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https://www.readbyqxmd.com/read/27915493/overweightness-obesity-and-arterial-stiffness-in-healthy-subjects-a-systematic-review-and-meta-analysis-of-literature-studies
#1
Ping Li, Lei Wang, Chao Liu
OBJECTIVE: The relationship between overweightness, obesity and arterial stiffness remains unclear. We performed a meta-analysis evaluating the impact of obesity/overweightness on arterial stiffness in healthy subjects. METHODS: Literature searches were conducted using databases (eg, MEDLINE, EMBASE) and citations cross-referenced. Studies evaluating the relationship between obesity/overweightness and cfPWV, baPWV, and AIx were systematically searched. A total of 10 studies (1,124 obese/overweight subjects, 1,884 controls) were included...
December 3, 2016: Postgraduate Medicine
https://www.readbyqxmd.com/read/27906838/arterial-stiffness-index-beta-and-cardio-ankle-vascular-index-inherently-depend-on-blood-pressure-but-can-be-readily-corrected
#2
Bart Spronck, Alberto P Avolio, Isabella Tan, Mark Butlin, Koen D Reesink, Tammo Delhaas
OBJECTIVES: Arterial stiffness index β and cardio-ankle vascular index (CAVI) are widely accepted to quantify the intrinsic exponent (β0) of the blood pressure (BP)-diameter relationship. CAVI and β assume an exponential relationship between pressure (P) and diameter (d). We aim to demonstrate that, under this assumption, β and CAVI as currently implemented are inherently BP-dependent and to provide corrected, BP-independent forms of CAVI and β. METHODS AND RESULTS: In P = Prefe, usually reference pressure (Pref) and reference diameter (dref) are substituted with DBP and diastolic diameter to accommodate measurements...
January 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/27906007/what-happens-to-cardiovascular-system-behind-the-undetectable-level-of-hiv-viremia
#3
REVIEW
Gabriella d'Ettorre, Giancarlo Ceccarelli, Paolo Pavone, Pietro Vittozzi, Gabriella De Girolamo, Ivan Schietroma, Sara Serafino, Noemi Giustini, Vincenzo Vullo
Despite the combined antiretroviral therapy has improved the length and quality of life of HIV infected patients, the survival of these patients is always decreased compared with the general population. This is the consequence of non-infectious illnesses including cardio vascular diseases. In fact large studies have indicated an increased risk of coronary atherosclerotic disease, myocardial infarction even in HIV patients on cART. In HIV infected patients several factors may contribute to the pathogenesis of cardiovascular problems: life-style, metabolic parameters, genetic predisposition, viral factors, immune activation, chronic inflammation and side effects of antiretroviral therapy...
April 27, 2016: AIDS Research and Therapy
https://www.readbyqxmd.com/read/27904845/cardio-thoracic-surgical-experience-in-gabon
#4
REVIEW
François Ondo N'Dong, Sylvestre Mbamendame, Silvère Ngakani Offobo, Mory Mamadi Kaba, Jean Bernard Mbourou, Charles Diané
Our experience in cardio-thoracic surgery focuses on thoracic activity. The minimum fare for traumatisms, infectious pathology and tumoral pathology requires, for its improvement, the acquisition of a technical platform and of an adequate medical infrastructure, with a rational organisation of the care sequence. Vascular surgery calls for the training of qualified human resources, and the great demand in heart surgery calls upon the public powers for the construction of infrastructures, and the formation of necessary superstructures...
October 2016: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/27904026/inverse-relationship-between-sleep-duration-and-cardio-ankle-vascular-index-in-children
#5
Noriteru Morita, Isao Kambayashi, Tomoyasu Okuda, Shiro Oda, Shingo Takada, Toshihiro Nakajima, Noriyuki Shide, Hisashi Shinkaiya, Koichi Okita
AIM: Poor sleep has been shown to be associated with the development of cardiovascular risk factors, such as obesity, in both adults and children. This study aimed to investigate the relationship between sleep duration and arterial stiffness indices in Japanese children and early adolescents. METHODS: The data on 102 students (56 males, 46 females; mean age, 11.9±1.8 years) were analyzed. As non-invasive arterial stiffness parameters, the cardio-ankle vascular index (CAVI) and heart-ankle pulse wave velocity (haPWV) were evaluated...
