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Neglect syndrome

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https://www.readbyqxmd.com/read/29031739/neural-correlates-of-visuospatial-bias-in-patients-with-left-hemisphere-stroke-a-causal-functional-contribution-analysis-based-on-game-theory
#1
C Malherbe, R Umarova, M Zavaglia, C Kaller, L Beume, G Thomalla, C Weiller, C C Hilgetag
Stroke patients frequently display spatial neglect, an inability to report, or respond to, relevant stimuli in the contralesional space. Although this syndrome is widely considered to result from the dysfunction of a large-scale attention network, the individual contributions of damaged grey and white matter regions to neglect are still being disputed. Moreover, while the neuroanatomy of neglect in right hemispheric lesions is well studied, the contributions of left hemispheric brain regions to visuospatial processing are less well understood...
October 11, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28980607/-metavestibular-disorders-and-disorders-of-higher-vestibular-function
#2
M V Zamergrad, O S Levin
Vertigo, instability, oscillopsia and concomitant autonomic disorders are classical and well-known symptoms of vestibular disorders. At the same time, recent studies suggest that there are more complicated vestibular dysfunctions caused by the cortical projections of the vestibular system. The central vestibular system includes parietal temporal cortex and insular, anterior intraparietal sulcus, posterior parietal and medial parts of the superior temporal gyrus, singular gyrus retrosplenial cortex, hippocampus and parahippocampal area...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28980076/the-assessment-of-hemineglect-syndrome-with-cancellation-tasks-a-comparison-between-the-bells-test-and-the-apples-test
#3
Benedetta Basagni, Antonio De Tanti, Alessio Damora, Laura Abbruzzese, Valentina Varalta, Gabriella Antonucci, Wai Ling Bickerton, Nicola Smania, Mauro Mancuso
Unilateral spatial neglect (USN) is a frequent consequence of acquired brain injury, especially following right hemisphere damage. Traditionally, unilateral spatial neglect is assessed with cancellation tests such as the Bells test. Recently, a new cancellation test, the Apples test, has been proposed. The present study aims at comparing the accuracy of these two tests in detecting hemispatial neglect, on a sample of 56 right hemisphere stroke patients with a diagnosis of USN. In order to evaluate the agreement between the Apples and Bells tests, Cohen's kappa and McNemar's test were used to assess differences between the two methods of evaluation...
October 4, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28976883/is-the-burnout-syndrome-associated-with-elder-mistreatment-in-nursing-homes-results-of-a-cross-sectional-study-among-nurses
#4
Marijana Neuberg, Danica Železnik, Tomislav Meštrović, Rosana Ribić, Goran Kozina
As this issue has not yet been addressed in Croatia, our aim was to explore the presence of the burnout syndrome in nurses and see how it is related to their perception of elder mistreatment in nursing homes and extended care units. The burnout syndrome was assessed in 171 nursing professionals with a standardised Maslach Burnout Inventory for Human Services Survey (MBI-HSS) for three dimensions: emotional exhaustion (EE), depersonalisation (DP), and personal accomplishment (PA). High EE was reported by 43...
September 26, 2017: Arhiv za Higijenu Rada i Toksikologiju
https://www.readbyqxmd.com/read/28960534/factors-associated-with-demoralization-syndrome-in-patients-before-and-after-cardiac-surgery
#5
Hsiu-Yun Liao, Chaw-Chi Chiu, Ying-Ying Ko, Hsing-Mei Chen
AIMS AND OBJECTIVES: This paper sought to investigate the incidence of and contributors to demoralization syndrome among patients before and after cardiac surgery. BACKGROUND: Demoralization syndrome is a common but neglected phenomenon in nursing practice. Patients who require cardiac surgery experience demoralization syndrome more often than they experience depression. DESIGN: A prospective correlational design was applied. METHODS: A convenience sample of 76 participants undergoing cardiac surgery was recruited from the cardiovascular wards of two medical centres in Taiwan...
