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https://www.readbyqxmd.com/read/28929496/a-methylome-wide-association-study-of-trajectories-of-oppositional-defiant-behaviors-and-biological-overlap-with-attention-deficit-hyperactivity-disorder
#1
Edward D Barker, Esther Walton, Charlotte A M Cecil, Richard Rowe, Sara R Jaffee, Barbara Maughan, Thomas G O'Connor, Argyris Stringaris, Alan J Meehan, Wendy McArdle, Caroline L Relton, Tom R Gaunt
In 671 mother-child (49% male) pairs from an epidemiological birth cohort, we investigated (a) prospective associations between DNA methylation (at birth) and trajectories (ages 7-13) of oppositional defiant disorder (ODD), and the ODD subdimensions of irritable and headstrong; (b) common biological pathways, indexed by DNA methylation, between ODD trajectories and attention deficit hyperactivity disorder (ADHD); (c) genetic influence on DNA methylation; and (d) prenatal risk exposure associations. Methylome-wide significant associations were identified for the ODD and headstrong, but not for irritable...
September 20, 2017: Child Development
https://www.readbyqxmd.com/read/28914082/characterizing-psychiatric-comorbidity-in-children-with-autism-spectrum-disorder-receiving-publicly-funded-mental-health-services
#2
Lauren Brookman-Frazee, Nicole Stadnick, Colby Chlebowski, Mary Baker-Ericzén, William Ganger
Publicly funded mental health programs play a significant role in serving children with autism spectrum disorder. Understanding patterns of psychiatric comorbidity for this population within mental health settings is important to implement appropriately tailored interventions. This study (1) describes patterns of psychiatric comorbidity in children with autism spectrum disorder who present to mental health services with challenging behaviors and (2) identifies child characteristics associated with comorbid conditions...
September 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/28911901/structural-brain-abnormalities-of-attention-deficit-hyperactivity-disorder-with-oppositional-defiant-disorder
#3
Siri D S Noordermeer, Marjolein Luman, Corina U Greven, Kim Veroude, Stephen V Faraone, Catharina A Hartman, Pieter J Hoekstra, Barbara Franke, Jan K Buitelaar, Dirk J Heslenfeld, Jaap Oosterlaan
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is associated with structural abnormalities in total gray matter, basal ganglia, and cerebellum. Findings of structural abnormalities in frontal and temporal lobes, amygdala, and insula are less consistent. Remarkably, the impact of comorbid oppositional defiant disorder (ODD) (comorbidity rates up to 60%) on these neuroanatomical differences is scarcely studied, while ODD (in combination with conduct disorder) has been associated with structural abnormalities of the frontal lobe, amygdala, and insula...
July 21, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28852240/effects-of-family-structure-on-mental-health-of-children-a-preliminary-study
#4
Aniruddh Prakash Behere, Pravesh Basnet, Pamela Campbell
BACKGROUND: To find any association between family structure and rates of hospitalization as an indicator for behavior problems in children. METHODS: Retrospective chart review of 154 patients who were admitted to the preadolescent unit at Lincoln Prairie Behavioral Health Center between July and December 2012. RESULTS: We found that only 11% of children came from intact families living with biological parents while 89% had some kind of disruption in their family structure...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28845711/does-anxiety-modify-the-risk-for-or-severity-of-conduct-problems-among-children-with-co-occurring-adhd-categorical-and-dimensional-and-analyses
#5
Jeffrey S Danforth, Leonard A Doerfler, Daniel F Connor
OBJECTIVE: The goal was to examine whether anxiety modifies the risk for, or severity of, conduct problems in children with ADHD. METHOD: Assessment included both categorical and dimensional measures of ADHD, anxiety, and conduct problems. Analyses compared conduct problems between children with ADHD features alone versus children with co-occurring ADHD and anxiety features. RESULTS: When assessed by dimensional rating scales, results showed that compared with children with ADHD alone, those children with ADHD co-occurring with anxiety are at risk for more intense conduct problems...
