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Yu-Ming Zhang, Bo Gao, Juan-Juan Wang, Xu-de Sun, Xi-Wen Liu
OBJECTIVE: The aim of this study was to compare the effects of hypotensive and normotensive resuscitation with a novel combination of fluids via lactate Ringer's solution (LRS), 6% hydroxyethyl starch 130/0.4 solution (HES), and 7.5% hypertonic saline solution (HSS) at early stage of uncontrolled hemorrhagic shock (UHS) before hemostasis. METHODS: New Zealand white rabbits (nā€Š=ā€Š32) underwent UHS by transecting the splenic parenchyma, followed by blood withdrawal via the femoral artery to target mean arterial pressure (MAP) of 40-45 mmHg...
2013: PloS One
Satya Krishna Ramachandran, Naeem Haider, Kelly A Saran, Michael Mathis, Joyce Kim, Michelle Morris, Michael O'Reilly
STUDY OBJECTIVE: To identify risk factors for life-threatening critical respiratory events occurring during parenteral analgesic therapy for acute postoperative pain. DESIGN: Retrospective, observational, cohort study. SETTING: University hospital. MEASUREMENTS: The electronic records of patients with sudden-onset, life-threatening critical respiratory events during analgesic therapy for postoperative pain were studied...
May 2011: Journal of Clinical Anesthesia
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