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https://www.readbyqxmd.com/read/28524151/-etiopathogenesis-of-ocular-ischemic-syndrome
#1
D К Makhkamova
Ocular ischemic syndrome (OIS) is a collection of symptoms of carotid and ophthalmic artery disease of common genesis accompanied by ischemia of eyeball membranes. Specifically, the intraocular blood flow becomes impaired due to inflow reduction or arrest, while the venous outflow remains patent. Causes of OIS include arterial hypertension, atherosclerosis, diabetes, aortoarteritis and other vascular diseases. Clinical features depend on the extent, nature, and site of vascular involvement as well as the concurrent pathology...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28515345/genetic-factors-associated-with-risk-of-metabolic-syndrome-and-hepatocellular-carcinoma
#2
REVIEW
Ranran Tang, Heng Liu, Yingdi Yuan, Kaipeng Xie, Pengfei Xu, Xiaoyun Liu, Juan Wen
Although the metabolic syndrome is a commonplace topic, its potential threats to public health is a problem that cannot be neglected. As the living conditions improved significantly over the past few years, the morbidity of metabolic syndrome has also steadily risen, and the onset age is becoming younger. The hepatocellular carcinoma (HCC), is one of the most prevalent life-threatening human cancers worldwide, incidence of which is also on the rise, gradually occupied the top of the list associated with metabolic syndrome related complication...
May 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28513399/reducing-health-inequalities-for-people-with-serious-mental-illness
#3
Nutmeg Hallett, Helen Rees
People with serious mental illness (SMI) are at risk of dying many years earlier than the general population. Providing an effective, cost-efficient healthcare service requires a holistic approach, and improving the physical health of people with SMI should be integral to all healthcare roles. It is important for nurses to identify and understand the barriers that people with SMI may experience when accessing physical healthcare. A range of factors contribute to reduced life expectancy, including lifestyle factors, symptoms of mental illness and the side effects of medications...
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28511823/dissociation-and-conversion-symptoms-in-dermatology
#4
Madhulika A Gupta, Branka Vujcic, Aditya K Gupta
Dissociation and conversion (defined as the somatic component of dissociation) can play an important mediating role in the exacerbation of the stress-reactive dermatoses (eg, psoriasis, idiopathic urticaria, atopic dermatitis), dermatoses that are exacerbated by excessive scratching (eg, lichen simplex chronicus, prurigo nodularis) and koebnerization, and the self-induced dermatoses (dermatitis artefacta, acne excoriée, skin picking disorder, trichotillomania, onychotillomania/onychophagia). Dissociative symptoms often coexist with obsessive-compulsive symptoms in the more severe cases of the self-induced dermatoses...
May 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28488108/-ventricular-tachyarrhythmia-as-a-side-effect-of-pharmacotherapy
#5
REVIEW
Thomas Demming, Hendrik Bonnemeier
Ventricular tachyarrhythmia is a severe and life-threatening potential side effect of pharmacotherapy. Substances with proarrhythmic potential belong to various groups of medication. Apart from antiarrhythmic agents, especially antibiotics and psychiatric drugs are worth mentioning owing to their broad application. Interaction with cardiac potassium channels is the most important reason for drug-induced ventricular tachyarrhythmia. Over 20 years of research in animal models and clinical studies have uncovered the underlying mechanisms...
May 9, 2017: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/28473804/the-complement-system-a-prey-of-trypanosoma-cruzi
#6
REVIEW
Kárita C F Lidani, Lorena Bavia, Altair R Ambrosio, Iara J de Messias-Reason
Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a neglected sickness that affects around 6-8 million people worldwide. Originally, CD was mainly found in Latin America but more recently, it has been spread to countries in North America, Asia, and Europe due the international migration from endemic areas. Thus, at present CD represents an important concern of global public health. Most of individuals that are infected by T. cruzi may remain in asymptomatic form all lifelong, but up to 40% of them will develop cardiomyopathy, digestive mega syndromes, or both...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28464773/the-role-of-atypical-antipsychotics-in-sexuality-road-to-recovery-in-schizophrenia
#7
Raja Lope Adam, Hatta Sidi, Marhani Midin, Hazli Zakaria, Srijit Das, Khairi Che Mat
Sexuality is an important dimension in human beings as a form of expression of individuality. For many decades, sexual functioning has been a neglected area among patients suffering from schizophrenia. It was a presumption that patients with schizophrenia could be asexual and this could be secondary to overwhelming situations of delusion, hallucination, hostility and negative symptoms among others. The deficient in sexual functioning are due to innate factors, i.e. negative symptoms (apathy, avolition and amotivation) and also as a result of prefrontal dysfunction, i...