December 1, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27893829/sansevieria-roxburghiana-schult-schult-f-family-asparagaceae-attenuates-type-2-diabetes-and-its-associated-cardiomyopathy
#6
Niloy Bhattacharjee, Ritu Khanra, Tarun K Dua, Susmita Das, Bratati De, M Zia-Ul-Haq, Vincenzo De Feo, Saikat Dewanjee
BACKGROUND: Sansevieria roxburghiana Schult. & Schult. F. (Family: Asparagaceae) rhizome has been claimed to possess antidiabetic activity in the ethno-medicinal literature in India. Therefore, present experiments were carried out to explore the protective role of edible (aqueous) extract of S. roxburghiana rhizome (SR) against experimentally induced type 2 diabetes mellitus (T2DM) and its associated cardiomyopathy in Wistar rats. METHODS: SR was chemically characterized by GC-MS analysis...
2016: PloS One
https://www.readbyqxmd.com/read/27882423/cardio-ankle-vascular-index-cavi-and-plasma-transforming-growth-factor-%C3%AE-1-tgf-%C3%AE-1-level-correlate-with-aortopathy-in-adults-with-repaired-tetralogy-of-fallot
#7
Yumi Shiina, Koichiro Niwa
It is challenging to evaluate aortopathy in congenital heart disease using conventional investigations such as brachial-ankle pulse wave velocity (baPWV). Therefore, we evaluated the cardio-ankle vascular index (CAVI), a dimension of the ascending aorta and plasma transforming growth factor-β1 (TGF-β1) level, in order to find novel noninvasive parameters of aortopathy in adults with repaired tetralogy of Fallot (TOF). Prospectively, we enrolled 42 consecutive adults with TOF (28 patients with repaired TOF were not on ARB, 8 patients with repaired TOF on ARB, 6 patients with no repair or only palliative repair) and 20 age-matched healthy controls...
November 24, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27874917/traitement-analg%C3%A3-sique-apr%C3%A3-s-des-interventions-en-m%C3%A3-decine-dentaire
#8
Claudio Rostetter, Heinz-Theo Lübbers, Philipp Metzler
This script gives a pragmatic advice for dentists on pain control and anti-inflammation treatment considering current literature and state of the art of analgesic treatment. Naproxen seems to be the feasible anti-inflammatory painkiller as it has a lower cardio-vascular risk profile compared to other NSAID. The higher gastrointestinal bleeding risk can be mitigated using proton-pump inhibitors. Additionally, the duration of the drug effect of about 12–15 hours allows excellent patient compliance and comfort in comparison to other NSAID...
2016: Swiss Dental Journal
https://www.readbyqxmd.com/read/27873019/arterial-stiffness-in-young-adult-swimmers
#9
Masato Nishiwaki, Keisuke Takahara, Naoyuki Matsumoto
PURPOSE: Habitual Aerobic exercise reduces arterial stiffness, but effects of habitual swimming on arterial stiffness are not yet fully understood. Swimming can also increase systolic blood pressure (BP) in normotensive individuals. Accordingly, this cross-sectional study aimed to investigate arterial stiffness in young adult swimmers after considering the influence of BP. METHODS: Participants comprised 41 men (18-21 years), including 15 untrained controls (C), 11 competitive cyclists (aerobic-trained athletes; A), and 15 competitive swimmers (S)...
November 21, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27866565/regional-differences-in-the-prevalence-of-cardiovascular-disease
#10
Christina Dornquast, Lars E Kroll, Hannelore K Neuhauser, Stefan N Willich, Thomas Reinhold, Markus A Busch
BACKGROUND: Cardiovascular disease continues to be the single most common cause of death and to account for the largest single portion of treatment costs in Germany. Reliable data on regional differences in the frequency of cardio - vascular disease are important for the planning of targeted care structures and preventive measures. METHODS: Pooled data from the German Health Update (GEDA), a nationwide telephone health survey conducted in 2009, 2010 and 2012 (n = 62 214) were used to estimate the lifetime prevalence of major cardiovascular disease (self-reported medical diagnosis of myocardial infarction, other coronary heart disease, stroke, or congestive heart failure) in each of the German federal states...