September 27, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28953089/lawsuits-after-primary-and-revision-total-knee-arthroplasty-a-malpractice-claims-analysis
#6
Diana C Patterson, Ronald Grelsamer, Michael J Bronson, Calin S Moucha
INTRODUCTION: As the number of total knee arthroplasties (TKAs) increases, the number of associated complications will also increase. Our goal with this study was to identify common causes of and financial trends relating to malpractice claims filed after TKA. METHODS: We analyzed malpractice claims filed for alleged neglectful primary and revision TKA surgeries performed between 1982 and 2012 by orthopaedic surgeons insured by a large New York state malpractice carrier...
October 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28916298/childhood-trauma-depression-and-sleep-quality-and-their-association-with-psychotic-symptoms-and-suicidality-in-schizophrenia
#7
Esin Evren Kilicaslan, Asli Tugba Esen, Meltem Izci Kasal, Erdal Ozelci, Murat Boysan, Mustafa Gulec
This study involved the examination of the relationship between childhood trauma and both psychotic symptoms and suicidality in patients with schizophrenia after controlling for the possible confounding factors, such as clinical features, depression, and sleep quality. The Childhood Trauma Questionnaire-Short Form, Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), Pittsburgh Sleep Quality Index (PSQI), and the suicidality subscale of Mini-International Neuropsychiatric Interview (MINI) were administered to 199 patients with schizophrenia...
September 7, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28913704/impact-of-etiology-age-and-gender-on-onset-and-severity-of-hyponatremia-in-patients-with-hypopituitarism-retrospective-analysis-in-a-specialised-endocrine-unit
#8
Dragana Miljic, Mirjana Doknic, Marko Stojanovic, Marina Nikolic-Djurovic, Milan Petakov, Vera Popovic, Sandra Pekic
BACKGROUND: Hyponatremia can unmask hypopituitarism and secondary adrenal insufficiency. This is important, since the need to screen for steroid deficiency, in patients with hyponatremia is often neglected. PATIENTS AND METHODS: In a retrospective study, twenty-five patients (13f/12m, age 58.9 ± 18.6 years) with hyponatremia (119.7 ± 10.5 mmol/L) were identified among 260 in-patients treated for hypopituitarism in our specialized endocrine unit, over the last decade...
September 14, 2017: Endocrine
https://www.readbyqxmd.com/read/28892593/much-more-than-prescribing-a-pill-assessment-and-treatment-of-erectile-dysfunction-by-the-general-practitioner
#9
Ohad Shoshany, Darren J Katz, Christopher Love
BACKGROUND: Erectile dysfunction is a common but often neglected condition. Prevalence increases with age, but is not insignificant in younger men. OBJECTIVE: This article will broadly describe the epidemiology, classification and risk factors of erectile dysfunction. It will also discuss assessment and current treatment modalities, with a particular focus on the unique role of the general practitioner (GP). DISCUSSION: Erectile dysfunction may be classified as vasculogenic, neurogenic, endocrinological, drug-related, psychogenic or mixed...
September 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28879824/under-reporting-giardiasis-time-to-consider-the-public-health-implications
#10
S L Currie, N Stephenson, A S Palmer, B L Jones, C L Alexander
Giardiasis is a treatable disease, caused by the flagellated protozoan parasite, Giardia duodenalis (G. duodenalis). It is one of the most common enteric parasites found globally to cause gastrointestinal disturbances, and infections may result in long-term irritable bowel syndrome-like symptoms. It is a common misconception that giardiasis is associated with foreign travel, which results in locally acquired cases in the UK being underdiagnosed. This report highlights the findings from one large Scottish Health Board, arising from a change in testing methodology, which resulted in the screening of all stools submitted for enteric investigations for G...