August 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28838580/trauma-exposure-and-externalizing-disorders-in-adolescents-results-from-the-national-comorbidity-survey-adolescent-supplement
#6
Hannah Carliner, Dahsan Gary, Katie A McLaughlin, Katherine M Keyes
OBJECTIVE: Exposure to violence and other forms of potentially traumatic events (PTEs) are common among youths with externalizing psychopathology. These associations likely reflect both heightened risk for the onset of externalizing problems in youth exposed to PTEs and elevated risk for experiencing PTEs among youth with externalizing disorders. In this study, we disaggregate the associations between exposure to PTEs and externalizing disorder onset in a population-representative sample of adolescents...
September 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28835820/the-coexistence-of-psychiatric-and-gastrointestinal-problems-in-children-with-restrictive-eating-in-a-nationwide-swedish-twin-study
#7
Jakob Täljemark, Maria Råstam, Paul Lichtenstein, Henrik Anckarsäter, Nóra Kerekes
BACKGROUND: Restrictive eating problems are rare in children but overrepresented in those with neurodevelopmental problems. Comorbidities decrease wellbeing in affected individuals but research in the area is relatively scarce. This study describes phenotypes, regarding psychiatric and gastrointestinal comorbidities, in children with restrictive eating problems. METHODS: A parental telephone interview was conducted in 9- or 12-year old twins (n = 19,130) in the Child and Adolescent Twin Study in Sweden...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28832748/prevalence-clinical-correlates-and-maternal-psychopathology-of-deliberate-self-harm-in-children-and-early-adolescents-results-from-a-large-community-study
#8
André R Simioni, Pedro M Pan, Ary Gadelha, Gisele G Manfro, Jair J Mari, Eurípedes C Miguel, Luis A Rohde, Giovanni A Salum
Objectives: Little is known about the prevalence and correlates of deliberate self-harm (DSH) in children from low- and middle-income countries. We investigated the prevalence of DSH and its clinical and maternal psychopathological associations in Brazilian children (n=2,508, ages 6-14y) in a community-based study. Methods: Participants of the High Risk Cohort Study for the Development of Childhood Psychiatric Disorders (HRC) and their mothers were assessed in structured interviews...
August 21, 2017: Revista Brasileira de Psiquiatria
https://www.readbyqxmd.com/read/28816508/stability-and-predictive-validity-of-the-parent-child-sleep-interactions-scale-a-longitudinal-study-among-preschoolers
#9
Chelsey S Barrios, Samantha Y Jay, Victoria C Smith, Candice A Alfano, Lea R Dougherty
Little research has examined the processes underlying children's persistent sleep problems and links with later psychopathology. The current study examined the stability of parent-child sleep interactions as assessed with the parent-reported Parent-Child Sleep Interactions Scale (PSIS) and examined whether sleep interactions in preschool-age children predict sleep problems and psychiatric symptoms later in childhood. Participants included 108 preschool-age children (50% female) and their parents. Parents completed the PSIS when children were 3-5 years (T1) and again when they were 6-9 years (T2)...
August 17, 2017: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/28809509/tailoring-parent-child-interaction-therapy-pcit-for-older-children-a-case-study
#10
Wolfgang Briegel
Parent-Child Interaction Therapy (PCIT) is an evidence-based intervention designed for families of 2- to 6-year-old children with disruptive behavior disorders. This article illustrates the application of PCIT in a 10-year-old boy with attention deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD). Both parents and the patient attended PCIT sessions. The course of therapy included minor changes to the PCIT protocol. After 13 PCIT sessions, the patient displayed disruptive behaviors within normal limits, and 12 months later he no longer met diagnostic criteria for ODD...
August 15, 2017: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
https://www.readbyqxmd.com/read/28808832/factor-structure-of-teacher-ratings-of-the-odd-symptoms-in-children
#11
Rapson Gomez, Vasileios Stavropoulos, George Van Doorn
This study used confirmatory factor analysis (CFA) to determine the best model for Oppositional Defiant Disorder (ODD) symptoms in children aged 3 to 15 years, as presented in the Disruptive Behavior Rating Scale. Teachers' ratings of the ODD symptoms of 213 children from general community schools in Australia were obtained. The findings provided most support for a bifactor model based on Stringaris and Goodman's [1] three-factor model (primary factors for irritable, hurtful, and headstrong). The general factor, but not the group factors in the model, showed high omega hierarchical and explained common variance...
