Antonio Greco, Giovanni Occhipinti, Daniele Giacoppo, Federica Agnello, Claudio Laudani, Marco Spagnolo, Maria Sara Mauro, Carla Rochira, Simone Finocchiaro, Placido Maria Mazzone, Denise Cristiana Faro, Davide Landolina, Nicola Ammirabile, Antonino Imbesi, Carmelo Raffo, Davide Capodanno
Stroke is a devastating condition with significant morbidity and mortality worldwide. Antithrombotic therapy plays a crucial role in both primary and secondary prevention of stroke events. Single or dual antiplatelet therapy is generally preferred in cases of large-artery atherosclerosis and small-vessel disease, whereas anticoagulation is recommended in conditions of blood stasis or hypercoagulable states that mostly result in red thrombi. However, the benefit of antithrombotic therapies must be weighed against the increased risk of bleeding, which can pose significant challenges in the pharmacological management of this condition...
October 10, 2023: Journal of the American College of Cardiology