNA synthetase (aaRS)/tRNA pairs, each suppressing a distinct nonsense codon, and which cross-react neither with each other, nor with their counterparts from the host cell. Three different aaRS/tRNA pairs have been developed so far to expand the genetic code of mammalian cells, which can be potentially combined in three unique ways to drive site-specific incorporation of two distinct ncAAs...
October 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29067629/multifactorial-examination-of-sex-differences-in-head-injuries-and-concussions-among-collegiate-soccer-players-ncaa-iss-2004-2009
#7
Avinash Chandran, Mary J Barron, Beverly J Westerman, Loretta DiPietro
BACKGROUND: While head injuries and concussions are major concerns among soccer players, the multifactorial nature of head injury observations in this group remains relatively undefined. We aim to extend previous analyses and examine sex-differences in the incidence of head injuries, odds of head injuries within an injured sample, and severity of head injuries, among collegiate soccer players between 2004 and 2009. METHODS: Data collected within the National Collegiate Athletic Association (NCAA) Injury Surveillance System (ISS) between the years of 2004 and 2009, were analyzed in this study...
October 25, 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/29066788/periodontal-pathogenic-bacteria-aggregatibacter-actinomycetemcomitans-affect-non-alcoholic-fatty-liver-disease-by-altering-gut-microbiota-and-glucose-metabolism
#8
Rina Komazaki, Sayaka Katagiri, Hirokazu Takahashi, Shogo Maekawa, Takahiko Shiba, Yasuo Takeuchi, Yoichiro Kitajima, Anri Ohtsu, Sayuri Udagawa, Naoki Sasaki, Kazuki Watanabe, Noriko Sato, Naoyuki Miyasaka, Yuichiro Eguchi, Keizo Anzai, Yuichi Izumi
Increasing evidence indicates that periodontitis affects non-alcoholic fatty liver disease (NAFLD). We examined the relationship between periodontal bacterial infection and clinical/biochemical parameters in 52 NAFLD patients. Anti-Aggregatibacter actinomycetemcomitans (Aa) antibody titers correlated positively with visceral fat, fasting plasma insulin, and HOMA-IR; and negatively with the liver/spleen ratio. C57BL/6J mice (8-weeks-old) were given Aa or saline (control) for 6 weeks, and were fed either normal chow (NCAa, NCco) or high-fat diet (HFAa and HFco)...
October 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29065805/acute-white-matter-abnormalities-in-sports-related-concussion-a-diffusion-tensor-imaging-study-from-the-ncaa-dod-care-consortium
#9
Sourajit Mitra Mustafi, Jaroslaw Harezlak, Kevin M Koch, Andrew S Nencka, Timothy Meier, John D West, Christopher C Giza, John DiFiori, Kevin K Guskiewicz, Jason Mihalik, Stephen M LaConte, Stefan M Duma, Steven P Broglio, Andrew J Saykin, Michael McCrea, Thomas McAllister, Yu-Chien Wu
Sport-related concussion (SRC) is an important public health issue. While standardized assessment tools are useful in the clinical management of acute concussion, the underlying pathophysiology of SRC and the time course of physiological recovery after injury remain unclear. In this study, we used diffusion tensor imaging (DTI) to detect white-matter alterations in football players within 48 hours after SRC. As part of the NCAA-DoD CARE Consortium study of SRC, 30 American football players diagnosed with acute concussion, and 28 matched controls received clinical assessments and underwent advanced MRI scans...
October 25, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29064019/stability-of-mri-metrics-in-the-advanced-research-core-of-the-ncaa-dod-concussion-assessment-research-and-education-care-consortium
#10
Andrew S Nencka, Timothy B Meier, Yang Wang, L Tugan Muftuler, Yu-Chien Wu, Andrew J Saykin, Jaroslaw Harezlak, M Alison Brooks, Christopher C Giza, John Difiori, Kevin M Guskiewicz, Jason P Mihalik, Stephen M LaConte, Stefan M Duma, Steven Broglio, Thomas McAllister, Michael A McCrea, Kevin M Koch
The NCAA-DoD Concussion Assessment, Research, and Education (CARE) consortium is performing a large-scale, comprehensive study of sport related concussions in college student-athletes and military service academy cadets. The CARE "Advanced Research Core" (ARC), is focused on executing a cutting-edge investigative protocol on a subset of the overall CARE athlete population. Here, we present the details of the CARE ARC MRI acquisition and processing protocol along with preliminary analyzes of within-subject, between-site, and between-subject stability across a variety of MRI biomarkers...
