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Global prevalence of CKD

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https://www.readbyqxmd.com/read/29036821/estimated-glomerular-filtration-rate-is-not-associated-with-alzheimer-s-disease-in-a-northern-ireland-cohort
#1
Euan N Paterson, Michael A Williams, Peter Passmore, Giuliana Silvestri, Tom J MacGillivray, Alexander P Maxwell, Gareth J McKay
BACKGROUND: Alzheimer's disease (AD) prevalence is increasing globally and typically progresses for several years prior to clinical presentation of dementia. Renal dysfunction and vascular disease have been reported in association with dementia in several cross-sectional and longitudinal studies, and may contribute to AD risk. Experimental and observational studies suggest amyloid-β (Aβ) clearance may be impaired in chronic kidney disease (CKD) indicating a mechanism for increased AD risk...
October 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28982165/treatment-of-canine-leishmaniasis-with-marbofloxacin-in-dogs-with-renal-disease
#2
Carmen Pineda, Escolastico Aguilera-Tejero, Maria C Morales, Silvia Belinchon-Lorenzo, Luis C Gomez-Nieto, Pablo Garcia, Julio M Martinez-Moreno, Maria E Rodriguez-Ortiz, Ignacio Lopez
Treatment of canine leishmaniasis (CanL) represents a challenge. Due to the high prevalence of renal disease associated to CanL, it is important to find an effective drug that does not damage the kidneys. Marbofloxacin has been shown to be effective and well tolerated in non-azotemic dogs with leishmaniasis. To evaluate the safety and efficacy of marbofloxacin in dogs with leishmaniasis and decreased renal function, 28 dogs suffering from leishmaniasis and chronic kidney disease (CKD) were treated with oral marbofloxacin at 2 mg/Kg/day for 28 days...
2017: PloS One
https://www.readbyqxmd.com/read/28851783/prevalence-incidence-and-associated-mortality-of-cardiovascular-disease-in-patients-with-chronic-kidney-disease-in-low-and-middle-income-countries-a-protocol-for-a-systematic-review-and-meta-analysis
#3
Mazou N Temgoua, Celestin Danwang, Valirie Ndip Agbor, Jean Jacques Noubiap
INTRODUCTION: Chronic kidney disease (CKD) is a global public health problem, with cardiovascular disease (CVD) being the major cause of mortality in these patients. Despite a high burden of CKD among patients in low/middle-income countries (LMICs), evidence on the distribution of CVD among these patients is lacking. This review seeks to determine the prevalence, incidence and mortality risks of CVD in patients with CKD in LMICs. METHODS AND ANALYSIS: A systematic search of Medline, Scopus, Embase, Cumulative Index of Nursing and Allied Health and WHO Global Health Library databases for published studies reporting on the prevalence, incidence and associated mortality risk of CVD in CKD patients in LMICs will be conducted from 1 May 1987 to 1 July 2017 with no language restriction...
August 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28842286/incidence-and-risk-factors-of-acute-kidney-injury-in-the-japanese-trauma-population-a-prospective-cohort-study
#4
Jun Fujinaga, Akira Kuriyama, Noriaki Shimada
INTRODUCTION: Previous studies have reported the prevalence and risk factors of acute kidney injury (AKI) in relatively young trauma patients. The aims of this study were to identify the prevalence and risk factors of AKI among older Japanese trauma patients. METHODS: We conducted a prospective observational study in the 8-bed intensive care unit (ICU) of a Japanese tertiary-care hospital. Participants comprised trauma patients aged 18 years or older admitted to the ICU...
August 15, 2017: Injury
https://www.readbyqxmd.com/read/28832275/association-between-obesity-and-chronic-kidney-disease-defined-by-both-glomerular-filtration-rate-and-albuminuria-in-korean-adults
#5
Yoon Ji Kim, Seun Deuk Hwang, Tae Jung Oh, Kyoung Min Kim, Hak Chul Jang, Heejin Kimm, Hyeon Chang Kim, Sun Ha Jee, Soo Lim
BACKGROUND: Chronic kidney disease (CKD) has often been defined based on glomerular filtration rate (GFR) alone. The Kidney Disease: Improving Global Outcomes guideline highlights albuminuria in the CKD definition. Thus, we investigated the association between obesity and CKD, as defined by both GFR and albuminuria, in Korean adults. METHODS: We used Korea National Health and Nutrition Examination Survey 2011-2014 data (N = 19,331, ≥19 years old) representing the national Korean population...
