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Relative age effect in children

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https://www.readbyqxmd.com/read/29453114/levetiracetam-monotherapy-for-the-treatment-of-infants-with-epilepsy
#1
Pinar Arican, Pinar Gencpinar, Dilek Cavusoglu, Nihal Olgac Dundar
PURPOSE: Levetiracetam is a broad-spectrum anti-epileptic drug that is effective against both focal and generalized epilepsies. In this study, we aimed to evaluate the efficacy, tolerability and safety of levetiracetam monotherapy in the management of different seizure types in children with epilepsy under the age of two. METHOD: This retrospective study was conducted on children with a diagnosis of epilepsy from January 2014 to January 2017. To be included in the study, patients were required to be less than two years of age at the time levetiracetam was initiated as initial monotherapy and to be followed clinically for at least 6 months...
February 12, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29452999/chylothorax-as-a-risk-factor-for-thrombosis-in-adults-a-proof-of-concept-study
#2
Sumedh S Hoskote, Hemang Yadav, Prashant Jagtap, Dennis A Wigle, Craig E Daniels
BACKGROUND: Postoperative chylothorax in children is associated with an increased risk of vascular thrombosis, hypothesized to be from loss of antithrombin into chylous fluid resulting in a hypercoagulable state. In adults, an increased thrombotic risk with chylothorax has not been described. Adults undergoing Ivor-Lewis esophagogastrectomy have two strong thrombotic risk factors-active malignancy and postoperative state-allowing for relative homogeneity in baseline thrombotic risk; therefore, we studied the association of chylothorax with thrombosis in this population...
February 13, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29452463/autosomal-dominant-mannose-binding-lectin-deficiency-is-associated-with-worse-neurodevelopmental-outcomes-after-cardiac-surgery-in-infants
#3
Daniel Seung Kim, Yatong K Li, Jerry H Kim, Curtis S Bergquist, Marsha Gerdes, Judy C Bernbaum, Nancy Burnham, Donna M McDonald-McGinn, Elaine H Zackai, Susan C Nicolson, Thomas L Spray, Deborah A Nickerson, Hakon Hakonarson, Gail P Jarvik, J William Gaynor
OBJECTIVES: The MBL2 gene is the major genetic determinant of mannose-binding lectin (MBL)-an acute phase reactant. Low MBL levels have been associated with adverse outcomes in preterm infants. The MBL2 Gly54Asp missense variant causes autosomal dominant MBL deficiency. We tested the hypothesis that MBL2 Gly54Asp is associated with worse neurodevelopmental outcomes after cardiac surgery in neonates. METHODS: This is an analysis of a previously described cohort of patients with nonsyndromic congenital heart disease who underwent cardiac surgery with cardiopulmonary bypass before age 6 months (n = 295)...
March 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29452149/facial-gender-but-not-emotion-distinguishes-neural-responses-of-10-to-13-year-old-children-with-social-anxiety-disorder-from-healthy-and-clinical-controls
#4
Verena Keil, Andero Uusberg, Jens Blechert, Brunna Tuschen-Caffier, Julian Schmitz
OBJECTIVE: The current study examined neural and behavioral responses to angry, happy and neutral faces in childhood social anxiety disorder (SAD). METHOD: Behavioral (reaction time and accuracy) and electrocortical measures (P100, N170, EPN, LPP) were assessed during a facial emotion identification task in children (age 10-13) with SAD (n = 32), clinical controls with mixed anxiety disorders (n = 30), and healthy controls (n = 33). RESULTS: Overall, there were no group differences in behavioral or neural responses to emotional faces...
February 13, 2018: Biological Psychology
https://www.readbyqxmd.com/read/29451694/children-with-facial-morphea-managing-everyday-life-a-qualitative-study
#5
E Stasiulis, B Gladstone, K Boydell, C O'Brien, E Pope, R Laxer
BACKGROUND: This study explores the everyday experiences of children with facial morphea by examining the psychosocial impact of living with facial morphea and how children and their families manage its impact. METHODS: We used a qualitative, social constructionist approach involving focus groups, in-depth interviews and drawing activities with 10 children with facial morphea 8-17 years of age and 13 parents. Interpretive thematic analysis was utilized to examine the data...
February 16, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29450728/winter-vitamin-d-3-supplementation-does-not-increase-muscle-strength-but-modulates-the-igf-axis-in-young-children
#6
Charlotte Mortensen, Christian Mølgaard, Hanne Hauger, Michael Kristensen, Camilla T Damsgaard
PURPOSE: To explore whether muscle strength, the insulin-like growth factor axis (IGF-axis), height, and body composition were associated with serum 25-hydroxyvitamin D [25(OH)D] and affected by winter vitamin D supplementation in healthy children, and furthermore to explore potential sex differences. METHODS: We performed a double-blind, placebo-controlled, dose-response winter trial at 55ºN. A total of 117 children aged 4-8 years were randomly assigned to either placebo, 10, or 20 µg/day of vitamin D 3 for 20 weeks...
