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Global prevalence of CKD

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https://www.readbyqxmd.com/read/29221436/prevalence-and-related-risk-factors-of-chronic-kidney-disease-among-adults-in-luxembourg-evidence-from-the-observation-of-cardiovascular-risk-factors-oriscav-lux-study
#1
Ala'a Alkerwi, Nicolas Sauvageot, Illiasse El Bahi, Charles Delagardelle, Jean Beissel, Stephanie Noppe, Paul J Roderick, Jennifer S Mindell, Saverio Stranges
BACKGROUND: Evidence on stages of renal impairment and related risk factors in Luxembourg is lacking. This study aimed to assess the prevalence of chronic kidney disease (CKD) and identify potential correlates among the general population, using the recent definition suggested by the Kidney Disease Improving Global Outcomes guidelines. METHODS: Data analysed from 1361 participants aged 18-69 years, enrolled in the Observation of Cardiovascular Risk Factors in Luxembourg (ORISCAV-LUX) study, 2007-08...
December 8, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29208626/the-effect-of-extended-release-niacin-on-markers-of-mineral-metabolism-in-ckd
#2
Rakesh Malhotra, Ronit Katz, Andrew Hoofnagle, Andrew Bostom, Dena E Rifkin, Ruth Mcbride, Jeffrey Probstfield, Geoffrey Block, Joachim H Ix
BACKGROUND AND OBJECTIVES: Niacin downregulates intestinal sodium-dependent phosphate transporter 2b expression and reduces intestinal phosphate transport. Short-term studies have suggested that niacin lowers serum phosphate concentrations in patients with CKD and ESRD. However, the long-term effects of niacin on serum phosphate and other mineral markers are unknown. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: The Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Trial was a randomized, double-blind, placebo-controlled trial testing extended release niacin in persons with prevalent cardiovascular disease...
December 5, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29164753/prevalence-of-left-ventricular-systolic-dysfunction-in-pre-dialysis-and-dialysis-patients-with-preserved-left-ventricular-ejection-fraction
#3
Liselotte C R Hensen, Kathleen Goossens, Victoria Delgado, Rachid Abou, Joris I Rotmans, J Wouter Jukema, Jeroen J Bax
AIMS: Patients with chronic kidney disease (CKD) have an excess of cardiovascular morbidity and mortality, with heart failure (HF) being particularly frequent. Reduced left ventricular ejection fraction (LVEF) defines left ventricular (LV) systolic dysfunction and is associated with poor prognosis. However, CKD patients may have HF symptoms with preserved LVEF. In this subgroup of patients, two-dimensional speckle tracking echocardiography can detect LV systolic dysfunction by analysing LV myocardial deformation...
November 21, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29154722/association-of-kidney-function-and-waist-circumference-with-uric-acid-levels-in-south-africans
#4
Nomandla Daphne Madala, Thozama Dubula, Alain Guy Honoré Assounga, Saraladevi Naicker
BACKGROUND: Recent evidence that hyperuricemia is associated with incident chronic kidney disease (CKD) provides a potential therapeutic target for CKD that has not been explored in Africans. With hyperuricemia and gout increasing globally, we sought to determine their prevalence in South Africans with varying kidney function levels. METHODS: This was a cross-sectional study of ambulatory adult patients presenting at a General Internal Medicine Outpatients Clinic between September 2012 and March 2014...
November 20, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29091928/relationship-between-educational-and-occupational-levels-and-chronic-kidney-disease-in-a-multi-ethnic-sample-the-helius-study
#5
David N Adjei, Karien Stronks, Dwomoa Adu, Marieke B Snijder, Pietro A Modesti, Ron J G Peters, Liffert Vogt, Charles Agyemang
BACKGROUND: Ethnic minority groups in high-income countries are disproportionately affected by Chronic Kidney Disease (CKD) for reasons that are unclear. We assessed the association of educational and occupational levels with CKD in a multi-ethnic population. Furthermore, we assessed to what extent ethnic inequalities in the prevalence of CKD were accounted for by educational and occupational levels. METHODS: Cross-sectional analysis of baseline data from the Healthy Life in an Urban Setting (HELIUS) study of 21,433 adults (4,525 Dutch, 3,027 South-Asian Surinamese, 4,105 African Surinamese, 2,314 Ghanaians, 3,579 Turks, and 3,883 Moroccans) aged 18 to 70 years living in Amsterdam, the Netherlands...
