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maternal and perinatal outcomes of macrosomic baby

Vidushi Kulshrestha, Nutan Agarwal
Diabetes in pregnancy starts affecting the foetus even in the pre-conception period. The complications encountered in third trimester are foetal macrosomia and intrauterine foetal demise; birth of a macrosomic baby further leads to shoulder dystocia, birth trauma, brachial plexus injury. Additionally, pregnancies with overt/pregestational diabetes may be complicated with foetal growth restriction, congenital abnormalities diagnosed in third trimester and foetal hypertrophic obstructive cardiomyopathy. Even minor degrees of hyperglycaemia is associated with adverse pregnancy outcome...
September 2016: JPMA. the Journal of the Pakistan Medical Association
Aisha Salim Said, Karim Premji Manji
BACKGROUND: Fetal macrosomia is defined as birth weight ≥4000 g. Several risk factors have been shown to be associated with fetal macrosomia. There has been an increased incidence of macrosomic babies delivered and the antecedent complications. This study assessed the risk factors, maternal and neonatal complications of fetal macrosomia in comparison with normal birth weight neonates. METHODS: A case-control study was conducted at the Muhimbili National Hospital (MNH) maternity and neonatal wards...
2016: BMC Pregnancy and Childbirth
Michel Boulvain, Olivier Irion, Therese Dowswell, Jim G Thornton
BACKGROUND: Women with a suspected large-for-dates fetus or a fetus with suspected macrosomia (birthweight greater than 4000 g) are at risk of operative birth or caesarean section. The baby is also at increased risk of shoulder dystocia and trauma, in particular fractures and brachial plexus injury. Induction of labour may reduce these risks by decreasing the birthweight, but may also lead to longer labours and an increased risk of caesarean section. OBJECTIVES: To assess the effects of a policy of labour induction at or shortly before term (37 to 40 weeks) for suspected fetal macrosomia on the way of giving birth and maternal or perinatal morbidity...
2016: Cochrane Database of Systematic Reviews
Oghenefegor Edwin Olokor, Joseph Ubini Onakewhor, Adeniyi Kolade Aderoba
BACKGROUND: To determine the incidence and risk factors of fetal macrosomia and maternal and perinatal outcome. PATIENTS AND METHODS: This was a 1-year prospective case-control study of singleton pregnancies in a Nigerian tertiary hospital. Only women who gave consent were recruited for the study. The maternal and perinatal outcomes in women who delivered macrosomic infants (birth weight ≥ 4000 g) were compared with the next consecutive delivery of normal birth weight (2500-3999 g) infants...
November 2015: Nigerian Medical Journal: Journal of the Nigeria Medical Association
Angela Elena Vinturache, Sheila McDonald, Donna Slater, Suzanne Tough
The objective of this study was to assess the impact of increased pre-pregnancy maternal body mass index (BMI) on perinatal outcomes in term, singleton pregnancies who received prenatal care in community-based practices. The sample of 1996 infants included in the study was drawn from the All Our Babies Study, a prospective pregnancy cohort from Calgary. Multivariable logistic regression explored the relationship between the main outcomes, infant birth weight, Apgar score, admission to neonatal intensive care (NICU) and newborn duration of hospitalization, and BMI prior to pregnancy...
2015: Scientific Reports
Kelly L Morgan, Muhammad A Rahman, Rebecca A Hill, Shang-Ming Zhou, Gunnar Bijlsma, Ashrafunnesa Khanom, Ronan A Lyons, Sinead T Brophy
BACKGROUND: This study examines the effect of low daily physical activity levels and overweight/obesity in pregnancy on delivery and perinatal outcomes. METHODS: A prospective cohort study combining manually collected postnatal notes with anonymised data linkage. A total of 466 women sampled from the Growing Up in Wales: Environments for Healthy Living study. Women completed a questionnaire and were included in the study if they had an available Body mass index (BMI) (collected at 12 weeks gestation from antenatal records) and/or a physical activity score during pregnancy (7-day Actigraph reading)...