October 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28844076/synaptic-loss-and-the-pathophysiology-of-ptsd-implications-for-ketamine-as-a-prototype-novel-therapeutic
#11
REVIEW
John H Krystal, Chadi G Abdallah, Lynette A Averill, Benjamin Kelmendi, Ilan Harpaz-Rotem, Gerard Sanacora, Steven M Southwick, Ronald S Duman
PURPOSE OF REVIEW: Studies of the neurobiology and treatment of PTSD have highlighted many aspects of the pathophysiology of this disorder that might be relevant to treatment. The purpose of this review is to highlight the potential clinical importance of an often-neglected consequence of stress models in animals that may be relevant to PTSD: the stress-related loss of synaptic connectivity. RECENT FINDINGS: Here, we will briefly review evidence that PTSD might be a "synaptic disconnection syndrome" and highlight the importance of this perspective for the emerging therapeutic application of ketamine as a potential rapid-acting treatment for this disorder that may work, in part, by restoring synaptic connectivity...
August 26, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28843415/complexity-vs-unity-in-unilateral-spatial-neglect
#12
REVIEW
G Rode, M Fourtassi, C Pagliari, L Pisella, Y Rossetti
Unilateral spatial neglect constitutes a heterogeneous syndrome characterized by two main entangled components: a contralesional bias of spatial attention orientation; and impaired building and/or exploration of mental representations of space. These two components are present in different subtypes of unilateral spatial neglect (visual, auditory, somatosensory, motor, allocentric, egocentric, personal, representational and productive manifestations). Detailed anatomical and clinical analyses of these conditions and their underlying disorders show the complexity of spatial cognitive deficits and the difficulty of proposing just one explanation...
August 23, 2017: Revue Neurologique
https://www.readbyqxmd.com/read/28837209/erythrocyte-heme-proteins-and-stemi-implications-in-prognosis
#13
Judit Cubedo, Rosa Suades, Teresa Padro, Victoria Martin-Yuste, Manel Sabate-Tenas, Juan Cinca, Jordi Sans-Rosello, Alessandro Sionis, Lina Badimon
The role of erythrocytes in thrombus formation has been often neglected, but some studies have highlighted their active role in thrombotic events. Free-haemoglobin (Hb) has shown to induce oxidative-stress damage. Herein we have investigated the coordinated changes in heme-related proteins in patients with acute-coronary-syndromes (ACS), their association to ongoing thrombosis and their impact on patients' prognosis. The serum proteome of STEMI-patients (N=27) within the first 6h after event-onset and 3d after were compared to controls (N=60)...
October 5, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28836540/gingival-fibromatosis-with-hypertrichosis-syndrome-case-series-of-rare-syndrome
#14
Preetha Balaji, S M Balaji
Gingival fibromatosis with hypertrichosis syndrome is an extremely rare genetic condition characterized by profound overgrowth of hair and gums, as well as other variable features. Gingival fibromatosis is characterized by a large increase in the gingival dimension which extends above the dental crowns, covering them partially or completely. They were found to have a genetic origin, may also occur in isolation or be part of a syndrome, or acquired origin, due to specific drugs administered systemically. Congenital generalized hypertrichosis is a heterogeneous group of diseases with continuing excessive growth of terminal hair without androgenic stimulation...
July 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28833355/serum-chemerin-levels-are-inversely-associated-with-renal-function-in-a-general-population
#15
Stephanie Zylla, Rainer Rettig, Henry Völzke, Karlhans Endlich, Matthias Nauck, Nele Friedrich
OBJECTIVE: Chemerin has been found to be highly expressed in the kidneys of rodents and has been suggested to affect metabolic syndrome (MetS)-related phenotypes which are in turn related to kidney damage. Only few clinical studies have addressed the relation between circulating chemerin and renal function in humans, and no population-based analyses have yet been performed. The potential influence of MetS-related phenotypes on the assumed association has been largely neglected. We aimed to investigate the association of serum chemerin with renal function in a general population with special regard to possible interactions between chemerin and metabolic phenotypes...