February 15, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29450238/the-direct-and-indirect-effect-of-loneliness-on-the-development-of-adolescent-alcohol-use-in-the-united-kingdom
#7
Michael T McKay, Svenja Konowalczyk, James R Andretta, Jon C Cole
Alcohol use among adolescents in the United Kingdom (UK) remains relatively high compared to those in other European countries. The present study sought to examine both the direct and indirect effect of loneliness on drinking behavior. Participants were school children (mean age 13.5 years at Time 1) participating in a Randomized Controlled Trial in the UK, who completed a battery of questionnaires examining alcohol-use indicators, loneliness, self-efficacy and sensation seeking at Time 1 and at +12 months...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29449820/headache-and-alexithymia-in-children-and-adolescents-what-is-the-connection
#8
REVIEW
Giulia Natalucci, Noemi Faedda, Dario Calderoni, Rita Cerutti, Paola Verdecchia, Vincenzo Guidetti
Background: Headache is one of the most common complaints in children and adolescents and comorbidity rates are very high and the major associated diseases are depression, anxiety, atopic disorders, sleep, and behavioral disorders. In recent years, it has been highlighted that difficulties regulating emotions such as alexithymia have also been associated with diagnosis of somatization. Methods: We carried out a mini review analyzing the relation between alexithymia and primary headache (e.g., migraine and tension type headache) in children and adolescents by synthesizing the relevant studies in the literature on PubMed, PsycINFO, and Google Scholar...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29449277/modeling-early-postnatal-brain-growth-and-development-with-ct-changes-in-the-brain-radiodensity-histogram-from-birth-to-2-years
#9
K A Cauley, Y Hu, J Och, P J Yorks, S W Fielden
BACKGROUND AND PURPOSE: The majority of brain growth and development occur in the first 2 years of life. This study investigated these changes by analysis of the brain radiodensity histogram of head CT scans from the clinical population, 0-2 years of age. MATERIALS AND METHODS: One hundred twenty consecutive head CTs with normal findings meeting the inclusion criteria from children from birth to 2 years were retrospectively identified from 3 different CT scan platforms...
February 15, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29449199/implementation-of-digital-awareness-strategies-to-engage-patients-and-providers-in-a-lung-cancer-screening-program-retrospective-study
#10
Dana L Jessup, McKinley Glover Iv, Dania Daye, Lynda Banzi, Philip Jones, Garry Choy, Jo-Anne O Shepard, Efrén J Flores
BACKGROUND: Lung cancer is the leading cause of cancer-related deaths in the United States. Despite mandated insurance coverage for eligible patients, lung cancer screening rates remain low. Digital platforms, including social media, provide a potentially valuable tool to enhance health promotion and patient engagement related to lung cancer screening (LCS). OBJECTIVE: The aim was to assess the effectiveness of LCS digital awareness campaigns on utilization of low-dose computed tomography (LDCT) and visits to institutional online educational content...
February 15, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29446662/parents-knowledge-and-beliefs-about-the-impact-of-exposure-to-media-violence-on-children-s-aggression
#11
Nahla Mansour Al-Ali, Hadeel Said Yaghy, Khulood K Shattnawi, Noha M Al-Shdayfat
The current study aimed to assess Jordanian parents' knowledge and beliefs about the effects of violent media on children's aggressive behavior. A sample of 262 parents of children aged 6-11 years completed a Media Quotient questionnaire about children's media habits, media effects, and children's aggressive behavior. Parents reported that their children spend an average of 4.83 h (SD = 2.12) watching TV, 3.20 h (SD = 2.29) playing video games, 1.07 h (SD = 0.88) listening to music, and only 0.52 min (SD = 0...
February 15, 2018: Issues in Mental Health Nursing
https://www.readbyqxmd.com/read/29446439/vision-screening-for-correctable-visual-acuity-deficits-in-school-age-children-and-adolescents
#12
REVIEW
Jennifer R Evans, Priya Morjaria, Christine Powell
BACKGROUND: Although the benefits of vision screening seem intuitive, the value of such programmes in junior and senior schools has been questioned. In addition there exists a lack of clarity regarding the optimum age for screening and frequency at which to carry out screening. OBJECTIVES: To evaluate the effectiveness of vision screening programmes carried out in schools to reduce the prevalence of correctable visual acuity deficits due to refractive error in school-age children...
February 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29446437/effects-of-total-fat-intake-on-bodyweight-in-children
#13
REVIEW
Celeste E Naude, Marianne E Visser, Kim A Nguyen, Solange Durao, Anel Schoonees
BACKGROUND: As part of efforts to prevent childhood overweight and obesity, we need to understand the relationship between total fat intake and body fatness in generally healthy children. OBJECTIVES: To assess the effects of total fat intake on measures of weight and body fatness in children and young people not aiming to lose weight. SEARCH METHODS: For this update we revised the previous search strategy and ran it over all years in the Cochrane Library, MEDLINE (Ovid), MEDLINE (PubMed), and Embase (Ovid) (current to 23 May 2017)...
