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https://www.readbyqxmd.com/read/26508315/policing-the-epidemic-high-burden-of-workplace-violence-among-female-sex-workers-in-conflict-affected-northern-uganda
#1
Katherine A Muldoon, Monica Akello, Godfrey Muzaaya, Annick Simo, Jean Shoveller, Kate Shannon
Sex workers in sub-Saharan Africa experience a high burden of HIV with a paucity of data on violence and links to HIV risk among sex workers, and even less within conflict-affected environments. Data are from a cross-sectional survey of female sex workers in Gulu, northern Uganda (n = 400). Logistic regression was used to determine the specific association between policing and recent physical/sexual violence from clients. A total of 196 (49.0%) sex workers experienced physical/sexual violence by a client...
October 27, 2015: Global Public Health
https://www.readbyqxmd.com/read/26385574/minimally-invasive-approach-to-achilles-tendon-pathology
#2
Kenneth W Hegewald, Matthew D Doyle, Nicholas W Todd, Shannon M Rush
Many surgical procedures have been described for Achilles tendon pathology; however, no overwhelming consensus has been reached for surgical treatment. Open repair using a central or paramedian incision allows excellent visualization for end-to-end anastomosis in the case of a complete rupture and detachment and reattachment for insertional pathologies. Postoperative wound dehiscence and infection in the Achilles tendon have considerable deleterious effects on overall functional recovery and outcome and sometimes require plastic surgery techniques to achieve coverage...
January 2016: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/26118326/structural-determinants-of-dual-contraceptive-use-among-female-sex-workers-in-gulu-northern-uganda
#3
Margaret Erickson, Shira M Goldenberg, Mirriam Ajok, Katherine A Muldoon, Godfrey Muzaaya, Kate Shannon
OBJECTIVE: To describe the characteristics of female sex workers (FSWs) who do and do not use dual contraceptives (i.e. male condoms plus a non-barrier method) in Gulu, northern Uganda. METHODS: The present analysis was based on data gathered as part of a questionnaire-based, cross-sectional study conducted between May 2011 and January 2012. FSWs aged 14 years or older were recruited through peer-led or sex worker-led outreach and community-based services. Logistic regression was used to identify correlates of dual contraceptive use...
October 2015: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/25878081/understanding-the-postoperative-course-and-rehabilitation-protocol-for-total-ankle-arthroplasty
#4
Carroll Jones, Shannon Rush, Gregory C Berlet, Jeremy Regina, Murray Penner, Stephen A Brigido, W Bret Smith, Stephen A Brigido
No abstract text is available yet for this article.
June 2015: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/25681595/optimizations-and-nuances-in-neurosurgical-technique-for-the-minimization-of-complications-in-subdural-electrode-placement-for-epilepsy-surgery
#5
Steven M Falowski, Daniel J DiLorenzo, Larry R Shannon, David J Wallace, James Devries, Robert G Kellogg, Nicholas P Cozzi, Lou F Fogg, Richard W Byrne
BACKGROUND: Surgical intervention is an important therapeutic option for patients with intractable epilepsy and a well-characterized epileptogenic focus. Invasive monitoring with subdural electrodes is an effective technique for localizing epileptogenic foci. Previous studies reported varying complication rates, and these may deter more widespread adoption. We present potentially valuable technical nuances that may be associated with low complication rates. We assess the potential contribution of specific aspects of surgical technique to the reduction of complication rates...
October 2015: World Neurosurgery
https://www.readbyqxmd.com/read/25480830/a-phase-i-study-of-oral-arry-614-a-p38-mapk-tie2-dual-inhibitor-in-patients-with-low-or-intermediate-1-risk-myelodysplastic-syndromes
#6
MULTICENTER STUDY
Guillermo Garcia-Manero, Hanna J Khoury, Elias Jabbour, Jeffrey Lancet, Shannon L Winski, LouAnn Cable, Selena Rush, Lara Maloney, Grant Hogeland, Mieke Ptaszynski, Monica Cabrero Calvo, Zach Bohannan, Alan List, Hagop Kantarjian, Rami Komrokji
PURPOSE: Data suggest that activity of p38 MAPK and Tie2 kinases is dysregulated in myelodysplastic syndromes (MDS) and may be targets for novel therapies. A phase I study of ARRY-614, an oral dual inhibitor of p38 MAPK and Tie2, was conducted in patients with low or intermediate-1 International Prognostic Scoring System risk MDS to evaluate safety, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary responses by International Working Group 2006 criteria. EXPERIMENTAL DESIGN: Forty-five patients received ARRY-614 either once daily or twice daily in dose escalation (400, 600, 900, or 1,200 mg once daily; 200 or 300 mg twice daily) or expansion cohorts...