August 18, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28813816/computational-rehabilitation-of-neglect-using-state-space-models-to-understand-the-recovery-mechanisms
#16
Giulia Sedda, Marcella Ottonello, Elena Fiabane, Caterina Pistarini, Anna Sedda, Vittorio Sanguineti
Unilateral spatial neglect is a neuropsychological syndrome often observed in right hemisphere stroke patients. The symptoms differ from subject to subject. A few rehabilitation approaches, e.g. prism adaptation, have demonstrated some effect in reducing the symptoms, but the underlying mechanisms are still largely unclear. Recently, neural models have been proposed to qualitatively describe cortical lesions, the resulting neglect symptoms and the effects of treatment. However, these predictions are qualitative and cannot be used to compare different hypotheses or to interpret symptoms at individual subjects level...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28806608/differential-effects-of-childhood-trauma-subtypes-on-fatigue-and-physical-functioning-in-chronic-fatigue-syndrome
#17
Maud De Venter, Jela Illegems, Rita Van Royen, Greta Moorkens, Bernard G C Sabbe, Filip Van Den Eede
OBJECTIVE: There is wide consensus that childhood trauma plays an important role in the aetiology of chronic fatigue syndrome (CFS). The current study examines the differential effects of childhood trauma subtypes on fatigue and physical functioning in individuals suffering from CFS. METHODS: Participants were 155 well-documented adult, predominantly female CFS patients receiving treatment at the outpatient treatment centre for CFS of the Antwerp University Hospital in Belgium...
July 19, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28804863/personalised-immunomodulating-treatments-for-graves-disease-fact-or-fiction
#18
Tristan Mirko Struja, Alexander Kutz, Stefan Fischli, Christian Meier, Beat Müller, Philipp Schütz
Although Graves' disease has been recognised for more than 100 years, its physiopathological mechanisms are incompletely understood. Treatment strategies today mainly focus on suppression of thyroid hormone production by use of antithyroid drugs or radio-iodine, but neglect the underlying immunological mechanisms. Although Graves' disease is often seen as a prototype for an autoimmune mechanism, it is more likely to be a heterogeneous syndrome showing characteristics of both autoimmunity and immunodeficiency...
August 14, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28774696/neglected-endemic-mycoses
#19
REVIEW
Flavio Queiroz-Telles, Ahmed Hassan Fahal, Diego R Falci, Diego H Caceres, Tom Chiller, Alessandro C Pasqualotto
Fungi often infect mammalian hosts via the respiratory route, but traumatic transcutaneous implantation is also an important source of infections. Environmental exposure to spores of pathogenic fungi can result in subclinical and unrecognised syndromes, allergic manifestations, and even overt disease. After traumatic cutaneous inoculation, several fungi can cause neglected mycoses such as sporotrichosis, chromoblastomycosis, mycetoma, entomophthoramycosis, and lacaziosis. Most of these diseases have a subacute to chronic course and they can become recalcitrant to therapy and lead to physical disabilities, including inability to work, physical deformities, and amputations...
July 31, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28767670/comparing-tms-perturbations-to-occipital-and-parietal-cortices-in-concurrent-tms-fmri-studies-methodological-considerations
#20
COMPARATIVE STUDY
Joana Leitão, Axel Thielscher, Johannes Tuennerhoff, Uta Noppeney
Neglect and hemianopia are two neuropsychological syndromes that are associated with reduced awareness for visual signals in patients' contralesional hemifield. They offer the unique possibility to dissociate the contributions of retino-geniculate and retino-colliculo circuitries in visual perception. Yet, insights from patient fMRI studies are limited by heterogeneity in lesion location and extent, long-term functional reorganization and behavioural compensation after stroke. Transcranial magnetic stimulation (TMS) has therefore been proposed as a complementary method to investigate the effect of transient perturbations on functional brain organization...
2017: PloS One
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