2017: PloS One
https://www.readbyqxmd.com/read/29062340/biochemical-markers-of-mineral-bone-disorder-in-south-african-patients-on-maintenance-haemodialysis
#6
Bala Waziri, Raquel Duarte, Saraladevi Naicker
BACKGROUND AND OBJECTIVE: Despite the high mortality and morbidity associated with abnormalities in mineral and bone metabolism in haemodialysis patients, there is limited data on the pattern of mineral bone disorder in African CKD population. Therefore, the purpose of this study was to describe the pattern of mineral bone disease by evaluating biochemical parameters in patients on maintenance haemodialysis (MHD). METHODS: We evaluated the serum/plasma intact parathyroid hormone (iPTH), corrected calcium, phosphate, total alkaline phosphatase (TALP) and 25 -OH vitamin D levels of two hundred and seven patients undergoing MHD at two dialysis centers in Johannesburg...
June 2017: African Health Sciences
https://www.readbyqxmd.com/read/29036821/estimated-glomerular-filtration-rate-is-not-associated-with-alzheimer-s-disease-in-a-northern-ireland-cohort
#7
Euan N Paterson, Michael A Williams, Peter Passmore, Giuliana Silvestri, Tom J MacGillivray, Alexander P Maxwell, Gareth J McKay
BACKGROUND: Alzheimer's disease (AD) prevalence is increasing globally and typically progresses for several years prior to clinical presentation of dementia. Renal dysfunction and vascular disease have been reported in association with dementia in several cross-sectional and longitudinal studies, and may contribute to AD risk. Experimental and observational studies suggest amyloid-β (Aβ) clearance may be impaired in chronic kidney disease (CKD) indicating a mechanism for increased AD risk...
October 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28982165/treatment-of-canine-leishmaniasis-with-marbofloxacin-in-dogs-with-renal-disease
#8
Carmen Pineda, Escolastico Aguilera-Tejero, Maria C Morales, Silvia Belinchon-Lorenzo, Luis C Gomez-Nieto, Pablo Garcia, Julio M Martinez-Moreno, Maria E Rodriguez-Ortiz, Ignacio Lopez
Treatment of canine leishmaniasis (CanL) represents a challenge. Due to the high prevalence of renal disease associated to CanL, it is important to find an effective drug that does not damage the kidneys. Marbofloxacin has been shown to be effective and well tolerated in non-azotemic dogs with leishmaniasis. To evaluate the safety and efficacy of marbofloxacin in dogs with leishmaniasis and decreased renal function, 28 dogs suffering from leishmaniasis and chronic kidney disease (CKD) were treated with oral marbofloxacin at 2 mg/Kg/day for 28 days...
2017: PloS One
https://www.readbyqxmd.com/read/28851783/prevalence-incidence-and-associated-mortality-of-cardiovascular-disease-in-patients-with-chronic-kidney-disease-in-low-and-middle-income-countries-a-protocol-for-a-systematic-review-and-meta-analysis
#9
Mazou N Temgoua, Celestin Danwang, Valirie Ndip Agbor, Jean Jacques Noubiap
INTRODUCTION: Chronic kidney disease (CKD) is a global public health problem, with cardiovascular disease (CVD) being the major cause of mortality in these patients. Despite a high burden of CKD among patients in low/middle-income countries (LMICs), evidence on the distribution of CVD among these patients is lacking. This review seeks to determine the prevalence, incidence and mortality risks of CVD in patients with CKD in LMICs. METHODS AND ANALYSIS: A systematic search of Medline, Scopus, Embase, Cumulative Index of Nursing and Allied Health and WHO Global Health Library databases for published studies reporting on the prevalence, incidence and associated mortality risk of CVD in CKD patients in LMICs will be conducted from 1 May 1987 to 1 July 2017 with no language restriction...
August 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28842286/incidence-and-risk-factors-of-acute-kidney-injury-in-the-japanese-trauma-population-a-prospective-cohort-study
#10
Jun Fujinaga, Akira Kuriyama, Noriaki Shimada
INTRODUCTION: Previous studies have reported the prevalence and risk factors of acute kidney injury (AKI) in relatively young trauma patients. The aims of this study were to identify the prevalence and risk factors of AKI among older Japanese trauma patients. METHODS: We conducted a prospective observational study in the 8-bed intensive care unit (ICU) of a Japanese tertiary-care hospital. Participants comprised trauma patients aged 18 years or older admitted to the ICU...