August 15, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28806385/a-naturalistic-comparison-of-methylphenidate-and-risperidone-monotherapy-in-drug-naive-youth-with-attention-deficit-hyperactivity-disorder-comorbid-with-oppositional-defiant-disorder-and-aggression
#12
Gabriele Masi, Azzurra Manfredi, Giulia Nieri, Pietro Muratori, Chiara Pfanner, Annarita Milone
BACKGROUND/PURPOSE: Attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are frequently co-occurring in youth, but data about the pharmacological management of this comorbidity are scarce, especially when impulsive aggression is prominent. Although stimulants are the first-line medication for ADHD, second-generation antipsychotics, namely, risperidone, are frequently used. We aimed to assess effectiveness and safety of monotherapy with the stimulant methylphenidate (MPH) and risperidone in a consecutive sample of 40 drug-naive male youths diagnosed as having ADHD-combined presentation, comorbid with ODD and aggression, without psychiatric comorbidities, according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition criteria and a structured clinical interview (Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version)...
August 10, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28800444/do-parental-adhd-symptoms-reduce-the-efficacy-of-parent-training-for-preschool-adhd-a-secondary-analysis-of-a-randomized-controlled-trial
#13
Rex Forehand, Justin Parent, Virginia D Peisch, Edmund Sonuga-Barke, Nicholas Long, Nicole Lafko Breslend, Howard B Abikoff
Previous studies have suggested that children with Attention-Deficit/Hyperactivity Disorder (ADHD) may benefit less from behavioral parent training (BPT) if their parents have high levels of ADHD symptoms. We conducted a secondary analysis of data from a randomized controlled trial to test the hypothesis that parental ADHD symptoms reduce the efficacy of two BPT programs in a sample of preschoolers with ADHD. One intervention was specifically designed for children with ADHD (NFPP: New Forest Parenting Programme) and one was designed for children with Oppositional Defiant Disorder (ODD) (HNC: Helping the Noncompliant Child)...
October 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/28776147/looming-threats-and-animacy-reduced-responsiveness-in-youth-with-disrupted-behavior-disorders
#14
Stuart F White, Laura C Thornton, Joseph Leshin, Roberta Clanton, Stephen Sinclair, Dionne Coker-Appiah, Harma Meffert, Soonjo Hwang, James R Blair
Theoretical models have implicated amygdala dysfunction in the development of Disruptive Behavior Disorders (DBDs; Conduct Disorder/Oppositional Defiant Disorder). Amygdala dysfunction impacts valence evaluation/response selection and emotion attention in youth with DBDs, particularly in those with elevated callous-unemotional (CU) traits. However, amygdala responsiveness during social cognition and the responsiveness of the acute threat circuitry (amygdala/periaqueductal gray) in youth with DBDs have been less well-examined, particularly with reference to CU traits...
August 3, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28755013/boys-with-oppositional-defiant-disorder-conduct-disorder-show-impaired-adaptation-during-stress-an-executive-functioning-study
#15
Jantiene Schoorl, Sophie van Rijn, Minet de Wied, Stephanie van Goozen, Hanna Swaab
Evidence for problems in executive functioning (EF) in children with oppositional defiant disorder/conduct disorder (ODD/CD) is mixed and the impact stress may have on EF is understudied. Working memory, sustained attention, inhibition and cognitive flexibility of boys with ODD/CD (n = 65) and non-clinical controls (n = 32) were examined under typical and stressful test conditions. Boys with ODD/CD showed impaired working memory under typical testing conditions, and impairments in working memory and sustained attention under stressful conditions...