May 2, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28455127/oxidative-stress-in-mayaro-virus-infection
#8
Fernanda Caetano Camini, Camila Carla da Silva Caetano, Letícia Trindade Almeida, Joyce Ferreira da Costa Guerra, Breno de Mello Silva, Silvana de Queiroz Silva, José Carlos de Magalhães, Cintia Lopes de Brito Magalhães
Mayaro virus (MAYV) is a neglected tropical arbovirus that causes a febrile syndrome that is sometimes accompanied by incapacitating arthritis/arthralgia. The pathogenesis of MAYV has not been completely defined and oxidative stress mediated by an increase in reactive oxygen species (ROS) and/or depletion of antioxidant defences has been found to contribute to several aspects of viral disease. To investigate whether MAYV induced oxidative stress in host cells, we monitored ROS production, oxidative stress markers and antioxidant defences at different time points after infection...
April 25, 2017: Virus Research
https://www.readbyqxmd.com/read/28449491/characteristics-and-provision-of-care-of-patients-with-the-acute-respiratory-distress-syndrome-descriptive-findings-from-the-dacapo-cohort-baseline-and-comparison-with-international-findings
#9
Frank Dodoo-Schittko, Susanne Brandstetter, Magdalena Brandl, Sebastian Blecha, Michael Quintel, Steffen Weber-Carstens, Stefan Kluge, Patrick Meybohm, Caroline Rolfes, Björn Ellger, Friedhelm Bach, Tobias Welte, Thomas Muders, Kathrin Thomann-Hackner, Thomas Bein, Christian Apfelbacher
BACKGROUND: Little is known about the characteristics and real world life circumstances of ARDS (acute respiratory distress syndrome) patient populations. This knowledge is essential for transferring evidence-based therapy into routine healthcare. The aim of this study was to report socio-demographic and clinical characteristics in an unselected population of ARDS patients and to compare these results to findings from other large ARDS cohorts. METHODS: A German based cross-sectional observational study was carried out...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28444704/how-does-lower-urinary-tract-dysfunction-lutd-affect-sexual-function-in-men-and-women-ici-rs-2015-part-2
#10
REVIEW
Apostolos Apostolidis, Angie Rantell, Ralf Anding, Ruth Kirschner-Hermanns, Linda Cardozo
AIM: To discuss available data on the links between LUTD and sexual dysfunction, what is still unknown about the causative effect of disease processes on sexual function (SF), and to suggest proposals for further research. METHODS: At the 2015 International Consultation on Incontinence-Research Society (ICI-RS), a multi-disciplinary group presented a literature search of what is known about the effect of LUTD on SF in men and women. Wider discussions regarding knowledge gaps, and ideal research methodology ensued and are presented...
April 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28436100/global-and-regional-trends-in-the-nutritional-status-of-young-people-a-critical-and-neglected-age-group
#11
REVIEW
Nadia Akseer, Sara Al-Gashm, Seema Mehta, Ali Mokdad, Zulfiqar A Bhutta
Adolescence and emerging adulthood form a critical time period for the achievement of optimal health and nutrition across all stages of the life course. We undertook a review of published literature and global data repositories for information on nutrition levels, trends, and patterns among young people aged 10-24 years from January 1, 2016 to September 20, 2016. We describe patterns for both males and females at the global level and for geographic regions for the period covering 1990-2015. The results of this study paint a less than ideal picture of current young people's nutrition, suggesting dual burdens of underweight and high body-mass index in many countries and variable improvements in micronutrient deficiencies across geographical regions...
April 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28429801/the-dizzy-patient-don-t-forget-disorders-of-the-central-vestibular-system
#12
REVIEW
Thomas Brandt, Marianne Dieterich
Vertigo and dizziness are among the most common complaints in neurology clinics, and they account for about 13% of the patients entering emergency units. In this Review, we focus on central vestibular disorders, which are mostly attributable to acute unilateral lesions of the bilateral vestibular circuitry in the brain. In a tertiary interdisciplinary outpatient dizziness unit, central vestibular disorders, including vestibular migraine, comprise about 25% of the established diagnoses. The signs and symptoms of these disorders can mimic those of peripheral vestibular disorders with sustained rotational vertigo...
April 21, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28387593/a-case-of-posterior-cortical-atrophy-with-vertical-neglect
#13
Hilary Glazer, Leila Saadatpour, Leilani Doty, Kenneth M Heilman
Posterior cortical atrophy (PCA) is a syndrome caused by a neurodegenerative disease that often presents with visuospatial deficits, and can be debilitating. PCA is often characterized by elements of Balint's syndrome and dyslexia. The most common underlying pathology has been found to be Alzheimer's disease. Signs of horizontal neglect are frequently associated with PCA, but the presence of vertical (or altitudinal) neglect has not yet been reported in a patient with PCA or other forms of neurodegenerative dementia...