March 1, 2015: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/25191595/plasma-25-hydroxyvitamin-d3-folate-and-vitamin-b12-biomarkers-among-international-colorectal-cancer-patients-a-pilot-study
#7
Cornelia M Ulrich, Adetunji T Toriola, Erin M Siegel, Hermann Brenner, Jenny Chang-Claude, Clare Abbenhardt, Jana Kotzmann, Xiaoling Song, Robert W Owen, Michael Hoffmeister, Heiko Becher, David Shibata, Kathy Vickers, Shannon K Rush, Karen Makar, Gerd Würtele, Roswitha Haubner, Thomas A Sellers, William Grady
Vitamin D and folate are associated with decreased colorectal cancer risk and their association with colorectal cancer prognosis is under investigation. We assessed the levels of plasma 25-hydroxyvitamin D3 (25(OH)D3), folate and vitamin B12 in an international pilot study in order to determine variability of these biomarkers based on geographical location. Plasma 25(OH)D3, folate and vitamin B12 concentrations were measured in 149 invasive, newly diagnosed colorectal cancer cases from Heidelberg (Germany), Seattle (WA, USA), and Tampa (FL, USA) and in ninety-one age- and sex-matched controls...
2013: Journal of Nutritional Science
https://www.readbyqxmd.com/read/24889853/criminalisation-of-clients-reproducing-vulnerabilities-for-violence-and-poor-health-among-street-based-sex-workers-in-canada-a-qualitative-study
#8
A Krüsi, K Pacey, L Bird, C Taylor, J Chettiar, S Allan, D Bennett, J S Montaner, T Kerr, K Shannon
OBJECTIVES: To explore how criminalisation and policing of sex buyers (clients) rather than sex workers shapes sex workers' working conditions and sexual transactions including risk of violence and HIV/sexually transmitted infections (STIs). DESIGN: Qualitative and ethnographic study triangulated with sex work-related violence prevalence data and publicly available police statistics. SETTING: Vancouver, Canada, provides a unique opportunity to evaluate the impact of policies that criminalise clients as the local police department adopted a sex work enforcement policy in January 2013 that prioritises sex workers' safety over arrest, while continuing to target clients...
June 2, 2014: BMJ Open
https://www.readbyqxmd.com/read/24840733/pulmonary-pleomorphic-carcinoma-metastasis-to-the-midfoot
#9
Brittany Rice, Justin Ross, Nicholas Todd, Louis Caputo, Shannon Rush, Bijayee Shrestha
Metastases to the bones in the foot are extremely uncommon, occurring in approximately 0.01% of all metastatic bone disease. We describe a case of an 82-year-old female with a metastatic pulmonary sarcomatoid carcinoma lesion to the midfoot. This rare and aggressive pulmonary malignancy has a poor prognosis. The purpose of the present case report was to highlight the key roles that medical history and biopsy, combined with a multispecialty approach, play in accurately diagnosing and appropriately treating a patient with metastatic bone disease...
May 2015: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/24173967/phase-i-study-of-dasatinib-in-combination-with-capecitabine-oxaliplatin-and-bevacizumab-followed-by-an-expanded-cohort-in-previously-untreated-metastatic-colorectal-cancer
#10
John H Strickler, Shannon McCall, Andrew B Nixon, John C Brady, Herbert Pang, Christel Rushing, Allen Cohn, Alexander Starodub, Christy Arrowood, Sherri Haley, Kellen L Meadows, Michael A Morse, Hope E Uronis, Gerard C Blobe, S David Hsu, S Yousuf Zafar, Herbert I Hurwitz
PURPOSE: Dasatinib inhibits src family kinases and has anti-angiogenic properties. We conducted a phase I study of dasatinib, capecitabine, oxaliplatin, and bevacizumab (CapeOx/bevacizumab), with an expansion cohort in metastatic colorectal cancer (CRC). METHODS: Patients were enrolled in a dose escalation cohort to establish the maximum tolerated dose (MTD) and the recommended phase II dose (RP2D). Using a "3 + 3" design, twelve patients with advanced solid tumors received dasatinib (50 mg twice daily or 70 mg daily), capecitabine (850 mg/m(2) twice daily, days 1-14), oxaliplatin (130 mg/m(2) on day 1) and bevacizumab (7...