October 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28776240/diabetes-mellitus-and-chronic-kidney-disease-in-the-eastern-mediterranean-region-findings-from-the-global-burden-of-disease-2015-study
#6
Ali H Mokdad
OBJECTIVES: We used findings from the Global Burden of Disease 2015 study to update our previous publication on the burden of diabetes and chronic kidney disease due to diabetes (CKD-DM) during 1990-2015. METHODS: We extracted GBD 2015 estimates for prevalence, mortality, and disability-adjusted life years (DALYs) of diabetes (including burden of low vision due to diabetes, neuropathy, and amputations and CKD-DM for 22 countries of the EMR from the GBD visualization tools...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28755901/protein-energy-wasting-syndrome-in-advanced-chronic-kidney-disease-prevalence-and-specific-clinical-characteristics
#7
Almudena Pérez-Torres, M Elena González Garcia, Belén San José-Valiente, M Auxiliadora Bajo Rubio, Olga Celadilla Diez, Ana M López-Sobaler, Rafael Selgas
INTRODUCTION: Protein-energy wasting (PEW) is associated with increased mortality and differs depending on the chronic kidney disease (CKD) stage and the dialysis technique. The prevalence in non-dialysis patients is understudied and ranges from 0 to 40.8%. OBJECTIVE: To evaluate the nutritional status of a group of Spanish advanced CKD patients by PEW criteria and subjective global assessment (SGA). PATIENTS AND METHODS: Cross-sectional study of 186 patients (101 men) with a mean age of 66...
July 26, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28724362/prevalence-of-chronic-kidney-disease-in-peruvian-primary-care-setting
#8
Percy Herrera-Añazco, Alvaro Taype-Rondan, María Lazo-Porras, E Alberto Quintanilla, Victor Manuel Ortiz-Soriano, Adrian V Hernandez
BACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. METHODS: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO)...
July 19, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28721320/detection-of-chronic-kidney-disease-by-using-different-equations-of-glomerular-filtration-rate-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-analysis
#9
Sojib Bin Zaman
Introduction Chronic kidney disease (CKD) is a global threat due to its high mortality. It is essential to know the actual magnitude of diabetic CKD to design a specific management program. However, there is limited knowledge regarding the most suitable equation to measure CKD in patients with Type 2 diabetes mellitus (T2DM). This paper aimed to analyze estimated glomerular filtration rate (eGFR) based on different equations to detect the CKD among T2DM.  Methods A hospital-based cross-sectional study was carried out, and a clinical registry was used to collect 4,042 T2DM patients from a large district hospital in Northeast Thailand...
June 14, 2017: Curēus
https://www.readbyqxmd.com/read/28680359/screening-for-chronic-kidney-disease-in-adult-males-in-vojvodina-a-cross-sectional-study
#10
Velibor Čabarkapa, Branislava Ilinčić, Mirjana Đerić, Isidora Radosavkić, Mirko Šipovac, Jan Sudji, Veljko Petrović
BACKGROUND: Chronic kidney disease (CKD) is one of the most significant global health problems accompanied by numerous complicatons, with constant increase in the number of affected people. This number is much higher in early phases of disease and patients are mostly asymptomatic, so early detection of CKD is crucial. The aim was examination of the prevalence of CKD in the general population of males in Vojvodina, based on estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR), and exploring the determinants and awareness of CKD...
April 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28654798/the-impact-of-gut-microbiota-on-kidney-function-and-pathogenesis
#11
REVIEW
Fariba Mahmoodpoor, Yalda Rahbar Saadat, Abolfazl Barzegari, Mohammadreza Ardalan, Sepideh Zununi Vahed
Chronic kidney diseases (CKDs) are a global health problem. Besides diverse leading reasons in initiation and progression of CKDs, it is evident that they might largely originate from changes in the gut microbial community (microbiota). Mounting evidence indicates that a bidirectional relationship exists between host and microbiome in humans and animals with CKDs. Changes in the microbiota composition and structure (dysbiosis) produce excessive amounts of uremic toxins (e.g. indoxyl sulfate, p-cresyl sulfate and trimethylamine-N-oxide) but less reno-protective metabolites that are implicated in oxidative stress, uremia, inflammation, deterioration of kidney function, kidney diseases progression, a higher prevalence of cardiovascular risk, and mortality in patients with CKD...
September 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28617483/epidemiology-of-chronic-kidney-disease-think-at-least-twice
#12
Pierre Delanaye, Richard J Glassock, Marc E De Broe
The introduction of the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines has substantially contributed to the early detection of different stages of chronic kidney disease (CKD). Several recent studies from different parts of the world mention a CKD prevalence of between 8 and 13%. There are several reasons the CKD prevalence found in a study of a particular population is clearly overestimated. The structure of the population pyramid (young or older age) of the study sample may result in high or low CKD prevalence...