October 2017: Injury
https://www.readbyqxmd.com/read/28832275/association-between-obesity-and-chronic-kidney-disease-defined-by-both-glomerular-filtration-rate-and-albuminuria-in-korean-adults
#11
Yoon Ji Kim, Seun Deuk Hwang, Tae Jung Oh, Kyoung Min Kim, Hak Chul Jang, Heejin Kimm, Hyeon Chang Kim, Sun Ha Jee, Soo Lim
BACKGROUND: Chronic kidney disease (CKD) has often been defined based on glomerular filtration rate (GFR) alone. The Kidney Disease: Improving Global Outcomes guideline highlights albuminuria in the CKD definition. Thus, we investigated the association between obesity and CKD, as defined by both GFR and albuminuria, in Korean adults. METHODS: We used Korea National Health and Nutrition Examination Survey 2011-2014 data (N = 19,331, ≥19 years old) representing the national Korean population...
October 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/28776240/diabetes-mellitus-and-chronic-kidney-disease-in-the-eastern-mediterranean-region-findings-from-the-global-burden-of-disease-2015-study
#12
Ali H Mokdad
OBJECTIVES: We used findings from the Global Burden of Disease 2015 study to update our previous publication on the burden of diabetes and chronic kidney disease due to diabetes (CKD-DM) during 1990-2015. METHODS: We extracted GBD 2015 estimates for prevalence, mortality, and disability-adjusted life years (DALYs) of diabetes (including burden of low vision due to diabetes, neuropathy, and amputations and CKD-DM for 22 countries of the EMR from the GBD visualization tools...
August 3, 2017: International Journal of Public Health
https://www.readbyqxmd.com/read/28755901/protein-energy-wasting-syndrome-in-advanced-chronic-kidney-disease-prevalence-and-specific-clinical-characteristics
#13
Almudena Pérez-Torres, M Elena González Garcia, Belén San José-Valiente, M Auxiliadora Bajo Rubio, Olga Celadilla Diez, Ana M López-Sobaler, Rafael Selgas
INTRODUCTION: Protein-energy wasting (PEW) is associated with increased mortality and differs depending on the chronic kidney disease (CKD) stage and the dialysis technique. The prevalence in non-dialysis patients is understudied and ranges from 0 to 40.8%. OBJECTIVE: To evaluate the nutritional status of a group of Spanish advanced CKD patients by PEW criteria and subjective global assessment (SGA). PATIENTS AND METHODS: Cross-sectional study of 186 patients (101 men) with a mean age of 66...
July 26, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28724362/prevalence-of-chronic-kidney-disease-in-peruvian-primary-care-setting
#14
Percy Herrera-Añazco, Alvaro Taype-Rondan, María Lazo-Porras, E Alberto Quintanilla, Victor Manuel Ortiz-Soriano, Adrian V Hernandez
BACKGROUND: Chronic Kidney Disease (CKD) is a worldwide public health problem. There are few studies in Latin America, especially in primary care settings. Our objective was to determine the prevalence, stages, and associated factors of CKD in primary care setting. METHODS: We did a retrospective secondary analysis of a database from the Diabetes and Hypertension Primary Care Center of the Peruvian Social Security System (EsSalud) in Lima, Peru. We defined CKD as the presence of eGFR <60 mL/min and/or albuminuria >30 mg/day in 24 h, according to Kidney Disease: Improving Global Outcomes (KDIGO)...
July 19, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28721320/detection-of-chronic-kidney-disease-by-using-different-equations-of-glomerular-filtration-rate-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-analysis
#15
Sojib Bin Zaman
Introduction Chronic kidney disease (CKD) is a global threat due to its high mortality. It is essential to know the actual magnitude of diabetic CKD to design a specific management program. However, there is limited knowledge regarding the most suitable equation to measure CKD in patients with Type 2 diabetes mellitus (T2DM). This paper aimed to analyze estimated glomerular filtration rate (eGFR) based on different equations to detect the CKD among T2DM.  Methods A hospital-based cross-sectional study was carried out, and a clinical registry was used to collect 4,042 T2DM patients from a large district hospital in Northeast Thailand...