April 2014: Investigational New Drugs
https://www.readbyqxmd.com/read/24160724/modified-blair-tibiotalar-arthrodesis-for-post-traumatic-avascular-necrosis-of-the-talus-a-case-report
#11
Justin S Ross, Shannon M Rush, Nicholas W Todd, Meagan M Jennings
Surgical treatment of post-traumatic avascular necrosis of the talus coupled with collapse often results in limited treatment options. Of those options, the Blair tibiotalar arthrodesis has been beneficial in preserving limb length and subtalar motion. The complications associated with Blair tibiotalar arthrodesis have led to modifications to improve stability and functional outcomes with rigid internal fixation. We present the case of a 29-year-old female with a history of an open fracture dislocation of the talus 10 years previously, with subsequent development of avascular necrosis of the talus...
November 2013: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/23970438/dpm-foot-and-ankle-fellowships
#12
Jeffrey E McAlister, Christopher F Hyer, J Michael Miller, Shannon Rush, Amol Saxena, John S Steinberg, Lowell Weil
No abstract text is available yet for this article.
October 2013: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/23871174/metastatic-calcaneal-lesion-associated-with-uterine-carcinosarcoma
#13
Brittany M Rice, Nicholas W Todd, Richard Jensen, Shannon M Rush, William Rogers
Metastatic lesions of uterine carcinosarcoma most commonly occur in the abdomen and lungs and less frequently in highly vascularized bone. We report a rare case of an 86-year-old female with uterine carcinosarcoma with metastasis to the left calcaneus. The patient had a history of uterine carcinosarcoma with hysterectomy and bilateral salpingo-oophorectomy, along with bilateral pelvic and aortic lymphadenectomy, with no adjuvant therapy. The initial pedal complaint was that of left foot pain. The initial radiographic findings were negative; however, magnetic resonance imaging scans revealed a substantial area of marrow edema in the calcaneus...
May 2014: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/23618955/a-physical-sciences-network-characterization-of-non-tumorigenic-and-metastatic-cells
#14
David B Agus, Jenolyn F Alexander, Wadih Arap, Shashanka Ashili, Joseph E Aslan, Robert H Austin, Vadim Backman, Kelly J Bethel, Richard Bonneau, Wei-Chiang Chen, Chira Chen-Tanyolac, Nathan C Choi, Steven A Curley, Matthew Dallas, Dhwanil Damania, Paul C W Davies, Paolo Decuzzi, Laura Dickinson, Luis Estevez-Salmeron, Veronica Estrella, Mauro Ferrari, Claudia Fischbach, Jasmine Foo, Stephanie I Fraley, Christian Frantz, Alexander Fuhrmann, Philippe Gascard, Robert A Gatenby, Yue Geng, Sharon Gerecht, Robert J Gillies, Biana Godin, William M Grady, Alex Greenfield, Courtney Hemphill, Barbara L Hempstead, Abigail Hielscher, W Daniel Hillis, Eric C Holland, Arig Ibrahim-Hashim, Tyler Jacks, Roger H Johnson, Ahyoung Joo, Jonathan E Katz, Laimonas Kelbauskas, Carl Kesselman, Michael R King, Konstantinos Konstantopoulos, Casey M Kraning-Rush, Peter Kuhn, Kevin Kung, Brian Kwee, Johnathon N Lakins, Guillaume Lambert, David Liao, Jonathan D Licht, Jan T Liphardt, Liyu Liu, Mark C Lloyd, Anna Lyubimova, Parag Mallick, John Marko, Owen J T McCarty, Deirdre R Meldrum, Franziska Michor, Shannon M Mumenthaler, Vivek Nandakumar, Thomas V O'Halloran, Steve Oh, Renata Pasqualini, Matthew J Paszek, Kevin G Philips, Christopher S Poultney, Kuldeepsinh Rana, Cynthia A Reinhart-King, Robert Ros, Gregg L Semenza, Patti Senechal, Michael L Shuler, Srimeenakshi Srinivasan, Jack R Staunton, Yolanda Stypula, Hariharan Subramanian, Thea D Tlsty, Garth W Tormoen, Yiider Tseng, Alexander van Oudenaarden, Scott S Verbridge, Jenny C Wan, Valerie M Weaver, Jonathan Widom, Christine Will, Denis Wirtz, Jonathan Wojtkowiak, Pei-Hsun Wu
To investigate the transition from non-cancerous to metastatic from a physical sciences perspective, the Physical Sciences-Oncology Centers (PS-OC) Network performed molecular and biophysical comparative studies of the non-tumorigenic MCF-10A and metastatic MDA-MB-231 breast epithelial cell lines, commonly used as models of cancer metastasis. Experiments were performed in 20 laboratories from 12 PS-OCs. Each laboratory was supplied with identical aliquots and common reagents and culture protocols. Analyses of these measurements revealed dramatic differences in their mechanics, migration, adhesion, oxygen response, and proteomic profiles...