July 28, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28735697/disentangling-heterogeneity-of-childhood-disruptive-behavior-problems-into-dimensions-and-subgroups
#16
Koen Bolhuis, Gitta H Lubke, Jan van der Ende, Meike Bartels, Catharina E M van Beijsterveldt, Paul Lichtenstein, Henrik Larsson, Vincent W V Jaddoe, Steven A Kushner, Frank C Verhulst, Dorret I Boomsma, Henning Tiemeier
OBJECTIVE: Irritable and oppositional behaviors are increasingly considered as distinct dimensions of oppositional defiant disorder. However, few studies have explored this multidimensionality across the broader spectrum of disruptive behavior problems (DBPs). This study examined the presence of dimensions and distinct subgroups of childhood DBPs, and the cross-sectional and longitudinal associations between these dimensions. METHOD: Using factor mixture models (FMMs), the presence of dimensions and subgroups of DBPs was assessed in the Generation R Study at ages 6 (n = 6,209) and 10 (n = 4,724) years...
August 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28730860/prevalence-of-attention-deficit-hyperactivity-and-other-disruptive-behaviour-disorder-symptoms-among-primary-school-age-children-in-kayseri-turkey
#17
Vesile Senol, Demet Unalan, Raziye Peksen Akca, Mustafa Basturk
Objectives This study aimed to determine the prevalence of attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), and conduct disorder (CD), and their influencing factors on primary school-age children. Methods This cross-sectional study was conducted among 2045 students, 7-15 years old, who were randomly selected from seven schools in Kayseri, Turkey, in 2012. Participants were stratified by socioeconomic status. Data were collected using the Turgay DSM-IV-Based Child and Adolescent Behavioural Disorders Screening and Rating Scale (T-DSM-IV-S)...
January 1, 2017: Journal of International Medical Research
https://www.readbyqxmd.com/read/28728796/-lifetime-psychiatric-disorders-a-comparision-study-between-offspring-of-parents-with-bipolar-disorder-type-i-versus-the-offspring-of-community-controls-parents
#18
Juan David Palacio-Ortiz, Cristian Esteban Peña-Quintero, María Alejandra Gómez-Valero, Paula Andrea Bustamante-Gómez, Pilar Helena Arroyave-Sierra, Cristian David Vargas-Upeguí, Carlos López-Jaramillo
INTRODUCTION: Literature reports show that Bipolar Offspring (BO) present with a wide range of psychiatric disorders. Comparison between BO and Control Parent Offspring (CPO) may help to identify which psychopathological findings are specific to this high-risk group. OBJECTIVE: To compare the psychopathological characteristics between a group of BO type-I and a group of CPO, by identifying the presence of psychiatric disorders according the DSM-IV-TR. METHODS: A descriptive-correlational, cross-sectional and comparative study was conducted with 127 offspring of parents with bipolar disorder type-I from the multimodal intervention program (PRISMA) and with 150 CPO between 6 and 30 years of age...
July 2017: Revista Colombiana de Psiquiatría
https://www.readbyqxmd.com/read/28715786/background-lead-and-mercury-exposures-psychological-and-behavioral-problems-in-children
#19
Brooks B Gump, Matthew J Dykas, James A MacKenzie, Amy K Dumas, Bryce Hruska, Craig K Ewart, Patrick J Parsons, Christopher D Palmer, Kestutis Bendinskas
BACKGROUND: The potential harm from exposure to nonessential metals, particularly mercury (Hg) and lead (Pb), has been the focus of research for years. Initial interest focused on relatively high exposures; however, recent evidence suggests that even background exposures might have adverse consequences for child development. Identifying the extent of these consequences is now a priority. METHODS: We assessed blood Pb and Hg levels in a biracial sample of 9-11 year-old children (N = 203)...
October 2017: Environmental Research
https://www.readbyqxmd.com/read/28713321/multi-level-family-factors-and-affective-and-behavioral-symptoms-of-oppositional-defiant-disorder-in-chinese-children
#20
Yixin Tang, Xiuyun Lin, Peilian Chi, Qing Zhou, Xiangning Hou
Given the important role of family environment in children's psychological development, the objective of this study was to examine the linkages between family factors at the whole, dyadic, and individual levels and two dimensions (affective and behavioral) of Oppositional Defiant Disorder (ODD) symptoms in Chinese children. Participants comprised of 80 father-child dyads and 169 mother-child dyads from families with ODD children. The results indicated that multilevel family factors were differently associated with children's affective and behavioral ODD symptoms...
2017: Frontiers in Psychology
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