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https://www.readbyqxmd.com/read/28323494/associations-between-thematic-content-and-industry-self-regulation-code-violations-in-beer-advertising-broadcast-during-the-u-s-ncaa-basketball-tournament
#1
Jonathan K Noel, Ziming Xuan, Thomas F Babor
BACKGROUND: Beer marketing in the United States is controlled through self-regulation, whereby the beer industry has created a marketing code and enforces its use. We performed a thematic content analysis on beer ads broadcast during a U.S. college athletic event and determined which themes are associated with violations of a self-regulated alcohol marketing code. METHODS: 289 beer ads broadcast during the U.S. NCAA Men's and Women's 1999-2008 basketball tournaments were assessed for the presence of 23 thematic content areas...
March 21, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28323071/the-central-role-of-trna-in-genetic-code-expansion
#2
REVIEW
Noah M Reynolds, Oscar Vargas-Rodriguez, Dieter Söll, Ana Crnković
BACKGROUND: The development of orthogonal translation systems (OTSs) for genetic code expansion (GCE) has allowed for the incorporation of a diverse array of non-canonical amino acids (ncAA) into proteins. Transfer RNA, the central molecule in the translation of the genetic message into proteins, plays a significant role in the efficiency of ncAA incorporation. SCOPE OF REVIEW: Here we review the biochemical basis of OTSs for genetic code expansion. We focus on the role of tRNA and discuss strategies used to engineer tRNA for the improvement of ncAA incorporation into proteins...
March 17, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28292694/asb-clinical-biomechanics-award-winner-2016-assessment-of-gaze-stability-within-24-48hours-post-concussion
#3
Nicholas G Murray, Nathan R D'Amico, Douglas Powell, Megan E Mormile, Katelyn E Grimes, Barry A Munkasy, Russell K Gore, Rebecca J Reed-Jones
BACKGROUND: Approximately 90% of athletes with concussion experience a certain degree of visual system dysfunction immediately post-concussion. Of these abnormalities, gaze stability deficits are denoted as among the most common. Little research quantitatively explores these variables post-concussion. As such, the purpose of this study was to investigate and compare gaze stability between a control group of healthy non-injured athletes and a group of athletes with concussions 24-48hours post-injury...
March 6, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28288813/a-genomically-modified-escherichia-coli-strain-carrying-an-orthogonal-e-coli-histidyl-trna-synthetase%C3%A2-trna-his-pair
#4
Markus Englert, Oscar Vargas-Rodriguez, Noah M Reynolds, Yane-Shih Wang, Dieter Söll, Takuya Umehara
BACKGROUND: Development of new aminoacyl-tRNA synthetase (aaRS)•tRNA pairs is central for incorporation of novel non-canonical amino acids (ncAAs) into proteins via genetic code expansion (GCE). The Escherichia coli and Caulobacter crescentus histidyl-tRNA synthetases (HisRS) evolved divergent mechanisms of tRNA(His) recognition that prevent their cross-reactivity. Although the E. coli HisRS•tRNA(His) pair is a good candidate for GCE, its use in C. crescentus is limited by the lack of established genetic selection methods and by the low transformation efficiency of C...
March 10, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28281095/a-national-study-on-the-effects-of-concussion-in-collegiate-athletes-and-us-military-service-academy-members-the-ncaa-dod-concussion-assessment-research-and-education-care-consortium-structure-and-methods
#5
Steven P Broglio, Michael McCrea, Thomas McAllister, Jaroslaw Harezlak, Barry Katz, Dallas Hack, Brian Hainline
BACKGROUND: The natural history of mild traumatic brain injury (TBI) or concussion remains poorly defined and no objective biomarker of physiological recovery exists for clinical use. The National Collegiate Athletic Association (NCAA) and the US Department of Defense (DoD) established the Concussion Assessment, Research and Education (CARE) Consortium to study the natural history of clinical and neurobiological recovery after concussion in the service of improved injury prevention, safety and medical care for student-athletes and military personnel...
March 9, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28277424/comparing-performance-during-morning-vs-afternoon-training-sessions-in-intercollegiate-basketball-players
#6
Aaron D Heishman, Michael A Curtis, Ethan Saliba, Robert J Hornett, Steven K Malin, Arthur L Weltman
Time of day is a key factor that influences the optimization of athletic performance. Intercollegiate coaches oftentimes hold early morning strength training sessions for a variety of factors including convenience. However, few studies have specifically investigated the effect of early morning vs. late afternoon strength training on performance indices of fatigue. This is athletically important because circadian/ultradian rhythms and alterations in sleep patterns can impact training ability. Therefore, the purpose of the present study was to examine the effects of morning vs...
March 8, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28277407/iron-deficiency-and-anemia-among-collegiate-athletes-a-retrospective-chart-review
#7
Rachel B Parks, Scott J Hetzel, M Alison Brooks
PURPOSE: To describe the prevalence of anemia among incoming female college athletes and to characterize the results and expenses of iron-related testing at one NCAA Division I institution. METHODS: In this retrospective medical record review, hemoglobin (Hgb) and ferritin (Fer) lab values were obtained for student-athletes at a single institution, 2002 - 2014. Labs were collected either as part of the pre-participation exam (PPE) for female athletes, routine screening for cross country athletes, or as needed for medical evaluation...