October 24, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29035361/continuous-directed-evolution-of-aminoacyl-trna-synthetases
#11
David I Bryson, Chenguang Fan, Li-Tao Guo, Corwin Miller, Dieter Söll, David R Liu
Directed evolution of orthogonal aminoacyl-tRNA synthetases (AARSs) enables site-specific installation of noncanonical amino acids (ncAAs) into proteins. Traditional evolution techniques typically produce AARSs with greatly reduced activity and selectivity compared to their wild-type counterparts. We designed phage-assisted continuous evolution (PACE) selections to rapidly produce highly active and selective orthogonal AARSs through hundreds of generations of evolution. PACE of a chimeric Methanosarcina spp...
October 16, 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/29023271/dual-task-tandem-gait-and-average-walking-speed-in-healthy-collegiate-athletes
#12
David R Howell, Jessie R Oldham, William P Meehan, Melissa S DiFabio, Thomas A Buckley
OBJECTIVES: To (1) examine the association between a commonly used concussion test, tandem gait, in single/dual-task conditions with single-task and dual-task average walking speed, (2) characterize the prevalence of tandem gait false positives, and (3) develop a normative reference range of dual-task tandem gait times. DESIGN: Cross-sectional study. SETTING: Two NCAA collegiate athletic facilities. INDEPENDENT VARIABLES: Athletes completed the tandem gait test and a gait evaluation in single/dual-task conditions during a preseason examination...
October 5, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29019867/the-effects-of-various-weighted-implements-on-baseball-swing-kinematics-in-collegiate-baseball-players
#13
Charles C Williams, Jacob R Gdovin, Samuel J Wilson, Vanessa L Cazas-Moreno, John D Eason, Elizabeth L Hoke, Charles R Allen, Chip Wade, John C Garner
The purpose of this study was to investigate the effects of different warm-up (WU) devices on bat swing parameters including maximal resultant velocity (MRV), resultant velocity at ball contact (RVBC), time difference between MRV and RVBC, bat angle at MRV, bat angle at RVBC, and perceptual differences (PD) of each WU implement utilized by National Collegiate Athletic Association (NCAA) Division-I baseball players. Fifteen varsity baseball players completed one experimental session during fall training. Retro-reflective markers were placed on the bat and tee to measure basic bat kinematics during the swing...
June 3, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28993006/promoting-sunscreen-use-and-sun-protective-practices-in-ncaa-athletes-impact-of-sunsport-educational-intervention-for-student-athletes-athletic-trainers-and-coaches
#14
Mina S Ally, Susan M Swetter, Kelsey E Hirotsu, Justin Gordon, David Kim, Ashley Wysong, Lindsy Donnelly, Shufeng Li, Kristin M Nord
BACKGROUND: Student-athletes (SAs) have an increased skin cancer risk on account of significant ultraviolet exposure; however, their sun-protective practices are suboptimal. A novel program, Stanford University Network for Sun Protection, Outreach, Research, and Teamwork (SUNSPORT), was designed to target SAs, coaches, and athletic trainers (ATs). OBJECTIVE: To measure the impact of educational intervention on sun protection beliefs and practices of SAs. METHODS: A survey of sun protection beliefs and practices was administered to National Collegiate Athletic Association athletes before and after intervention...
October 6, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28985702/descriptive-epidemiology-of-injuries-sustained-in-national-collegiate-athletic-association-men-s-and-women-s-volleyball-2013-2014-to-2014-2015
#15
Christine M Baugh, Gil S Weintraub, Andrew J Gregory, Aristarque Djoko, Thomas P Dompier, Zachary Y Kerr
BACKGROUND: There were 18,844 volleyball players in the National Collegiate Athletic Association (NCAA) in the 2014-2015 academic year. Little research has examined sex-based differences among these athletes. PURPOSE: To examine injury epidemiology in NCAA men's and women's volleyball athletes. STUDY DESIGN: Descriptive epidemiology study. LEVEL OF EVIDENCE: Level 3. METHODS: Injury surveillance data from the 2013-2014 through 2014-2015 academic years were obtained from the NCAA Injury Surveillance Program for 6 men's and 33 women's collegiate volleyball teams...