October 21, 2016: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/27864310/low-tlr7-gene-expression-in-atherosclerotic-plaques-is-associated-with-major-adverse-cardio-and-cerebrovascular-events
#11
Glykeria Karadimou, Lasse Folkersen, Martin Berg, Ljubica Perisic, Andrea Discacciati, Joy Roy, Göran K Hansson, Jonas Persson, Gabrielle Paulsson-Berne
AIMS: Processes in the development of atherosclerotic lesions can lead to plaque rupture or erosion, which can in turn elicit myocardial infarction or ischaemic stroke. The aims of this study were to determine whether Toll-like receptor 7 (TLR7) gene expression levels influence patient outcome and to explore the mechanisms linked to TLR7 expression in atherosclerosis. METHODS AND RESULTS: Atherosclerotic plaques were removed by carotid endarterectomy (CEA) and subjected to gene array expression analysis (n=123)...
November 15, 2016: Cardiovascular Research
https://www.readbyqxmd.com/read/27854113/epidemiology-clinical-features-associated-comorbidities-and-treatment
#12
Guy Shalom
INTRODUCTION: Hidradenitis suppurativa (HS) is a chronic relapsing suppurativa skin disease localized in the apocrine-gland-bearing areas of the body, predominantly in the axillae and groin. EVIDENCE ACQUISITION: Although important risk factors have been identified, the pathomechanisms of the disease have not been fully understood. In the absence of proper treatment chronic inflammation results in debilitating, and sometimes life-threatening complications. EVIDENCE SYNTHESIS: This severe and chronic disease can have detrimental effects on self-esteem and quality of life and is associated with high comorbidity, such as the metabolic syndrome and its components...
November 17, 2016: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/27846043/aortic-stiffness-and-blood-pressure-variability-in-young-people-a-multimodality-investigation-of-central-and-peripheral-vasculature
#13
Henry Boardman, Adam J Lewandowski, Merzaka Lazdam, Yvonne Kenworthy, Polly Whitworth, Charlotte L Zwager, Jane M Francis, Christina Y L Aye, Wilby Williamson, Stefan Neubauer, Paul Leeson
INTRODUCTION: Increased blood pressure (BP) variability is a cardiovascular risk marker for young individuals and may relate to the ability of their aorta to buffer cardiac output. We used a multimodality approach to determine relations between central and peripheral arterial stiffness and BP variability. METHODS: We studied 152 adults (mean age of 31 years) who had BP variability measures based on SD of awake ambulatory BPs, 24-h weighted SD and average real variability (ARV)...
November 23, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27834123/translational-applications-of-tissue-engineering-in-cardiovascular-medicine
#14
Y Murat Elçin, Arin Dogan, Eser Elçin
Cardiovascular diseases are the leading cause of worldwide deaths. Current paradigm in medicine seeks novel approaches for the treatment of progressive or end-stage diseases. The organ transplantation option is limited in availability and unfortunately, a great number of patients are lost while waiting for donor organs. Animal studies have shown that upon myocardial infarction, it may be possible to stop adverse remodeling in its tracks and reverse with tissue engineering methods. Regaining the myocardium function and avoiding further deterioration towards heart failure can benefit millions of people with a significantly lesser burden on healthcare systems worldwide...
November 11, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27833755/measurement-of-overweight-and-obesity-an-urban-slum-setting-in-sub-saharan-africa-a-comparison-of-four-anthropometric-indices
#15
Tilahun Nigatu Haregu, Samuel Oti, Thaddaeus Egondi, Catherine Kyobutungi
BACKGROUND: As a result of both genetic and environmental factors, the body composition and topography of African populations are presumed to be different from western populations. Accordingly, globally accepted anthropometric markers may perform differently in African populations. In the era of rapid emergence of cardio-vascular diseases in sub-Saharan Africa, evidence about the performance of these markers in African settings is essential. The aim of this study was to investigate the inter-relationships among the four main anthropometric indices in measuring overweight and obesity in an urban poor African setting...
