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JOURNAL ARTICLE
Brittney S Lange-Maia, Maude Wagner, Christina A Rogers, Rupal I Mehta, David A Bennett, Christy Tangney, Michael E Schoeny, Shannon Halloway, Zoe Arvanitakis
High engagement in lifestyle health behaviors appears to be protective against cognitive decline in aging. We investigated the association between patterns of modifiable lifestyle health behaviors and common brain neuropathologies of dementia as a possible mechanism. We examined 555 decedents from the Rush Memory and Aging Project, free of dementia at their initial concurrent report of lifestyle health behaviors of interest (physical, social, and cognitive activities, and healthy diet) and who underwent a postmortem neuropathology evaluation...
April 10, 2024: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
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JOURNAL ARTICLE
Charles R Conway, Scott T Aaronson, Harold A Sackeim, Walter Duffy, Mary Stedman, João Quevedo, Rebecca M Allen, Patricio Riva-Posse, Matthew A Berger, Gustavo Alva, Mohd Azfar Malik, David L Dunner, Ivan Cichowicz, Heather Luing, John Zajecka, Ziad Nahas, Brian J Mickey, Anita S Kablinger, Christopher L Kriedt, Mark T Bunker, Ying-Chieh Lisa Lee, Olivia Shy, Shannon Majewski, Bryan Olin, Quyen Tran, A John Rush
BACKGROUND: RECOVER is a randomized sham-controlled trial of vagus nerve stimulation and the largest such trial conducted with a psychiatric neuromodulation intervention. OBJECTIVE: To describe pre-implantation baseline clinical characteristics and treatment history of patients with unipolar, major depressive disorder (MDD), overall and as a function of exposure to interventional psychiatric treatments (INTs), including electroconvulsive therapy, transcranial magnetic stimulation, and esketamine...
April 2, 2024: Brain Stimulation
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JOURNAL ARTICLE
Emily M Britton, Radia Taisir, Alysha Cooper, Shannon Remers, Yelena Chorny, Onawa LaBelle, Brian Rush, James MacKillop, Mary Jean Costello
Spirituality is an important aspect of treatment and recovery for substance use disorders (SUDs), but ambiguities in measurement can make it difficult to incorporate as part of routine care. We evaluated the psychometric properties of an adapted short-form version of the Spirituality Scale (the Spirituality Scale-Short-Form; SS-SF) for use in SUD treatment settings. Participants were adult patients ( N = 1,388; Mage = 41.23 years, SDage = 11.55; 68% male; 86% White) who entered a large, clinically mixed inpatient SUD treatment program...
December 31, 2023: Assessment
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JOURNAL ARTICLE
Emily W Paolillo, Rowan Saloner, Anna VandeBunte, Shannon Lee, David A Bennett, Kaitlin B Casaletto
BACKGROUND: Modifiable lifestyle behaviors account for a large proportion of dementia risk. However, the combined contributions of multidomain lifestyle patterns to cognitive aging are poorly understood, as most studies have examined individual lifestyle behaviors in isolation and without neuropathological characterization. This study examined data-driven patterns of lifestyle behaviors across multiple domains among older adults and tested their associations with disease-specific neuropathological burden and cognitive decline...
December 18, 2023: Alzheimer's Research & Therapy
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JOURNAL ARTICLE
Cecilia Flores-Sandoval, Joseph B Orange, Bridget L Ryan, Tracey L Adams, Neville Suskin, Robert McKelvie, Jacobi Elliott, Shannon L Sibbald
Transitional care to cardiac rehabilitation during the pandemic was a complex process for older adults, with additional challenges for decision-making and participation. This study aimed to explore the perspectives of older adults and health providers on transitional care from the hospital to cardiac rehabilitation, focusing on patient participation in decision-making. A qualitative exploratory design was used. Semi-structured interviews were conducted with 15 older adults and 6 healthcare providers. Document analysis and reflexive journaling were used to support triangulation of findings...