October 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28977818/malt-beverage-brand-popularity-among-youth-and-youth-appealing-advertising-content
#16
Ziming Xuan, William DeJong, Michael Siegel, Thomas F Babor
BACKGROUND: This study examined whether alcohol brands more popular among youth are more likely to have aired television advertisements that violated the alcohol industry's voluntary code by including youth-appealing content. METHODS: We obtained a complete list of 288 brand-specific beer advertisements broadcast during the National Collegiate Athletic Association (NCAA) men's and women's basketball tournaments from 1999 to 2008. All ads were rated by a panel of health professionals using a modified Delphi method to assess the presence of youth-appealing content in violation of the alcohol industry's voluntary code...
November 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/28937802/the-epidemiology-of-stress-fractures-in-collegiate-student-athletes-2004-2005-through-2013-2014-academic-years
#17
Katherine H Rizzone, Kathryn E Ackerman, Karen G Roos, Thomas P Dompier, Zachary Y Kerr
CONTEXT:   Stress fractures are injuries caused by cumulative, repetitive stress that leads to abnormal bone remodeling. Specific populations, including female athletes and endurance athletes, are at higher risk than the general athletic population. Whereas more than 460 000 individuals participate in collegiate athletics in the United States, no large study has been conducted to determine the incidence of stress fractures in collegiate athletes. OBJECTIVE:   To assess the incidence of stress fractures in National Collegiate Athletic Association (NCAA) athletes and investigate rates and patterns overall and by sport...
October 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28937785/gaining-access-to-providing-medical-care-to-male-sport-teams-the-female-athletic-trainer-perspective
#18
Alicia Pike, Stephanie M Mazerolle, Jessica L Barrett
CONTEXT:   Female athletic trainers (ATs) can face barriers to employment within the profession. Although there is evidence for an increasing percentage of women in athletic training, the portion providing medical care to male sport teams within the professional sport and collegiate settings continues to be small. OBJECTIVE:   To investigate the experiences of female ATs when seeking employment with male sport teams within the Division I setting. DESIGN:   Qualitative study...
October 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28869402/the-epidemiology-of-back-neck-spine-injuries-in-national-collegiate-athletic-association-men-s-and-women-s-ice-hockey-2009-2010-to-2014-2015
#19
Alyssa B Zupon, Zachary Y Kerr, Sara L Dalton, Thomas P Dompier, Elizabeth C Gardner
This study describes the epidemiology of back/neck/spine injuries in National Collegiate Athletic Association (NCAA) men's and women's ice hockey. Data from 66 NCAA men's and 29 women's ice hockey programmes (total of 147 and 67 team-seasons, respectively) were analysed from the NCAA Injury Surveillance Program during the 2009/2010-2014/2015 academic years. In the study period, 226 and 97 back/neck/spine injuries were reported in men and women, respectively, for injury rates of 0.56 and 0.65/1000 athlete exposures...
September 4, 2017: Research in Sports Medicine
https://www.readbyqxmd.com/read/28859810/global-substitution-of-hemeproteins-with-noncanonical-amino-acids-in-escherichia-coli-with-intact-cofactor-maturation-machinery
#20
Jan-Stefan Völler, Tuyet Mai Thi To, Hernan Biava, Beate Koksch, Nediljko Budisa
Global substitution of canonical amino acids (cAAs) with noncanonical (ncAAs) counterparts in proteins whose function is dependent on post-translational events such as cofactor binding is still a methodically challenging and difficult task as ncAA insertion generally interferes with the cofactor biosynthesis machinery. Here, we report a technology for the expression of fully substituted and functionally active cofactor-containing hemeproteins. The maturation process which yields an intact cofactor is timely separated from cAA→ncAA substitutions...
November 2017: Enzyme and Microbial Technology
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