April 7, 2017: Neurocase
https://www.readbyqxmd.com/read/28374655/childhood-maltreatment-in-children-born-of-occupation-after-wwii-in-germany-and-its-association-with-mental-disorders
#14
Heide Glaesmer, Philipp Kuwert, Elmar Braehler, Marie Kaiser
BACKGROUND: Children born of war are a common phenomenon of conflict. In the aftermath of World War II, more than 200,000 German occupation children (GOC) were fathered by occupation soldiers and born to local women. GOC often grew up under difficult conditions and showed high prevalence rates of mental disorders even decades later. METHODS: Experiences of childhood maltreatment and their association with Posttraumatic Stress Disorder (PTSD), depression, and somatization in GOC (N = 146) are investigated and compared with a representative birth-cohort-matched sample (BCMS) from the German general population (N = 920)...
April 4, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28371620/the-effect-of-sexual-abuse-and-prenatal-substance-use-on-successful-breastfeeding
#15
Lauren M Jansson, Martha L Velez, Arlene M Butz
Barriers to breastfeeding in women with substance use disorders (SUDs) often exist. Neonatal abstinence syndrome-related feeding difficulties, maternal SUD-related maladaptive behaviors, and psychological comorbidities can adversely affect breastfeeding. A neglected barrier that frequently occurs in women with SUDs is a history of sexual abuse. It is important that nurses and providers understand each maternal and/or infant factor that can affect the breastfeeding course to assist effectively with lactation support for these frequently misunderstood dyads...
May 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28361069/posterior-reversible-encephalopathy-syndrome-associated-with-left-horizontal-gaze-palsy
#16
Amer Hawatmeh, Sarah Studyvin, Moh'd Al-Halawani, Sawsan Amireh, Mohammad Thawabi
Posterior reversible encephalopathy syndrome (PRES) is characterized by rapid onset of symptoms including headache, seizures, altered consciousness, and visual disturbance, as well as radiologic findings of focal reversible vasogenic edema. Multiple visual disturbances have been described in PRES, such as hemianopia, visual neglect, auras, visual hallucinations, and cortical blindness. However, horizontal gaze palsy has not been previously reported. We report a 72-year-old female who presented with blurred vision, severe headache, lethargy, and later developed seizures...
March 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28348160/zika-virus-a-race-in-search-for-antivirals
#17
Juan-Carlos Saiz, Miguel A Martín-Acebes
Zika virus (ZIKV), a flavivirus transmitted by mosquitoes, was an almost neglected pathogen until its introduction in the Americas in 2015, and its subsequent explosive spread throughout the continent, where it has infected millions of people. The virus has caused social and sanitary alarm, mainly due to its association with severe neurological disorders (Guillain-Barré syndrome, and microcephaly in fetus and newborns). Nowadays, no specific antiviral therapy is available against ZIKV. However, during the past months, a great effort has been made in search for antiviral candidates by using different approaches and methodologies, from testing specific compounds with known antiviral activity to screenings of libraries with hundreds of bioactive molecules...
March 27, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28316098/therapeutic-options-for-dysfunctional-breathing-in-children-and-adolescents
#18
Bodo Niggemann, Christine Lehmann, Dorothea Pfeiffer-Kascha, Christa Weiss
No abstract text is available yet for this article.
March 17, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28314918/oculomotor-prismatic-training-is-effective-in-ameliorating-spatial-neglect-a-pilot-study
#19
I Ronga, M Franza, P Sarasso, M Neppi-Modona
Visuomotor prismatic training has been demonstrated to be among the most effective rehabilitative techniques of spatial neglect, a neurological syndrome manifested by a number of right brain-damaged patients characterized by unawareness of the egocentric left half of the world. In the present study, we demonstrate that a novel oculomotor prismatic training procedure only consisting in a sequence of gaze shifts to visual targets, can reduce spatial neglect symptoms. Following oculomotor prismatic training, patients show a significant decrease in neglect severity in straight ahead and paper and pencil tasks...
March 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28289763/-gender-and-cardiovascular-diseases-why-we-need-gender-medicine
#20
V Regitz-Zagrosek
Gender medicine is concerned with the question of why diseases are expressed differently in the genders. It takes differences between men and women into account, which are often neglected by traditional medicine. Sex differences can also be found in cardiovascular diseases; therefore, risk factors for cardiovascular diseases have a different significance depending on the sex. Diabetic diseases tend to promote the occurrence of coronary heart disease (CHD) more strongly in women than in men. Myocardial infarctions affect women 10 years later than men and young women are often treated too late, possibly because myocardial infarction is consider to be a "male disease"...
March 13, 2017: Der Internist
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