2014: PloS One
Mamta Bhat, K N Ramesha, Sankara P Sarma, Sangeetha Menon, S Ganesh Kumar
BACKGROUND: Carbohydrate intolerance is the most common metabolic complication of pregnancy. Gestational diabetes mellitus (GDM) poses numerous problems for both mother and fetus. The objective of this study was to compare the maternal and perinatal outcome between women with gestational diabetes mellitus and non-diabetic women. STUDY DESIGN: A case-control study with 286 cases and 292 age-matched controls was conducted for a period of 11 months (August 2007-June 2008) in Sree Avittom Thirunal Hospital, Thiruvananthapuram, India...
December 2012: Journal of Obstetrics and Gynaecology of India
Shanshan Han, Caroline A Crowther, Philippa Middleton, Emer Heatley
BACKGROUND: Gestational diabetes mellitus (GDM) affects a significant number of women each year and is associated with a wide range of adverse outcomes for women and their babies. Dietary counselling is the main strategy in managing GDM, but it remains unclear which dietary therapy is best. OBJECTIVES: To assess the effects of different types of dietary advice for women with GDM on pregnancy outcomes. SEARCH METHODS: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (17 May 2012) and the WOMBAT Perinatal Trials Registry (17 April 2012)...
2013: Cochrane Database of Systematic Reviews
Ai Koyanagi, Jun Zhang, Amarjargal Dagvadorj, Fumi Hirayama, Kenji Shibuya, João Paulo Souza, Ahmet Metin Gülmezoglu
BACKGROUND: Macrosomia is a risk factor for adverse delivery outcomes. We investigated the prevalence, risk factors, and delivery outcomes of babies with macrosomia in 23 developing countries in Africa, Asia, and Latin America. METHODS: We analysed data from WHO's Global Survey on Maternal and Perinatal Health, which was a facility-based cross-sectional study that obtained data for women giving birth in 373 health facilities in 24 countries in Africa and Latin America in 2004-05, and in Asia in 2007-08...
February 9, 2013: Lancet
Niranjan Thomas, Annie Jothirmayi Chinta, Santhanam Sridhar, Manish Kumar, Kurien Anil Kuruvilla, Atanu Kumar Jana
OBJECTIVE: To study the perinatal outcomes of infants born to mothers with gestational diabetes treated with insulin or oral hypoglycemic agents in a developing country. DESIGN: Prospective observational cohort study. SETTING: Tertiary-care perinatal center in southern India. PARTICIPANTS: Babies born to mothers with gestational diabetes. METHODS: Maternal details were obtained and physical examination was performed on the neonates...
March 2013: Indian Pediatrics
Saada Ahmed, Ewa Romejko-Wolniewicz, Julia Zaręba-Szczudlik, Krzysztof Czajkowski
OBJECTIVES: Fetal macrosomia is defined as a fetus that is of large size for gestational age, i.e. equal to or greater than the 90th percentile of weight. There is some evidence of increased perinatal mortality and morbidity rates in cases of macrosomia. DESIGN: This is a retrospective study of patients with term pregnancy. We analyzed the deliveries of 508 infants born with birth weight ≥ 4 200 grams and considered them as a study group. The deliveries of newborns with birth weight less than 4 000 g constituted the control group (330 cases)...
2012: Neuro Endocrinology Letters
Françoise Vendittelli, Olivier Rivière, Gérard Bréart
OBJECTIVES: To determine whether prenatal identification of macrosomia (≥4000g) reduces neonatal complications and maternal perineal lesions during delivery. STUDY DESIGN: This historical cohort study (n=14,684 from the National perinatal database of the Audipog Association, France) included women with cephalic singleton term pregnancies. Among the babies born with macrosomia, we compared those who had been identified as such in utero (n=1211) with those who were not (n=13,473)...
April 2012: European Journal of Obstetrics, Gynecology, and Reproductive Biology
H U Ezegwui, L C Ikeako, C Egbuji
BACKGROUND: In modern obstetrics, fetal macrosomia is a major contributor to obstetric morbidity. It is an important cause of perinatal morbidity and mortality. AIM: This study aims to determine the maternal characteristics, fetal and neonatal complications associated with fetal macrosomia, and its contribution to obstetric morbidity in Enugu, Nigeria. MATERIALS AND METHODS: This was a 3-year retrospective study carried out from 1 st January 2005 to 31 st December 2007...