June 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28602847/non-proteinuric-diabetic-nephropathy-is-the-main-cause-of-chronic-kidney-disease-results-of-a-general-population-survey-in-spain
#13
N R Robles, J Villa, F J Felix, D Fernandez-Berges, L Lozano
BACKGROUND: Diabetic nephropathy traditionally produces significant proteinuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. The current study evaluated the impact of diabetes mellitus on the prevalence of renal disease in general population. METHODOLOGY: Data from of the HERMEX survey, an observational, cross sectional, population based study were used. The final sample included 2813 subjects (mean age 51...
June 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28467510/prevalence-and-determinants-of-chronic-kidney-disease-in-northeast-of-iran-results-of-the-golestan-cohort-study
#14
Sadaf G Sepanlou, Hamid Barahimi, Iraj Najafi, Farin Kamangar, Hossein Poustchi, Ramin Shakeri, Monir Sadat Hakemi, Akram Pourshams, Masoud Khoshnia, Abdolsamad Gharravi, Behrooz Broumand, Ali Nobakht-Haghighi, Kamyar Kalantar-Zadeh, Reza Malekzadeh
BACKGROUND: The burden of chronic kidney disease (CKD) is increasing globally in particular in fast emerging economies such as Iran. Population-based studies on prevalence of CKD in Iran are scarce. The objective of the current study was to explore the prevalence and determinants of CKD in the setting of Golestan Cohort Study (GCS), the largest prospective cohort in the Middle East. METHODS: In this observational study, 11,409 participants enrolled in the second phase of GCS were included...
2017: PloS One
https://www.readbyqxmd.com/read/28434761/improvement-in-nutritional-status-in-patients-with-chronic-kidney-disease-4-by-a-nutrition-education-program-with-no-impact-on-renal-function-and-determined-by-male-sex
#15
Almudena Pérez-Torres, Elena González Garcia, Helena Garcia-Llana, Gloria Del Peso, Ana María López-Sobaler, Rafael Selgas
OBJECTIVE: Protein-energy wasting (PEW) is associated with increased morbidity and mortality and a rapid deterioration of kidney function in patients with chronic kidney disease (CKD). However, there is little information regarding the effect of nutrition intervention. The aims of this study were to evaluate the efficacy and safety of a nutrition education program (NEP) in patients with nondialysis dependent CKD (NDD-CKD), based on the diagnostic criteria for PEW proposed by the International Society of Renal Nutrition and Metabolism...
April 20, 2017: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/28421193/molecular-abnormalities-underlying-bone-fragility-in-chronic-kidney-disease
#16
REVIEW
Yoshiko Iwasaki, Junichiro James Kazama, Masafumi Fukagawa
Prevention of bone fractures is one goal of therapy for patients with chronic kidney disease-mineral and bone disorder (CKD-MBD), as indicated by the Kidney Disease: Improving Global Outcomes guidelines. CKD patients, including those on hemodialysis, are at higher risk for fractures and fracture-related death compared to people with normal kidney function. However, few clinicians focus on this issue as it is very difficult to estimate bone fragility. Additionally, uremia-related bone fragility has a more complicated pathological process compared to osteoporosis...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28408440/global-cardiovascular-and-renal-outcomes-of-reduced-gfr
#17
Bernadette Thomas, Kunihiro Matsushita, Kalkidan Hassen Abate, Ziyad Al-Aly, Johan Ärnlöv, Kei Asayama, Robert Atkins, Alaa Badawi, Shoshana H Ballew, Amitava Banerjee, Lars Barregård, Elizabeth Barrett-Connor, Sanjay Basu, Aminu K Bello, Isabela Bensenor, Jaclyn Bergstrom, Boris Bikbov, Christopher Blosser, Hermann Brenner, Juan-Jesus Carrero, Steve Chadban, Massimo Cirillo, Monica Cortinovis, Karen Courville, Lalit Dandona, Rakhi Dandona, Kara Estep, João Fernandes, Florian Fischer, Caroline Fox, Ron T Gansevoort, Philimon N Gona, Orlando M Gutierrez, Samer Hamidi, Sarah Wulf Hanson, Jonathan Himmelfarb, Simerjot K Jassal, Sun Ha Jee, Vivekanand Jha, Aida Jimenez-Corona, Jost B Jonas, Andre Pascal Kengne, Yousef Khader, Young-Ho Khang, Yun Jin Kim, Barbara Klein, Ronald Klein, Yoshihiro Kokubo, Dhaval Kolte, Kristine Lee, Andrew S Levey, Yongmei Li, Paulo Lotufo, Hassan