March 8, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28264473/future-of-the-genetic-code
#8
REVIEW
Hong Xue, J Tze-Fei Wong
The methods for establishing synthetic lifeforms with rewritten genetic codes comprising non-canonical amino acids (NCAA) in addition to canonical amino acids (CAA) include proteome-wide replacement of CAA, insertion through suppression of nonsense codon, and insertion via the pyrrolysine and selenocysteine pathways. Proteome-wide reassignments of nonsense codons and sense codons are also under development. These methods enable the application of NCAAs to enrich both fundamental and applied aspects of protein chemistry and biology...
February 28, 2017: Life
https://www.readbyqxmd.com/read/28261747/the-epidemiology-of-ncaa-men-s-lacrosse-injuries-2009-10-2014-15-academic-years
#9
Zachary Y Kerr, Adam Quigley, Susan W Yeargin, Andrew E Lincoln, James Mensch, Shane V Caswell, Thomas P Dompier
BACKGROUND: Participation in lacrosse has grown at the collegiate levels. However, little research has examined the epidemiology of collegiate men's lacrosse injuries. This study describes the epidemiology of injuries in National Collegiate Athletic Association (NCAA) men's lacrosse during the 2009/10-2014/15 academic years. METHODS: Twenty-five men's lacrosse programs provided 63 team-seasons of data for the NCAA Injury Surveillance Program (NCAA-ISP) during the 2009/10-2014/15 academic years...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28253034/playing-experience-and-position-influence-injury-risk-among-ncaa-division-i-collegiate-footballers
#10
Robert McCunn, Hugh H K Fullagar, Sean Williams, Travis J Halseth, John A Sampson, Andrew Murray
PURPOSE: American football is widely played by collegiate student-athletes throughout the United States; however, the associated injury risk is greater than in other team sports. Numerous factors likely contribute to this risk yet research identifying these risk factors is limited. The present study sought to explore the relationship between playing experience and position on injury risk within NCAA Division I collegiate footballers. METHODS: Seventy-six male collegiate student athletes within the American football program of an NCAA Division I university participated...
March 2, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28239189/pyrrolysyl-trna-synthetase-an-aminoacyl-trna-synthetase-for-genetic-code-expansion
#11
Ana Crnković, Tateki Suzuki, Dieter Söll, Noah M Reynolds
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineered aminoacyl-tRNA synthetases (aaRSs) and a cognate tRNA species to allow codon reassignment by co-translational insertion of non-canonical amino acids (ncAAs) into proteins. Introduction of such amino acids increases the chemical diversity of recombinant proteins endowing them with novel properties. Such proteins serve in sophisticated biochemical and biophysical studies both in vitro and in vivo, they may become unique biomaterials or therapeutic agents, and they afford metabolic dependence of genetically modified organisms for biocontainment purposes...
June 2016: Croatica Chemica Acta. Arhiv za Kemiju
https://www.readbyqxmd.com/read/28237511/coupling-genetic-code-expansion-and-metabolic-engineering-for-synthetic-cells
#12
REVIEW
Jan-Stefan Völler, Nediljko Budisa
Orthogonal protein translation with noncanonical amino acids (ncAAs) has become a standard method in biosciences. Whereas much effort is made to broaden the chemical space of ncAAs, only few attempts on their systematic low-cost in situ production are reported until now. The main aim is to engineer cells with newly designed biosynthetic pathways coupled with orthogonal aminoacyl-tRNA synthetase/tRNA pairs (o-pairs). These should provide cost-effective solutions to industrially relevant bio-production problems, such as peptide/protein production beyond the canonical set of natural molecules and to expand the arsenal of chemistries available for living cells...
February 23, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28230925/not-all-athletes-are-equal-but-don-t-call-me-an-exerciser-response-to-araujo-and-scharhag-2016
#13
Clare MacMahon, Lucy Parrington
Many Olympians and Paralympians would not be called athletes if what dictates this classification is fulfilling the criteria of Araujo and Scharhag (2016). Shelley Watts, Australian amateur boxer and Commonwealth gold medallist undertakes a double degree in law and sports science, something which undoubtedly takes up a considerable number of hours throughout her week (Australian Olympic Committie [AOC], 2016). There are many other athletes in similar positions - College athletes in the United States who are part of the National Collegiate Athletic Association (NCAA), for example...
February 23, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28229928/an-expanded-genetic-code-for-probing-the-role-of-electrostatics-in-enzyme-catalysis-by-vibrational-stark-spectroscopy
#14
REVIEW
Jan-Stefan Völler, Hernan Biava, Peter Hildebrandt, Nediljko Budisa
BACKGROUND: To find experimental validation for electrostatic interactions essential for catalytic reactions represents a challenge due to practical limitations in assessing electric fields within protein structures. SCOPE OF REVIEW: This review examines the applications of non-canonical amino acids (ncAAs) as genetically encoded probes for studying the role of electrostatic interactions in enzyme catalysis. MAJOR CONCLUSIONS: ncAAs constitute sensitive spectroscopic probes to detect local electric fields by exploiting the vibrational Stark effect (VSE) and thus have the potential to map the protein electrostatics...
