Gabriella Bottari, Bianca Maria Goffredo, Marco Marano, Cristina Maccarrone, Raffaele Simeoli, Giuseppe Bianco, Leonardo Vallesi, Joseph Charles Charlie Beetham, Anna Teresa Mazzeo, Andrea Cappoli, Sara Cairoli, Raffaella Labbadia, Corrado Cecchetti, Paola Bernaschi, Tiziana Corsetti, Santo Morabito, Fabio Silvio Taccone, Isabella Guzzo
Background: Extracorporeal therapies (ET) are increasingly used in pediatric settings as adjuvant therapeutic strategies for overwhelming inflammatory conditions. Although these treatments seem to be effective for removing inflammatory mediators, their influence on antimicrobials pharmacokinetic should not be neglected. Methods: A prospective observational study of children admitted to the pediatric intensive care unit (PICU) with a diagnosis of sepsis/septic shock. All critically ill children received hemoadsorption treatment with CytoSorb (CS) in combination with CKRT...
August 31, 2023: Antibiotics