Magdy Abd El Razek, Walter Mendoza, Hirohito Metoki, Yejin Mok, Isao Muraki, Paul M Muntner, Hiroyuki Noda, Takayoshi Ohkubo, Alberto Ortiz, Norberto Perico, Kevan Polkinghorne, Rajaa Al-Radaddi, Giuseppe Remuzzi, Gregory Roth, Dietrich Rothenbacher, Michihiro Satoh, Kai-Uwe Saum, Monika Sawhney, Ben Schöttker, Anoop Shankar, Michael Shlipak, Diego Augusto Santos Silva, Hideaki Toyoshima, Kingsley Ukwaja, Mitsumasa Umesawa, Stein Emil Vollset, David G Warnock, Andrea Werdecker, Kazumasa Yamagishi, Yuichiro Yano, Naohiro Yonemoto, Maysaa El Sayed Zaki, Mohsen Naghavi, Mohammad H Forouzanfar, Christopher J L Murray, Josef Coresh, Theo Vos
The burden of premature death and health loss from ESRD is well described. Less is known regarding the burden of cardiovascular disease attributable to reduced GFR. We estimated the prevalence of reduced GFR categories 3, 4, and 5 (not on RRT) for 188 countries at six time points from 1990 to 2013. Relative risks of cardiovascular outcomes by three categories of reduced GFR were calculated by pooled random effects meta-analysis. Results are presented as deaths for outcomes of cardiovascular disease and ESRD and as disability-adjusted life years for outcomes of cardiovascular disease, GFR categories 3, 4, and 5, and ESRD...
July 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/28380639/why-overestimate-or-underestimate-chronic-kidney-disease-when-correct-estimation-is-possible
#18
Marc E De Broe, Mohamed Benghanem Gharbi, Mohamed Zamd, Monique Elseviers
There is no doubt that the introduction of the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines 14 years ago, and their subsequent updates, have substantially contributed to the early detection of different stages of chronic kidney disease (CKD). Several recent studies from different parts of the world mention a CKD prevalence of 8-13%. However, some editorials and reviews have begun to describe the weaknesses of a substantial number of studies. Maremar (maladies rénales chroniques au Maroc) is a recently published prevalence study of CKD, hypertension, diabetes and obesity in a randomized, representative and high response rate (85%) sample of the adult population of Morocco that strictly applied the KDIGO guidelines...
April 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28367165/frequency-of-hepatitis-c-in-hospitalized-patients-with-chronic-kidney-disease
#19
Salman Tahir Shafi, Muhammad Zaigham Hassan, Mohammed Saleem, Roshina Anjum, Wajid Abdullah, Tahir Shafi
BACKGROUND AND OBJECTIVES: Hepatitis C and chronic kidney disease (CKD) are major global health problems and are highly prevalent in Pakistan. There is limited information on prevalence of hepatitis C in patients with CKD not yet on dialysis. The objective of this study was to determine the frequency of hepatitis C in hospitalized chronic kidney disease patients at a tertiary care center in Pakistan. METHODS: The study design was cross-sectional in nature. Patients between ages of 20-80 years with CKD not previously on renal replacement therapy and who were admitted to nephrology ward at a tertiary care facility were included...
January 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28293304/the-burden-of-diabetes-and-hyperglycemia-in-brazil-past-and-present-findings-from-the-global-burden-of-disease-study-2015
#20
Bruce Bartholow Duncan, Maria Inês Schmidt, Ewerton Cousin, Maziar Moradi-Lakeh, Valéria Maria de Azeredo Passos, Elisabeth Barboza França, Fátima Marinho, Ali H Mokdad
BACKGROUND: Diabetes, hyperglycemia, and their complications are a growing problem in Brazil. However, no comprehensive picture of this disease burden has yet been presented to date. METHODS: We used Global Burden of Disease 2015 data to characterize diabetes prevalence, incidence and risk factors from 1990 to 2015 in Brazil. Additionally, we provide mortality, years of life lost prematurely (YLL), years of life lived with disability (YLD) and disability-adjusted life years (DALYs) lost due to diabetes, as well as similar data for chronic kidney disease (CKD) due to diabetes and, as an overall summary measure, for hyperglycemia, the latter expressed as high fasting plasma glucose (HFPG)...
2017: Diabetology & Metabolic Syndrome
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