2013: Scientific Reports
https://www.readbyqxmd.com/read/23164440/salto-talaris-fixed-bearing-total-ankle-replacement-system
#15
REVIEW
Shannon M Rush, Nicholas Todd
The Salto Talaris total ankle replacement is an anatomically designed fixed bearing prosthesis available in the United States based on the successful design of the mobile-bearing Salto prosthesis available outside the United States. The original mobile-bearing design was modified and the mobile-bearing was transferred to the precision instrumentation at the trial phase evaluation. Instrumentation and technique allow the surgeon to determine the functional joint axis before final implantation. The Salto Talaris total ankle replacement design blends minimal bone resection and optimizes surface area, cortical contact, and ultra-high molecular weight polyethylene conformity...
January 2013: Clinics in Podiatric Medicine and Surgery
https://www.readbyqxmd.com/read/22966858/the-small-gtpase-rhog-mediates-glioblastoma-cell-invasion
#16
Aneta Kwiatkowska, Sebastien Didier, Shannon Fortin, Yayu Chuang, Timothy White, Michael E Berens, Elisabeth Rushing, Jennifer Eschbacher, Nhan L Tran, Amanda Chan, Marc Symons
BACKGROUND: The invasion of glioblastoma cells into regions of the normal brain is a critical factor that limits current therapies for malignant astrocytomas. Previous work has identified roles for the Rho family guanine nucleotide exchange factors Trio and Vav3 in glioblastoma invasion. Both Trio and Vav3 act on the small GTPase RhoG. We therefore examined the role of RhoG in the invasive behavior of glioblastoma cells. RESULTS: We found that siRNA-mediated depletion of RhoG strongly inhibits invasion of glioblastoma cells through brain slices ex vivo...
2012: Molecular Cancer
https://www.readbyqxmd.com/read/22267863/locking-plates
#17
Stephen K Benirschke, Shannon M Rush, Robert N Reddix, Hans Zwipp, Brian Carpenter, John M Schuberth
No abstract text is available yet for this article.
February 2012: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/22188904/complications-associated-with-foot-and-ankle-arthroscopy
#18
MULTICENTER STUDY
David F Deng, Graham A Hamilton, Michael Lee, Shannon Rush, Lawrence A Ford, Sandeep Patel
Despite a late start within the realm of arthroscopy, foot and ankle arthroscopy proves to be an important diagnostic and treatment tool for the foot and ankle specialist. As indication for arthroscopy increases, complications associated with foot and ankle arthroscopy must be revisited. We reviewed 405 foot and ankle arthroscopic procedures performed on 390 patients in 4 different facilities over a 3-year period extending from January 2005 to August 2008. Two-hundred-sixty foot and ankle arthroscopic procedures on 251 patients met our inclusion criteria...
May 2012: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/21799213/childhood-trauma-and-hippocampal-and-amygdalar-volumes-in-first-episode-psychosis
#19
Katrina Hoy, Suzanne Barrett, Ciaran Shannon, Clodagh Campbell, David Watson, Teresa Rushe, Mark Shevlin, Feng Bai, Stephen Cooper, Ciaran Mulholland
OBJECTIVE: A history of childhood trauma is common in individuals who later develop psychosis. Similar neuroanatomical abnormalities are observed in people who have been exposed to childhood trauma and people with psychosis. However, the relationship between childhood trauma and such abnormalities in psychosis has not been investigated. This study aimed to explore the association between the experience of childhood trauma and hippocampal and amygdalar volumes in a first-episode psychosis (FEP) population...
November 2012: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/21354002/radiographic-outcomes-of-adult-acquired-flatfoot-corrected-by-medial-column-arthrodesis-with-or-without-a-medializing-calcaneal-osteotomy
#20
Thomas H Jordan, Shannon M Rush, Graham A Hamilton, Lawrence A Ford
Medial column arthrodesis and calcaneal osteotomies are commonly used for adult acquired flatfoot surgical reconstruction. In this retrospective study, 41 patients (47 feet) with a mean age of 55 ± 13.5 years underwent a medial column arthrodesis, with or without calcaneal osteotomy, between 1999 and 2007. The indication for surgery was a painful flatfoot deformity with peritalar subluxation, and a fault in the naviculocuneiform joint. At a mean of 9.6 (range 3-43) months postoperatively, in patients who underwent a medial column arthrodesis, radiographs showed a mean decrease in the talonavicular coverage angle of 10...
March 2011: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
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