February 14, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28225709/the-relationship-between-trunk-rotation-upper-quarter-dynamic-stability-and-pitch-velocity
#15
Garrett S Bullock, Abigail C Schmitt, Patrick Chasse, Barrett A Little, Lee H Diehl, Robert J Butler
Understanding the relationship between upper quarter mobility, dynamic stability and pitching velocity may be beneficial in elucidating underlying factors that affect pitching performance. The purpose of this study was to investigate upper trunk rotation mobility and upper quarter dynamic stability and their correlation to pitch velocity in NCAA Division I collegiate pitchers. We hypothesized that collegiate pitchers with greater upper trunk rotation mobility and upper extremity dynamic stability would exhibit higher pitching velocity...
February 21, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28210246/prospects-of-in-vivo-incorporation-of-non-canonical-amino-acids-for-the-chemical-diversification-of-antimicrobial-peptides
#16
Tobias Baumann, Jessica H Nickling, Maike Bartholomae, Andrius Buivydas, Oscar P Kuipers, Nediljko Budisa
The incorporation of non-canonical amino acids (ncAA) is an elegant way for the chemical diversification of recombinantly produced antimicrobial peptides (AMPs). Residue- and site-specific installation methods in several bacterial production hosts hold great promise for the generation of new-to-nature AMPs, and can contribute to tackle the ongoing emergence of antibiotic resistance in pathogens. Especially from a pharmacological point of view, desirable improvements span pH and protease resistance, solubility, oral availability and circulation half-life...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28146396/epidemiological-patterns-of-ankle-sprains-in-youth-high-school-and-college-football
#17
Daniel R Clifton, Rachel M Koldenhoven, Jay Hertel, James A Onate, Thomas P Dompier, Zachary Y Kerr
BACKGROUND: Variations in ankle injury rates and distributions among competition levels are unclear, but such data may help inform strategies to prevent ankle sprains during American football. PURPOSE: To describe the epidemiological patterns of ankle sprains in youth, high school (HS), and collegiate American football. STUDY DESIGN: Descriptive epidemiological study. METHODS: Data regarding youth, HS, and college football athletes were collected from 3 injury surveillance programs: (1) the Youth Football Safety Study (YFSS), (2) the National Athletic Treatment, Injury and Outcomes Network (NATION), and (3) the National Collegiate Athletic Association (NCAA) Injury Surveillance Program (ISP)...
February 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28140625/ncaa-football-off-season-training-unanswered-prayers%C3%A2-a-prayer-answered
#18
Scott Anderson
Off-season training in year-round collegiate football is purported to be performance enhancing. Absent principles of exercise physiology, excesses in sport-training regimens pose risk to the participant athletes. Since 2000, 33 National Collegiate Athletic Association (NCAA) football players have died in sport: 27 nontraumatic deaths and 6 traumatic deaths, a ratio of 4.5 nontraumatic deaths for every traumatic death. On average, 2 NCAA football players die per season. Best practices, consensus guidelines, and precautions are ignored, elevating the risk...
February 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28118030/the-epidemiology-of-severe-injuries-sustained-by-national-collegiate-athletic-association-student-athletes-2009-2010-through-2014-2015
#19
Melissa C Kay, Johna K Register-Mihalik, Aaron D Gray, Aristarque Djoko, Thomas P Dompier, Zachary Y Kerr
CONTEXT: Few researchers have described the incidence of the most severe injuries sustained by student-athletes at the collegiate level. OBJECTIVE: To describe the epidemiology of severe injuries within 25 National Collegiate Athletic Association (NCAA) sports in the 2009-2010 through 2014-2015 academic years. DESIGN: Descriptive epidemiology study. SETTING: Aggregate injury and exposure data from 25 NCAA sports. PATIENTS OR OTHER PARTICIPANTS: Collegiate student-athletes in the 2009-2010 through 2014-2015 academic years...
February 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28104718/bioorthogonal-noncanonical-amino-acid-tagging-boncat-enables-time-resolved-analysis-of-protein-synthesis-in-native-plant-tissue
#20
Weslee S Glenn, Shannon E Stone, Samuel H Ho, Michael J Sweredoski, Annie Moradian, Sonja Hess, Julia Bailey-Serres, David A Tirrell
Proteomic plasticity undergirds stress responses in plants, and understanding such responses requires accurate measurement of the extent to which proteins levels are adjusted to counter external stimuli. Here, we adapt bioorthogonal noncanonical amino acid tagging (BONCAT) to interrogate protein synthesis in vegetative Arabidopsis (Arabidopsis thaliana) seedlings. BONCAT relies on the translational incorporation of a noncanonical amino acid probe into cellular proteins. In this study, the probe is the Met surrogate azidohomoalanine (Aha), which carries a reactive azide moiety in its amino acid side chain...
March 2017: Plant Physiology
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