July 2011: Nigerian Journal of Clinical Practice
A Di Benedetto, R D'anna, M L Cannata, D Giordano, M L Interdonato, F Corrado
AIM: The aim of this study was to determine the effects of maternal prepregnancy body mass index (BMI) and weight gain during pregnancy on perinatal outcome in non-diabetic women. METHODS: The clinical records of consecutive women who had undergone a glucose challenge test (GCT) and then delivered in our university hospital between January 2004 and December 2009 were retrospectively reviewed. Prepregnancy BMI and pregnancy weight gain were classified according to the US Institute of Medicine guidelines (1990)...
February 2012: Diabetes & Metabolism
Chiraz El Fekih, Mechaal Mourali, Nadia Ouerdiane, Seddik Oueslati, Amine Hadj Hassine, Mounira Chaabene, Nabil Ben Zineb
AIM: To review the deliveries of macrosomic babies, weighing over than 4000g and their obstetrical and neonatal outcomes. METHODS: Retrospective study involving a total of 209 deliveries at term of macrosomic babies between Marsh 2006 and February 2007 in the Maternity Hospital of Mahmoud ELMATRI, Tunis. The study concerned risk factors, mode of delivery and the incidence of maternal and perinatal complications.We compared data in the study group to a control group of normal weight infants delivered at the same period...
June 2011: La Tunisie Médicale
J D Ojule, P O Fiebai, C Okongwu
BACKGROUND: Macrosomic babies are at increased risk of adverse perinatal outcome and therefore constitute a high risk group of neonates and the incidence appears to be rising. The objective was to determine the incidence of fetal macrosomia, and the perinatal outcome of macrosomic babies, compare with matched term, appropriate weight neonates in the booked antenatal population of the UPTH. METHODS: It was a one year prospective study of the perinatal outcome of singleton babies whose birth weights were 4000 g and above (macrosomia) delivered to booked antenatal mothers in UPTH between 1st October 2003 and 30th September 2004, comparing them with term appropriate (2500-3999 g) weight babies...
October 2010: Nigerian Journal of Medicine: Journal of the National Association of Resident Doctors of Nigeria
U Mazumder, S Sarker, B K Riaz, T A Chowdhury
Obesity in pregnancy remains a significant health problem that result in physiological, emotional, social and economic consequences on woman, their families and society. Obesity is considered one of the nutritional problems complicating pregnancy in our country. This study was conducted in antenatal clinic at out patient department of Obstetrics & Gynecology, BIRDEM Hospital, one of the countries largest tertiary level hospitals, during January 2007 to December 2008. During the study period of two years, a total no...
April 2011: Mymensingh Medical Journal: MMJ
Ning Liu, Shi Wu Wen, Wendy Katherine, Jim Bottomley, Qiuying Yang, Mark C Walker
OBJECTIVE: to assess the association between neighbourhood family income and adverse birth outcomes. METHODS: we conducted a retrospective cohort study of 334 231 singleton births during 2004 and 2006 based on the Niday Perinatal Database from Ontario. Median neighbourhood family incomes from the 2001 Canadian census were linked with the Niday Perinatal Database by dissemination areas. Generalized estimating equations were applied to estimate the odds ratios of adverse birth outcomes associated with lower neighbourhood income, with adjustment for maternal confounding variables at the individual level...
November 2010: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
Peace I Opara, Tamunopriye Jaja, Uche C Onubogu
BACKGROUND: Infants born to diabetic women have certain distinctive characteristics, including large size and high morbidity risks. The neonatal mortality rate is over five times that of infants of non diabetic mothers and is higher at all gestational ages and birth weight for gestational age (GA) categories.The study aimed to determine morbidity and mortality pattern amongst infants of diabetic mothers (IDMS) admitted into the Special Care Baby Unit of University of Port Harcourt Teaching Hospital...
2010: Italian Journal of Pediatrics
Chaturica Athukorala, Alice R Rumbold, Kristyn J Willson, Caroline A Crowther
BACKGROUND: The prevalence of obesity amongst women bearing children in Australia is rising and has important implications for obstetric care. The aim of this study was to assess the prevalence and impact of mothers being overweight and obese in early to mid-pregnancy on maternal, peripartum and neonatal outcomes. METHODS: A secondary analysis was performed on data collected from nulliparous women with a singleton pregnancy enrolled in the Australian Collaborative Trial of Supplements with antioxidants Vitamin C and Vitamin E to pregnant women for the prevention of pre-eclampsia (ACTS)...
2010: BMC Pregnancy and Childbirth
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