ASV device

Most microorganisms found in environmental samples have never been cultured and can often only be explored through molecular or microscopic approaches. Here, we adapt the use of in situ diffusion-based devices to culture "yet-to-be-cultured" microorganisms associated with coral mucus and compare this with a traditional culturing method. The culturability of microorganisms associated with mucus of the coral Pocillopora damicornis increased by 420% and 570% with diffusion growth chambers and microwell chip devices, respectively, compared with the traditional method tested...

BACKGROUND: In patients with heart failure and reduced ejection fraction, sleep-disordered breathing, comprising obstructive sleep apnoea (OSA) and central sleep apnoea (CSA), is associated with increased morbidity, mortality, and sleep disruption. We hypothesised that treating sleep-disordered breathing with a peak-flow triggered adaptive servo-ventilation (ASV) device would improve cardiovascular outcomes in patients with heart failure and reduced ejection fraction. METHODS: We conducted a multicentre, multinational, parallel-group, open-label, phase 3 randomised controlled trial of peak-flow triggered ASV in patients aged 18 years or older with heart failure and reduced ejection fraction (left ventricular ejection fraction ≤45%) who were stabilised on optimal medical therapy with co-existing sleep-disordered breathing (apnoea-hypopnoea index [AHI] ≥15 events/h of sleep), with concealed allocation and blinded outcome assessments...

BACKGROUND: The sleep medicine community has struggled to identify the ideal role for adaptive servo-ventilation (ASV) therapy following a study that found increased mortality in patients with central sleep apnea (CSA) and heart failure with reduced ejection fraction who used ASV therapy. We aimed to identify characteristics of patients who benefit from ASV therapy. METHODS: We performed a record review of all patients treated with ASV therapy at the Hampton Veterans Affairs Medical Center in Virginia from January 1, 2015, to April 30, 2020...

Maritime obstacle detection is critical for safe navigation of autonomous surface vehicles (ASVs). While the accuracy of image-based detection methods has advanced substantially, their computational and memory requirements prohibit deployment on embedded devices. In this paper, we analyze the current best-performing maritime obstacle detection network, WaSR. Based on the analysis, we then propose replacements for the most computationally intensive stages and propose its embedded-compute-ready variant, eWaSR...

A sensitive electrochemical device was suggested via the modification of a simple graphite rod electrode (GRE) with cobalt hydroxide (Co(OH)2 ) nanosheets. After closed circuit process on the modified electrode, the anodic stripping voltammetry (ASV) technique was used for measuring of Hg(II). In optimal experimental conditions, the suggested assay depicted a linear response over a broad range in the range 0.25-30 μg L-1 , with the lowest detection limit of 0.07 μg L-1 ...

Servo-ventilation (SV) was developed for treating central sleep apnea (CSA). SV devices manufactured by Philips Respironics and ResMed are primarily used to date. However, the difference in reaction to sleep-disordered breathing (SDB) events between bilevel positive airway pressure (BPAP) AutoSV devices for Philips and ASV devices for ResMed in clinical settings is unknown. Herein, we describe a case of CSA with SDB events successfully controlled and sleepiness, sleep quality, and tolerance of device improved by changing the BPAP AutoSV device for Philips to the ASV device for ResMed...

BACKGROUND: Continuous surveillance helps people with diabetes live better lives. A wide range of technologies, including the Internet of Things (IoT), modern communications, and artificial intelligence (AI), can assist in lowering the expense of health services. Due to numerous communication systems, it is now possible to provide customized and distant healthcare. MAIN PROBLEM: Healthcare data grows daily, making storage and processing challenging. We provide intelligent healthcare structures for smart e-health apps to solve the aforesaid problem...

BACKGROUND: Central sleep apnea (CSA) is associated with increased mortality and morbidity in patients with heart failure with reduced ejection fraction (HFrEF). Treatment of CSA with a certain type of adaptive servo-ventilation (ASV) device that targets minute ventilation (ASVmv) was found to be harmful in these patients. A newer generation of ASV devices that target peak flow (ASVpf) is presumed to have different effects on ventilation and airway patency. We analyzed our registry of patients with HFrEF-CSA to examine the effect of exposure to ASV and role of each type of ASV device on mortality...

Cardiac decompensation is associated with worse prognosis in patients with heart failure. Reliable methods to predict cardiac decompensation events are not yet available. Sleep-disordered breathing (SDB) is a frequent comorbidity in heart failure, and it has been shown to correlate with heart failure severity. This prospective observational trial investigated SDB characteristics in patients with heart failure with the aim to identify patterns that may predict early cardiac decompensation. Patients with heart failure with diagnosed SDB and hospitalised for cardiac decompensation were prospectively enrolled and treated with adaptive servo-ventilation (ASV)...

UNLABELLED: The aim of this work was to determine whether therapy with adaptive support ventilation (ASV) leads to impairment of acid-base balance, in particular to hypocapnia and alkalosis. For this purpose, we measured the acid-base status (SBH) with carbon dioxide and oxygen partial pressure in arterialized blood (pCO2 and pO2 ), standard bicarbonate (SBC) and pH under spontaneous breathing during the day and under ASV at night. The trigger for this work was, among other things, the result of the SERVE-HF study, which found an increased risk of mortality in patients with heart failure and left ventricular ejection fraction <45% under ASV...