June 14, 2017: Curēus
https://www.readbyqxmd.com/read/28680359/screening-for-chronic-kidney-disease-in-adult-males-in-vojvodina-a-cross-sectional-study
#16
Velibor Čabarkapa, Branislava Ilinčić, Mirjana Đerić, Isidora Radosavkić, Mirko Šipovac, Jan Sudji, Veljko Petrović
BACKGROUND: Chronic kidney disease (CKD) is one of the most significant global health problems accompanied by numerous complicatons, with constant increase in the number of affected people. This number is much higher in early phases of disease and patients are mostly asymptomatic, so early detection of CKD is crucial. The aim was examination of the prevalence of CKD in the general population of males in Vojvodina, based on estimated glomerular filtration rate (eGFR) and urine albumin/creatinine ratio (ACR), and exploring the determinants and awareness of CKD...
April 2017: Journal of Medical Biochemistry
https://www.readbyqxmd.com/read/28654798/the-impact-of-gut-microbiota-on-kidney-function-and-pathogenesis
#17
REVIEW
Fariba Mahmoodpoor, Yalda Rahbar Saadat, Abolfazl Barzegari, Mohammadreza Ardalan, Sepideh Zununi Vahed
Chronic kidney diseases (CKDs) are a global health problem. Besides diverse leading reasons in initiation and progression of CKDs, it is evident that they might largely originate from changes in the gut microbial community (microbiota). Mounting evidence indicates that a bidirectional relationship exists between host and microbiome in humans and animals with CKDs. Changes in the microbiota composition and structure (dysbiosis) produce excessive amounts of uremic toxins (e.g. indoxyl sulfate, p-cresyl sulfate and trimethylamine-N-oxide) but less reno-protective metabolites that are implicated in oxidative stress, uremia, inflammation, deterioration of kidney function, kidney diseases progression, a higher prevalence of cardiovascular risk, and mortality in patients with CKD...
September 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28617483/epidemiology-of-chronic-kidney-disease-think-at-least-twice
#18
Pierre Delanaye, Richard J Glassock, Marc E De Broe
The introduction of the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines has substantially contributed to the early detection of different stages of chronic kidney disease (CKD). Several recent studies from different parts of the world mention a CKD prevalence of between 8 and 13%. There are several reasons the CKD prevalence found in a study of a particular population is clearly overestimated. The structure of the population pyramid (young or older age) of the study sample may result in high or low CKD prevalence...
June 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/28602847/non-proteinuric-diabetic-nephropathy-is-the-main-cause-of-chronic-kidney-disease-results-of-a-general-population-survey-in-spain
#19
N R Robles, J Villa, F J Felix, D Fernandez-Berges, L Lozano
BACKGROUND: Diabetic nephropathy traditionally produces significant proteinuria prior to the development of renal impairment. However, this clinical paradigm has recently been questioned. The current study evaluated the impact of diabetes mellitus on the prevalence of renal disease in general population. METHODOLOGY: Data from of the HERMEX survey, an observational, cross sectional, population based study were used. The final sample included 2813 subjects (mean age 51...
June 3, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28467510/prevalence-and-determinants-of-chronic-kidney-disease-in-northeast-of-iran-results-of-the-golestan-cohort-study
#20
Sadaf G Sepanlou, Hamid Barahimi, Iraj Najafi, Farin Kamangar, Hossein Poustchi, Ramin Shakeri, Monir Sadat Hakemi, Akram Pourshams, Masoud Khoshnia, Abdolsamad Gharravi, Behrooz Broumand, Ali Nobakht-Haghighi, Kamyar Kalantar-Zadeh, Reza Malekzadeh
BACKGROUND: The burden of chronic kidney disease (CKD) is increasing globally in particular in fast emerging economies such as Iran. Population-based studies on prevalence of CKD in Iran are scarce. The objective of the current study was to explore the prevalence and determinants of CKD in the setting of Golestan Cohort Study (GCS), the largest prospective cohort in the Middle East. METHODS: In this observational study, 11,409 participants enrolled in the second phase of GCS were included...
2017: PloS One
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