2016: BMC Obesity
https://www.readbyqxmd.com/read/27832203/angiotensin-converting-enzyme-inhibitors-angiotensin-receptor-blockers-and-calcium-channel-blockers-are-associated-with-prolonged-vascular-access-patency-in-uremic-patients-undergoing-hemodialysis
#16
Fu-An Chen, Chih-Chiang Chien, Yu-Wei Chen, Yu-Te Wu, Chih-Ching Lin
BACKGROUND: Vascular access failure is a huge burden for patients undergoing hemodialysis. Many efforts have been made to maintain vascular access patency, including pharmacotherapy. Angiotensin converting enzyme inhibitor (ACE-I), angiotensin receptor blocker (ARB), and calcium channel blocker (CCB) are known for their antihypertensive and cardio-protective effects, however, their effects on long-term vascular access patency are still inconclusive. DESIGN, SETTING, PARTICIPANTS AND MEASUREMENTS: We retrospectively enrolled patients commencing maintenance hemodialysis between January 1, 2000, and December 31, 2006 by using National Health Insurance Research Database in Taiwan...
2016: PloS One
https://www.readbyqxmd.com/read/27829641/arterial-stiffness-is-significantly-associated-with-left-ventricular-diastolic-dysfunction-in-patients-with-cardiovascular-disease
#17
Takayuki Namba, Nobuyuki Masaki, Yuki Matsuo, Atsushi Sato, Toyokazu Kimura, Shunpei Horii, Risako Yasuda, Hirotaka Yada, Akio Kawamura, Bonpei Takase, Takeshi Adachi
Left ventricular (LV) diastolic dysfunction is considered the main cause of heart failure with preserved ejection fraction (HFpEF). There have been few reports on the correlation between LV diastolic dysfunction and arterial stiffness in patients with clinical cardiovascular disease.This cross-sectional study enrolled 100 patients (67 men, 33 women; mean age, 70 years). All participants were diagnosed with cardiovascular disease. A total of 89 (89%) patients had coronary artery disease or HF. Patients with reduced EF and valvular disease were excluded...
November 9, 2016: International Heart Journal
https://www.readbyqxmd.com/read/27817745/cell-free-circulating-epigenomic-signatures-non-invasive-biomarker-for-cardiovascular-and-other-age-related-chronic-diseases
#18
Arpit Bhargava, Naveen Kumar Khare, Neha Bunkar, Koel Chaudhury, Kailash Chand Pandey, Subodh Kumar Jain, Pradyumna Kumar Mishra
The burden of cardio-vascular and other age-related non-communicable diseases are rapidly increasing worldwide. Majority of these chronic ailments are curable, if diagnosed at early stages. Candidate biomarkers of early detection are therefore essential for identification of high-risk individuals, prompt and accurate disease diagnosis, and to monitor therapeutic response. The functional significance of circulating nucleic acids that recapitulate specific disease profiles is now well established. But subtle changes in DNA sequence may not solely reflect the differentiation of gene expression patterns observed in diverse set of diseases as epigenetic phenomena play a larger role in aetiology and patho-physiology...
October 27, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27812043/diagnosis-trajectories-of-prior-multi-morbidity-predict-sepsis-mortality
#19
Mette K Beck, Anders Boeck Jensen, Annelaura Bach Nielsen, Anders Perner, Pope L Moseley, Søren Brunak
Sepsis affects millions of people every year, many of whom will die. In contrast to current survival prediction models for sepsis patients that primarily are based on data from within-admission clinical measurements (e.g. vital parameters and blood values), we aim for using the full disease history to predict sepsis mortality. We benefit from data in electronic medical records covering all hospital encounters in Denmark from 1996 to 2014. This data set included 6.6 million patients of whom almost 120,000 were diagnosed with the ICD-10 code: A41 'Other sepsis'...
November 4, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27810612/inflammatory-cardio-metabolic-and-diabetic-profiling-of-chronic-schizophrenia
#20
R Balõtšev, K Koido, V Vasar, S Janno, K Kriisa, R Mahlapuu, U Ljubajev, M Parksepp, P Veiksaar, V Volke, A Lang, L Haring, M Zilmer, E Vasar
BACKGROUND: There is a growing interest in low-grade inflammatory and metabolic alterations in patients with chronic schizophrenia (SCH). METHODS: Inflammatory (tumor-necrosis factor-α [TNF-α], interferon-γ [IFN-γ], interleukins [IL-1α, IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10], monocyte chemo-attractant protein-1 [MCP-1]) and growth factors (vascular endothelial growth factor [VEGF], epidermal growth factor [EGF]) were measured in blood serum samples of 105 SCH patients and 148 control subjects (CS)...
October 28, 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
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