Water quality monitoring has become more critical in recent years to ensure the availability of clean and safe water from natural aquifers and to understand the evolution of water contaminants across time and space. The conventional water monitoring techniques comprise of sample collection, preservation, preparation, tailed by laboratory testing and analysis with cumbersome wet chemical routes and expensive instrumentation. Despite the high accuracy of these methods, the high testing costs, laborious procedures, and maintenance associated with them don't make them lucrative for end end-users and field testing...

It is known that patients with heart failure (HF) have an increased risk of developing central sleep apnoea (CSA), with Cheyne-Stokes respiration. The development of servo-ventilation aimed to treat CSA and improve the quality of life (QoL) of these patients. A large randomized clinical study, SERVE-HF, was conducted in order to test this theory in patients with HF and reduced ejection fraction (HFrEF). The results from this trial seemed to indicate that, in these patients, there was no beneficial effect of the assisted ventilation in CSA treatment...

Up until now, bovine fetometry has been entirely based on 2-dimensional ultrasonography. Fetal size is estimated by several linear measurements such as crown-rump length (CRL). However, the advent of 3-dimensional ultrasonography (3D-US) provides in vivo access to the volumes of the fetus and its amniotic sac. The objective of this preliminary observational study was to determine the variability of conceptus-related volumes using transrectal 3D-US in dairy cows and to identify factors affecting them. Furthermore, relationships between the gained measurements and calf birth weight were investigated...

Background: Clinical outcomes of adaptive servo-ventilation (ASV) therapy have not been rigorously assessed. Optimal device settings ascertained by a pressure ramp test may increase the utility of ASV therapy. Methods and Results: Patients with congestive heart failure (CHF) who underwent ASV therapy were prospectively included in the study. Patients in the ramp test group underwent a pressure ramp test, during which the end-expiratory pressure was optimized to maximize cardiac output (assessed using the AESCLONE mini)...

In this paper, a vibrating boron-doped diamond (BDD) electrode electroanalytical device and respective method for the analysis of ultralow concentrations of Cd(II) in water were studied. The enhanced mass transfer on the electrode surface was studied using Ru(NH3 )6 Cl3 . Vibration with 133 Hz frequency enhanced the Ru(III) to Ru(II) reduction by 92.6% compared to a static electrode. The peak current of the anodic stripping voltammetry (ASV) method employed was increased by a factor of 5.3 and 4.7 for 10 and 30 μg L-1  Cd(II) concentrations, respectively, when a frequency of 200 Hz was used...

This document summarizes suggestions of the central sleep apnea (CSA) Technical Expert Panel working group. This paper shares our vision for bringing the right device to the right patient at the right time. For patients with CSA, current coverage criteria do not align with guideline treatment recommendations. For example, CPAP and oxygen therapy are recommended but not covered for CSA. On the other hand, bilevel positive airway pressure (BPAP) without a backup rate may be a covered therapy for OSA, but it may worsen CSA...

Introduction: Adaptive servo-ventilation (ASV) devices are designed to suppress central respiratory events, and therefore effective for sleep-disordered breathing (SDB) in patients with heart failure (HF) and provide information about their residual respiratory events. However, whether the apnea-hypopnea index (AHI), determined by the ASV device AutoSet CS (ASC), correlates with the AHI calculated by polysomnography (PSG) in patients with HF and SDB remains to be evaluated. Methods: Consecutive patients with SDB titrated on ASC were included in the study...

STUDY OBJECTIVES: There is minimal guidance around how to optimize inspiratory positive airway pressure (IPAP) levels during use of adaptive servo ventilation (ASV) in clinical practice. This real-world data analysis investigated the effects of IPAP and minimum pressure support settings on respiratory parameters and adherence in ASV-treated patients. METHODS: A United States-based telemonitoring database was queried for patients starting ASV between August 1, 2014 and November 30, 2019...

Different cyclodextrin-calixarene nanosponges (CyCaNSs) have been characterized by means of FFC-NMR relaxometry, and used as sorbents to remove Pb2+ ions from aqueous solutions. Considering that the removal treatments may involve polluted waters with different characteristics, the adsorption experiments were performed on solutions without and with the addition of background salts, under different operational conditions. The adsorption abilities and affinities of the nanosponges towards Pb2+ ions were investigated by measuring the metal ion concentration by means of Inductively Coupled Plasma Emission Spectroscopy (ICP-OES) and Differential Pulse Anodic Stripping Voltammetry (DP-ASV)...

In this paper, a 3D-printed microfluidic device is described which is suitable for sequential injection/anodic stripping voltammetric (SIA-ASV) determination of Pb(II) and Cd(II). The fluidic device is manufactured by 3D-printing in a single-step using a dual extruder 3D printer. The device is composed of a microfluidic cell (printed from a non-conductive polylactic acid (PLA) filament) and of 3 electrodes (printed from a conductive carbon-loaded PLA filament) which are integrated within the fluidic cell. During the preconcentration step, a zone of the sample (containing the target cations) and a zone of Bi(III) solution are mixed on-line and the cations are reduced on the working electrode forming a bismuth alloy...