2023: Journal of Patient Experience
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JOURNAL ARTICLE
Sarah Bell, Taylor Orellana, Alison Garrett, Kenneth Smith, Haeyon Kim, Abigail Rosiello, Shannon Rush, Jessica Berger, Jamie Lesnock
OBJECTIVE: To determine our institutional rate of venous thromboembolism (VTE) following minimally invasive surgery for endometrial cancer and to perform a cost-effectiveness analysis of extended prophylactic anticoagulation after minimally invasive staging surgery for endometrial cancer. METHODS: All patients with newly diagnosed endometrial cancer who underwent minimally invasive staging surgery from January 1, 2017 to December 31, 2020 were identified retrospectively, and clinicopathologic and outcome data were obtained through chart review...
October 30, 2023: International Journal of Gynecological Cancer
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JOURNAL ARTICLE
Puja Agarwal, Christopher N Ford, Sue E Leurgans, Todd Beck, Pankaja Desai, Klodian Dhana, Denis A Evans, Shannon Halloway, Thomas M Holland, Kristin R Krueger, Xiaoran Liu, Kumar Bharat Rajan, David A Bennett
BACKGROUND: We have limited evidence for the relationship of high sugar intake with dementia risk. OBJECTIVE: To determine whether high sugar intake is associated with an increased risk of dementia in community-dwelling older adultsMethods:This study included 789 participants of the Rush Memory and Aging Project (community-based longitudinal cohort study of older adults free of known dementia at enrollment), with annual clinical assessments and complete nutrient data (obtained by validated food frequency questionnaire)...
2023: Journal of Alzheimer's Disease: JAD
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JOURNAL ARTICLE
Shannon Halloway, Maude Wagner, Christy Tangney, Brittney S Lange-Maia, David A Bennett, Zoe Arvanitakis, Michael E Schoeny
INTRODUCTION: We aimed to identify profiles of modifiable, late-life lifestyle health behaviors related to subsequent maintenance of cognition and explore sociodemographics and health characteristics as effect modifiers. METHODS: Analyses used data from 715 older adults without baseline dementia from the Rush Memory and Aging Project and with lifestyle health behaviors (physical activity, cognitive activity, healthy diet, social activity) at baseline and ≥ 2 annual assessments of cognition...
September 7, 2023: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
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JOURNAL ARTICLE
R Terik Daly, Carolyn M Ernst, Olivier S Barnouin, Nancy L Chabot, Andrew S Rivkin, Andrew F Cheng, Elena Y Adams, Harrison F Agrusa, Elisabeth D Abel, Amy L Alford, Erik I Asphaug, Justin A Atchison, Andrew R Badger, Paul Baki, Ronald-L Ballouz, Dmitriy L Bekker, Julie Bellerose, Shyam Bhaskaran, Bonnie J Buratti, Saverio Cambioni, Michelle H Chen, Steven R Chesley, George Chiu, Gareth S Collins, Matthew W Cox, Mallory E DeCoster, Peter S Ericksen, Raymond C Espiritu, Alan S Faber, Tony L Farnham, Fabio Ferrari, Zachary J Fletcher, Robert W Gaskell, Dawn M Graninger, Musad A Haque, Patricia A Harrington-Duff, Sarah Hefter, Isabel Herreros, Masatoshi Hirabayashi, Philip M Huang, Syau-Yun W Hsieh, Seth A Jacobson, Stephen N Jenkins, Mark A Jensenius, Jeremy W John, Martin Jutzi, Tomas Kohout, Timothy O Krueger, Frank E Laipert, Norberto R Lopez, Robert Luther, Alice Lucchetti, Declan M Mages, Simone Marchi, Anna C Martin, Maria E McQuaide, Patrick Michel, Nicholas A Moskovitz, Ian W Murphy, Naomi Murdoch, Shantanu P Naidu, Hari Nair, Michael C Nolan, Jens Ormö, Maurizio Pajola, Eric E Palmer, James M Peachey, Petr Pravec, Sabina D Raducan, K T Ramesh, Joshua R Ramirez, Edward L Reynolds, Joshua E Richman, Colas Q Robin, Luis M Rodriguez, Lew M Roufberg, Brian P Rush, Carolyn A Sawyer, Daniel J Scheeres, Petr Scheirich, Stephen R Schwartz, Matthew P Shannon, Brett N Shapiro, Caitlin E Shearer, Evan J Smith, R Joshua Steele, Jordan K Steckloff, Angela M Stickle, Jessica M Sunshine, Emil A Superfin, Zahi B Tarzi, Cristina A Thomas, Justin R Thomas, Josep M Trigo-Rodríguez, B Teresa Tropf, Andrew T Vaughan, Dianna Velez, C Dany Waller, Daniel S Wilson, Kristin A Wortman, Yun Zhang
While no known asteroid poses a threat to Earth for at least the next century, the catalog of near-Earth asteroids is incomplete for objects whose impacts would produce regional devastation1,2 . Several approaches have been proposed to potentially prevent an asteroid impact with Earth by deflecting or disrupting an asteroid1-3 . A test of kinetic impact technology was identified as the highest priority space mission related to asteroid mitigation1 . NASA's Double Asteroid Redirection Test (DART) mission is the first full-scale test of kinetic impact technology...