February 15, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29446323/conners-3-self-report-scale-an-empirical-support-to-the-dimensionality-of-the-content-scales
#14
Viola Angela Izzo, Maria Anna Donati, Caterina Primi
The Conners' Rating Scales are one of the most used instruments for attention deficit/hyperactivity disorder (ADHD). Nonetheless, in the latest edition, the Inattention scale was not statistically supported. This study examined the dimensionality of the Italian version of the Conners 3-Self-Report scale testing both a five-factor structure including Inattention and a four-factor model combining Inattention and Learning Problems. Moreover, the generalizability of the detected structure through measurement invariance was verified...
February 1, 2018: Clinical Child Psychology and Psychiatry
https://www.readbyqxmd.com/read/29446267/skin-irritation-from-a-facial-mask-in-class-iii-malocclusion-evaluation-of-individual-silicone-chin-cups-in-a-group-of-100-children
#15
Gaetano Ierardo, Valeria Luzzi, Iole Vozza, Antonella Polimeni, Maurizio Bossù
BACKGROUND: Reverse headgear (a facial mask) is one of the most frequently used interceptive orthodontic devices in patients with Class III malocclusion. It is a simple device but may present some drawbacks related to pressure on the skin generated by the forehead and chin supports linked to the maxillary intraoral appliance by elastics. This can cause injury to the chin and lips. METHODS: Patients between 7 and 8 years of age were selected from the Unit of Pediatric Dentistry...
April 2018: Minerva Stomatologica
https://www.readbyqxmd.com/read/29446116/does-integrated-academic-and-health-education-prevent-substance-use-systematic-review-and-meta-analyses
#16
REVIEW
G J Melendez-Torres, T Tancred, A Fletcher, J Thomas, R Campbell, C Bonell
BACKGROUND: Prevention of substance (alcohol, tobacco, illegal/legal drug) use in adolescents is a public health priority. As the scope for school-based health education is constrained in school timetables, interventions integrating academic and health education have gained traction in the UK and elsewhere, though evidence for their effectiveness remains unclear. We sought to synthesize the effectiveness of interventions integrating academic and health education for the prevention of substance use...
February 15, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29444257/comparison-of-strategies-and-incidence-thresholds-for-vi-conjugate-vaccines-against-typhoid-fever-a-cost-effectiveness-modeling-study
#17
Nathan C Lo, Ribhav Gupta, Jeffrey D Stanaway, Denise O Garrett, Isaac I Bogoch, Stephen P Luby, Jason R Andrews
Background: Typhoid fever remains a major public health problem globally. While new Vi conjugate vaccines hold promise for averting disease, the optimal programmatic delivery remains unclear. We aimed to identify the strategies and associated epidemiologic conditions under which Vi conjugate vaccines would be cost-effective. Methods: We developed a dynamic, age-structured transmission and cost-effectiveness model that simulated multiple vaccination strategies with a typhoid Vi conjugate vaccine from a societal perspective...
February 12, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29444224/a-systematic-review-with-meta-analysis-of-the-prevalence-of-gastroesophageal-reflux-in-congenital-diaphragmatic-hernia-pediatric-survivors
#18
J V Arcos-Machancoses, C Ruiz Hernández, J Martin de Carpi, S Pinillos Pisón
Congenital diaphragmatic hernia survivors are a well-known group at risk for developing gastroesophageal reflux disease that may be particularly long-term severe. The aim of this study is to provide a systematic review of the prevalence of gastroesophageal reflux in infant and children survivors treated for congenital diaphragmatic hernia.Electronic and manual searches were performed with keywords related to congenital diaphragmatic hernia, gastroesophageal reflux disease, and epidemiology terms. Summary estimates of the prevalence were calculated...
February 9, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29443747/supraglottoplasty-in-neonates-and-infants-a-radiofrequency-ablation-approach
#19
Shilei Pu, Hongming Xu, Xiaoyan Li
BACKGROUND: Supraglottoplasty is the mainstay of surgical treatment for laryngomalacia. A novel supraglottoplasty surgical technique is needed to achieve better efficacy. The purpose of this study was to introduce modified microscopic radiofrequency ablation supraglottoplasty (MMRAS) for the treatment of congenital laryngomalacia and to evaluate the outcome and effectiveness of this novel approach. METHODS: Seventeen children with severe laryngomalacia who underwent MMRAS were studied retrospectively...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443691/the-effect-of-emotion-on-articulation-rate-in-persistence-and-recovery-of-childhood-stuttering
#20
Aysu Erdemir, Tedra A Walden, Caswell M Jefferson, Dahye Choi, Robin M Jones
PURPOSE: This study investigated the possible association of emotional processes and articulation rate in pre-school age children who stutter and persist (persisting), children who stutter and recover (recovered) and children who do not stutter (nonstuttering). METHODS: The participants were ten persisting, ten recovered, and ten nonstuttering children between the ages of 3-5 years; who were classified as persisting, recovered, or nonstuttering approximately 2-2...
November 22, 2017: Journal of Fluency Disorders
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