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Kidney transplant sugammadex

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https://www.readbyqxmd.com/read/26225497/efficacy-and-safety-of-sugammadex-in-the-reversal-of-deep-neuromuscular-blockade-induced-by-rocuronium-in-patients-with-end-stage-renal-disease-a-comparative-prospective-clinical-trial
#1
COMPARATIVE STUDY
Camila M de Souza, Maria A Tardelli, Helio Tedesco, Natalia N Garcia, Mario P Caparros, Jose A Alvarez-Gomez, Itamar S de Oliveira Junior
BACKGROUND: Renal failure affects the pharmacology of nondepolarizing neuromuscular blockers making recovery of neuromuscular function unpredictable. Sugammadex antagonises rocuronium-induced neuromuscular blockade by encapsulating rocuronium, creating a stable complex molecule that is mainly excreted by the kidneys. Previous studies suggest that sugammadex is effective in reversing moderate neuromuscular block in the presence of renal failure, but no data are available regarding reversal of profound neuromuscular block in patients with renal failure...
October 2015: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/22263406/-sugammadex-in-a-man-with-a-transplanted-kidney-a-case-report
#2
I Cordero Escobar, B Rey Martínez, R Company Teuler, A Pérez Carbonell
We report the use of sugammadex to reverse a rocuronium block in a man who had received a kidney transplant 4 years earlier. The patient was admitted for gastric non-Hodgkins lymphoma and bleeding that required surgery. Arterial hypertension, tachycardia, and frequent ventricular extrasystoles were detected. Anesthetic induction was accomplished with propofol, fentanyl, and rocuronium; intubation was uneventful. We monitored pulse oximetry, capnography, heart rate, electrocardiography, arterial pressure (invasive), cardiac output, end-systolic volume, bispectral index, temperature, and neuromuscular function...
December 2011: Revista Española de Anestesiología y Reanimación
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