March 1, 2023: Nature
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JOURNAL ARTICLE
#11
REVIEW
Amrita Shahani, Harry Reyes Nieva, Katie Czado, Evan Shannon, Raquel Gaetani, Marcus Gresham, Jose Cruz Garcia, Hareesh Ganesan, Emily Cerciello, Janan Dave, Rahul Jain, Jeffrey L Schnipper
BACKGROUND: Adverse drug events are common during transitions of care. As part of the Smart Pillbox study, a cluster-randomized controlled trial of an electronic pillbox designed to reduce medication discrepancies and improve medication adherence after hospital discharge, we explored barriers to successful implementation and evaluation of this intervention. METHODS: Eligible patients were those admitted to a medicine service of a large teaching hospital with a plan to be discharged home on five or more chronic medications...
October 30, 2022: BMC Health Services Research
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JOURNAL ARTICLE
Shannon K Rush, Brittany F Lees, Dandi S Huang, Megan F Peterson, Ahmed Al-Niaimi
OBJECTIVES: We describe post-operative complications after cytoreductive surgery with and without splenectomy for Stage III or IV epithelial ovarian cancer, and identify areas for quality improvement in post-splenectomy care. METHODS: All patients with ovarian cancer cytoreductive surgery from 2008 to 2018 were identified using an institutional database Gynecologic Oncology Longitudinal Data Collection and Utilization Program (GOLD CUP). We compared patients who had and did not have splenectomy as part of cytoreductive surgery by demographics, comorbidities, stage, operative and post-operative data, readmission rates, progression free survival, overall survival and death from disease...
September 13, 2022: Gynecologic Oncology
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JOURNAL ARTICLE
Shubhabrata Mukherjee, Seo-Eun Choi, Michael L Lee, Phoebe Scollard, Emily H Trittschuh, Jesse Mez, Andrew J Saykin, Laura E Gibbons, R Elizabeth Sanders, Andrew F Zaman, Merilee A Teylan, Walter A Kukull, Lisa L Barnes, David A Bennett, Andrea Z Lacroix, Eric B Larson, Michael Cuccaro, Shannon Mercado, Logan Dumitrescu, Timothy J Hohman, Paul K Crane
OBJECTIVE: Studies use different instruments to measure cognitirating cognitive tests permit direct comparisons of individuals across studies and pooling data for joint analyses. METHOD: We began our legacy item bank with data from the Adult Changes in Thought study ( n = 5,546), the Alzheimer's Disease Neuroimaging Initiative ( n = 3,016), the Rush Memory and Aging Project ( n = 2,163), and the Religious on such as the Mini-Mental State Examination, the Alzheimer's Disease Assessment Scale-Cognitive Subscale, the Wechsler Memory Scale, and the Boston Naming Test...
August 4, 2022: Neuropsychology
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JOURNAL ARTICLE
Liu Yang, Zhenxing Shen, Junqiang Wei, Xiuru Wang, Hongmei Xu, Jian Sun, Qiyuan Wang, Junji Cao
Bioaerosols have become a major environmental concern in recent years. In this study, the diurnal variations and size distributions of bioaerosols, as well as airborne bacterial community compositions and their influencing factors on haze and non-haze days in Xi'an, China, were compared. The results indicated that the mean bacteria and fungi concentrations on non-haze days were 1.7 and 1.4 times of those on haze days, respectively, whereas the mean total airborne microbe (TAM) concentration was higher on haze days...
September 10, 2022: Science of the Total Environment
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REVIEW
Shannon K Rush, Xiuyu Ma, Michael A Newton, Stephen L Rose
OBJECTIVE: To perform an updated Markov modeling to assess the optimal age for bilateral salpingo-oophorectomy (BSO) at the time of hysterectomy for benign indication. METHODS: We performed a literature review that assessed hazard ratios (HRs) for mortality by disease, age, hysterectomy with or without BSO, and estrogen therapy use. Base mortality rates were derived from national vital statistics data. A Markov model from reported HRs predicted the proportion of the population staying alive to age 80 years by 1-year and 5-year age groups at time of surgery, from age 45 to 55 years...
May 1, 2022: Obstetrics and Gynecology
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JOURNAL ARTICLE
Mary Jean Costello, Yao Li, Yeying Zhu, Alyna Walji, Sarah Sousa, Shannon Remers, Yelena Chorny, Brian Rush, James MacKillop
BACKGROUND: Continuing care following inpatient addiction treatment is an important component in the continuum of clinical services. Mutual help, including 12-step groups like Alcoholics Anonymous, is often recommended as a form of continuing care. However, the effectiveness of 12-step groups is difficult to establish using observational studies due to the risks of selection bias (or confounding). OBJECTIVE: To address this limitation, we used both conventional and machine learning-based propensity score (PS) methods to examine the effectiveness of 12-step group involvement following inpatient treatment on substance use over a 12-month period...
October 1, 2021: Drug and Alcohol Dependence
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JOURNAL ARTICLE
Dror Paley, Claire E Shannon, Monica Nogueira, Catharina Chiari, Matthew Harris
Congenital femoral deficiency (CFD) Paley type 1b is characterized by severe bony deformity of the upper femur, extra-articular contractures of the hip, and, delayed ossification of the femoral neck and/or subtrochanteric region. The Systematic Utilitarian Procedure for Extremity Reconstruction of the hip (SUPERhip) procedure for the correction of CFD deformities was developed in 1997. Initially, a non-fixed angle device (rush rod) was used for fixation. Late complications of persistent delayed ossification and recurrent varus deformity occurred...
June 10, 2021: Children
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JOURNAL ARTICLE
Kate Corrigan, Maeve Haran, Conor McCandliss, Roisin McManus, Shannon Cleary, Rebecca Trant, Yazeed Kelly, Kathryn Ledden, Gavin Rush, Veronica O'Keane, John R Kelly
INTRODUCTION: Despite the rapid advance of psychedelic science and possible translation of psychedelic therapy into the psychiatric clinic, very little is known about mental health service user attitudes. OBJECTIVES: To explore mental health service user attitudes to psychedelics and psilocybin therapy. METHODS: A questionnaire capturing demographics, diagnoses, previous psychedelic and other drug use, and attitudes to psychedelics and psilocybin therapy was distributed to mental health service users...
June 15, 2021: Irish Journal of Medical Science
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JOURNAL ARTICLE
Crystal A Shannon, Lise L Olsen, Rachelle Hole, Kathy L Rush
BACKGROUND: Children with autism spectrum disorder (ASD) and their families experience challenges and barriers at multiple levels that influence their activity participation. The purpose of this study was to develop understanding about factors influencing how families can promote safe, active recreation for their children 3-12 years living with ASD across rural settings and how supports for these families can be enhanced. METHODS: This qualitative study used an interpretive descriptive approach...
August 2021: Research in Developmental Disabilities
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JOURNAL ARTICLE
Erin Hetherington, Sarah A Edwards, Shannon E MacDonald, Nicole Racine, Sheri Madigan, Sheila McDonald, Suzanne Tough
BACKGROUND: Acceptance of a vaccine against SARS-CoV-2 is critical to achieving high levels of immunization. The objectives of this study were to understand mothers' SARS-CoV-2 vaccine intentions to explore reasons for and against SARS-CoV-2 vaccination. METHODS: Participants from the All Our Families pregnancy longitudinal cohort whose children had reached ages 9-12 years were invited in May-June 2020 to complete a survey on the impact of COVID-19. The survey covered topics about the impact of the pandemic and included 2 specific questions on mothers' intentions to vaccinate their child against SARS-CoV-2...
April 2021: CMAJ Open
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